PH23660A - Homodisaccharide hypoglycemic agents - Google Patents

Homodisaccharide hypoglycemic agents

Info

Publication number
PH23660A
PH23660A PH33204A PH33204A PH23660A PH 23660 A PH23660 A PH 23660A PH 33204 A PH33204 A PH 33204A PH 33204 A PH33204 A PH 33204A PH 23660 A PH23660 A PH 23660A
Authority
PH
Philippines
Prior art keywords
homodisaccharide
hypoglycemic agents
homonojirimycin
protected
inhibitors
Prior art date
Application number
PH33204A
Other languages
English (en)
Inventor
Paul S Liu
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PH23660A publication Critical patent/PH23660A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Luminescent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH33204A 1984-12-18 1985-12-18 Homodisaccharide hypoglycemic agents PH23660A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/683,127 US4634765A (en) 1984-12-18 1984-12-18 Homodisaccharide hypoglycemic agents

Publications (1)

Publication Number Publication Date
PH23660A true PH23660A (en) 1989-09-27

Family

ID=24742682

Family Applications (1)

Application Number Title Priority Date Filing Date
PH33204A PH23660A (en) 1984-12-18 1985-12-18 Homodisaccharide hypoglycemic agents

Country Status (20)

Country Link
US (1) US4634765A (enExample)
EP (1) EP0186103B1 (enExample)
JP (1) JPS61158994A (enExample)
KR (1) KR900005607B1 (enExample)
CN (1) CN1016784B (enExample)
AT (1) ATE62249T1 (enExample)
AU (1) AU574246B2 (enExample)
CA (1) CA1240989A (enExample)
DE (1) DE3582420D1 (enExample)
DK (1) DK587085A (enExample)
ES (1) ES8706164A1 (enExample)
FI (1) FI80707C (enExample)
GR (1) GR853032B (enExample)
HU (1) HU194263B (enExample)
IE (1) IE58186B1 (enExample)
NO (1) NO162387B (enExample)
NZ (1) NZ214570A (enExample)
PH (1) PH23660A (enExample)
PT (1) PT81689B (enExample)
ZA (1) ZA859573B (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2181729B (en) * 1985-10-12 1990-04-04 Nippon Shinyaku Co Ltd Glucosylmoranoline derivatives and production thereof
JPS62242692A (ja) * 1986-04-15 1987-10-23 Nippon Shinyaku Co Ltd モラノリン誘導体の製造法
EP0344383A1 (en) * 1988-06-02 1989-12-06 Merrell Dow Pharmaceuticals Inc. Novel alpha-Glucosidase inhibitors
EP0345104B1 (en) * 1988-06-02 1995-11-02 Merrell Dow Pharmaceuticals Inc. Novel Alpha-glucosidase inhibitors
US4880917A (en) * 1988-07-01 1989-11-14 Merrell Dow Pharmaceuticals Inc. Process for hydrolyzing 2,6-dideoxy-2,6-iminoheptononitrile derivatives using trifluoroacetic acid and dinitrogen tetroxide
US4908439A (en) * 1988-09-16 1990-03-13 Merrell Dow Pharmaceuticals Inc. Synthesis of intermediate useful in the preparation of nojirimycin and related compounds
US5227479A (en) * 1989-12-20 1993-07-13 Merrell Dow Pharmaceuticals Inc. Process for the preparation of nojirimycin and related compounds
US5504078A (en) * 1990-06-08 1996-04-02 Merrell Dow Pharmaceuticals Inc. α-glucosidase inhibitors
PT1213020E (pt) * 1997-04-15 2009-04-24 Csir Compostos e composições farmacêuticas com actividade supressora do apetite
GB2355657B (en) * 1999-10-27 2004-07-28 Phytopharm Plc Inhibitors Of Gastric Acid Secretion
EP1181277A4 (en) 2000-03-31 2005-08-10 Univ Michigan State PROCESS FOR THE PREPARATION OF 1,5-DIDESOXY-1,5-IMINO HEXITOLS FROM OXIMES OR IMINES
GB2363985B (en) * 2000-06-30 2004-09-29 Phytopharm Plc Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
AP2007003979A0 (en) * 2004-11-23 2007-06-30 Warner Lambert Co 7-(2h-pyrazol-3-yl)-3,5-dihyroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for thetreatment of lipidemia
WO2008045015A1 (en) * 2005-06-08 2008-04-17 Amicus Therapeutics, Inc. Imino and amino sugar purification
CN101228173A (zh) * 2005-06-08 2008-07-23 阿米库斯治疗学公司 三氟甲磺酸酯化的化合物的稳定化
BRPI0613221A2 (pt) * 2005-06-08 2010-12-28 Amicus Therapeutics Inc furanose cristalina e método para produzir uma furanose cristalina
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
EP2368560A1 (en) 2007-03-12 2011-09-28 Zadec ApS An anti-diabetic extract of rooibos
DK2170930T3 (da) 2007-06-04 2012-11-05 Synergy Pharmaceuticals Inc Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2328910B1 (en) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
CA2799708A1 (en) 2010-05-21 2011-11-24 Pfizer Inc. 2-phenyl benzoylamides
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN102462726B (zh) * 2010-11-04 2016-03-09 中国医学科学院药物研究所 白树总生物碱及多羟基生物碱化合物的提取、分离及用途
WO2012120414A2 (en) 2011-03-04 2012-09-13 Pfizer Inc. Edn3-like peptides and uses thereof
EP2712362A4 (en) * 2011-05-13 2014-12-24 Glycom As MANUFACTURE OF LACTO-N-TETRAOSE
WO2013133685A1 (en) 2012-03-09 2013-09-12 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
BR112017003745A2 (pt) 2014-08-29 2017-12-05 Tes Pharma S R L inibidores de semialdeído descarboxilase de ácido alfa-amino-beta-carboximucônico
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN104530150A (zh) * 2015-01-14 2015-04-22 佛山市赛维斯医药科技有限公司 含胺基苯和双葡萄糖苷结构化合物、其制备方法和用途
JP2020500838A (ja) 2016-10-14 2020-01-16 ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ Α−アミノ−β−カルボキシムコン酸セミアルデヒドデカルボキシラーゼの阻害剤
IT201700078102A1 (it) 2017-07-11 2019-01-11 Dipharma Francis Srl Sintesi di un azazucchero e suoi intermedi
CN108828121B (zh) * 2018-06-14 2020-06-05 华润三九医药股份有限公司 一种白树药材中α-高野尻霉素的含量检测方法
KR20210111248A (ko) 2018-11-20 2021-09-10 테스 파마 에스.알.엘. α-아미노-β-카르복시뮤콘산 세미알데하이드 데카르복실라제의 저해제
CN119060040A (zh) 2019-01-18 2024-12-03 阿斯利康(瑞典)有限公司 Pcsk9抑制剂及其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065562A (en) * 1975-12-29 1977-12-27 Nippon Shinyaku Co., Ltd. Method and composition for reducing blood glucose levels
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE2848117A1 (de) * 1978-11-06 1980-05-14 Bayer Ag Derivate des 2-hydroxymethyl-3,4,5- trihydroxy-piperidins, ihre herstellung und verwendung zur beeinflussung des kohlenhydrat- und fettstoffwechsels
DE2942365A1 (de) * 1979-10-19 1981-05-14 Bayer Ag, 5090 Leverkusen 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB2064527B (en) * 1979-12-08 1984-05-02 Nippon Shinyaku Co Ltd Moranoline derivatives and process for preparation thereof
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.

Also Published As

Publication number Publication date
DK587085D0 (da) 1985-12-17
NO855087L (no) 1986-06-19
JPS61158994A (ja) 1986-07-18
HU194263B (en) 1988-01-28
ES550060A0 (es) 1987-06-01
PT81689B (pt) 1987-11-30
AU5081085A (en) 1986-06-26
FI80707B (fi) 1990-03-30
EP0186103A2 (en) 1986-07-02
CA1240989A (en) 1988-08-23
AU574246B2 (en) 1988-06-30
FI854944A0 (fi) 1985-12-13
IE853179L (en) 1986-06-18
GR853032B (enExample) 1986-04-18
PT81689A (en) 1986-01-01
CN85109548A (zh) 1986-07-09
KR900005607B1 (ko) 1990-07-31
NZ214570A (en) 1988-03-30
CN1016784B (zh) 1992-05-27
NO162387B (no) 1989-09-11
ATE62249T1 (de) 1991-04-15
ZA859573B (en) 1986-08-27
FI854944L (fi) 1986-06-19
ES8706164A1 (es) 1987-06-01
US4634765A (en) 1987-01-06
KR860004921A (ko) 1986-07-16
JPH0565519B2 (enExample) 1993-09-17
IE58186B1 (en) 1993-07-28
EP0186103A3 (en) 1988-02-03
DE3582420D1 (de) 1991-05-08
FI80707C (fi) 1990-07-10
DK587085A (da) 1986-06-19
EP0186103B1 (en) 1991-04-03
HUT40137A (en) 1986-11-28

Similar Documents

Publication Publication Date Title
EP0186103A3 (en) Homodisaccharide hypoglycemic agents
AU550080B2 (en) Elastomeric active agent delivery system
AU575668B2 (en) N - acylpyrrolidine compound
AU4825285A (en) Surfactant containing anhydrous drug systems
AU3755785A (en) Sodium hypophosphite modified acryic acid copolymers
GB8704038D0 (en) Protected enzyme systems
AU536200B2 (en) Compound having anthelmintic and acaricidal activities
AU5125685A (en) Inhibition of decomposition of hydrogen peroxide systems
DE3372774D1 (en) Modified oligosaccharides used as substrate for measuring alpha-amylase activity
AU574864B2 (en) Multiple solution intravenous system
AU6675381A (en) Protection of substrates from microorganisms
DE3563044D1 (en) Optically active di(3-chlor-2-oxypropyl-trimethyl-ammonium) tartrate
AU563995B2 (en) Hypotriglyceridemically active polysaccharides
AU4477385A (en) 4h-1,4-benzothiazines as inhibitors/stimulators of enzymatic reactions
AU3994085A (en) Compositions contenant des lipides actifs
EP0114389A3 (en) Substituted arylglyoxal derivatives
JPS5785084A (en) Wiring of active matrix substrate
SU1166473A1 (ru) ДИТИОАЦЕТИЛГИДРАЗОН α -КАМФОРХИНОНА, ПРОЯВЛЯЮЩИЙ ПРОТИВОГИПОКСИЧЕСКУЮ АКТИВНОСТЬ
PL239327A1 (en) Method of isolation of polyfungine from the culture of highefficient mutant of streptomyces noursei var. polifungini strain
AU2557084A (en) Production of alpha-amylase inhibitor-tendamistat from streptomyces
MTP997B (en) Protected enzyme systems
CA1266642C (en) MONOSACCHARIDE COMPOUNDS WITH IMMUNOSTIMULATING ACTION
IE861883L (en) Enzymes which catalyze the degradation of lignin
AU8315687A (en) Propagation of seedlings
IT8320426A0 (it) Composizione di policarbonato autoestinguente.