MX2017015835A - Gel oftalmico de bimatoprost aplicable en gotas. - Google Patents
Gel oftalmico de bimatoprost aplicable en gotas.Info
- Publication number
- MX2017015835A MX2017015835A MX2017015835A MX2017015835A MX2017015835A MX 2017015835 A MX2017015835 A MX 2017015835A MX 2017015835 A MX2017015835 A MX 2017015835A MX 2017015835 A MX2017015835 A MX 2017015835A MX 2017015835 A MX2017015835 A MX 2017015835A
- Authority
- MX
- Mexico
- Prior art keywords
- amount
- weight
- gel
- viscosity
- drippable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
La invención se refiere a un gel oftálmico aplicable en gotas, en donde dicho gel tiene una composición que comprende bimatoprost en una cantidad deI 0.003 al 0.03 por ciento en peso, poliacrilato en una cantidad de > 0.2 por ciento en peso, povidona (PVP), dextrano, polietilenglicoles (PEG), carboxi-metil-celulosa (CMC) o poli-(alcohol vinílico) (PVA), en una cantidad del 0.2 al 10 por ciento en peso, un agente isotonizante en una cantidad para producir una osmolalidad de 200 a 400 miliosmoles/kilogramo, una sal para ajustar la viscosidad en una cantidad del 0.05 al 0.4 por ciento en peso, una base en una cantidad para ajustar el pH de 6 a 8, y los excipientes normalmente utilizados en los geles oftálmicos, y que tiene una viscosidad en el intervalo de 200 a 2,000 mPa*s.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15171233.8A EP3103439B1 (en) | 2015-06-09 | 2015-06-09 | Drippable ophthalmic bimatoprost gel |
PCT/EP2016/062990 WO2016198434A1 (en) | 2015-06-09 | 2016-06-08 | Drippable ophthalmic bimatoprost gel |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017015835A true MX2017015835A (es) | 2018-08-15 |
Family
ID=53298285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017015835A MX2017015835A (es) | 2015-06-09 | 2016-06-08 | Gel oftalmico de bimatoprost aplicable en gotas. |
Country Status (28)
Country | Link |
---|---|
US (1) | US10314780B2 (es) |
EP (2) | EP3103439B1 (es) |
JP (1) | JP6342087B1 (es) |
KR (1) | KR101889878B1 (es) |
CN (1) | CN107771074B (es) |
AU (1) | AU2016277336B2 (es) |
BR (1) | BR112017026552B1 (es) |
CA (1) | CA2985897C (es) |
CY (1) | CY1120883T1 (es) |
DK (1) | DK3307241T3 (es) |
ES (2) | ES2747302T3 (es) |
HK (1) | HK1247118A1 (es) |
HR (1) | HRP20181840T1 (es) |
IL (1) | IL256071B (es) |
LT (1) | LT3307241T (es) |
MA (1) | MA42290B1 (es) |
MX (1) | MX2017015835A (es) |
PL (2) | PL3103439T3 (es) |
PT (1) | PT3307241T (es) |
RS (1) | RS57948B1 (es) |
RU (1) | RU2698456C2 (es) |
SA (1) | SA517390480B1 (es) |
SG (1) | SG11201708642VA (es) |
SI (1) | SI3307241T1 (es) |
TN (1) | TN2017000445A1 (es) |
TR (1) | TR201815791T4 (es) |
UA (1) | UA121139C2 (es) |
WO (1) | WO2016198434A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3810082A1 (en) * | 2018-06-19 | 2021-04-28 | Cella Therapeutics, LLC | Sustained-release drug delivery systems comprising an intraocular pressure lowering agent, a cnp compound, an npr-b compound, a tie-2 agonist, or neurotrophic agent for use for treating glaucoma or ocular hypertension |
CN110200904B (zh) * | 2019-05-27 | 2021-07-23 | 上海昊海生物科技股份有限公司 | 一种降眼压缓释滴眼组合物及其制备方法 |
US11400100B2 (en) | 2019-12-11 | 2022-08-02 | Somerset Therapeutics, Llc. | Effective benzalkonium chloride-free bimatoprost ophthalmic compositions |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4209722C3 (de) | 1992-03-25 | 1997-06-19 | Medproject Pharma Entwicklungs | Tropfbares Gel für die Augenheilkunde |
DE10132876A1 (de) * | 2001-07-06 | 2003-01-30 | Medproject Pharma Entwicklungs | Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge |
GB0501192D0 (en) * | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
US7851504B2 (en) | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
FR2918891B1 (fr) | 2007-07-20 | 2009-09-25 | Thea Sa Lab | Solution ophtalmique a base de prostaglandines sans conservateur |
EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
FR2961694B1 (fr) * | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
US20130245124A1 (en) | 2010-07-29 | 2013-09-19 | Allergan, Inc. | Preservative free bimatoprost solutions |
WO2012163827A2 (en) * | 2011-05-27 | 2012-12-06 | Ratiopharm Gmbh | Ophthalmic preparation comprising a pgf2alpha analogue |
AU2012283895A1 (en) * | 2011-07-20 | 2014-02-06 | Allergan, Inc. | Fixed dose combination of bimatoprost and brimonidine |
CN104288092A (zh) * | 2013-07-16 | 2015-01-21 | 广东东阳光药业有限公司 | 拉坦前列素滴眼剂 |
CN104622798B (zh) * | 2014-12-05 | 2017-12-22 | 广东东阳光药业有限公司 | 一种含有他氟前列素的滴眼液及其制备方法 |
-
2015
- 2015-06-09 ES ES15171233T patent/ES2747302T3/es active Active
- 2015-06-09 EP EP15171233.8A patent/EP3103439B1/en active Active
- 2015-06-09 PL PL15171233T patent/PL3103439T3/pl unknown
-
2016
- 2016-06-08 RS RS20181341A patent/RS57948B1/sr unknown
- 2016-06-08 TR TR2018/15791T patent/TR201815791T4/tr unknown
- 2016-06-08 MA MA42290A patent/MA42290B1/fr unknown
- 2016-06-08 CA CA2985897A patent/CA2985897C/en active Active
- 2016-06-08 TN TNP/2017/000445A patent/TN2017000445A1/en unknown
- 2016-06-08 MX MX2017015835A patent/MX2017015835A/es active IP Right Grant
- 2016-06-08 WO PCT/EP2016/062990 patent/WO2016198434A1/en active Application Filing
- 2016-06-08 SG SG11201708642VA patent/SG11201708642VA/en unknown
- 2016-06-08 CN CN201680033806.8A patent/CN107771074B/zh active Active
- 2016-06-08 US US15/580,770 patent/US10314780B2/en active Active
- 2016-06-08 ES ES16729525T patent/ES2703432T3/es active Active
- 2016-06-08 RU RU2017138099A patent/RU2698456C2/ru active
- 2016-06-08 EP EP16729525.2A patent/EP3307241B8/en active Active
- 2016-06-08 BR BR112017026552-4A patent/BR112017026552B1/pt active IP Right Grant
- 2016-06-08 AU AU2016277336A patent/AU2016277336B2/en active Active
- 2016-06-08 PT PT16729525T patent/PT3307241T/pt unknown
- 2016-06-08 DK DK16729525.2T patent/DK3307241T3/en active
- 2016-06-08 UA UAA201800181A patent/UA121139C2/uk unknown
- 2016-06-08 SI SI201630107T patent/SI3307241T1/sl unknown
- 2016-06-08 PL PL16729525T patent/PL3307241T3/pl unknown
- 2016-06-08 KR KR1020177033703A patent/KR101889878B1/ko active IP Right Grant
- 2016-06-08 LT LTEP16729525.2T patent/LT3307241T/lt unknown
- 2016-06-08 JP JP2017557200A patent/JP6342087B1/ja active Active
-
2017
- 2017-12-03 IL IL256071A patent/IL256071B/en active IP Right Grant
- 2017-12-05 SA SA517390480A patent/SA517390480B1/ar unknown
-
2018
- 2018-05-25 HK HK18106817.8A patent/HK1247118A1/zh unknown
- 2018-11-06 HR HRP20181840TT patent/HRP20181840T1/hr unknown
- 2018-11-20 CY CY181101224T patent/CY1120883T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12018500284A1 (en) | 5-bromo-2,6-di-(1h-pyrazol-1-yl)pyrimidin-4-amine for use in the treatment of cancer | |
MY197845A (en) | Pharmaceutical composition | |
MX2023003124A (es) | Composiciones farmaceuticas oftalmicas y usos que se relacionan a las mismas. | |
MX2017015105A (es) | Compuestos del peptido yy (pyy) selectivos y sus usos. | |
IT1393402B1 (it) | Uso di enhancer eventualmente con riboflavina, nonche' relative composizioni oftalmiche per cross-linking corneale del cheratocono o di altre patologie ectasiche corneali | |
MX2022011896A (es) | Composiciones oftalmicas. | |
MX2015012414A (es) | Sal de omecamtiv mecarbilo y proceso para preparar la sal. | |
MX2020009857A (es) | Conjugados de interleucina-2 (il-2). | |
PH12017501539A1 (en) | Disacetoxytubulysin h and analogs thereof | |
PH12019501639A1 (en) | Jaki selective inhibitors | |
MX2017015835A (es) | Gel oftalmico de bimatoprost aplicable en gotas. | |
IN2013MU03583A (es) | ||
PH12020550608A1 (en) | Pyrrole derivatives as acc inhibitors | |
GB202202470D0 (en) | Bio-ink formulations, bio-printed corneal lenticule, and applications thereof | |
EP3412292A4 (en) | USE OF METHOXATIN, DERIVATIVE AND / OR SALT OF SJÖGREN SYNDROME AND PHARMACEUTICAL COMPOSITION | |
WO2017223261A3 (en) | Hydrogels, articles comprising hydrogels, and methods thereof | |
CR20200275A (es) | Hidroxiisoxazolinas y derivados de estos | |
TR201713929A2 (tr) | Ki̇tosan ve alji̇natin hemostati̇k kompozi̇syonlari | |
PH12020550009A1 (en) | Pharmaceutical preparation and preparation method therefor | |
MX2023011670A (es) | Formulacion estable de anticuerpo contra el receptor de oncostatina m (osmr). | |
MX2018008868A (es) | Composiciones farmaceuticas que contienen glucomanano con liberacion extendida y propiedades disuasivas de abuso. | |
WO2015081319A3 (en) | Activity enhancing curcumin compositions and methods of use | |
MX2017002194A (es) | Composicion anticorrosion. | |
WO2012147101A3 (en) | Pharmaceutical compositions of raltegravir, methods of preparation and use thereof | |
EP3257881A4 (en) | Fluorinated copolymer, and surface modifier containing same as active ingredient |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |