CO2019001111A2 - Anticuerpos nuevos que se unen específicamente a los epítopos del virus del zika y usos de los mismos - Google Patents

Anticuerpos nuevos que se unen específicamente a los epítopos del virus del zika y usos de los mismos

Info

Publication number
CO2019001111A2
CO2019001111A2 CONC2019/0001111A CO2019001111A CO2019001111A2 CO 2019001111 A2 CO2019001111 A2 CO 2019001111A2 CO 2019001111 A CO2019001111 A CO 2019001111A CO 2019001111 A2 CO2019001111 A2 CO 2019001111A2
Authority
CO
Colombia
Prior art keywords
antibodies
zika virus
specifically bind
new antibodies
relates
Prior art date
Application number
CONC2019/0001111A
Other languages
English (en)
Spanish (es)
Inventor
Davide Corti
Original Assignee
Humabs Biomed Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Humabs Biomed Sa filed Critical Humabs Biomed Sa
Publication of CO2019001111A2 publication Critical patent/CO2019001111A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CONC2019/0001111A 2016-07-13 2019-02-05 Anticuerpos nuevos que se unen específicamente a los epítopos del virus del zika y usos de los mismos CO2019001111A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2016/066684 WO2018010789A1 (en) 2016-07-13 2016-07-13 Novel antibodies specifically binding to zika virus epitopes and uses thereof
PCT/EP2017/067581 WO2018011283A1 (en) 2016-07-13 2017-07-12 Novel antibodies specifically binding to zika virus epitopes and uses thereof

Publications (1)

Publication Number Publication Date
CO2019001111A2 true CO2019001111A2 (es) 2019-08-20

Family

ID=56413654

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2019/0001111A CO2019001111A2 (es) 2016-07-13 2019-02-05 Anticuerpos nuevos que se unen específicamente a los epítopos del virus del zika y usos de los mismos

Country Status (31)

Country Link
US (3) US11117954B2 (enExample)
EP (2) EP3484915B1 (enExample)
JP (2) JP7252888B2 (enExample)
KR (1) KR102595764B1 (enExample)
CN (2) CN116199775A (enExample)
AU (1) AU2017297757B2 (enExample)
BR (1) BR112018074456A2 (enExample)
CA (1) CA3024374A1 (enExample)
CL (2) CL2019000067A1 (enExample)
CO (1) CO2019001111A2 (enExample)
CR (1) CR20190066A (enExample)
DK (1) DK3484915T5 (enExample)
DO (2) DOP2019000006A (enExample)
EA (1) EA201990243A1 (enExample)
EC (1) ECSP19009170A (enExample)
ES (1) ES2959883T3 (enExample)
FI (1) FI3484915T3 (enExample)
HR (1) HRP20231196T1 (enExample)
HU (1) HUE063272T2 (enExample)
IL (1) IL262710B2 (enExample)
LT (1) LT3484915T (enExample)
MX (1) MX2019000526A (enExample)
MY (1) MY190553A (enExample)
PE (1) PE20190398A1 (enExample)
PH (1) PH12018502348B1 (enExample)
PL (1) PL3484915T3 (enExample)
SG (1) SG11201809879WA (enExample)
SI (1) SI3484915T1 (enExample)
UA (1) UA126381C2 (enExample)
WO (2) WO2018010789A1 (enExample)
ZA (1) ZA201807467B (enExample)

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CA3040189A1 (en) 2016-10-13 2018-04-19 Massachusetts Institute Of Technology Antibodies that bind zika virus envelope protein and uses thereof
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WO2019219443A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
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JP7463366B2 (ja) * 2018-11-20 2024-04-08 タケダ ワクチン,インコーポレイテッド 新規の抗ジカウイルス抗体及びその使用
WO2020245663A1 (en) * 2019-06-01 2020-12-10 Institut Pasteur Nanobody-based ns1 assay for the specific diagnosis of acute zika virus infection
US12570725B2 (en) 2019-09-13 2026-03-10 Duke University ZIKA antibodies and their use
JP7725465B2 (ja) * 2019-11-07 2025-08-19 中国科学院微生物研究所 ジカ・デングワクチン及びその使用
WO2021101739A1 (en) * 2019-11-19 2021-05-27 Vanderbilt University Human antibodies that neutralize zika virus and methods of use therefor
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JP2023527169A (ja) 2020-05-20 2023-06-27 タケダ ワクチン,インコーポレイテッド 抗原の効力を決定するための方法
CN115697392B (zh) * 2020-06-28 2026-03-13 神州细胞工程有限公司 一种降低病毒ade效应的方法
US20240180969A1 (en) * 2021-04-01 2024-06-06 A2 Biotherapeutics, Inc. Polypeptides targeting hla-a*11 and methods of use thereof
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Also Published As

Publication number Publication date
EP3484915B1 (en) 2023-08-16
DOP2019000006A (es) 2019-03-31
WO2018011283A1 (en) 2018-01-18
MX2019000526A (es) 2019-05-02
PE20190398A1 (es) 2019-03-13
US20190256582A1 (en) 2019-08-22
LT3484915T (lt) 2023-10-10
DK3484915T5 (da) 2024-09-02
KR102595764B1 (ko) 2023-10-30
DK3484915T3 (da) 2023-10-09
IL262710B1 (en) 2024-01-01
US20210363227A1 (en) 2021-11-25
DOP2021000026A (es) 2021-07-30
CA3024374A1 (en) 2018-01-18
JP7252888B2 (ja) 2023-04-05
PL3484915T3 (pl) 2024-03-25
FI3484915T3 (fi) 2023-11-15
BR112018074456A2 (pt) 2019-03-19
CL2021002994A1 (es) 2022-09-09
ES2959883T3 (es) 2024-02-28
US20210355198A1 (en) 2021-11-18
US11117954B2 (en) 2021-09-14
CL2019000067A1 (es) 2019-07-26
WO2018010789A1 (en) 2018-01-18
UA126381C2 (uk) 2022-09-28
SI3484915T1 (sl) 2024-02-29
AU2017297757A1 (en) 2018-11-22
EP3484915A1 (en) 2019-05-22
KR20190027382A (ko) 2019-03-14
PH12018502348A1 (en) 2019-03-25
CN116199775A (zh) 2023-06-02
PH12018502348B1 (en) 2024-02-28
CR20190066A (es) 2019-09-10
AU2017297757B2 (en) 2024-06-13
ZA201807467B (en) 2024-04-24
ECSP19009170A (es) 2019-02-28
CN109563157B (zh) 2023-01-17
SG11201809879WA (en) 2018-12-28
EP4342911A1 (en) 2024-03-27
IL262710B2 (en) 2024-05-01
CN109563157A (zh) 2019-04-02
HUE063272T2 (hu) 2024-01-28
US11912757B2 (en) 2024-02-27
HRP20231196T1 (hr) 2024-01-19
JP2019533425A (ja) 2019-11-21
JP2023062036A (ja) 2023-05-02
MY190553A (en) 2022-04-27
IL262710A (en) 2018-12-31
EA201990243A1 (ru) 2019-07-31

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