PH22105A - Naphtalene derivatives and method of use thereof - Google Patents
Naphtalene derivatives and method of use thereofInfo
- Publication number
- PH22105A PH22105A PH33266A PH33266A PH22105A PH 22105 A PH22105 A PH 22105A PH 33266 A PH33266 A PH 33266A PH 33266 A PH33266 A PH 33266A PH 22105 A PH22105 A PH 22105A
- Authority
- PH
- Philippines
- Prior art keywords
- sup
- formula
- compounds
- hydrogen atom
- disclosed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
- C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Lubricants (AREA)
- Fats And Perfumes (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP309085 | 1985-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PH22105A true PH22105A (en) | 1988-06-01 |
Family
ID=11547645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH33266A PH22105A (en) | 1985-01-10 | 1986-01-08 | Naphtalene derivatives and method of use thereof |
Country Status (18)
Country | Link |
---|---|
US (2) | US4771072A (zh) |
EP (1) | EP0188248B1 (zh) |
JP (3) | JPS61267541A (zh) |
KR (1) | KR890001884B1 (zh) |
CN (1) | CN1006464B (zh) |
AT (1) | ATE54441T1 (zh) |
AU (1) | AU584153B2 (zh) |
BG (2) | BG45383A3 (zh) |
DD (1) | DD270529A5 (zh) |
DE (1) | DE3672501D1 (zh) |
ES (2) | ES8705837A1 (zh) |
FI (1) | FI87557C (zh) |
HU (1) | HU196737B (zh) |
IL (1) | IL91117A0 (zh) |
MY (1) | MY101268A (zh) |
NO (1) | NO170760C (zh) |
PH (1) | PH22105A (zh) |
PT (1) | PT81814B (zh) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5011948A (en) * | 1985-04-12 | 1991-04-30 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
US4644072A (en) * | 1985-04-12 | 1987-02-17 | Bristol-Myers Company | Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof |
JPS6310746A (ja) * | 1986-07-01 | 1988-01-18 | Tanabe Seiyaku Co Ltd | ナフタレン誘導体 |
AT388372B (de) * | 1987-10-08 | 1989-06-12 | Tanabe Seiyaku Co | Neue naphthalinderivate und sie enthaltende pharmazeutika |
JPH01135766A (ja) * | 1987-11-20 | 1989-05-29 | Tanabe Seiyaku Co Ltd | ビフェニル誘導体 |
PH26342A (en) * | 1988-11-29 | 1992-04-29 | Univ Texas | Microbial cellulose modified during synthesis |
MY105057A (en) * | 1989-01-27 | 1994-07-30 | Tanabe Seiyaku Co | A process for preparing naphthalene derivatives |
US5003087A (en) * | 1989-02-03 | 1991-03-26 | Tanabe Seiyaku Co., Ltd. | Process for preparing a naphthalene derivative and a synthetic intermediate thereof |
US5227399A (en) * | 1991-02-28 | 1993-07-13 | Merck Frosst Canada, Inc. | Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0501579A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Naphthalene lactones as inhibitors of leukotriene biosynthesis |
US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
EP0501578A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
JP2839805B2 (ja) * | 1991-10-17 | 1998-12-16 | 塩野義製薬株式会社 | リグナン類縁体及びその製造方法ならびに抗高脂血症剤 |
US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
CA2121060C (en) * | 1993-04-16 | 2004-04-06 | Sachio Mori | Preparation of lignan analogues |
ID18046A (id) * | 1996-08-20 | 1998-02-19 | Takeda Chemical Industries Ltd | Senyawa siklik campuran, pembuatan dan penngunaannya. |
JP2002523408A (ja) | 1998-08-25 | 2002-07-30 | イェール ユニバーシティ | ヘリオキサンチンおよびその類似体によるb型肝炎ウイルスおよびフラビウイルスの阻害および治療 |
US6680344B1 (en) | 1999-06-01 | 2004-01-20 | The University Of Texas Southwestern Medical Center | Method of treating hair loss using diphenylmethane derivatives |
AU3712100A (en) | 1999-06-01 | 2000-12-18 | University Of Texas Southwestern Medical Center, The | Method of treating hair loss using sulfonyl thyromimetic compounds |
AU3507700A (en) | 1999-06-01 | 2000-12-18 | University Of Texas Southwestern Medical Center, The | Method of treating hair loss using diphenylether derivatives |
SE0102168D0 (sv) | 2001-06-19 | 2001-06-19 | Karolinska Innovations Ab | New use and new compounds |
KR20040032969A (ko) * | 2001-08-28 | 2004-04-17 | 상꾜 가부시키가이샤 | 안지오텐신 ii 수용체 길항제를 함유하는 의약 조성물 |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
ES2552657T3 (es) | 2010-05-26 | 2015-12-01 | Satiogen Pharmaceuticals, Inc. | Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias |
EP2770990A4 (en) | 2011-10-28 | 2015-03-11 | Lumena Pharmaceuticals Inc | Gallic acid refluxing agent for the treatment of hypertension and chronic liver disease |
EP2771003B1 (en) | 2011-10-28 | 2017-04-19 | Lumena Pharmaceuticals LLC | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
CA2907230A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease |
WO2014144485A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
WO2015153653A1 (en) * | 2014-03-31 | 2015-10-08 | Ohio State Innovation Foundation | Arylnaphthalene lactone derivatives and methods of making and using thereof |
US10682367B2 (en) | 2016-02-26 | 2020-06-16 | Ohio State Innovation Foundation | Antitumor arylnaphthalene ligand glycosides |
BR112021015815A2 (pt) | 2019-02-12 | 2022-01-18 | Mirum Pharmaceuticals Inc | Métodos para tratar colestase |
-
1985
- 1985-12-30 US US06/814,805 patent/US4771072A/en not_active Expired - Fee Related
- 1985-12-30 NO NO855355A patent/NO170760C/no unknown
- 1985-12-30 ES ES550578A patent/ES8705837A1/es not_active Expired
- 1985-12-31 AU AU51751/85A patent/AU584153B2/en not_active Ceased
-
1986
- 1986-01-08 PH PH33266A patent/PH22105A/en unknown
- 1986-01-08 JP JP61002624A patent/JPS61267541A/ja active Pending
- 1986-01-09 BG BG8673061A patent/BG45383A3/xx unknown
- 1986-01-09 KR KR1019860000074A patent/KR890001884B1/ko not_active IP Right Cessation
- 1986-01-09 FI FI860089A patent/FI87557C/fi not_active IP Right Cessation
- 1986-01-09 BG BG8782397A patent/BG45385A3/xx unknown
- 1986-01-09 PT PT81814A patent/PT81814B/pt not_active IP Right Cessation
- 1986-01-09 HU HU8690A patent/HU196737B/hu not_active IP Right Cessation
- 1986-01-10 CN CN86100090A patent/CN1006464B/zh not_active Expired
- 1986-01-10 AT AT86100282T patent/ATE54441T1/de not_active IP Right Cessation
- 1986-01-10 EP EP86100282A patent/EP0188248B1/en not_active Expired - Lifetime
- 1986-01-10 DE DE8686100282T patent/DE3672501D1/de not_active Expired - Fee Related
- 1986-09-03 ES ES557052A patent/ES8801239A1/es not_active Expired
-
1987
- 1987-07-15 MY MYPI87001017A patent/MY101268A/en unknown
-
1988
- 1988-01-15 DD DD88312249A patent/DD270529A5/de not_active IP Right Cessation
- 1988-12-08 JP JP63310353A patent/JPH0272136A/ja active Pending
- 1988-12-08 JP JP63310354A patent/JPH0272170A/ja active Granted
-
1989
- 1989-07-26 IL IL91117A patent/IL91117A0/xx unknown
-
1990
- 1990-01-02 US US07/459,859 patent/US5070103A/en not_active Expired - Fee Related
Also Published As
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