PE49596A1 - Ariloxicicloalquenil y ariloxiiminocicloalquenilhidroxiurea - Google Patents
Ariloxicicloalquenil y ariloxiiminocicloalquenilhidroxiureaInfo
- Publication number
- PE49596A1 PE49596A1 PE1995284002A PE28400295A PE49596A1 PE 49596 A1 PE49596 A1 PE 49596A1 PE 1995284002 A PE1995284002 A PE 1995284002A PE 28400295 A PE28400295 A PE 28400295A PE 49596 A1 PE49596 A1 PE 49596A1
- Authority
- PE
- Peru
- Prior art keywords
- chr1
- furilo
- haloalkyl
- preference
- alkylene
- Prior art date
Links
- 101100277337 Arabidopsis thaliana DDM1 gene Proteins 0.000 abstract 3
- 101150113676 chr1 gene Proteins 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 235000010290 biphenyl Nutrition 0.000 abstract 1
- 239000004305 biphenyl Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I DONDE: Ar SE SELECCIONA ENTRE EL GRUPO COMPUESTO POR: a) FENILO, NAFTILO Y BIFENILO, CADA UNO OPCIONALMENTE SUSTITUIDO CON UNO A TRES SUSTITUYENTES SELECCIONADOS ENTRE ALQUILO DE C1-C4, HALOALQUILO C1-C4, HIDROXIALQUILO DE C1-C4 ENTRE OTROS; b) FURILO, BENZO[b]FURILO, TIENILO ENTRE OTROS, OPCIONALMENTE SUSTITUIDOS CON UNA A TRES SUSTITUYENTES SELECCIONADOS ENTRE ALQUILO C1-C4, HALOALQUILO C1-C4, HALO ENTRE OTROS, DE PREFERENCIA Ar SE SELECCIONA ENTRE EL GRUPO (a); X SE SELECCIONA ENTRE ALQUILENO C1-C4, ALQUENILENO C2-C4, (CHR1)m-Q1-(CHR2)n, -O-(CHR1)j-Q2- y -(CHR1)-O-N= ENTRE OTROS; p ES 1 o 2, DE PREFERENCIA EL PRIMERO; Y ES H, ALQUILO C1-C4, HALOALQUILO C1-C4 ENTRE OTROS, DE PREFERENCIA ES HIDROGENO; Z ES H o ALQUILO DE C1-C4, DE PREFERENCIA ES HIDROGENO; M ES H, UN CATION FARMACEUTICAMENTE ACEPTABLE O UN GRUPO ESCINDIBLE METABOLICAMENTE. ESTE COMPUESTO SE CARACTERIZA POR SER INHIBIDOR DE LA 5-LIPOXIGENASA, SIENDO UTILIZADO EN EL TRATAMIENTO DE ENFERMEDADES TAL COMO INFLAMATORIA, CARDIOVASCULAR Y ALERGICA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9401897 | 1994-11-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE49596A1 true PE49596A1 (es) | 1996-11-27 |
Family
ID=14098792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1995284002A PE49596A1 (es) | 1994-11-10 | 1995-11-07 | Ariloxicicloalquenil y ariloxiiminocicloalquenilhidroxiurea |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5798383A (es) |
| EP (1) | EP0790981B1 (es) |
| KR (1) | KR0182321B1 (es) |
| AR (1) | AR002239A1 (es) |
| AT (1) | ATE184272T1 (es) |
| AU (1) | AU690354B2 (es) |
| BR (1) | BR9505130A (es) |
| CA (1) | CA2205033C (es) |
| CO (1) | CO4520227A1 (es) |
| CZ (1) | CZ282832B6 (es) |
| DE (1) | DE69512080T2 (es) |
| ES (1) | ES2135066T3 (es) |
| FI (1) | FI113643B (es) |
| GR (1) | GR3031378T3 (es) |
| IL (1) | IL115853A (es) |
| MX (1) | MX9703485A (es) |
| MY (1) | MY112595A (es) |
| NO (1) | NO305362B1 (es) |
| NZ (1) | NZ280434A (es) |
| PE (1) | PE49596A1 (es) |
| PL (1) | PL179023B1 (es) |
| RU (1) | RU2119479C1 (es) |
| SG (1) | SG44332A1 (es) |
| TR (1) | TR199501413A2 (es) |
| TW (1) | TW363960B (es) |
| WO (1) | WO1996015106A1 (es) |
| ZA (1) | ZA959512B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0217294D0 (en) * | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicaments |
| JP7128447B2 (ja) * | 2017-02-03 | 2022-08-31 | 日産化学株式会社 | ウレア結合を有する構造単位を有するポリマーを含むレジスト下層膜形成組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3007138B2 (ja) * | 1990-11-27 | 2000-02-07 | ファイザー製薬株式会社 | 新規なヒドロキサム酸とｎ―ヒドロキシ尿素誘導体およびそれらの組成物 |
| US5326883A (en) * | 1992-12-18 | 1994-07-05 | Abbott Laboratories | Oxime ether derivatives having lipoxygenase inhibitory activity |
| DE69411003T2 (de) * | 1993-04-07 | 1998-10-08 | Pfizer Inc., New York, N.Y. | Cycloalkylhydroxyharnstoffe und ihre verwendung als lipoxy-genase-inhibitoren |
| TW448144B (en) * | 1993-08-19 | 2001-08-01 | Pfizer | Phenoxyphenyl cyclopentenyl hydroxyureas |
-
1995
- 1995-05-26 AT AT95918112T patent/ATE184272T1/de not_active IP Right Cessation
- 1995-05-26 DE DE69512080T patent/DE69512080T2/de not_active Expired - Fee Related
- 1995-05-26 CA CA002205033A patent/CA2205033C/en not_active Expired - Fee Related
- 1995-05-26 ES ES95918112T patent/ES2135066T3/es not_active Expired - Lifetime
- 1995-05-26 EP EP95918112A patent/EP0790981B1/en not_active Expired - Lifetime
- 1995-05-26 MX MX9703485A patent/MX9703485A/es unknown
- 1995-05-26 US US08/836,452 patent/US5798383A/en not_active Expired - Fee Related
- 1995-05-26 WO PCT/IB1995/000399 patent/WO1996015106A1/en active IP Right Grant
- 1995-10-30 MY MYPI95003267A patent/MY112595A/en unknown
- 1995-11-01 AR ARP950100014A patent/AR002239A1/es unknown
- 1995-11-02 IL IL11585395A patent/IL115853A/xx active IP Right Grant
- 1995-11-03 SG SG1995001721A patent/SG44332A1/en unknown
- 1995-11-07 PE PE1995284002A patent/PE49596A1/es not_active Application Discontinuation
- 1995-11-08 TW TW084111851A patent/TW363960B/zh active
- 1995-11-09 KR KR1019950040425A patent/KR0182321B1/ko not_active IP Right Cessation
- 1995-11-09 BR BR9505130A patent/BR9505130A/pt not_active IP Right Cessation
- 1995-11-09 PL PL95311325A patent/PL179023B1/pl unknown
- 1995-11-09 NZ NZ280434A patent/NZ280434A/en unknown
- 1995-11-09 ZA ZA959512A patent/ZA959512B/xx unknown
- 1995-11-09 AU AU37764/95A patent/AU690354B2/en not_active Ceased
- 1995-11-09 CZ CZ952942A patent/CZ282832B6/cs not_active IP Right Cessation
- 1995-11-09 NO NO954530A patent/NO305362B1/no not_active IP Right Cessation
- 1995-11-09 RU RU95119414/04A patent/RU2119479C1/ru not_active IP Right Cessation
- 1995-11-10 CO CO95053260A patent/CO4520227A1/es unknown
- 1995-11-10 TR TR95/01413A patent/TR199501413A2/xx unknown
-
1997
- 1997-05-09 FI FI971994A patent/FI113643B/fi not_active IP Right Cessation
-
1999
- 1999-09-29 GR GR990402472T patent/GR3031378T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |