PH12014500694B1 - Glycosylated polypeptide and pharmaceutical composition containing same - Google Patents
Glycosylated polypeptide and pharmaceutical composition containing sameInfo
- Publication number
- PH12014500694B1 PH12014500694B1 PH1/2014/500694A PH12014500694A PH12014500694B1 PH 12014500694 B1 PH12014500694 B1 PH 12014500694B1 PH 12014500694 A PH12014500694 A PH 12014500694A PH 12014500694 B1 PH12014500694 B1 PH 12014500694B1
- Authority
- PH
- Philippines
- Prior art keywords
- glycosylated polypeptide
- pharmaceutical composition
- composition containing
- containing same
- glycosylated
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000007079 Peptide Fragments Human genes 0.000 abstract 4
- 108010033276 Peptide Fragments Proteins 0.000 abstract 4
- 102000014150 Interferons Human genes 0.000 abstract 2
- 108010050904 Interferons Proteins 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229940079322 interferon Drugs 0.000 abstract 2
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011218793 | 2011-10-01 | ||
| PCT/JP2012/075262 WO2013047846A1 (ja) | 2011-10-01 | 2012-09-28 | 糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12014500694A1 PH12014500694A1 (en) | 2014-05-12 |
| PH12014500694B1 true PH12014500694B1 (en) | 2020-01-31 |
Family
ID=47995870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2014/500694A PH12014500694B1 (en) | 2011-10-01 | 2012-09-28 | Glycosylated polypeptide and pharmaceutical composition containing same |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10358470B2 (enExample) |
| EP (1) | EP2762489B1 (enExample) |
| JP (1) | JP6153470B2 (enExample) |
| KR (1) | KR101979045B1 (enExample) |
| CN (2) | CN104080803B (enExample) |
| AU (1) | AU2012317325B2 (enExample) |
| BR (1) | BR112014007766B1 (enExample) |
| CA (1) | CA2850469C (enExample) |
| DK (1) | DK2762489T3 (enExample) |
| IN (1) | IN2014CN02982A (enExample) |
| MY (1) | MY168902A (enExample) |
| PH (1) | PH12014500694B1 (enExample) |
| RU (1) | RU2636456C2 (enExample) |
| SG (2) | SG11201401071YA (enExample) |
| TW (1) | TWI633115B (enExample) |
| WO (1) | WO2013047846A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101979045B1 (ko) | 2011-10-01 | 2019-05-15 | 가부시키가이샤 도우사 고가쿠 겐큐쇼 | 당쇄 부가 폴리펩티드 및 상기 폴리펩티드를 포함하는 의약 조성물 |
| DK2982686T3 (en) | 2013-03-29 | 2018-10-08 | Glytech Inc | POLYPEPTIDE WITH SIALYLED SUGAR CHAIN CONNECTED |
| CN114685645B (zh) * | 2020-12-30 | 2025-03-21 | 深圳翰宇药业股份有限公司 | 一种索玛鲁肽的合成方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0237019A3 (en) * | 1986-03-14 | 1988-03-09 | Toray Industries, Inc. | Interferon conjugate and production thereof using recombinant gene |
| ES2218806T3 (es) | 1997-01-16 | 2004-11-16 | Neose Technologies, Inc. | Sialilacion practica in vitro de glicoproteinas recombinantes. |
| DE19717864C2 (de) | 1997-04-23 | 2001-05-17 | Fraunhofer Ges Forschung | Humanes rekombinantes Interferon-beta, Verfahren zu seiner Herstellung und seine Verwendung |
| BR9910023A (pt) * | 1998-04-28 | 2000-12-26 | Applied Research Systems | Conjugados de poliol-ifn-beta |
| EE05111B1 (et) * | 1998-10-16 | 2008-12-15 | Biogen, Incorporated | Interferoon-beetaga sulandatud valgud ja nende kasutamine |
| HU229888B1 (en) | 1998-10-16 | 2014-11-28 | Biogen Idec Ma Inc Cambridge | Polymer conjugates of interferon betha-1a and uses |
| US6514729B1 (en) | 1999-05-12 | 2003-02-04 | Xencor, Inc. | Recombinant interferon-beta muteins |
| DE60037978T2 (de) * | 1999-12-08 | 2008-05-21 | Amgen Inc., Thousand Oaks | Interferon ähnliche moleküle, und deren verwendungen |
| US7795002B2 (en) * | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| AU2001273385B2 (en) | 2000-09-08 | 2005-04-07 | Gryphon Therapeutics, Inc. | Polymer-modified synthetic proteins |
| JP2004534523A (ja) | 2001-02-27 | 2004-11-18 | マキシゲン・エイピーエス | 新規なインターフェロンβ様分子 |
| CA2441095A1 (en) | 2001-03-15 | 2002-09-26 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Modified interferon beta with reduced immunogenicity |
| US7226903B2 (en) * | 2001-10-10 | 2007-06-05 | Neose Technologies, Inc. | Interferon beta: remodeling and glycoconjugation of interferon beta |
| EP2305312B1 (en) * | 2001-10-10 | 2015-03-04 | ratiopharm GmbH | Remodelling and glycoconjugation of follicle-stimulating hormone (FSH) |
| CA2469487A1 (en) | 2001-12-11 | 2003-07-03 | Aventis Pasteur | Mutated hiv tat |
| MXPA04008798A (es) | 2002-03-12 | 2004-11-26 | Maxygen Aps | Moleculas semejantes a interferon beta para el tratamiento de evento cerebrovascular. |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| AU2003254641A1 (en) | 2002-08-28 | 2004-03-19 | Maxygen Aps | Interferon beta-like molecules for treatment of cancer |
| PL377612A1 (pl) * | 2002-09-27 | 2006-02-06 | Biogen Idec Ma Inc. | Terapie przewlekłej zapalnej polineuropatii demielinizacyjnej z użyciem interferonu-ß |
| AU2003277088A1 (en) | 2002-10-01 | 2004-04-23 | Xencor, Inc | Interferon variants with improved properties |
| AU2003292792A1 (en) | 2002-12-26 | 2004-07-22 | Kajihara, Yasuhiro | Sugar-chain asparagine derivatives and processes for the preparation thereof |
| EP1666496B1 (en) | 2003-08-25 | 2014-03-12 | Toray Industries, Inc. | Interferon-beta composite |
| JP2007526317A (ja) | 2004-03-01 | 2007-09-13 | エンゾン ファーマスーティカルズ インコーポレイテッド | インターフェロン−ベータ・ポリマー結合体 |
| EP1789074A4 (en) | 2004-08-09 | 2009-08-12 | Alios Biopharma Inc | PROTEASE-RESISTANT HYPERGLYCOSYL SYNTHETIC POLYPEPTIDE VARIANTS, ORAL FORMULATIONS AND METHODS OF USING THE SAME |
| RU2392963C2 (ru) * | 2004-08-09 | 2010-06-27 | Элиоз Байофарма, Инк. | Синтетические варианты гипергликозилированного протеазо-резистентного полипептида, пероральные композиции и способы применения таких вариантов |
| KR100781666B1 (ko) | 2004-11-02 | 2007-12-03 | 신영기 | 인간 인터페론-베타 변이체 |
| SG155183A1 (en) * | 2005-08-26 | 2009-09-30 | Ares Trading Sa | Process for the preparation of glycosylated interferon beta |
| WO2007110231A2 (en) * | 2006-03-28 | 2007-10-04 | Nautilus Biotech, S.A. | MODIFIED INTERFERON-β (IFN-β) POLYPEPTIDES |
| US20080096819A1 (en) | 2006-05-02 | 2008-04-24 | Allozyne, Inc. | Amino acid substituted molecules |
| TWI423821B (zh) | 2007-06-19 | 2014-01-21 | Glucose-containing glucagon-like peptide-1 peptide | |
| AU2008283317B2 (en) | 2007-07-31 | 2012-08-02 | Glytech, Inc. | Method for producing peptide |
| JP2009242372A (ja) | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| JP5604297B2 (ja) | 2008-06-17 | 2014-10-08 | 株式会社糖鎖工学研究所 | 糖鎖付加ｇｌｐ−１ペプチド |
| CA2733362C (en) | 2008-08-08 | 2016-10-18 | Universiteit Gent | Cells producing glycoproteins having altered glycosylation patterns and methods and use thereof |
| KR20110067097A (ko) * | 2008-08-19 | 2011-06-21 | 오츠카 가가쿠 가부시키가이샤 | 당단백질의 제조방법 및 스크리닝 방법 |
| WO2012051615A1 (en) | 2010-10-15 | 2012-04-19 | Transgenrx, Inc. | Novel vectors for production of glycosylated interferon |
| SG193377A1 (en) | 2011-03-10 | 2013-10-30 | Glytech Inc | Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide |
| ES2774284T3 (es) | 2011-06-29 | 2020-07-20 | Kyowa Kirin Co Ltd | Método para purificar antitrombina |
| KR101979045B1 (ko) | 2011-10-01 | 2019-05-15 | 가부시키가이샤 도우사 고가쿠 겐큐쇼 | 당쇄 부가 폴리펩티드 및 상기 폴리펩티드를 포함하는 의약 조성물 |
-
2012
- 2012-09-28 KR KR1020147010631A patent/KR101979045B1/ko not_active Expired - Fee Related
- 2012-09-28 EP EP12836998.0A patent/EP2762489B1/en active Active
- 2012-09-28 DK DK12836998.0T patent/DK2762489T3/en active
- 2012-09-28 US US14/347,222 patent/US10358470B2/en active Active
- 2012-09-28 PH PH1/2014/500694A patent/PH12014500694B1/en unknown
- 2012-09-28 JP JP2013536471A patent/JP6153470B2/ja not_active Expired - Fee Related
- 2012-09-28 BR BR112014007766-5A patent/BR112014007766B1/pt not_active IP Right Cessation
- 2012-09-28 SG SG11201401071YA patent/SG11201401071YA/en unknown
- 2012-09-28 WO PCT/JP2012/075262 patent/WO2013047846A1/ja not_active Ceased
- 2012-09-28 CN CN201280058952.8A patent/CN104080803B/zh not_active Expired - Fee Related
- 2012-09-28 CN CN201811042210.1A patent/CN109134642A/zh active Pending
- 2012-09-28 CA CA2850469A patent/CA2850469C/en active Active
- 2012-09-28 RU RU2014116550A patent/RU2636456C2/ru active
- 2012-09-28 IN IN2982CHN2014 patent/IN2014CN02982A/en unknown
- 2012-09-28 MY MYPI2014000925A patent/MY168902A/en unknown
- 2012-09-28 SG SG10201602076QA patent/SG10201602076QA/en unknown
- 2012-09-28 AU AU2012317325A patent/AU2012317325B2/en not_active Ceased
- 2012-10-01 TW TW101136177A patent/TWI633115B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2762489A9 (en) | 2015-02-11 |
| SG10201602076QA (en) | 2016-04-28 |
| CA2850469C (en) | 2020-07-07 |
| CN104080803A (zh) | 2014-10-01 |
| US10358470B2 (en) | 2019-07-23 |
| RU2014116550A (ru) | 2015-10-27 |
| KR101979045B1 (ko) | 2019-05-15 |
| RU2636456C2 (ru) | 2017-11-23 |
| MY168902A (en) | 2018-12-04 |
| BR112014007766A2 (pt) | 2017-04-04 |
| DK2762489T3 (en) | 2018-07-02 |
| CN104080803B (zh) | 2020-08-04 |
| JP6153470B2 (ja) | 2017-06-28 |
| CN109134642A (zh) | 2019-01-04 |
| AU2012317325B2 (en) | 2016-10-06 |
| EP2762489B1 (en) | 2018-03-28 |
| EP2762489A1 (en) | 2014-08-06 |
| US20140369964A1 (en) | 2014-12-18 |
| EP2762489A4 (en) | 2015-05-06 |
| IN2014CN02982A (enExample) | 2015-07-03 |
| SG11201401071YA (en) | 2014-08-28 |
| CA2850469A1 (en) | 2013-04-04 |
| TW201321404A (zh) | 2013-06-01 |
| KR20140095051A (ko) | 2014-07-31 |
| BR112014007766B1 (pt) | 2022-05-10 |
| WO2013047846A1 (ja) | 2013-04-04 |
| TWI633115B (zh) | 2018-08-21 |
| JPWO2013047846A1 (ja) | 2015-03-30 |
| PH12014500694A1 (en) | 2014-05-12 |
| AU2012317325A1 (en) | 2014-04-17 |
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