DK437788A - Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater - Google Patents

Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater

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Publication number
DK437788A
DK437788A DK437788A DK437788A DK437788A DK 437788 A DK437788 A DK 437788A DK 437788 A DK437788 A DK 437788A DK 437788 A DK437788 A DK 437788A DK 437788 A DK437788 A DK 437788A
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DK
Denmark
Prior art keywords
group
derivatives
denotes
formula
pyrido
Prior art date
Application number
DK437788A
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English (en)
Other versions
DK437788D0 (da
Inventor
Mireille Sevrin
Pascal George
Jacques Menin
Claude Morel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK437788D0 publication Critical patent/DK437788D0/da
Publication of DK437788A publication Critical patent/DK437788A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK437788A 1987-08-07 1988-08-05 Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater DK437788A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8711291A FR2619111B1 (fr) 1987-08-07 1987-08-07 Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
DK437788D0 DK437788D0 (da) 1988-08-05
DK437788A true DK437788A (da) 1989-02-07

Family

ID=9354027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK437788A DK437788A (da) 1987-08-07 1988-08-05 Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater

Country Status (17)

Country Link
US (1) US4977159A (da)
EP (1) EP0302788B1 (da)
JP (1) JPS6466185A (da)
KR (1) KR890003756A (da)
AT (1) ATE72436T1 (da)
AU (1) AU597188B2 (da)
DE (1) DE3868301D1 (da)
DK (1) DK437788A (da)
FI (1) FI883669A (da)
FR (1) FR2619111B1 (da)
GR (1) GR3003920T3 (da)
HU (1) HU198931B (da)
IL (1) IL87343A0 (da)
NO (1) NO166129C (da)
NZ (1) NZ225706A (da)
PT (1) PT88206B (da)
ZA (1) ZA885788B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978669A (en) * 1989-06-08 1990-12-18 Neurex Corporation Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5455254A (en) * 1991-02-15 1995-10-03 Mondadori; Cesare Substituted benzofuranylpiperidine as a nootropic agent
RU2095339C1 (ru) * 1991-10-17 1997-11-10 Циба-Гейги АГ Производные гидрохинона в свободном виде или в виде соли, способы их получения, производные пиперидина и способы их получения
US5693807A (en) * 1992-10-14 1997-12-02 Ciba-Geigy Corporation Substituted hydroquinone derivatives
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
WO1996012721A1 (en) * 1994-10-20 1996-05-02 American Home Products Corporation Indole derivatives useful as serotonergic agents
US6255302B1 (en) 1998-12-17 2001-07-03 American Home Products Corporation 1,4-piperazine derivatives
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
AR024158A1 (es) 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
JP4803935B2 (ja) * 1999-10-08 2011-10-26 アフィニアム・ファーマシューティカルズ・インコーポレイテッド Ｆａｂｉ阻害剤
EA006227B1 (ru) 1999-12-10 2005-10-27 Пфайзер Продактс Инк. СОЕДИНЕНИЯ ПИРРОЛО[2,3-d]ПИРИМИДИНА
ATE420640T1 (de) 2001-04-06 2009-01-15 Affinium Pharm Inc Fab-i-inhibitoren
US7812035B2 (en) * 2001-12-11 2010-10-12 Sepracor Inc. 4-substituted piperidines, and methods of use thereof
CN1726192A (zh) 2002-11-21 2006-01-25 辉瑞产品公司 3－氨基－哌啶衍生物及其制备方法
US7790709B2 (en) 2002-12-06 2010-09-07 Affinium Pharmaceuticals, Inc. Heterocyclic compounds, methods of making them and their use in therapy
CA2519429C (en) 2003-03-17 2013-08-06 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
ATE414082T1 (de) * 2003-04-29 2008-11-15 Oscient Pharmaceuticals Antibiotische tetrahydro-b-carbolinderivative
DK1828167T3 (da) 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
CA2658506C (en) 2006-07-20 2016-01-26 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab 1 inhibitors
US8263613B2 (en) 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
NZ702695A (en) 2012-06-19 2015-10-30 Debiopharm Int Sa Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
PT3419628T (pt) 2016-02-26 2021-01-05 Debiopharm Int Sa Medicamento para o tratamento de infeções do pé diabético

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539407A (en) * 1983-12-13 1985-09-03 American Home Products Corporation β-Carboline anticonvulsants
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders

Also Published As

Publication number Publication date
ZA885788B (en) 1989-04-26
FI883669A (fi) 1989-02-08
ATE72436T1 (de) 1992-02-15
NO166129B (no) 1991-02-25
GR3003920T3 (da) 1993-03-16
PT88206B (pt) 1995-05-04
AU597188B2 (en) 1990-05-24
JPS6466185A (en) 1989-03-13
NO883487D0 (no) 1988-08-05
NZ225706A (en) 1990-04-26
FR2619111A1 (fr) 1989-02-10
EP0302788A1 (fr) 1989-02-08
DE3868301D1 (de) 1992-03-19
NO883487L (no) 1989-02-08
IL87343A0 (en) 1989-01-31
US4977159A (en) 1990-12-11
PT88206A (pt) 1989-06-30
HU198931B (en) 1989-12-28
KR890003756A (ko) 1989-04-17
FR2619111B1 (fr) 1991-01-11
FI883669A0 (fi) 1988-08-05
AU2044588A (en) 1989-02-09
DK437788D0 (da) 1988-08-05
NO166129C (no) 1991-06-05
HUT48242A (en) 1989-05-29
EP0302788B1 (fr) 1992-02-05

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