PH12016501699A1 - 1,2-dihydro-3h-pyrrolo[1,2-c]imidazol-3-one derivatives and their use as antibacterial agents - Google Patents
1,2-dihydro-3h-pyrrolo[1,2-c]imidazol-3-one derivatives and their use as antibacterial agentsInfo
- Publication number
- PH12016501699A1 PH12016501699A1 PH12016501699A PH12016501699A PH12016501699A1 PH 12016501699 A1 PH12016501699 A1 PH 12016501699A1 PH 12016501699 A PH12016501699 A PH 12016501699A PH 12016501699 A PH12016501699 A PH 12016501699A PH 12016501699 A1 PH12016501699 A1 PH 12016501699A1
- Authority
- PH
- Philippines
- Prior art keywords
- pyrrolo
- imidazol
- dihydro
- derivatives
- antibacterial agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14157636 | 2014-03-04 | ||
| PCT/EP2015/054358 WO2015132228A1 (en) | 2014-03-04 | 2015-03-03 | 1,2-dihydro-3h-pyrrolo[1,2-c]imidazol-3-one derivatives and their use as antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12016501699A1 true PH12016501699A1 (en) | 2016-10-03 |
Family
ID=50189621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12016501699A PH12016501699A1 (en) | 2014-03-04 | 2016-08-26 | 1,2-dihydro-3h-pyrrolo[1,2-c]imidazol-3-one derivatives and their use as antibacterial agents |
Country Status (31)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| ES2666130T3 (es) | 2013-12-19 | 2018-05-03 | Idorsia Pharmaceuticals Ltd | Derivados antibacterianos de 1H-indazol y 1H-indol |
| KR20170005105A (ko) | 2014-05-16 | 2017-01-11 | 액테리온 파마슈티칼 리미티드 | 항균성 퀴나졸린-４(３ｈ)-온 유도체 |
| AR105646A1 (es) * | 2015-08-11 | 2017-10-25 | Actelion Pharmaceuticals Ltd | Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida |
| US20190031676A1 (en) * | 2015-08-28 | 2019-01-31 | Idorsia Pharmaceuticals Ltd | Antibacterial annulated pyrrolidin-2-one derivatives |
| AR105848A1 (es) * | 2015-08-31 | 2017-11-15 | Actelion Pharmaceuticals Ltd | Derivados heterocíclicos antibacterianos |
| AR105889A1 (es) * | 2015-09-03 | 2017-11-22 | Actelion Pharmaceuticals Ltd | Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos |
| TW201840569A (zh) | 2017-03-01 | 2018-11-16 | 瑞士商愛杜西亞製藥有限公司 | (2r)-n-羥基-4-(6-((1-(2-羥基乙基)氮雜環丁烷-3-基)丁-1,3-二炔-1-基)-3-氧基-1h-吡咯并[1,2-c]咪唑-2(3h)-基)-2-甲基-2-(甲磺醯基)丁醯胺之結晶形式 |
| WO2019038362A1 (en) | 2017-08-24 | 2019-02-28 | Idorsia Pharmaceuticals Ltd | ANTIBACTERIAL PYRROLOIMIDAZOLONES |
| WO2019086452A1 (en) | 2017-10-31 | 2019-05-09 | Idorsia Pharmaceuticals Ltd | Antibacterial heteroaromatic compounds |
| CN117769548A (zh) * | 2021-08-05 | 2024-03-26 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和用途 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL401638A1 (pl) | 2002-03-13 | 2013-05-27 | Array Biopharma Inc. | N3 alkilowane pochodne benzimidazolu jako inhibitory MEK |
| US7781591B2 (en) | 2006-06-13 | 2010-08-24 | Wyeth Llc | Substituted 3-cyanopyridines as protein kinase inhibitors |
| DE102004017930A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| JP2008523098A (ja) | 2004-12-10 | 2008-07-03 | エモリー・ユニバーシテイ | ウィルス感染および異常細胞増殖の治療用の２′および３′−置換シクロブチルヌクレオシド類縁体 |
| JP2008001635A (ja) | 2006-06-22 | 2008-01-10 | Toray Ind Inc | グリシン誘導体及びその用途 |
| DE102008044132A1 (de) | 2008-11-27 | 2010-06-02 | BSH Bosch und Siemens Hausgeräte GmbH | Kältegerät mit zweiseitig anschlagbarer Tür |
| ES2444443T3 (es) | 2009-04-06 | 2014-02-25 | Daiichi Sankyo Company, Limited | Compuesto cíclico que tiene un grupo fenilo sustituido |
| WO2010135536A2 (en) | 2009-05-20 | 2010-11-25 | Ardea Biosciences, Inc. | Methods of modulating uric acid levels |
| CN102548975A (zh) | 2009-07-07 | 2012-07-04 | 安瑟生物科技私人有限公司 | 组蛋白去乙酰化酶抑制剂 |
| EP2488489A2 (en) * | 2009-10-13 | 2012-08-22 | Pfizer Inc. | C-linked hydroxamic acid derivatives useful as antibacterial agents |
| CA2899583A1 (en) | 2009-12-16 | 2011-06-23 | Pfizer Inc. | N-linked hydroxamic acid derivatives useful as antibacterial agents |
| BR112013011693A2 (pt) | 2010-11-10 | 2016-08-09 | Achaogen Inc | derivados de ácido hidroxâmico e seu uso no tratamento de infecções por bactérias |
| JP2014501274A (ja) | 2011-01-03 | 2014-01-20 | ハンミ ファーム． シーオー．， エルティーディー． | Ｇタンパク質共役受容体調節のための新規な二環式化合物 |
| KR101593288B1 (ko) * | 2011-03-07 | 2016-02-11 | 화이자 인코포레이티드 | 항균제로서 유용한 플루오로-피리디논 유도체 |
| CN103492368A (zh) * | 2011-04-08 | 2014-01-01 | 辉瑞大药厂 | 用作抗菌剂的咪唑、吡唑和噻唑衍生物 |
| AU2012238374B2 (en) * | 2011-04-08 | 2015-04-02 | Pfizer Inc. | Isoxazole derivatives useful as antibacterial agents |
| US8859559B2 (en) | 2011-12-20 | 2014-10-14 | Boehringer Ingelheim International Gmbh | Substituted pyrazines and their use in the treatment of disease |
| WO2013170030A1 (en) | 2012-05-09 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2013170165A1 (en) | 2012-05-10 | 2013-11-14 | Achaogen, Inc. | Antibacterial agents |
| WO2014165075A1 (en) | 2013-03-12 | 2014-10-09 | Achaogen, Inc. | Antibacterial agents |
| AR097617A1 (es) | 2013-09-13 | 2016-04-06 | Actelion Pharmaceuticals Ltd | Derivados antibacterianos del 2h-indazol |
| ES2666130T3 (es) | 2013-12-19 | 2018-05-03 | Idorsia Pharmaceuticals Ltd | Derivados antibacterianos de 1H-indazol y 1H-indol |
| KR20170005105A (ko) | 2014-05-16 | 2017-01-11 | 액테리온 파마슈티칼 리미티드 | 항균성 퀴나졸린-４(３ｈ)-온 유도체 |
| AR105646A1 (es) | 2015-08-11 | 2017-10-25 | Actelion Pharmaceuticals Ltd | Agentes antibacterianos de 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituida |
| US20190031676A1 (en) | 2015-08-28 | 2019-01-31 | Idorsia Pharmaceuticals Ltd | Antibacterial annulated pyrrolidin-2-one derivatives |
| AR105848A1 (es) | 2015-08-31 | 2017-11-15 | Actelion Pharmaceuticals Ltd | Derivados heterocíclicos antibacterianos |
| AR105889A1 (es) | 2015-09-03 | 2017-11-22 | Actelion Pharmaceuticals Ltd | Compuestos antibacterianos 1,2-dihidro-3h-pirrolo[1,2-c]imidazol-3-ona sustituidos |
| AU2016367510A1 (en) | 2015-12-08 | 2018-06-07 | Glaxosmithkline Intellectual Property Development Limited | Substituted benzazinones as antibacterial compounds |
-
2015
- 2015-03-02 AR ARP150100626A patent/AR099612A1/es unknown
- 2015-03-03 CN CN201580011865.0A patent/CN106061977B/zh not_active Expired - Fee Related
- 2015-03-03 EP EP15707154.9A patent/EP3114126B1/en not_active Not-in-force
- 2015-03-03 JP JP2016555488A patent/JP6516370B2/ja not_active Expired - Fee Related
- 2015-03-03 AU AU2015226250A patent/AU2015226250B2/en not_active Ceased
- 2015-03-03 US US15/123,184 patent/US10106544B2/en not_active Expired - Fee Related
- 2015-03-03 LT LTEP15707154.9T patent/LT3114126T/lt unknown
- 2015-03-03 DK DK15707154.9T patent/DK3114126T3/en active
- 2015-03-03 UA UAA201609996A patent/UA118868C2/uk unknown
- 2015-03-03 PL PL15707154T patent/PL3114126T3/pl unknown
- 2015-03-03 KR KR1020167027128A patent/KR20160127127A/ko not_active Ceased
- 2015-03-03 SI SI201530520T patent/SI3114126T1/sl unknown
- 2015-03-03 HU HUE15707154A patent/HUE042371T2/hu unknown
- 2015-03-03 ES ES15707154T patent/ES2709382T3/es active Active
- 2015-03-03 MX MX2016011380A patent/MX2016011380A/es unknown
- 2015-03-03 WO PCT/EP2015/054358 patent/WO2015132228A1/en not_active Ceased
- 2015-03-03 TW TW104106737A patent/TW201542556A/zh unknown
- 2015-03-03 BR BR112016020278A patent/BR112016020278A8/pt not_active Application Discontinuation
- 2015-03-03 TR TR2019/00393T patent/TR201900393T4/tr unknown
- 2015-03-03 SG SG11201607304WA patent/SG11201607304WA/en unknown
- 2015-03-03 CA CA2938383A patent/CA2938383A1/en not_active Abandoned
- 2015-03-03 EA EA201691775A patent/EA030708B1/ru not_active IP Right Cessation
- 2015-03-03 PT PT15707154T patent/PT3114126T/pt unknown
- 2015-03-03 MA MA39707A patent/MA39707B1/fr unknown
- 2015-03-03 HR HRP20190013TT patent/HRP20190013T1/hr unknown
-
2016
- 2016-08-23 SA SA516371717A patent/SA516371717B1/ar unknown
- 2016-08-26 PH PH12016501699A patent/PH12016501699A1/en unknown
- 2016-08-30 IL IL247544A patent/IL247544A0/en unknown
- 2016-09-01 CL CL2016002207A patent/CL2016002207A1/es unknown
- 2016-10-03 ZA ZA2016/06794A patent/ZA201606794B/en unknown
-
2019
- 2019-01-30 CY CY20191100131T patent/CY1121362T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12016501699A1 (en) | 1,2-dihydro-3h-pyrrolo[1,2-c]imidazol-3-one derivatives and their use as antibacterial agents | |
| UY36544A (es) | Derivados de 4h-pirrol[3,2-c]piridin-4-ona | |
| PH12015501934B1 (en) | New octahydro - pyrrolo [3,4-c] - pyrrole derivatives and analogs thereof as autotaxin inhibitors | |
| WO2016011390A8 (en) | Irak4 inhibiting agents | |
| MX392230B (es) | Pirimidina-2-ilamino-1h-pirazoles como inhibidores de lrrk2 para el uso en el tratamiento de trastornos neurogenerativos. | |
| MY179283A (en) | Antibacterial 2h-indazole derivatives | |
| PH12014501719A1 (en) | Pyridone derivatives | |
| EA201692219A1 (ru) | Способы получения противовирусных соединений | |
| PH12016500643A1 (en) | New octahydro - cyclobuta [1,2-c;3,4-c`] dipyrrol -2- yl | |
| SG10201805628TA (en) | Deuterated heterocyclic compounds and their use as imaging agents | |
| CO2017012994A2 (es) | Compuestos tricíclicos y su uso como inhibidores de la fosfodiesterasa | |
| MY194307A (en) | Pyridone derivative having tetrahydropyranylmethyl group | |
| EA201790627A1 (ru) | СТИМУЛЯТОРЫ рГЦ | |
| BR112016029825A2 (pt) | composto | |
| UY33993A (es) | Análogo macrocíclico de la sangliferina y su método de producción | |
| EA201790016A1 (ru) | АНАЛОГ ПИРИДИНО[1,2-a]ПИРИМИДОНА, ПРИМЕНЯЕМЫЙ В КАЧЕСТВЕ ИНГИБИТОРА PI3K | |
| PH12016501349A1 (en) | Hydroxy formamide derivatives and their use | |
| EA201890476A1 (ru) | ЗАМЕЩЕННЫЕ 1,2-ДИГИДРО-3H-ПИРРОЛО[1,2-c]ИМИДАЗОЛ-3-ОНЫ В КАЧЕСТВЕ АНТИБАКТЕРИАЛЬНЫХ СРЕДСТВ | |
| JOP20190163A1 (ar) | منشط nrf2 | |
| AR092772A1 (es) | Derivado de 7-azaindol | |
| MX2018014170A (es) | Derivados 6-(buta-1,3-diin-1-il)benzo[d]tiazol. | |
| MX373441B (es) | Derivados de indol-urea glucopiranosil-sustituido y su uso como inhibidores sglt. | |
| CA3006413C (en) | Benzo[b][1,6]naphthyridine derivatives as VPPC-tubulin inhibitors | |
| EA201700037A1 (ru) | Производные 2н-хромена в качестве анальгезирующих средств | |
| UA79866U (ru) | Применение 2-оксоиндолин-3-глиоксиловой кислоты в качестве средств с антидепрессивным действием |