PE20190398A1 - Anticuerpos nuevos que se unen especificamente a los epitopos del virus del zika y usos de los mismos - Google Patents

Anticuerpos nuevos que se unen especificamente a los epitopos del virus del zika y usos de los mismos

Info

Publication number
PE20190398A1
PE20190398A1 PE2019000034A PE2019000034A PE20190398A1 PE 20190398 A1 PE20190398 A1 PE 20190398A1 PE 2019000034 A PE2019000034 A PE 2019000034A PE 2019000034 A PE2019000034 A PE 2019000034A PE 20190398 A1 PE20190398 A1 PE 20190398A1
Authority
PE
Peru
Prior art keywords
zika virus
specifically bind
epithopes
zika
antibody
Prior art date
Application number
PE2019000034A
Other languages
English (en)
Spanish (es)
Inventor
Davide Corti
Original Assignee
Humabs Biomed Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Humabs Biomed Sa filed Critical Humabs Biomed Sa
Publication of PE20190398A1 publication Critical patent/PE20190398A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PE2019000034A 2016-07-13 2017-07-12 Anticuerpos nuevos que se unen especificamente a los epitopos del virus del zika y usos de los mismos PE20190398A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2016/066684 WO2018010789A1 (en) 2016-07-13 2016-07-13 Novel antibodies specifically binding to zika virus epitopes and uses thereof

Publications (1)

Publication Number Publication Date
PE20190398A1 true PE20190398A1 (es) 2019-03-13

Family

ID=56413654

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2019000034A PE20190398A1 (es) 2016-07-13 2017-07-12 Anticuerpos nuevos que se unen especificamente a los epitopos del virus del zika y usos de los mismos

Country Status (31)

Country Link
US (3) US11117954B2 (enExample)
EP (2) EP3484915B1 (enExample)
JP (2) JP7252888B2 (enExample)
KR (1) KR102595764B1 (enExample)
CN (2) CN116199775A (enExample)
AU (1) AU2017297757B2 (enExample)
BR (1) BR112018074456A2 (enExample)
CA (1) CA3024374A1 (enExample)
CL (2) CL2019000067A1 (enExample)
CO (1) CO2019001111A2 (enExample)
CR (1) CR20190066A (enExample)
DK (1) DK3484915T5 (enExample)
DO (2) DOP2019000006A (enExample)
EA (1) EA201990243A1 (enExample)
EC (1) ECSP19009170A (enExample)
ES (1) ES2959883T3 (enExample)
FI (1) FI3484915T3 (enExample)
HR (1) HRP20231196T1 (enExample)
HU (1) HUE063272T2 (enExample)
IL (1) IL262710B2 (enExample)
LT (1) LT3484915T (enExample)
MX (1) MX2019000526A (enExample)
MY (1) MY190553A (enExample)
PE (1) PE20190398A1 (enExample)
PH (1) PH12018502348B1 (enExample)
PL (1) PL3484915T3 (enExample)
SG (1) SG11201809879WA (enExample)
SI (1) SI3484915T1 (enExample)
UA (1) UA126381C2 (enExample)
WO (2) WO2018010789A1 (enExample)
ZA (1) ZA201807467B (enExample)

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CA3040189A1 (en) 2016-10-13 2018-04-19 Massachusetts Institute Of Technology Antibodies that bind zika virus envelope protein and uses thereof
WO2019042555A1 (en) 2017-08-31 2019-03-07 Humabs Biomed Sa MULTISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO ZIKA VIRUS EPITOPES AND USES THEREOF
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
JP2019152666A (ja) * 2018-03-02 2019-09-12 富士レビオ株式会社 ジカウイルスを検出する方法及びキット
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WO2019219443A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
WO2020061159A1 (en) * 2018-09-20 2020-03-26 Vanderbilt University Human antibodies to zika virus
WO2020078568A1 (en) 2018-10-19 2020-04-23 Humabs Biomed Sa Antibodies and methods for treatment of lyssavirus infection
WO2020092564A1 (en) * 2018-10-31 2020-05-07 Icahn School Of Medicine At Mount Sinai Human antibodies targeting zika virus ns1, ns1 polypeptides and uses thereof
JP7463366B2 (ja) * 2018-11-20 2024-04-08 タケダ ワクチン,インコーポレイテッド 新規の抗ジカウイルス抗体及びその使用
WO2020245663A1 (en) * 2019-06-01 2020-12-10 Institut Pasteur Nanobody-based ns1 assay for the specific diagnosis of acute zika virus infection
US12570725B2 (en) 2019-09-13 2026-03-10 Duke University ZIKA antibodies and their use
JP7725465B2 (ja) * 2019-11-07 2025-08-19 中国科学院微生物研究所 ジカ・デングワクチン及びその使用
WO2021101739A1 (en) * 2019-11-19 2021-05-27 Vanderbilt University Human antibodies that neutralize zika virus and methods of use therefor
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CN111100201B (zh) * 2019-12-31 2021-09-28 武汉班科生物技术股份有限公司 针对寨卡病毒囊膜蛋白的鼠源单克隆抗体
JP7471555B2 (ja) * 2020-02-20 2024-04-22 国立感染症研究所長 フラビウイルス交差中和抗体及び医薬組成物
US20230324404A1 (en) 2020-05-20 2023-10-12 Takeda Vaccines, Inc. Method for detection of zika virus specific antibodies
WO2021236225A1 (en) 2020-05-20 2021-11-25 Takeda Vaccines, Inc. Method for detection of zika virus specific antibodies
JP2023527169A (ja) 2020-05-20 2023-06-27 タケダ ワクチン,インコーポレイテッド 抗原の効力を決定するための方法
CN115697392B (zh) * 2020-06-28 2026-03-13 神州细胞工程有限公司 一种降低病毒ade效应的方法
US20240180969A1 (en) * 2021-04-01 2024-06-06 A2 Biotherapeutics, Inc. Polypeptides targeting hla-a*11 and methods of use thereof
CN112921124B (zh) * 2021-04-08 2021-09-28 广东创晟控股集团有限公司 一种快速检测病毒的试剂盒
WO2024211789A1 (en) * 2023-04-07 2024-10-10 Fred Hutchinson Cancer Center Cross-flavivirus binding domains and uses thereof

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Also Published As

Publication number Publication date
EP3484915B1 (en) 2023-08-16
DOP2019000006A (es) 2019-03-31
WO2018011283A1 (en) 2018-01-18
MX2019000526A (es) 2019-05-02
US20190256582A1 (en) 2019-08-22
LT3484915T (lt) 2023-10-10
DK3484915T5 (da) 2024-09-02
KR102595764B1 (ko) 2023-10-30
DK3484915T3 (da) 2023-10-09
IL262710B1 (en) 2024-01-01
US20210363227A1 (en) 2021-11-25
DOP2021000026A (es) 2021-07-30
CA3024374A1 (en) 2018-01-18
JP7252888B2 (ja) 2023-04-05
PL3484915T3 (pl) 2024-03-25
FI3484915T3 (fi) 2023-11-15
BR112018074456A2 (pt) 2019-03-19
CL2021002994A1 (es) 2022-09-09
ES2959883T3 (es) 2024-02-28
US20210355198A1 (en) 2021-11-18
US11117954B2 (en) 2021-09-14
CL2019000067A1 (es) 2019-07-26
CO2019001111A2 (es) 2019-08-20
WO2018010789A1 (en) 2018-01-18
UA126381C2 (uk) 2022-09-28
SI3484915T1 (sl) 2024-02-29
AU2017297757A1 (en) 2018-11-22
EP3484915A1 (en) 2019-05-22
KR20190027382A (ko) 2019-03-14
PH12018502348A1 (en) 2019-03-25
CN116199775A (zh) 2023-06-02
PH12018502348B1 (en) 2024-02-28
CR20190066A (es) 2019-09-10
AU2017297757B2 (en) 2024-06-13
ZA201807467B (en) 2024-04-24
ECSP19009170A (es) 2019-02-28
CN109563157B (zh) 2023-01-17
SG11201809879WA (en) 2018-12-28
EP4342911A1 (en) 2024-03-27
IL262710B2 (en) 2024-05-01
CN109563157A (zh) 2019-04-02
HUE063272T2 (hu) 2024-01-28
US11912757B2 (en) 2024-02-27
HRP20231196T1 (hr) 2024-01-19
JP2019533425A (ja) 2019-11-21
JP2023062036A (ja) 2023-05-02
MY190553A (en) 2022-04-27
IL262710A (en) 2018-12-31
EA201990243A1 (ru) 2019-07-31

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