SI0854146T1 - Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders - Google Patents

Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders

Info

Publication number
SI0854146T1
SI0854146T1 SI9830009T SI9830009T SI0854146T1 SI 0854146 T1 SI0854146 T1 SI 0854146T1 SI 9830009 T SI9830009 T SI 9830009T SI 9830009 T SI9830009 T SI 9830009T SI 0854146 T1 SI0854146 T1 SI 0854146T1
Authority
SI
Slovenia
Prior art keywords
tetrahydropyridine
indol
cns
fluoro
disorders
Prior art date
Application number
SI9830009T
Other languages
English (en)
Slovenian (sl)
Inventor
John c/o Eli Lilly and Company Ltd. Fairhurst
Original Assignee
Eli Lilly And Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company Limited filed Critical Eli Lilly And Company Limited
Publication of SI0854146T1 publication Critical patent/SI0854146T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI9830009T 1997-01-17 1998-01-14 Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders SI0854146T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9700895.7A GB9700895D0 (en) 1997-01-17 1997-01-17 Pharmaceutical compounds
EP98300249A EP0854146B1 (de) 1997-01-17 1998-01-14 Substituierte 4-(6-fluor-[1H]-indol-3-yl)1,2,3,6-Tetrahydropyridin-Derivate für die Behandlung von ZNS-Störungen

Publications (1)

Publication Number Publication Date
SI0854146T1 true SI0854146T1 (en) 2000-10-31

Family

ID=10806121

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830009T SI0854146T1 (en) 1997-01-17 1998-01-14 Substituted 4-(6-fluoro-(1H)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders

Country Status (29)

Country Link
US (1) US20010053783A1 (de)
EP (1) EP0854146B1 (de)
JP (1) JPH10204090A (de)
KR (1) KR20000070221A (de)
AR (1) AR011422A1 (de)
AT (1) ATE190617T1 (de)
AU (1) AU5569298A (de)
CA (1) CA2227132A1 (de)
CZ (1) CZ290318B6 (de)
DE (1) DE69800092T2 (de)
DK (1) DK0854146T3 (de)
EA (1) EA001469B1 (de)
ES (1) ES2144888T3 (de)
GB (1) GB9700895D0 (de)
GR (1) GR3033316T3 (de)
HU (1) HUP0000854A3 (de)
ID (1) ID21920A (de)
IL (1) IL129647A (de)
NO (1) NO993372D0 (de)
NZ (1) NZ335493A (de)
PE (1) PE99399A1 (de)
PL (1) PL334569A1 (de)
PT (1) PT854146E (de)
SI (1) SI0854146T1 (de)
SV (1) SV1998000088A (de)
TR (1) TR199901583T2 (de)
TW (1) TW396156B (de)
WO (1) WO1998031686A1 (de)
ZA (1) ZA98300B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8743098A (en) * 1997-08-22 1999-03-16 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
GB9825413D0 (en) 1998-11-19 1999-01-13 Lilly Co Eli Pharmaceutical compounds
GB9903784D0 (en) * 1999-02-18 1999-04-14 Lilly Co Eli Pharmaceutical compounds
AR028945A1 (es) * 2000-06-19 2003-05-28 Lundbeck & Co As H Derivados de indol
KR101165996B1 (ko) 2010-04-23 2012-07-18 주식회사 녹십자 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물
CN105949190B (zh) * 2016-07-04 2018-06-29 烟台凯博医药科技有限公司 一种制备1，8-萘啶及衍生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
DK158590D0 (da) * 1990-07-02 1990-07-02 Lundbeck & Co As H Indolderivater
FR2675801A1 (fr) * 1991-04-24 1992-10-30 Rhone Poulenc Rorer Sa Piperidines, leur preparation et les medicaments les contenant.
DE19500689A1 (de) * 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems

Also Published As

Publication number Publication date
HUP0000854A3 (en) 2002-06-28
ID21920A (id) 1999-08-12
AR011422A1 (es) 2000-08-16
PT854146E (pt) 2000-08-31
EA001469B1 (ru) 2001-04-23
SV1998000088A (es) 2000-10-10
ES2144888T3 (es) 2000-06-16
DE69800092T2 (de) 2000-09-14
EP0854146B1 (de) 2000-03-15
EP0854146A1 (de) 1998-07-22
CZ151099A3 (cs) 1999-09-15
DE69800092D1 (de) 2000-04-20
CA2227132A1 (en) 1998-07-17
KR20000070221A (ko) 2000-11-25
WO1998031686A1 (en) 1998-07-23
AU5569298A (en) 1998-08-07
NO993372L (no) 1999-07-08
TR199901583T2 (xx) 1999-11-22
EA199900667A1 (ru) 2000-02-28
PE99399A1 (es) 1999-11-11
CZ290318B6 (cs) 2002-07-17
IL129647A0 (en) 2000-02-29
HUP0000854A2 (hu) 2000-11-28
NO993372D0 (no) 1999-07-08
ZA98300B (en) 1998-09-10
IL129647A (en) 2002-02-10
JPH10204090A (ja) 1998-08-04
NZ335493A (en) 2000-09-29
US20010053783A1 (en) 2001-12-20
PL334569A1 (en) 2000-03-13
GB9700895D0 (en) 1997-03-05
DK0854146T3 (da) 2000-06-05
GR3033316T3 (en) 2000-09-29
TW396156B (en) 2000-07-01
ATE190617T1 (de) 2000-04-15

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