PH17025A - Phenyl piperazine derivatives having anti-aggressive activity - Google Patents
Phenyl piperazine derivatives having anti-aggressive activityInfo
- Publication number
- PH17025A PH17025A PH23695A PH23695A PH17025A PH 17025 A PH17025 A PH 17025A PH 23695 A PH23695 A PH 23695A PH 23695 A PH23695 A PH 23695A PH 17025 A PH17025 A PH 17025A
- Authority
- PH
- Philippines
- Prior art keywords
- compounds
- piperazine derivatives
- phenyl piperazine
- hydrogen
- aggressive activity
- Prior art date
Links
- 230000002539 anti-aggressive effect Effects 0.000 title 1
- YZTJYBJCZXZGCT-UHFFFAOYSA-N phenylpiperazine Chemical class C1CNCCN1C1=CC=CC=C1 YZTJYBJCZXZGCT-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052736 halogen Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- -1 methoxy, ethoxy, amino Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7901633 | 1979-03-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH17025A true PH17025A (en) | 1984-05-17 |
Family
ID=19832723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH23695A PH17025A (en) | 1979-03-01 | 1980-02-28 | Phenyl piperazine derivatives having anti-aggressive activity |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0015615B1 (cs) |
| JP (1) | JPS55141478A (cs) |
| AT (1) | ATE2219T1 (cs) |
| AU (1) | AU532411B2 (cs) |
| CA (1) | CA1138461A (cs) |
| CS (1) | CS216525B2 (cs) |
| DD (1) | DD151408A5 (cs) |
| DE (1) | DE3061561D1 (cs) |
| DK (1) | DK84380A (cs) |
| ES (3) | ES8106898A1 (cs) |
| FI (1) | FI800588A7 (cs) |
| GR (1) | GR67005B (cs) |
| HU (1) | HU182070B (cs) |
| IE (1) | IE49526B1 (cs) |
| IL (1) | IL59489A (cs) |
| PH (1) | PH17025A (cs) |
| PL (1) | PL126161B1 (cs) |
| SU (1) | SU1039442A3 (cs) |
| YU (1) | YU54680A (cs) |
| ZA (1) | ZA801119B (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8005131A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met analgetische werking. |
| NL8005133A (nl) * | 1980-09-12 | 1982-04-01 | Duphar Int Res | Fenylpiperazinederivaten met antiagressieve werking. |
| US4457931A (en) * | 1982-09-27 | 1984-07-03 | Selvi & C. S.P.A. | Piperazine derivatives with anticholinergic and/or antihistaminic activity |
| JPH0660160B2 (ja) * | 1985-12-13 | 1994-08-10 | テルモ株式会社 | アミド誘導体およびこれを含有する抗アレルギ−剤 |
| US5382583A (en) * | 1989-04-22 | 1995-01-17 | John Wyeth & Brother, Limited | Piperazine derivatives |
| US5340812A (en) * | 1989-04-22 | 1994-08-23 | John Wyeth & Brother, Limited | Piperazine derivatives |
| DD297968A5 (de) * | 1989-04-22 | 1992-01-30 | �����@��������@�K@�����������@�������k�� | Neue piperazine, ihre herstellung und verwendung in pharmazeutischen mitteln |
| DE69033393T2 (de) * | 1989-04-22 | 2000-05-25 | American Home Products Corp., Madison | Tertiäre alkyl funktionalisierte Piperazin-Derivate |
| DK203990D0 (da) * | 1990-08-24 | 1990-08-24 | Novo Nordisk As | Piperazinylderivater |
| GB9200293D0 (en) * | 1992-01-08 | 1992-02-26 | Wyeth John & Brother Ltd | Piperazine derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2722529A (en) * | 1955-11-01 | Amides of certain l-amevoalkyl-x-phenyl | ||
| US2833770A (en) * | 1958-05-06 | Chj-chj | ||
| BE788280A (fr) * | 1971-09-04 | 1973-02-28 | Pfizer | Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant |
| GB1443598A (en) * | 1973-07-06 | 1976-07-21 | Acraf | 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine |
| FR2306694A1 (fr) * | 1975-04-07 | 1976-11-05 | Parcor | Derives de la piperazine |
-
1980
- 1980-02-25 AU AU55848/80A patent/AU532411B2/en not_active Ceased
- 1980-02-27 GR GR61296A patent/GR67005B/el unknown
- 1980-02-27 PL PL1980222294A patent/PL126161B1/pl unknown
- 1980-02-27 FI FI800588A patent/FI800588A7/fi not_active Application Discontinuation
- 1980-02-27 DK DK84380A patent/DK84380A/da not_active Application Discontinuation
- 1980-02-27 SU SU802890551A patent/SU1039442A3/ru active
- 1980-02-27 ZA ZA00801119A patent/ZA801119B/xx unknown
- 1980-02-27 ES ES488988A patent/ES8106898A1/es not_active Expired
- 1980-02-28 YU YU00546/80A patent/YU54680A/xx unknown
- 1980-02-28 CS CS801368A patent/CS216525B2/cs unknown
- 1980-02-28 PH PH23695A patent/PH17025A/en unknown
- 1980-02-28 IL IL59489A patent/IL59489A/xx unknown
- 1980-02-28 AT AT80200173T patent/ATE2219T1/de not_active IP Right Cessation
- 1980-02-28 DE DE8080200173T patent/DE3061561D1/de not_active Expired
- 1980-02-28 EP EP80200173A patent/EP0015615B1/en not_active Expired
- 1980-02-28 IE IE405/80A patent/IE49526B1/en unknown
- 1980-02-29 CA CA000346735A patent/CA1138461A/en not_active Expired
- 1980-02-29 HU HU80474A patent/HU182070B/hu unknown
- 1980-03-01 JP JP2466480A patent/JPS55141478A/ja active Pending
- 1980-03-03 DD DD80219413A patent/DD151408A5/de unknown
- 1980-09-16 ES ES495105A patent/ES8200883A1/es not_active Expired
- 1980-09-16 ES ES495106A patent/ES8200884A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IE800405L (en) | 1980-09-01 |
| DD151408A5 (de) | 1981-10-21 |
| DK84380A (da) | 1980-09-02 |
| IE49526B1 (en) | 1985-10-16 |
| PL222294A1 (cs) | 1980-12-01 |
| CA1138461A (en) | 1982-12-28 |
| IL59489A (en) | 1984-05-31 |
| ZA801119B (en) | 1981-09-30 |
| EP0015615B1 (en) | 1983-01-12 |
| PL126161B1 (en) | 1983-07-30 |
| AU532411B2 (en) | 1983-09-29 |
| GR67005B (cs) | 1981-05-18 |
| ES488988A0 (es) | 1981-09-01 |
| HU182070B (en) | 1983-12-28 |
| SU1039442A3 (ru) | 1983-08-30 |
| FI800588A7 (fi) | 1981-01-01 |
| JPS55141478A (en) | 1980-11-05 |
| ATE2219T1 (de) | 1983-01-15 |
| CS216525B2 (en) | 1982-11-26 |
| YU54680A (en) | 1983-09-30 |
| ES8106898A1 (es) | 1981-09-01 |
| ES495105A0 (es) | 1981-11-16 |
| IL59489A0 (en) | 1980-05-30 |
| ES495106A0 (es) | 1981-11-16 |
| DE3061561D1 (en) | 1983-02-17 |
| EP0015615A1 (en) | 1980-09-17 |
| AU5584880A (en) | 1980-09-04 |
| ES8200884A1 (es) | 1981-11-16 |
| ES8200883A1 (es) | 1981-11-16 |
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