IN2014CN02982A - - Google Patents
Info
- Publication number
- IN2014CN02982A IN2014CN02982A IN2982CHN2014A IN2014CN02982A IN 2014CN02982 A IN2014CN02982 A IN 2014CN02982A IN 2982CHN2014 A IN2982CHN2014 A IN 2982CHN2014A IN 2014CN02982 A IN2014CN02982 A IN 2014CN02982A
- Authority
- IN
- India
- Prior art keywords
- glycosylated
- interferon
- activity
- glycosylated polypeptide
- carbohydrate structure
- Prior art date
Links
- 102000007079 Peptide Fragments Human genes 0.000 abstract 4
- 108010033276 Peptide Fragments Proteins 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 102000003996 Interferon-beta Human genes 0.000 abstract 2
- 108090000467 Interferon-beta Proteins 0.000 abstract 2
- 125000000837 carbohydrate group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229960001388 interferon-beta Drugs 0.000 abstract 2
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011218793 | 2011-10-01 | ||
| PCT/JP2012/075262 WO2013047846A1 (ja) | 2011-10-01 | 2012-09-28 | 糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN02982A true IN2014CN02982A (enExample) | 2015-07-03 |
Family
ID=47995870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2982CHN2014 IN2014CN02982A (enExample) | 2011-10-01 | 2012-09-28 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10358470B2 (enExample) |
| EP (1) | EP2762489B1 (enExample) |
| JP (1) | JP6153470B2 (enExample) |
| KR (1) | KR101979045B1 (enExample) |
| CN (2) | CN104080803B (enExample) |
| AU (1) | AU2012317325B2 (enExample) |
| BR (1) | BR112014007766B1 (enExample) |
| CA (1) | CA2850469C (enExample) |
| DK (1) | DK2762489T3 (enExample) |
| IN (1) | IN2014CN02982A (enExample) |
| MY (1) | MY168902A (enExample) |
| PH (1) | PH12014500694B1 (enExample) |
| RU (1) | RU2636456C2 (enExample) |
| SG (2) | SG11201401071YA (enExample) |
| TW (1) | TWI633115B (enExample) |
| WO (1) | WO2013047846A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101979045B1 (ko) | 2011-10-01 | 2019-05-15 | 가부시키가이샤 도우사 고가쿠 겐큐쇼 | 당쇄 부가 폴리펩티드 및 상기 폴리펩티드를 포함하는 의약 조성물 |
| DK2982686T3 (en) | 2013-03-29 | 2018-10-08 | Glytech Inc | POLYPEPTIDE WITH SIALYLED SUGAR CHAIN CONNECTED |
| CN114685645B (zh) * | 2020-12-30 | 2025-03-21 | 深圳翰宇药业股份有限公司 | 一种索玛鲁肽的合成方法 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0237019A3 (en) * | 1986-03-14 | 1988-03-09 | Toray Industries, Inc. | Interferon conjugate and production thereof using recombinant gene |
| ES2218806T3 (es) | 1997-01-16 | 2004-11-16 | Neose Technologies, Inc. | Sialilacion practica in vitro de glicoproteinas recombinantes. |
| DE19717864C2 (de) | 1997-04-23 | 2001-05-17 | Fraunhofer Ges Forschung | Humanes rekombinantes Interferon-beta, Verfahren zu seiner Herstellung und seine Verwendung |
| BR9910023A (pt) * | 1998-04-28 | 2000-12-26 | Applied Research Systems | Conjugados de poliol-ifn-beta |
| EE05111B1 (et) * | 1998-10-16 | 2008-12-15 | Biogen, Incorporated | Interferoon-beetaga sulandatud valgud ja nende kasutamine |
| HU229888B1 (en) | 1998-10-16 | 2014-11-28 | Biogen Idec Ma Inc Cambridge | Polymer conjugates of interferon betha-1a and uses |
| US6514729B1 (en) | 1999-05-12 | 2003-02-04 | Xencor, Inc. | Recombinant interferon-beta muteins |
| DE60037978T2 (de) * | 1999-12-08 | 2008-05-21 | Amgen Inc., Thousand Oaks | Interferon ähnliche moleküle, und deren verwendungen |
| US7795002B2 (en) * | 2000-06-28 | 2010-09-14 | Glycofi, Inc. | Production of galactosylated glycoproteins in lower eukaryotes |
| AU2001273385B2 (en) | 2000-09-08 | 2005-04-07 | Gryphon Therapeutics, Inc. | Polymer-modified synthetic proteins |
| JP2004534523A (ja) | 2001-02-27 | 2004-11-18 | マキシゲン・エイピーエス | 新規なインターフェロンβ様分子 |
| CA2441095A1 (en) | 2001-03-15 | 2002-09-26 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Modified interferon beta with reduced immunogenicity |
| US7226903B2 (en) * | 2001-10-10 | 2007-06-05 | Neose Technologies, Inc. | Interferon beta: remodeling and glycoconjugation of interferon beta |
| EP2305312B1 (en) * | 2001-10-10 | 2015-03-04 | ratiopharm GmbH | Remodelling and glycoconjugation of follicle-stimulating hormone (FSH) |
| CA2469487A1 (en) | 2001-12-11 | 2003-07-03 | Aventis Pasteur | Mutated hiv tat |
| MXPA04008798A (es) | 2002-03-12 | 2004-11-26 | Maxygen Aps | Moleculas semejantes a interferon beta para el tratamiento de evento cerebrovascular. |
| US7943763B2 (en) | 2002-07-05 | 2011-05-17 | Otsuka Chemical Holdings Co., Ltd. | Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides |
| AU2003254641A1 (en) | 2002-08-28 | 2004-03-19 | Maxygen Aps | Interferon beta-like molecules for treatment of cancer |
| PL377612A1 (pl) * | 2002-09-27 | 2006-02-06 | Biogen Idec Ma Inc. | Terapie przewlekłej zapalnej polineuropatii demielinizacyjnej z użyciem interferonu-ß |
| AU2003277088A1 (en) | 2002-10-01 | 2004-04-23 | Xencor, Inc | Interferon variants with improved properties |
| AU2003292792A1 (en) | 2002-12-26 | 2004-07-22 | Kajihara, Yasuhiro | Sugar-chain asparagine derivatives and processes for the preparation thereof |
| EP1666496B1 (en) | 2003-08-25 | 2014-03-12 | Toray Industries, Inc. | Interferon-beta composite |
| JP2007526317A (ja) | 2004-03-01 | 2007-09-13 | エンゾン ファーマスーティカルズ インコーポレイテッド | インターフェロン−ベータ・ポリマー結合体 |
| EP1789074A4 (en) | 2004-08-09 | 2009-08-12 | Alios Biopharma Inc | PROTEASE-RESISTANT HYPERGLYCOSYL SYNTHETIC POLYPEPTIDE VARIANTS, ORAL FORMULATIONS AND METHODS OF USING THE SAME |
| RU2392963C2 (ru) * | 2004-08-09 | 2010-06-27 | Элиоз Байофарма, Инк. | Синтетические варианты гипергликозилированного протеазо-резистентного полипептида, пероральные композиции и способы применения таких вариантов |
| KR100781666B1 (ko) | 2004-11-02 | 2007-12-03 | 신영기 | 인간 인터페론-베타 변이체 |
| SG155183A1 (en) * | 2005-08-26 | 2009-09-30 | Ares Trading Sa | Process for the preparation of glycosylated interferon beta |
| WO2007110231A2 (en) * | 2006-03-28 | 2007-10-04 | Nautilus Biotech, S.A. | MODIFIED INTERFERON-β (IFN-β) POLYPEPTIDES |
| US20080096819A1 (en) | 2006-05-02 | 2008-04-24 | Allozyne, Inc. | Amino acid substituted molecules |
| TWI423821B (zh) | 2007-06-19 | 2014-01-21 | Glucose-containing glucagon-like peptide-1 peptide | |
| AU2008283317B2 (en) | 2007-07-31 | 2012-08-02 | Glytech, Inc. | Method for producing peptide |
| JP2009242372A (ja) | 2008-03-11 | 2009-10-22 | Yokohama City Univ | 均一な糖鎖構造を有するエリスロポエチン誘導体 |
| JP5604297B2 (ja) | 2008-06-17 | 2014-10-08 | 株式会社糖鎖工学研究所 | 糖鎖付加ｇｌｐ−１ペプチド |
| CA2733362C (en) | 2008-08-08 | 2016-10-18 | Universiteit Gent | Cells producing glycoproteins having altered glycosylation patterns and methods and use thereof |
| KR20110067097A (ko) * | 2008-08-19 | 2011-06-21 | 오츠카 가가쿠 가부시키가이샤 | 당단백질의 제조방법 및 스크리닝 방법 |
| WO2012051615A1 (en) | 2010-10-15 | 2012-04-19 | Transgenrx, Inc. | Novel vectors for production of glycosylated interferon |
| SG193377A1 (en) | 2011-03-10 | 2013-10-30 | Glytech Inc | Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide |
| ES2774284T3 (es) | 2011-06-29 | 2020-07-20 | Kyowa Kirin Co Ltd | Método para purificar antitrombina |
| KR101979045B1 (ko) | 2011-10-01 | 2019-05-15 | 가부시키가이샤 도우사 고가쿠 겐큐쇼 | 당쇄 부가 폴리펩티드 및 상기 폴리펩티드를 포함하는 의약 조성물 |
-
2012
- 2012-09-28 KR KR1020147010631A patent/KR101979045B1/ko not_active Expired - Fee Related
- 2012-09-28 EP EP12836998.0A patent/EP2762489B1/en active Active
- 2012-09-28 DK DK12836998.0T patent/DK2762489T3/en active
- 2012-09-28 US US14/347,222 patent/US10358470B2/en active Active
- 2012-09-28 PH PH1/2014/500694A patent/PH12014500694B1/en unknown
- 2012-09-28 JP JP2013536471A patent/JP6153470B2/ja not_active Expired - Fee Related
- 2012-09-28 BR BR112014007766-5A patent/BR112014007766B1/pt not_active IP Right Cessation
- 2012-09-28 SG SG11201401071YA patent/SG11201401071YA/en unknown
- 2012-09-28 WO PCT/JP2012/075262 patent/WO2013047846A1/ja not_active Ceased
- 2012-09-28 CN CN201280058952.8A patent/CN104080803B/zh not_active Expired - Fee Related
- 2012-09-28 CN CN201811042210.1A patent/CN109134642A/zh active Pending
- 2012-09-28 CA CA2850469A patent/CA2850469C/en active Active
- 2012-09-28 RU RU2014116550A patent/RU2636456C2/ru active
- 2012-09-28 IN IN2982CHN2014 patent/IN2014CN02982A/en unknown
- 2012-09-28 MY MYPI2014000925A patent/MY168902A/en unknown
- 2012-09-28 SG SG10201602076QA patent/SG10201602076QA/en unknown
- 2012-09-28 AU AU2012317325A patent/AU2012317325B2/en not_active Ceased
- 2012-10-01 TW TW101136177A patent/TWI633115B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2762489A9 (en) | 2015-02-11 |
| SG10201602076QA (en) | 2016-04-28 |
| CA2850469C (en) | 2020-07-07 |
| CN104080803A (zh) | 2014-10-01 |
| US10358470B2 (en) | 2019-07-23 |
| RU2014116550A (ru) | 2015-10-27 |
| KR101979045B1 (ko) | 2019-05-15 |
| RU2636456C2 (ru) | 2017-11-23 |
| MY168902A (en) | 2018-12-04 |
| BR112014007766A2 (pt) | 2017-04-04 |
| DK2762489T3 (en) | 2018-07-02 |
| CN104080803B (zh) | 2020-08-04 |
| JP6153470B2 (ja) | 2017-06-28 |
| CN109134642A (zh) | 2019-01-04 |
| AU2012317325B2 (en) | 2016-10-06 |
| EP2762489B1 (en) | 2018-03-28 |
| EP2762489A1 (en) | 2014-08-06 |
| US20140369964A1 (en) | 2014-12-18 |
| EP2762489A4 (en) | 2015-05-06 |
| SG11201401071YA (en) | 2014-08-28 |
| CA2850469A1 (en) | 2013-04-04 |
| TW201321404A (zh) | 2013-06-01 |
| KR20140095051A (ko) | 2014-07-31 |
| PH12014500694B1 (en) | 2020-01-31 |
| BR112014007766B1 (pt) | 2022-05-10 |
| WO2013047846A1 (ja) | 2013-04-04 |
| TWI633115B (zh) | 2018-08-21 |
| JPWO2013047846A1 (ja) | 2015-03-30 |
| PH12014500694A1 (en) | 2014-05-12 |
| AU2012317325A1 (en) | 2014-04-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2012068317A3 (en) | Methods for producing recombinant proteins | |
| SG10201805291TA (en) | Production of heterodimeric proteins | |
| MX367859B (es) | Metodos y materiales para la biosintesis de compuestos mogrosidos. | |
| EP2680111A4 (en) | SUBSTRATE HAVING TRANSPARENT ELECTRODE, PRODUCTION METHOD THEREFOR, AND TOUCH SCREEN | |
| WO2013096291A3 (en) | Modified polypeptides for bispecific antibody scaffolds | |
| PL2619016T3 (pl) | Sposób wytwarzania paneli i panel wytworzony tym sposobem | |
| MX357965B (es) | Composicion farmaceutica para el tratamiento y/o prevencion de cancer de vesicula biliar. | |
| MX340558B (es) | Anticuerpos biespecificos que comprenden fragmento fv estabilizado con disulfuro. | |
| PH12013500336A1 (en) | Peptide or peptide complex binding to alpha2 integrin and methods and uses involving the same | |
| EP4477668A3 (en) | Heterodimeric antibody fc-containing proteins and methods for production thereof | |
| MY160680A (en) | Process for producing molecules containing specialized glycan structures | |
| ZA201100656B (en) | Method for producing panels and panel produced according to the method | |
| MX2014015768A (es) | Microorganismo recombinante para la produccion fermentativa de metionina. | |
| EP2677029A3 (en) | Methods for the manufacture of proteolytically processed polypeptides | |
| WO2009049284A3 (en) | Compositions and methods for improved glycoprotein sialylation | |
| IN2014MN01331A (enExample) | ||
| WO2015021058A3 (en) | Engineered proteins with a protease cleavage site | |
| MY181068A (en) | Recombinant microorganism for improved production of fine chemicals | |
| SG11201402586YA (en) | Mutant xylanase, manufacturing method and use therefor, and method for manufacturing saccharified lignocellulose | |
| MX2011012623A (es) | Construcciones de casb7439. | |
| MX2014004083A (es) | Metodo para aislar ingenol. | |
| IN2014CN02982A (enExample) | ||
| EP2632857A4 (en) | METHOD AND SYSTEM FOR PREPARING ANOLYT FRACTION | |
| EP2876113A4 (en) | Method for producing a recombinant peptide and resultant peptide | |
| UA117259C2 (uk) | Спосіб виготовлення гіпсової штукатурної плити |