IL129647A - -4 (-6 Fluoro (-1H) indole - 3 il) - 6,3,2,1 tetrahydro pyridines are converted, their preparation and pharmaceutical preparations containing them for the treatment of disorders of the central nervous system - Google Patents

-4 (-6 Fluoro (-1H) indole - 3 il) - 6,3,2,1 tetrahydro pyridines are converted, their preparation and pharmaceutical preparations containing them for the treatment of disorders of the central nervous system

Info

Publication number
IL129647A
IL129647A IL12964798A IL12964798A IL129647A IL 129647 A IL129647 A IL 129647A IL 12964798 A IL12964798 A IL 12964798A IL 12964798 A IL12964798 A IL 12964798A IL 129647 A IL129647 A IL 129647A
Authority
IL
Israel
Prior art keywords
fluoro
hydrogen
indol
compound
compound according
Prior art date
Application number
IL12964798A
Other languages
English (en)
Hebrew (he)
Other versions
IL129647A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL129647A0 publication Critical patent/IL129647A0/xx
Publication of IL129647A publication Critical patent/IL129647A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL12964798A 1997-01-17 1998-01-14 -4 (-6 Fluoro (-1H) indole - 3 il) - 6,3,2,1 tetrahydro pyridines are converted, their preparation and pharmaceutical preparations containing them for the treatment of disorders of the central nervous system IL129647A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9700895.7A GB9700895D0 (en) 1997-01-17 1997-01-17 Pharmaceutical compounds
PCT/GB1998/000113 WO1998031686A1 (en) 1997-01-17 1998-01-14 Substituted 4-(6-fluoro-(1h)-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of cns-disorders

Publications (2)

Publication Number Publication Date
IL129647A0 IL129647A0 (en) 2000-02-29
IL129647A true IL129647A (en) 2002-02-10

Family

ID=10806121

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12964798A IL129647A (en) 1997-01-17 1998-01-14 -4 (-6 Fluoro (-1H) indole - 3 il) - 6,3,2,1 tetrahydro pyridines are converted, their preparation and pharmaceutical preparations containing them for the treatment of disorders of the central nervous system

Country Status (29)

Country Link
US (1) US20010053783A1 (de)
EP (1) EP0854146B1 (de)
JP (1) JPH10204090A (de)
KR (1) KR20000070221A (de)
AR (1) AR011422A1 (de)
AT (1) ATE190617T1 (de)
AU (1) AU5569298A (de)
CA (1) CA2227132A1 (de)
CZ (1) CZ290318B6 (de)
DE (1) DE69800092T2 (de)
DK (1) DK0854146T3 (de)
EA (1) EA001469B1 (de)
ES (1) ES2144888T3 (de)
GB (1) GB9700895D0 (de)
GR (1) GR3033316T3 (de)
HU (1) HUP0000854A3 (de)
ID (1) ID21920A (de)
IL (1) IL129647A (de)
NO (1) NO993372L (de)
NZ (1) NZ335493A (de)
PE (1) PE99399A1 (de)
PL (1) PL334569A1 (de)
PT (1) PT854146E (de)
SI (1) SI0854146T1 (de)
SV (1) SV1998000088A (de)
TR (1) TR199901583T2 (de)
TW (1) TW396156B (de)
WO (1) WO1998031686A1 (de)
ZA (1) ZA98300B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8743098A (en) * 1997-08-22 1999-03-16 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
GB9825413D0 (en) 1998-11-19 1999-01-13 Lilly Co Eli Pharmaceutical compounds
GB9903784D0 (en) * 1999-02-18 1999-04-14 Lilly Co Eli Pharmaceutical compounds
AR028945A1 (es) * 2000-06-19 2003-05-28 Lundbeck & Co As H Derivados de indol
KR101165996B1 (ko) 2010-04-23 2012-07-18 주식회사 녹십자 프탈라지논 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물
CN105949190B (zh) * 2016-07-04 2018-06-29 烟台凯博医药科技有限公司 一种制备1，8-萘啶及衍生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
DK158590D0 (da) * 1990-07-02 1990-07-02 Lundbeck & Co As H Indolderivater
FR2675801A1 (fr) * 1991-04-24 1992-10-30 Rhone Poulenc Rorer Sa Piperidines, leur preparation et les medicaments les contenant.
DE19500689A1 (de) * 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
US5576321A (en) * 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems

Also Published As

Publication number Publication date
DE69800092T2 (de) 2000-09-14
NZ335493A (en) 2000-09-29
PL334569A1 (en) 2000-03-13
CZ290318B6 (cs) 2002-07-17
NO993372D0 (no) 1999-07-08
DE69800092D1 (de) 2000-04-20
TW396156B (en) 2000-07-01
AR011422A1 (es) 2000-08-16
ATE190617T1 (de) 2000-04-15
SI0854146T1 (en) 2000-10-31
AU5569298A (en) 1998-08-07
HUP0000854A3 (en) 2002-06-28
KR20000070221A (ko) 2000-11-25
GB9700895D0 (en) 1997-03-05
PE99399A1 (es) 1999-11-11
SV1998000088A (es) 2000-10-10
EA199900667A1 (ru) 2000-02-28
JPH10204090A (ja) 1998-08-04
CZ151099A3 (cs) 1999-09-15
DK0854146T3 (da) 2000-06-05
EP0854146A1 (de) 1998-07-22
WO1998031686A1 (en) 1998-07-23
NO993372L (no) 1999-07-08
ID21920A (id) 1999-08-12
EA001469B1 (ru) 2001-04-23
PT854146E (pt) 2000-08-31
TR199901583T2 (xx) 1999-11-22
CA2227132A1 (en) 1998-07-17
GR3033316T3 (en) 2000-09-29
EP0854146B1 (de) 2000-03-15
US20010053783A1 (en) 2001-12-20
IL129647A0 (en) 2000-02-29
ZA98300B (en) 1998-09-10
ES2144888T3 (es) 2000-06-16
HUP0000854A2 (hu) 2000-11-28

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees