PH18918A - 2-acyl-azabicycloalkane-3-carboxylic acid derivatives,pharmaceutical compositions containing these compounds and their use - Google Patents

2-acyl-azabicycloalkane-3-carboxylic acid derivatives,pharmaceutical compositions containing these compounds and their use

Info

Publication number
PH18918A
PH18918A PH28321A PH28321A PH18918A PH 18918 A PH18918 A PH 18918A PH 28321 A PH28321 A PH 28321A PH 28321 A PH28321 A PH 28321A PH 18918 A PH18918 A PH 18918A
Authority
PH
Philippines
Prior art keywords
azabicycloalkane
acyl
compounds
carboxylic acid
pharmaceutical compositions
Prior art date
Application number
PH28321A
Other languages
English (en)
Inventor
Hansjorg Urbach
Rainer Henning
Rolf Geiger
Volker Teetz
Reinhard Becker
Holger Gaul
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25798350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH18918(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19813151690 external-priority patent/DE3151690A1/de
Priority claimed from DE19823210701 external-priority patent/DE3210701A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PH18918A publication Critical patent/PH18918A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
PH28321A 1981-12-29 1982-12-27 2-acyl-azabicycloalkane-3-carboxylic acid derivatives,pharmaceutical compositions containing these compounds and their use PH18918A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813151690 DE3151690A1 (de) 1981-12-29 1981-12-29 "neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung"
DE19823210701 DE3210701A1 (de) 1982-03-24 1982-03-24 2-azabicycloalkan-3-carbonsaeuren und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
PH18918A true PH18918A (en) 1985-11-06

Family

ID=25798350

Family Applications (2)

Application Number Title Priority Date Filing Date
PH28321A PH18918A (en) 1981-12-29 1982-12-27 2-acyl-azabicycloalkane-3-carboxylic acid derivatives,pharmaceutical compositions containing these compounds and their use
PH30781A PH19771A (en) 1981-12-29 1984-06-06 Azabicycloalkane carboxylic acids and esters

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH30781A PH19771A (en) 1981-12-29 1984-06-06 Azabicycloalkane carboxylic acids and esters

Country Status (27)

Country Link
US (3) US5008400A (xx)
EP (1) EP0084164B1 (xx)
JP (3) JPS58118569A (xx)
KR (1) KR890003424B1 (xx)
AR (1) AR247571A1 (xx)
AU (1) AU559140B2 (xx)
BG (1) BG60936B2 (xx)
CA (1) CA1341296C (xx)
CS (1) CS409591A3 (xx)
DE (2) DE3280014D1 (xx)
DK (2) DK170444B1 (xx)
DZ (1) DZ490A1 (xx)
ES (2) ES8308850A1 (xx)
FI (1) FI80017C (xx)
GR (1) GR78413B (xx)
HK (1) HK74989A (xx)
HU (1) HU194167B (xx)
IE (1) IE55867B1 (xx)
IL (1) IL67572A (xx)
LU (1) LU88263I2 (xx)
MA (1) MA19672A1 (xx)
NL (1) NL930048I2 (xx)
NO (1) NO156786C (xx)
NZ (1) NZ202903A (xx)
PH (2) PH18918A (xx)
PT (1) PT76052B (xx)
SG (1) SG1389G (xx)

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DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3211397A1 (de) * 1982-03-27 1983-11-10 Hoechst Ag, 6230 Frankfurt Spiro (4.(3+n))-2-aza-3-carbonsaeure-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE3211676A1 (de) * 1982-03-30 1983-10-06 Hoechst Ag Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
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DE3300774A1 (de) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung
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DE3324263A1 (de) * 1983-07-06 1985-01-17 Hoechst Ag, 6230 Frankfurt Derivate der 2-azabicyclo(3.1.0)hexan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(3.1.0)hexan-derivate als zwischenprodukte und verfahren zu deren herstellung
US4559340A (en) * 1983-11-25 1985-12-17 Schering Corporation Antihypertensive agents
DE3345355A1 (de) * 1983-12-15 1985-06-27 Hoechst Ag, 6230 Frankfurt Verfahren zur racematspaltung bicyclischer imino-(alpha)-carbonsaeureester

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DE3280014D1 (en) 1989-12-14
DK119992D0 (da) 1992-09-28
HU194167B (en) 1988-01-28
KR890003424B1 (ko) 1989-09-20
NO156786B (no) 1987-08-17
CA1341296C (en) 2001-09-25
NL930048I2 (nl) 1994-01-03
PT76052A (de) 1983-01-01
NL930048I1 (nl) 1993-09-01
JPH0587504B2 (xx) 1993-12-16
NO824394L (no) 1983-06-30
AU559140B2 (en) 1987-02-26
EP0084164A2 (de) 1983-07-27
JPS58118569A (ja) 1983-07-14
FI824474L (fi) 1983-06-30
DE3275293D1 (en) 1987-03-05
CS409591A3 (en) 1992-04-15
FI80017C (fi) 1990-04-10
AU9193182A (en) 1983-07-07
ES521740A0 (es) 1984-01-16
FI824474A0 (fi) 1982-12-27
PT76052B (de) 1985-11-28
DK171232B1 (da) 1996-08-05
KR840002810A (ko) 1984-07-21
ES8402271A1 (es) 1984-01-16
MA19672A1 (fr) 1983-07-01
ES518574A0 (es) 1983-10-01
BG60936B2 (bg) 1996-06-28
DK119992A (da) 1992-09-28
SG1389G (en) 1989-06-02
EP0084164B1 (de) 1987-01-28
IL67572A0 (en) 1983-05-15
JPH01301695A (ja) 1989-12-05
JPH01301659A (ja) 1989-12-05
ES8308850A1 (es) 1983-10-01
JPH064586B2 (ja) 1994-01-19
DK576782A (da) 1983-06-30
NZ202903A (en) 1988-01-08
IL67572A (en) 1992-08-18
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DZ490A1 (fr) 2004-09-13
US5101039A (en) 1992-03-31
US5008400A (en) 1991-04-16
GR78413B (xx) 1984-09-27
EP0084164A3 (en) 1983-10-12
LU88263I2 (xx) 1994-02-03
FI80017B (fi) 1989-12-29
AR247571A1 (es) 1995-01-31
HK74989A (en) 1989-09-22
IE823065L (en) 1983-06-29
US4933361A (en) 1990-06-12
NO156786C (no) 1987-11-25
PH19771A (en) 1986-06-27
IE55867B1 (en) 1991-02-14

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