PH12019502335A1 - Thermo-responsive gelling artificial lacrima - Google Patents

Thermo-responsive gelling artificial lacrima

Info

Publication number
PH12019502335A1
PH12019502335A1 PH12019502335A PH12019502335A PH12019502335A1 PH 12019502335 A1 PH12019502335 A1 PH 12019502335A1 PH 12019502335 A PH12019502335 A PH 12019502335A PH 12019502335 A PH12019502335 A PH 12019502335A PH 12019502335 A1 PH12019502335 A1 PH 12019502335A1
Authority
PH
Philippines
Prior art keywords
thermo
composition
present
responsive gelling
artificial lacrima
Prior art date
Application number
PH12019502335A
Other languages
English (en)
Inventor
Takeshi Yamamura
Ayaka YAMAMURO
Emi IZUKURA
Moto KIMURA
Tomohiro Otsuka
Original Assignee
Wakamoto Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakamoto Pharma Co Ltd filed Critical Wakamoto Pharma Co Ltd
Publication of PH12019502335A1 publication Critical patent/PH12019502335A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PH12019502335A 2017-04-25 2019-10-14 Thermo-responsive gelling artificial lacrima PH12019502335A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017086512 2017-04-25
JP2017249891 2017-12-26
PCT/JP2018/016854 WO2018199180A1 (ja) 2017-04-25 2018-04-25 熱ゲル化人工涙液

Publications (1)

Publication Number Publication Date
PH12019502335A1 true PH12019502335A1 (en) 2020-09-14

Family

ID=63919901

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12019502335A PH12019502335A1 (en) 2017-04-25 2019-10-14 Thermo-responsive gelling artificial lacrima

Country Status (16)

Country Link
US (2) US10532026B2 (https=)
EP (1) EP3593806B1 (https=)
JP (2) JP6473274B1 (https=)
KR (2) KR102281853B1 (https=)
CN (2) CN110913867B (https=)
AU (1) AU2018257301B2 (https=)
BR (1) BR112019018368B1 (https=)
CA (1) CA3025567C (https=)
ES (1) ES2912289T3 (https=)
MX (2) MX379302B (https=)
MY (2) MY196565A (https=)
PH (1) PH12019502335A1 (https=)
RU (1) RU2710366C1 (https=)
SG (1) SG11201909170QA (https=)
TW (1) TWI733019B (https=)
WO (1) WO2018199180A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117137866A (zh) * 2018-02-28 2023-12-01 参天制药株式会社 含有地夸磷索及阳离子性聚合物的眼科用组合物
AU2019228913C1 (en) * 2018-03-01 2024-10-31 Ishihara Sangyo Kaisha, Ltd. Pharmaceutical composition with excellent storage stability
ES2994624T3 (en) * 2019-02-27 2025-01-27 Santen Pharmaceutical Co Ltd Ophthalmic composition containing diquafosol or salt thereof, vinyl-based polymer and cellulose-based polymer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2125060C (en) * 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
JP3450805B2 (ja) 2000-08-08 2003-09-29 わかもと製薬株式会社 水性医薬組成物
JP2003095924A (ja) * 2001-07-16 2003-04-03 Wakamoto Pharmaceut Co Ltd 熱ゲル化人工涙液
GB0210794D0 (en) * 2002-05-10 2002-06-19 Chart Heat Exchangers Ltd Heat exchangers
JP4263456B2 (ja) 2002-03-18 2009-05-13 わかもと製薬株式会社 ヒアルロン酸含有熱ゲル化製剤
JP4263418B2 (ja) * 2002-03-18 2009-05-13 わかもと製薬株式会社 熱ゲル化人工涙液
JP4947977B2 (ja) 2003-10-31 2012-06-06 わかもと製薬株式会社 可逆性熱ゲル化水性組成物
JP5649261B2 (ja) * 2004-05-07 2015-01-07 ロート製薬株式会社 高粘度点眼剤
JP5661981B2 (ja) * 2004-11-26 2015-01-28 大正製薬株式会社 眼科用剤
EP2172224A4 (en) * 2007-06-26 2013-01-16 Wakamoto Pharma Co Ltd AQUEOUS COMPOSITION

Also Published As

Publication number Publication date
JP2019104740A (ja) 2019-06-27
AU2018257301B2 (en) 2019-10-31
CN110913867B (zh) 2021-06-11
CN113332233A (zh) 2021-09-03
TW201842900A (zh) 2018-12-16
KR102281853B1 (ko) 2021-07-23
EP3593806B1 (en) 2022-03-30
MX2018014935A (es) 2019-04-09
MX379302B (es) 2025-03-11
BR112019018368A2 (pt) 2020-04-07
TWI733019B (zh) 2021-07-11
KR20190110624A (ko) 2019-09-30
AU2018257301A1 (en) 2019-08-22
JP6736705B2 (ja) 2020-08-05
WO2018199180A1 (ja) 2018-11-01
MY196323A (en) 2023-03-24
EP3593806A1 (en) 2020-01-15
US20200121592A1 (en) 2020-04-23
CA3025567C (en) 2019-10-22
CA3025567A1 (en) 2018-11-01
JPWO2018199180A1 (ja) 2019-06-27
CN113332233B (zh) 2022-02-25
US10532026B2 (en) 2020-01-14
RU2710366C1 (ru) 2019-12-26
US11096889B2 (en) 2021-08-24
SG11201909170QA (en) 2019-11-28
ES2912289T3 (es) 2022-05-25
KR20200020999A (ko) 2020-02-26
BR112019018368B1 (pt) 2021-03-02
EP3593806A4 (en) 2020-03-25
KR102083253B1 (ko) 2020-03-02
MY196565A (en) 2023-04-19
US20180360746A1 (en) 2018-12-20
JP6473274B1 (ja) 2019-02-20
CN110913867A (zh) 2020-03-24

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