MX2018014935A - Lagrima artificial de gelificacion termo-responsiva. - Google Patents
Lagrima artificial de gelificacion termo-responsiva.Info
- Publication number
- MX2018014935A MX2018014935A MX2018014935A MX2018014935A MX2018014935A MX 2018014935 A MX2018014935 A MX 2018014935A MX 2018014935 A MX2018014935 A MX 2018014935A MX 2018014935 A MX2018014935 A MX 2018014935A MX 2018014935 A MX2018014935 A MX 2018014935A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- artificial tears
- present
- temperature
- viscosity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
La presente invención es una solución acuosa que contiene dos tipos de metil celulosas, polietilenglicol, polivinilpirrolidona y ácido cítrico o una sal farmacéuticamente aceptable del mismo. La composición de la presente invención mantiene una baja viscosidad alrededor de la temperatura ambiente, pero la composición se incrementa repentinamente en la viscosidad debido al calor alrededor de la temperatura del cuerpo y tiene tixotropía aún después de la gelificación.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2017086512 | 2017-04-25 | ||
JP2017249891 | 2017-12-26 | ||
PCT/JP2018/016854 WO2018199180A1 (ja) | 2017-04-25 | 2018-04-25 | 熱ゲル化人工涙液 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018014935A true MX2018014935A (es) | 2019-04-09 |
Family
ID=63919901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018014935A MX2018014935A (es) | 2017-04-25 | 2018-04-25 | Lagrima artificial de gelificacion termo-responsiva. |
Country Status (16)
Country | Link |
---|---|
US (2) | US10532026B2 (es) |
EP (1) | EP3593806B1 (es) |
JP (2) | JP6473274B1 (es) |
KR (2) | KR102083253B1 (es) |
CN (2) | CN110913867B (es) |
AU (1) | AU2018257301B2 (es) |
BR (1) | BR112019018368B1 (es) |
CA (1) | CA3025567C (es) |
ES (1) | ES2912289T3 (es) |
MX (1) | MX2018014935A (es) |
MY (2) | MY196323A (es) |
PH (1) | PH12019502335A1 (es) |
RU (1) | RU2710366C1 (es) |
SG (1) | SG11201909170QA (es) |
TW (1) | TWI733019B (es) |
WO (1) | WO2018199180A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113518646B (zh) * | 2019-02-27 | 2023-12-12 | 参天制药株式会社 | 含有地夸磷索或其盐,乙烯基系高分子及纤维素系高分子的眼科用组合物 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2125060C (en) * | 1993-07-02 | 1999-03-30 | Henry P. Dabrowski | Ophthalmic solution for artificial tears |
JP3450805B2 (ja) * | 2000-08-08 | 2003-09-29 | わかもと製薬株式会社 | 水性医薬組成物 |
JP2003095924A (ja) * | 2001-07-16 | 2003-04-03 | Wakamoto Pharmaceut Co Ltd | 熱ゲル化人工涙液 |
GB0210794D0 (en) * | 2002-05-10 | 2002-06-19 | Chart Heat Exchangers Ltd | Heat exchangers |
JP4263418B2 (ja) * | 2002-03-18 | 2009-05-13 | わかもと製薬株式会社 | 熱ゲル化人工涙液 |
JP4263456B2 (ja) | 2002-03-18 | 2009-05-13 | わかもと製薬株式会社 | ヒアルロン酸含有熱ゲル化製剤 |
WO2005042026A1 (ja) | 2003-10-31 | 2005-05-12 | Wakamoto Pharmaceutical Co., Ltd. | 可逆性熱ゲル化水性組成物 |
JP5649261B2 (ja) * | 2004-05-07 | 2015-01-07 | ロート製薬株式会社 | 高粘度点眼剤 |
JP5661981B2 (ja) * | 2004-11-26 | 2015-01-28 | 大正製薬株式会社 | 眼科用剤 |
WO2009001899A1 (ja) * | 2007-06-26 | 2008-12-31 | Wakamoto Pharmaceutical Co., Ltd. | 水性組成物 |
-
2018
- 2018-04-25 CN CN201880026982.8A patent/CN110913867B/zh active Active
- 2018-04-25 MY MYPI2021001185A patent/MY196323A/en unknown
- 2018-04-25 MX MX2018014935A patent/MX2018014935A/es active IP Right Grant
- 2018-04-25 JP JP2018527825A patent/JP6473274B1/ja active Active
- 2018-04-25 CA CA3025567A patent/CA3025567C/en active Active
- 2018-04-25 ES ES18790126T patent/ES2912289T3/es active Active
- 2018-04-25 WO PCT/JP2018/016854 patent/WO2018199180A1/ja unknown
- 2018-04-25 BR BR112019018368-0A patent/BR112019018368B1/pt active IP Right Grant
- 2018-04-25 EP EP18790126.9A patent/EP3593806B1/en active Active
- 2018-04-25 AU AU2018257301A patent/AU2018257301B2/en not_active Ceased
- 2018-04-25 TW TW107114359A patent/TWI733019B/zh active
- 2018-04-25 KR KR1020197026971A patent/KR102083253B1/ko active IP Right Grant
- 2018-04-25 KR KR1020207004982A patent/KR102281853B1/ko active IP Right Grant
- 2018-04-25 RU RU2019123442A patent/RU2710366C1/ru active
- 2018-04-25 SG SG11201909170Q patent/SG11201909170QA/en unknown
- 2018-04-25 CN CN202110681026.7A patent/CN113332233B/zh active Active
- 2018-04-25 MY MYPI2019006324A patent/MY196565A/en unknown
- 2018-08-23 US US16/110,056 patent/US10532026B2/en active Active
-
2019
- 2019-01-24 JP JP2019010213A patent/JP6736705B2/ja active Active
- 2019-10-14 PH PH12019502335A patent/PH12019502335A1/en unknown
- 2019-12-17 US US16/717,004 patent/US11096889B2/en active Active
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |