PE20211473A1 - Conjugados de anticuerpo-farmaco de herboxidieno y metodos de uso - Google Patents
Conjugados de anticuerpo-farmaco de herboxidieno y metodos de usoInfo
- Publication number
- PE20211473A1 PE20211473A1 PE2021000860A PE2021000860A PE20211473A1 PE 20211473 A1 PE20211473 A1 PE 20211473A1 PE 2021000860 A PE2021000860 A PE 2021000860A PE 2021000860 A PE2021000860 A PE 2021000860A PE 20211473 A1 PE20211473 A1 PE 20211473A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- antibody
- hydroxyl
- herboxidiene
- methods
- Prior art date
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- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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Applications Claiming Priority (4)
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| US201862779400P | 2018-12-13 | 2018-12-13 | |
| US201862779406P | 2018-12-13 | 2018-12-13 | |
| US201962941220P | 2019-11-27 | 2019-11-27 | |
| PCT/US2019/066029 WO2020123836A2 (en) | 2018-12-13 | 2019-12-12 | Herboxidiene splicing modulator antibody-drug conjugates and methods of use |
Publications (1)
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| PE20211473A1 true PE20211473A1 (es) | 2021-08-05 |
Family
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| US12172986B2 (en) | 2018-06-01 | 2024-12-24 | Eisai R&D Management Co., Ltd | Splicing modulator antibody-drug conjugates and methods of use |
| US11998544B2 (en) | 2018-06-01 | 2024-06-04 | Eisai R&D Management Co., Ltd. | Methods of using splicing modulators |
| PE20211473A1 (es) | 2018-12-13 | 2021-08-05 | Eisai Randd Man Co Ltd | Conjugados de anticuerpo-farmaco de herboxidieno y metodos de uso |
| CN114729042B (zh) | 2019-11-07 | 2026-03-03 | 卫材R&D管理有限公司 | 抗间皮素艾日布林抗体-药物缀合物及使用方法 |
| AU2021284401A1 (en) | 2020-06-05 | 2023-01-05 | Eisai R&D Management Co., Ltd. | Anti-BCMA antibody-drug conjugates and methods of use |
| TW202233187A (zh) | 2020-11-04 | 2022-09-01 | 日商衛材R&D企管股份有限公司 | 骨髓發育不良症候群(mds)之生物標記物及其使用方法 |
| WO2023131866A1 (en) | 2022-01-05 | 2023-07-13 | Eisai R&D Management Co., Ltd. | Biomarkers for myelodysplastic syndrome (mds) and methods of using the same |
| JP2025517430A (ja) * | 2022-05-20 | 2025-06-05 | ノバルティス アーゲー | Epha2 bcl-xl阻害剤抗体-薬物コンジュゲートおよびその使用の方法 |
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