DE69800092T2 - Substituierte 4-(6-fluor-[1H]-indol-3-yl)1,2,3,6-Tetrahydropyridin-Derivate für die Behandlung von ZNS-Störungen - Google Patents
Substituierte 4-(6-fluor-[1H]-indol-3-yl)1,2,3,6-Tetrahydropyridin-Derivate für die Behandlung von ZNS-StörungenInfo
- Publication number
- DE69800092T2 DE69800092T2 DE69800092T DE69800092T DE69800092T2 DE 69800092 T2 DE69800092 T2 DE 69800092T2 DE 69800092 T DE69800092 T DE 69800092T DE 69800092 T DE69800092 T DE 69800092T DE 69800092 T2 DE69800092 T2 DE 69800092T2
- Authority
- DE
- Germany
- Prior art keywords
- indol
- fluoro
- substituted
- treatment
- cns disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9700895.7A GB9700895D0 (en) | 1997-01-17 | 1997-01-17 | Pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69800092D1 DE69800092D1 (de) | 2000-04-20 |
DE69800092T2 true DE69800092T2 (de) | 2000-09-14 |
Family
ID=10806121
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69800092T Expired - Fee Related DE69800092T2 (de) | 1997-01-17 | 1998-01-14 | Substituierte 4-(6-fluor-[1H]-indol-3-yl)1,2,3,6-Tetrahydropyridin-Derivate für die Behandlung von ZNS-Störungen |
Country Status (29)
Country | Link |
---|---|
US (1) | US20010053783A1 (de) |
EP (1) | EP0854146B1 (de) |
JP (1) | JPH10204090A (de) |
KR (1) | KR20000070221A (de) |
AR (1) | AR011422A1 (de) |
AT (1) | ATE190617T1 (de) |
AU (1) | AU5569298A (de) |
CA (1) | CA2227132A1 (de) |
CZ (1) | CZ290318B6 (de) |
DE (1) | DE69800092T2 (de) |
DK (1) | DK0854146T3 (de) |
EA (1) | EA001469B1 (de) |
ES (1) | ES2144888T3 (de) |
GB (1) | GB9700895D0 (de) |
GR (1) | GR3033316T3 (de) |
HU (1) | HUP0000854A3 (de) |
ID (1) | ID21920A (de) |
IL (1) | IL129647A (de) |
NO (1) | NO993372D0 (de) |
NZ (1) | NZ335493A (de) |
PE (1) | PE99399A1 (de) |
PL (1) | PL334569A1 (de) |
PT (1) | PT854146E (de) |
SI (1) | SI0854146T1 (de) |
SV (1) | SV1998000088A (de) |
TR (1) | TR199901583T2 (de) |
TW (1) | TW396156B (de) |
WO (1) | WO1998031686A1 (de) |
ZA (1) | ZA98300B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0897921A1 (de) * | 1997-08-22 | 1999-02-24 | Eli Lilly And Company Limited | Benzothiadiazinyl-indolderivate und ihre Verwendung als Serotoninrezeptor-liganden |
GB9825413D0 (en) | 1998-11-19 | 1999-01-13 | Lilly Co Eli | Pharmaceutical compounds |
GB9903784D0 (en) * | 1999-02-18 | 1999-04-14 | Lilly Co Eli | Pharmaceutical compounds |
AR028945A1 (es) * | 2000-06-19 | 2003-05-28 | Lundbeck & Co As H | Derivados de indol |
KR101165996B1 (ko) | 2010-04-23 | 2012-07-18 | 주식회사 녹십자 | 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물 |
CN105949190B (zh) * | 2016-07-04 | 2018-06-29 | 烟台凯博医药科技有限公司 | 一种制备1,8-萘啶及衍生物的方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2662696A2 (fr) * | 1989-12-13 | 1991-12-06 | Rhone Poulenc Sante | Antagonistes de la serotonine, leur preparation et medicaments les contenant. |
DK158590D0 (da) * | 1990-07-02 | 1990-07-02 | Lundbeck & Co As H | Indolderivater |
FR2675801A1 (fr) * | 1991-04-24 | 1992-10-30 | Rhone Poulenc Rorer Sa | Piperidines, leur preparation et les medicaments les contenant. |
DE19500689A1 (de) * | 1995-01-12 | 1996-07-18 | Merck Patent Gmbh | Indolpiperidin-Derivate |
US5576321A (en) * | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
-
1997
- 1997-01-17 GB GBGB9700895.7A patent/GB9700895D0/en active Pending
-
1998
- 1998-01-13 TW TW087100373A patent/TW396156B/zh not_active IP Right Cessation
- 1998-01-13 US US09/005,995 patent/US20010053783A1/en not_active Abandoned
- 1998-01-14 PL PL98334569A patent/PL334569A1/xx unknown
- 1998-01-14 ZA ZA98300A patent/ZA98300B/xx unknown
- 1998-01-14 ES ES98300249T patent/ES2144888T3/es not_active Expired - Lifetime
- 1998-01-14 EA EA199900667A patent/EA001469B1/ru not_active IP Right Cessation
- 1998-01-14 WO PCT/GB1998/000113 patent/WO1998031686A1/en not_active Application Discontinuation
- 1998-01-14 DK DK98300249T patent/DK0854146T3/da active
- 1998-01-14 EP EP98300249A patent/EP0854146B1/de not_active Expired - Lifetime
- 1998-01-14 HU HU0000854A patent/HUP0000854A3/hu unknown
- 1998-01-14 KR KR1019997006447A patent/KR20000070221A/ko not_active Application Discontinuation
- 1998-01-14 AT AT98300249T patent/ATE190617T1/de not_active IP Right Cessation
- 1998-01-14 ID IDW990623A patent/ID21920A/id unknown
- 1998-01-14 DE DE69800092T patent/DE69800092T2/de not_active Expired - Fee Related
- 1998-01-14 PT PT98300249T patent/PT854146E/pt unknown
- 1998-01-14 TR TR1999/01583T patent/TR199901583T2/xx unknown
- 1998-01-14 NZ NZ335493A patent/NZ335493A/xx unknown
- 1998-01-14 SI SI9830009T patent/SI0854146T1/xx unknown
- 1998-01-14 AU AU55692/98A patent/AU5569298A/en not_active Abandoned
- 1998-01-14 JP JP10005897A patent/JPH10204090A/ja active Pending
- 1998-01-14 CZ CZ19991510A patent/CZ290318B6/cs not_active IP Right Cessation
- 1998-01-14 IL IL12964798A patent/IL129647A/en not_active IP Right Cessation
- 1998-01-15 CA CA002227132A patent/CA2227132A1/en not_active Abandoned
- 1998-01-16 AR ARP980100185A patent/AR011422A1/es unknown
- 1998-07-09 PE PE1998000607A patent/PE99399A1/es not_active Application Discontinuation
- 1998-07-16 SV SV1998000088A patent/SV1998000088A/es unknown
-
1999
- 1999-07-08 NO NO993372A patent/NO993372D0/no not_active Application Discontinuation
-
2000
- 2000-04-26 GR GR20000401000T patent/GR3033316T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |