NO166129C - Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydro-9h-pyrido (3,4-b)indoler. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydro-9h-pyrido (3,4-b)indoler.

Info

Publication number
NO166129C
NO166129C NO883487A NO883487A NO166129C NO 166129 C NO166129 C NO 166129C NO 883487 A NO883487 A NO 883487A NO 883487 A NO883487 A NO 883487A NO 166129 C NO166129 C NO 166129C
Authority
NO
Norway
Prior art keywords
group
denotes
indoles
pyrido
formula
Prior art date
Application number
NO883487A
Other languages
English (en)
Other versions
NO883487L (no
NO883487D0 (no
NO166129B (no
Inventor
Mireille Sevrin
Pascal George
Jacques Menin
Claude Morel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO883487D0 publication Critical patent/NO883487D0/no
Publication of NO883487L publication Critical patent/NO883487L/no
Publication of NO166129B publication Critical patent/NO166129B/no
Publication of NO166129C publication Critical patent/NO166129C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO883487A 1987-08-07 1988-08-05 Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydro-9h-pyrido (3,4-b)indoler. NO166129C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8711291A FR2619111B1 (fr) 1987-08-07 1987-08-07 Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique

Publications (4)

Publication Number Publication Date
NO883487D0 NO883487D0 (no) 1988-08-05
NO883487L NO883487L (no) 1989-02-08
NO166129B NO166129B (no) 1991-02-25
NO166129C true NO166129C (no) 1991-06-05

Family

ID=9354027

Family Applications (1)

Application Number Title Priority Date Filing Date
NO883487A NO166129C (no) 1987-08-07 1988-08-05 Analogifremgangsmaate for fremstilling av terapeutisk aktive tetrahydro-9h-pyrido (3,4-b)indoler.

Country Status (17)

Country Link
US (1) US4977159A (no)
EP (1) EP0302788B1 (no)
JP (1) JPS6466185A (no)
KR (1) KR890003756A (no)
AT (1) ATE72436T1 (no)
AU (1) AU597188B2 (no)
DE (1) DE3868301D1 (no)
DK (1) DK437788A (no)
FI (1) FI883669A7 (no)
FR (1) FR2619111B1 (no)
GR (1) GR3003920T3 (no)
HU (1) HU198931B (no)
IL (1) IL87343A0 (no)
NO (1) NO166129C (no)
NZ (1) NZ225706A (no)
PT (1) PT88206B (no)
ZA (1) ZA885788B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978669A (en) * 1989-06-08 1990-12-18 Neurex Corporation Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5455254A (en) * 1991-02-15 1995-10-03 Mondadori; Cesare Substituted benzofuranylpiperidine as a nootropic agent
RU2095339C1 (ru) * 1991-10-17 1997-11-10 Циба-Гейги АГ Производные гидрохинона в свободном виде или в виде соли, способы их получения, производные пиперидина и способы их получения
US5693807A (en) * 1992-10-14 1997-12-02 Ciba-Geigy Corporation Substituted hydroquinone derivatives
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
WO1996012721A1 (en) * 1994-10-20 1996-05-02 American Home Products Corporation Indole derivatives useful as serotonergic agents
US6255302B1 (en) 1998-12-17 2001-07-03 American Home Products Corporation 1,4-piperazine derivatives
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
CO5370679A1 (es) 1999-06-01 2004-02-27 Smithkline Beecham Corp Inhibidores fab 1
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
PE20010635A1 (es) * 1999-10-08 2001-08-15 Smithkline Beecham Corp Inhibidores de fab i utiles para el tratamiento de infecciones bacterianas
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
JP4078074B2 (ja) 1999-12-10 2008-04-23 ファイザー・プロダクツ・インク ピロロ［２，３−ｄ］ピリミジン化合物
DK1560584T3 (da) 2001-04-06 2009-05-18 Affinium Pharm Inc Fab I inhibitorer
US7812035B2 (en) * 2001-12-11 2010-10-12 Sepracor Inc. 4-substituted piperidines, and methods of use thereof
JP2006508976A (ja) * 2002-11-21 2006-03-16 ファイザー・プロダクツ・インク ３−アミノ−ピペラジン誘導体及び製造法
DK1575951T3 (da) 2002-12-06 2014-09-15 Debiopharm Int Sa Heterocykliske forbindelser, fremgangsmåder til fremstilling deraf og deres anvendelse i terapi
CA2519429C (en) 2003-03-17 2013-08-06 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
DE602004017714D1 (de) * 2003-04-29 2008-12-24 Oscient Pharmaceuticals ANTIBIOTISCHE TETRAHYDRO-b-CARBOLINDERIVATIVE
KR101299399B1 (ko) 2004-06-04 2013-08-22 아피늄 파마슈티컬스, 인크. 치료제, 및 그의 제조 및 사용 방법
WO2008009122A1 (en) 2006-07-20 2008-01-24 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab i inhibitors
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
BR122021020778B1 (pt) 2012-06-19 2022-07-12 Debiopharm International Sa Derivados de pró-fármaco de (e)-n-metil-n-((3-metilbenzofuran-2-il) metil)-3-(7-oxo-5,6,7,8-tetraidro- 1, 8- naftirindin-3-il) acrilamida
SI3419628T1 (sl) 2016-02-26 2021-03-31 Debiopharm International Sa Zdravilo za zdravljenje infekcij diabetičnega stopala
PH12021551922A1 (en) 2019-02-14 2022-05-23 Debiopharm Int Sa Afabicin formulation, method for making the same
UA129222C2 (uk) 2019-06-14 2025-02-12 Дебіофарм Інтернешнл С.А. Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539407A (en) * 1983-12-13 1985-09-03 American Home Products Corporation β-Carboline anticonvulsants
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders

Also Published As

Publication number Publication date
ATE72436T1 (de) 1992-02-15
DE3868301D1 (de) 1992-03-19
JPS6466185A (en) 1989-03-13
US4977159A (en) 1990-12-11
AU597188B2 (en) 1990-05-24
EP0302788A1 (fr) 1989-02-08
KR890003756A (ko) 1989-04-17
IL87343A0 (en) 1989-01-31
NO883487L (no) 1989-02-08
NO883487D0 (no) 1988-08-05
AU2044588A (en) 1989-02-09
NO166129B (no) 1991-02-25
FR2619111A1 (fr) 1989-02-10
EP0302788B1 (fr) 1992-02-05
DK437788A (da) 1989-02-07
PT88206A (pt) 1989-06-30
ZA885788B (en) 1989-04-26
GR3003920T3 (no) 1993-03-16
HUT48242A (en) 1989-05-29
FI883669A7 (fi) 1989-02-08
DK437788D0 (da) 1988-08-05
FR2619111B1 (fr) 1991-01-11
NZ225706A (en) 1990-04-26
PT88206B (pt) 1995-05-04
HU198931B (en) 1989-12-28
FI883669A0 (fi) 1988-08-05

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