US5001255A
(en)
*
|
1984-12-04 |
1991-03-19 |
Sandoz Pharm. Corp. |
Idene analogs of mevalonolactone and derivatives thereof
|
HUT48208A
(en)
*
|
1985-10-25 |
1989-05-29 |
Sandoz Ag |
Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds
|
US4751235A
(en)
*
|
1986-12-23 |
1988-06-14 |
Sandoz Pharm. Corp. |
Anti-atherosclerotic indolizine derivatives
|
US5091378A
(en)
*
|
1987-05-22 |
1992-02-25 |
E. R. Squibb & Sons, Inc. |
Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
|
US4904691A
(en)
*
|
1987-12-21 |
1990-02-27 |
Rorer Pharmaceutical Corporation |
Novel HMG-CoA reductase inhibitors
|
US4822799A
(en)
*
|
1988-01-27 |
1989-04-18 |
Sandoz Pharm. Corp. |
Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals
|
US4876280A
(en)
*
|
1988-03-10 |
1989-10-24 |
Sandoz Pharm. Corp. |
Arylcyclohexane and arylcyclohexene analogs of mevalonolactone derivatives and their use
|
US5506219A
(en)
*
|
1988-08-29 |
1996-04-09 |
E. R. Squibb & Sons, Inc. |
Pyridine anchors for HMG-CoA reductase inhibitors
|
EP0562643A3
(en)
*
|
1988-10-13 |
1994-05-18 |
Sandoz Ag |
7-substituted-hept-6-enoic and -heptanoic acids and derivatives thereof
|
FR2642065B1
(fr)
*
|
1989-01-24 |
1991-05-24 |
Lipha |
Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
|
US5025017A
(en)
*
|
1989-09-28 |
1991-06-18 |
E. R. Squibb & Sons, Inc. |
Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
|
US5189180A
(en)
*
|
1989-09-28 |
1993-02-23 |
E. R. Squibb & Sons, Inc. |
Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
|
JPH03173882A
(ja)
*
|
1989-09-29 |
1991-07-29 |
Tanabe Seiyaku Co Ltd |
クロメン又はチオクロメン誘導体、その製法及びその合成中間体
|
WO1992019240A1
(fr)
*
|
1991-05-01 |
1992-11-12 |
University Of New Mexico |
Traitement d'aberrations cellulaires avec des biomodulateurs
|
WO1992019239A1
(fr)
*
|
1991-05-01 |
1992-11-12 |
University Of New Mexico |
Traitement d'etats cellulaires aberrants a l'aide de biomodulateurs
|
US5256692A
(en)
*
|
1992-01-07 |
1993-10-26 |
E. R. Squibb & Sons, Inc. |
Sulfur-containing HMG-COA reductase inhibitors
|
US20010006644A1
(en)
|
1997-07-31 |
2001-07-05 |
David J. Bova |
Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
|
US7276249B2
(en)
|
2002-05-24 |
2007-10-02 |
Elan Pharma International, Ltd. |
Nanoparticulate fibrate formulations
|
ES2258141T3
(es)
|
2001-04-11 |
2006-08-16 |
Bristol-Myers Squibb Company |
Complejos de aminoacidos de glucosidos c-arilo para el tratamiento de la diabetes y procedimiento.
|
IL160917A0
(en)
|
2001-10-18 |
2004-08-31 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
US7238671B2
(en)
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
US6806381B2
(en)
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
EP1443919A4
(fr)
|
2001-11-16 |
2006-03-22 |
Bristol Myers Squibb Co |
Inhibiteurs doubles de la proteine de liaison des acides gras des adipocytes et de la proteine de liaison des acides gras des keratinocytes
|
US6831102B2
(en)
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
US6747048B2
(en)
|
2002-05-08 |
2004-06-08 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
US7057046B2
(en)
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
AU2003241477A1
(en)
|
2002-06-10 |
2003-12-22 |
Elan Pharma International, Ltd. |
Nanoparticulate polycosanol formulations and novel polycosanol combinations
|
WO2004037181A2
(fr)
|
2002-10-23 |
2004-05-06 |
Bristol-Myers Squibb Company |
Inhibiteurs de dipeptidyl peptidase iv a base de glycinenitrile et procedes correspondants
|
US7098235B2
(en)
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
DE60323536D1
(de)
|
2002-12-20 |
2008-10-23 |
Pfizer Prod Inc |
Dosierungsform enthaltend einen cetp-hemmer und einen hmg-coa reduktase hemmer
|
TW200504021A
(en)
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
US7557143B2
(en)
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
US7459474B2
(en)
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
EP2428516A1
(fr)
|
2003-11-19 |
2012-03-14 |
Metabasis Therapeutics, Inc. |
Nouvelles substances thyromimetiques contenant du phosphore
|
JP5697296B2
(ja)
|
2004-03-05 |
2015-04-08 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
高脂血症および高コレステロール血症に関連する障害または疾患を、副作用を最小限にしつつ処置するための方法
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
TW200611704A
(en)
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
US7145040B2
(en)
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
AR051446A1
(es)
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
US7517991B2
(en)
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
US7589088B2
(en)
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
WO2006076568A2
(fr)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Heterocycles bicycliques servant de modulateurs au recepteur de cannabinoides
|
WO2006076597A1
(fr)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Heterocycles bicycliques constituant des modulateurs des recepteurs cannabinoides
|
US7314882B2
(en)
|
2005-01-12 |
2008-01-01 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
WO2006078697A1
(fr)
|
2005-01-18 |
2006-07-27 |
Bristol-Myers Squibb Company |
Heterocycles bicycliques utilises comme modulateurs des recepteurs de cannabinoide
|
EP2527337A1
(fr)
|
2005-04-14 |
2012-11-28 |
Bristol-Myers Squibb Company |
Inhibiteurs de la 11-bêta hydroxystéroïde déshydrogénase de type I
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7629342B2
(en)
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
US7317012B2
(en)
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
US7572808B2
(en)
|
2005-06-17 |
2009-08-11 |
Bristol-Myers Squibb Company |
Triazolopyridine cannabinoid receptor 1 antagonists
|
US7452892B2
(en)
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
US7632837B2
(en)
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
US8618115B2
(en)
|
2005-10-26 |
2013-12-31 |
Bristol-Myers Squibb Company |
Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
|
US7488725B2
(en)
|
2005-10-31 |
2009-02-10 |
Bristol-Myers Squibb Co. |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US7553836B2
(en)
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
US8367112B2
(en)
|
2006-02-28 |
2013-02-05 |
Alkermes Pharma Ireland Limited |
Nanoparticulate carverdilol formulations
|
WO2007139589A1
(fr)
|
2006-05-26 |
2007-12-06 |
Bristol-Myers Squibb Company |
Modulateurs des récepteurs de glp-1 à libération prolongée
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
EP2089355A2
(fr)
|
2006-11-01 |
2009-08-19 |
Brystol-Myers Squibb Company |
Modulateurs de recepteur de glucocorticoide, d'activite ap-1 et/ou nf- kappa b, et leur utilisation
|
AR065809A1
(es)
|
2007-03-22 |
2009-07-01 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
CA2687964A1
(fr)
|
2007-06-01 |
2009-02-19 |
The Trustees Of Princeton University |
Traitement d'infections virales par modulation de voies metaboliques de cellules hotes
|
US20090011994A1
(en)
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
JP2010534722A
(ja)
|
2007-07-27 |
2010-11-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規グルコキナーゼ活性化薬およびその使用方法
|
CA2697551C
(fr)
|
2007-09-20 |
2013-03-12 |
Irm Llc |
Composes et compositions en tant que modulateurs de l'activite de gpr119
|
EP2209780B1
(fr)
|
2007-11-01 |
2014-01-01 |
Bristol-Myers Squibb Company |
Composes non steroïdiens utiles en tant que modulateurs de l'activite ap-1 et/ou nf- b du recepteur des glucocorticoïdes et leur utilisation
|
PE20091928A1
(es)
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
WO2010093601A1
(fr)
|
2009-02-10 |
2010-08-19 |
Metabasis Therapeutics, Inc. |
Nouveaux thyromimetiques contenant de l'acide sulfonique et methodes d'utilisation associees
|
SG174504A1
(en)
|
2009-03-27 |
2011-10-28 |
Bristol Myers Squibb Co |
Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors
|
WO2011014520A2
(fr)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Composés et compositions pouvant servir de modulateurs de l'activité du gpr119
|
MX2012004078A
(es)
|
2009-10-09 |
2012-07-25 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
US20120294936A1
(en)
|
2009-11-13 |
2012-11-22 |
Astrazeneca Uk Limited |
Reduced mass metformin formulations
|
CA2780939C
(fr)
|
2009-11-13 |
2018-06-12 |
Bristol-Myers Squibb Company |
Formulations de comprime bicouche
|
AU2010319377B2
(en)
|
2009-11-13 |
2014-10-23 |
Astrazeneca Ab |
Immediate release tablet formulations
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
CN102971313A
(zh)
|
2010-04-14 |
2013-03-13 |
百时美施贵宝公司 |
新颖的葡糖激酶激活剂及其使用方法
|
WO2012006398A2
(fr)
|
2010-07-09 |
2012-01-12 |
Bhv Pharma, Inc. |
Système d'administration à libération immédiate/retardée en combinaison pour des médicaments à courte demi-vie comprenant de la rémogliflozine
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
WO2014052619A1
(fr)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Dérivés et compositions de pipéridine comme modulateurs de l'activité de gpr119
|
DK3489226T3
(da)
|
2012-11-20 |
2021-04-26 |
Lexicon Pharmaceuticals Inc |
Hæmmere for natriumglucose-cotransporter 1
|
AR094054A1
(es)
*
|
2012-12-19 |
2015-07-08 |
H Lundbeck As |
6-cloro-3-(fenil-d₅)-inden-1-ona y uso de la misma
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
WO2016176656A2
(fr)
|
2015-04-30 |
2016-11-03 |
President And Fellows Of Harvard College |
Anticorps anti-ap2 et agents de liaison à l'antigène utilisables en vue du traitement d'affections métaboliques
|
MX2021000601A
(es)
|
2018-07-19 |
2021-04-13 |
Astrazeneca Ab |
Metodos de tratamiento de hfpef empleando dapagliflozina y composiciones que comprenden la misma.
|
SG11202102498UA
(en)
|
2018-09-26 |
2021-04-29 |
Lexicon Pharmaceuticals Inc |
Crystalline forms of n-(1 -((2-(dimethylamino)ethyl)amino)-2-m ethyl-1 -oopropan-2-yl)-4-(4-(2-methyl-5- (2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2h-pyran-2-yl)benzyl) phenl)butanamide and methods of their synthesis
|
EP3891134A1
(fr)
|
2018-12-03 |
2021-10-13 |
H. Lundbeck A/S |
Promédicaments de 4-((1r,3s)-6-chloro-3-phényl-2,3-dihydro-1h-inden-1-yl)-1,2,2-triméthylpipérazine et 4-((1/r,3s)-6-chloro-3-(phényl-d5)-2,3-dihydro-1h-inden-1-yl)-2,2-diméthy-1-(méthyl-d3)pipérazine
|