PE99399A1 - Compuesto farmaceutico derivado de tiadiazolo quinoleina - Google Patents
Compuesto farmaceutico derivado de tiadiazolo quinoleinaInfo
- Publication number
- PE99399A1 PE99399A1 PE1998000607A PE00060798A PE99399A1 PE 99399 A1 PE99399 A1 PE 99399A1 PE 1998000607 A PE1998000607 A PE 1998000607A PE 00060798 A PE00060798 A PE 00060798A PE 99399 A1 PE99399 A1 PE 99399A1
- Authority
- PE
- Peru
- Prior art keywords
- compound
- tiadiazolo
- quinolein
- pharmaceutical compound
- compound derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA (I), DONDE R1 ES H, ALQUILO C1-C4, ALCOXI C1-C4 O HALO; R2 ES H, ALQUILO C1-C4 O ALCOXI C1-C4. UN COMPUESTO PREFERIDO ES 1-{2-[4-(6-FLUORO-1H-INDOL-3-IL)-1,2,3,6-TETRAHIDRO-1-PIRIDINIL]-1-ETIL}-5,6-DIHIDRO-1H,4H-1,2,5-TIADIAZOLO[4,3,2-IJ]QUINOLEINA-2,2-DIOXO o SU SAL. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION QUE COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA II CON UN COMPUESTO DE FORMULA III, DONDE X ES HALO. EL COMPUESTO I PUEDE SER UTIL PARA TRATAR TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL, COMO DEPRESION AL ENLAZARSE AL RECEPTOR 5-HT2A E INHIBIR LA REABSORCION DE SEROTONINA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700895.7A GB9700895D0 (en) | 1997-01-17 | 1997-01-17 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE99399A1 true PE99399A1 (es) | 1999-11-11 |
Family
ID=10806121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000607A PE99399A1 (es) | 1997-01-17 | 1998-07-09 | Compuesto farmaceutico derivado de tiadiazolo quinoleina |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US20010053783A1 (es) |
| EP (1) | EP0854146B1 (es) |
| JP (1) | JPH10204090A (es) |
| KR (1) | KR20000070221A (es) |
| AR (1) | AR011422A1 (es) |
| AT (1) | ATE190617T1 (es) |
| AU (1) | AU5569298A (es) |
| CA (1) | CA2227132A1 (es) |
| CZ (1) | CZ290318B6 (es) |
| DE (1) | DE69800092T2 (es) |
| DK (1) | DK0854146T3 (es) |
| EA (1) | EA001469B1 (es) |
| ES (1) | ES2144888T3 (es) |
| GB (1) | GB9700895D0 (es) |
| GR (1) | GR3033316T3 (es) |
| HU (1) | HUP0000854A3 (es) |
| ID (1) | ID21920A (es) |
| IL (1) | IL129647A (es) |
| NO (1) | NO993372D0 (es) |
| NZ (1) | NZ335493A (es) |
| PE (1) | PE99399A1 (es) |
| PL (1) | PL334569A1 (es) |
| PT (1) | PT854146E (es) |
| SI (1) | SI0854146T1 (es) |
| SV (1) | SV1998000088A (es) |
| TR (1) | TR199901583T2 (es) |
| TW (1) | TW396156B (es) |
| WO (1) | WO1998031686A1 (es) |
| ZA (1) | ZA98300B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8743098A (en) * | 1997-08-22 | 1999-03-16 | Eli Lilly And Company Limited | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands |
| GB9825413D0 (en) | 1998-11-19 | 1999-01-13 | Lilly Co Eli | Pharmaceutical compounds |
| GB9903784D0 (en) * | 1999-02-18 | 1999-04-14 | Lilly Co Eli | Pharmaceutical compounds |
| AR028945A1 (es) * | 2000-06-19 | 2003-05-28 | Lundbeck & Co As H | Derivados de indol |
| KR101165996B1 (ko) | 2010-04-23 | 2012-07-18 | 주식회사 녹십자 | 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물 |
| CN105949190B (zh) * | 2016-07-04 | 2018-06-29 | 烟台凯博医药科技有限公司 | 一种制备1，8-萘啶及衍生物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662696A2 (fr) * | 1989-12-13 | 1991-12-06 | Rhone Poulenc Sante | Antagonistes de la serotonine, leur preparation et medicaments les contenant. |
| DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
| FR2675801A1 (fr) * | 1991-04-24 | 1992-10-30 | Rhone Poulenc Rorer Sa | Piperidines, leur preparation et les medicaments les contenant. |
| DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
| US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
-
1997
- 1997-01-17 GB GBGB9700895.7A patent/GB9700895D0/en active Pending
-
1998
- 1998-01-13 TW TW087100373A patent/TW396156B/zh not_active IP Right Cessation
- 1998-01-13 US US09/005,995 patent/US20010053783A1/en not_active Abandoned
- 1998-01-14 CZ CZ19991510A patent/CZ290318B6/cs not_active IP Right Cessation
- 1998-01-14 IL IL12964798A patent/IL129647A/en not_active IP Right Cessation
- 1998-01-14 HU HU0000854A patent/HUP0000854A3/hu unknown
- 1998-01-14 WO PCT/GB1998/000113 patent/WO1998031686A1/en not_active Application Discontinuation
- 1998-01-14 JP JP10005897A patent/JPH10204090A/ja active Pending
- 1998-01-14 ES ES98300249T patent/ES2144888T3/es not_active Expired - Lifetime
- 1998-01-14 DK DK98300249T patent/DK0854146T3/da active
- 1998-01-14 AT AT98300249T patent/ATE190617T1/de not_active IP Right Cessation
- 1998-01-14 SI SI9830009T patent/SI0854146T1/xx unknown
- 1998-01-14 AU AU55692/98A patent/AU5569298A/en not_active Abandoned
- 1998-01-14 ID IDW990623A patent/ID21920A/id unknown
- 1998-01-14 ZA ZA98300A patent/ZA98300B/xx unknown
- 1998-01-14 KR KR1019997006447A patent/KR20000070221A/ko not_active Application Discontinuation
- 1998-01-14 EP EP98300249A patent/EP0854146B1/en not_active Expired - Lifetime
- 1998-01-14 EA EA199900667A patent/EA001469B1/ru not_active IP Right Cessation
- 1998-01-14 NZ NZ335493A patent/NZ335493A/xx unknown
- 1998-01-14 DE DE69800092T patent/DE69800092T2/de not_active Expired - Fee Related
- 1998-01-14 PT PT98300249T patent/PT854146E/pt unknown
- 1998-01-14 TR TR1999/01583T patent/TR199901583T2/xx unknown
- 1998-01-14 PL PL98334569A patent/PL334569A1/xx unknown
- 1998-01-15 CA CA002227132A patent/CA2227132A1/en not_active Abandoned
- 1998-01-16 AR ARP980100185A patent/AR011422A1/es unknown
- 1998-07-09 PE PE1998000607A patent/PE99399A1/es not_active Application Discontinuation
- 1998-07-16 SV SV1998000088A patent/SV1998000088A/es unknown
-
1999
- 1999-07-08 NO NO993372A patent/NO993372D0/no not_active Application Discontinuation
-
2000
- 2000-04-26 GR GR20000401000T patent/GR3033316T3/el not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |