FI883669A - 1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning. - Google Patents

1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning. Download PDF

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Publication number
FI883669A
FI883669A FI883669A FI883669A FI883669A FI 883669 A FI883669 A FI 883669A FI 883669 A FI883669 A FI 883669A FI 883669 A FI883669 A FI 883669A FI 883669 A FI883669 A FI 883669A
Authority
FI
Finland
Prior art keywords
group
denotes
terapeutiska
indolderivat
anvaendning
Prior art date
Application number
FI883669A
Other languages
English (en)
Other versions
FI883669A0 (fi
Inventor
Mireille Sevrin
Pascal George
Jacques Menin
Claude Morel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI883669A0 publication Critical patent/FI883669A0/fi
Publication of FI883669A publication Critical patent/FI883669A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI883669A 1987-08-07 1988-08-05 1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning. FI883669A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8711291A FR2619111B1 (fr) 1987-08-07 1987-08-07 Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FI883669A0 FI883669A0 (fi) 1988-08-05
FI883669A true FI883669A (fi) 1989-02-08

Family

ID=9354027

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883669A FI883669A (fi) 1987-08-07 1988-08-05 1-/(4-piperidinyl) metyl/ -1,2,3,4-tetrahydro-9h-pyrido/3.4-b/ indolderivat, deras framstaellning och terapeutiska anvaendning.

Country Status (17)

Country Link
US (1) US4977159A (fi)
EP (1) EP0302788B1 (fi)
JP (1) JPS6466185A (fi)
KR (1) KR890003756A (fi)
AT (1) ATE72436T1 (fi)
AU (1) AU597188B2 (fi)
DE (1) DE3868301D1 (fi)
DK (1) DK437788A (fi)
FI (1) FI883669A (fi)
FR (1) FR2619111B1 (fi)
GR (1) GR3003920T3 (fi)
HU (1) HU198931B (fi)
IL (1) IL87343A0 (fi)
NO (1) NO166129C (fi)
NZ (1) NZ225706A (fi)
PT (1) PT88206B (fi)
ZA (1) ZA885788B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978669A (en) * 1989-06-08 1990-12-18 Neurex Corporation Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5455254A (en) * 1991-02-15 1995-10-03 Mondadori; Cesare Substituted benzofuranylpiperidine as a nootropic agent
RU2095339C1 (ru) * 1991-10-17 1997-11-10 Циба-Гейги АГ Производные гидрохинона в свободном виде или в виде соли, способы их получения, производные пиперидина и способы их получения
US5693807A (en) * 1992-10-14 1997-12-02 Ciba-Geigy Corporation Substituted hydroquinone derivatives
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
WO1996012721A1 (en) * 1994-10-20 1996-05-02 American Home Products Corporation Indole derivatives useful as serotonergic agents
US6255302B1 (en) 1998-12-17 2001-07-03 American Home Products Corporation 1,4-piperazine derivatives
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
AR024158A1 (es) 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
JP4803935B2 (ja) 1999-10-08 2011-10-26 アフィニアム・ファーマシューティカルズ・インコーポレイテッド Ｆａｂｉ阻害剤
PL218519B1 (pl) 1999-12-10 2014-12-31 Pfizer Prod Inc Związki pirolo [2,3-d] pirymidynowe, środek farmaceutyczny zawierający te związki oraz ich zastosowanie
DE60230934D1 (de) * 2001-04-06 2009-03-05 Affinium Pharm Inc Fab-i-inhibitoren
US7812035B2 (en) * 2001-12-11 2010-10-12 Sepracor Inc. 4-substituted piperidines, and methods of use thereof
BR0316470A (pt) * 2002-11-21 2005-10-11 Pfizer Prod Inc Derivados de 3-amino-piperadina e métodos de preparação
ES2518316T3 (es) 2002-12-06 2014-11-05 Debiopharm International Sa Compuestos heterocíclicos, métodos de fabricación de los mismos y su uso en terapia
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
CA2524125A1 (en) * 2003-04-29 2004-11-11 Oscient Pharmaceuticals Antibiotic tetrahydro-.beta.-carboline derivatives
PT1828167E (pt) 2004-06-04 2014-10-08 Debiopharm Int Sa Derivados de acrilamida como agentes antibióticos
WO2008009122A1 (en) 2006-07-20 2008-01-24 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab i inhibitors
EP3255045A1 (en) 2007-02-16 2017-12-13 Debiopharm International SA Salts, prodrugs and polymorphs of fab i inhibitors
LT2861608T (lt) 2012-06-19 2019-07-10 Debiopharm International Sa (e)-n-metil-n-((3-metilbenzofuran-2-il)metil)-3-(7-okso-5,6,7,8-tetrahidro-1,8-nafthidrin-3-il)akrilamido provaisto dariniai
HUE052140T2 (hu) 2016-02-26 2021-04-28 Debiopharm Int Sa Diabéteszes lábfertõzések kezelésére szolgáló gyógyszer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539407A (en) * 1983-12-13 1985-09-03 American Home Products Corporation β-Carboline anticonvulsants
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders

Also Published As

Publication number Publication date
ZA885788B (en) 1989-04-26
PT88206B (pt) 1995-05-04
ATE72436T1 (de) 1992-02-15
US4977159A (en) 1990-12-11
GR3003920T3 (fi) 1993-03-16
DK437788A (da) 1989-02-07
AU2044588A (en) 1989-02-09
JPS6466185A (en) 1989-03-13
FR2619111A1 (fr) 1989-02-10
NO166129C (no) 1991-06-05
NO883487L (no) 1989-02-08
EP0302788A1 (fr) 1989-02-08
HU198931B (en) 1989-12-28
KR890003756A (ko) 1989-04-17
DE3868301D1 (de) 1992-03-19
PT88206A (pt) 1989-06-30
HUT48242A (en) 1989-05-29
DK437788D0 (da) 1988-08-05
NO883487D0 (no) 1988-08-05
EP0302788B1 (fr) 1992-02-05
NZ225706A (en) 1990-04-26
FR2619111B1 (fr) 1991-01-11
NO166129B (no) 1991-02-25
FI883669A0 (fi) 1988-08-05
IL87343A0 (en) 1989-01-31
AU597188B2 (en) 1990-05-24

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Owner name: SYNTHELABO