PE20160531A1 - Combinacion farmaceutica - Google Patents

Combinacion farmaceutica

Info

Publication number
PE20160531A1
PE20160531A1 PE2016000337A PE2016000337A PE20160531A1 PE 20160531 A1 PE20160531 A1 PE 20160531A1 PE 2016000337 A PE2016000337 A PE 2016000337A PE 2016000337 A PE2016000337 A PE 2016000337A PE 20160531 A1 PE20160531 A1 PE 20160531A1
Authority
PE
Peru
Prior art keywords
components
administered
combination
mammal
component
Prior art date
Application number
PE2016000337A
Other languages
English (en)
Inventor
Petra Blomsfunke
Klaus Schiene
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42395008&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20160531(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of PE20160531A1 publication Critical patent/PE20160531A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se refiere a una combinacion que comprende a modo de componentes, (a) por lo menos un compuesto 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol, y (b) por lo menos un antagonista de NMDA, una formulacion farmaceutica y una forma de dosificacion que comprende dicha combinacion, asi como un metodo de tratamiento del dolor, por ejemplo dolor inflamatorio o dolor neuropatico, en la que los componentes (a) y (b) se administran simultaneamente o secuencialmente en un mamifero, de manera que el componente (a) puede administrarse antes o despues del componente (b) y de manera que los componentes (a) o (b) se administran en el mamifero mediante la misma via de administracion o vias diferentes.
PE2016000337A 2010-06-15 2011-06-14 Combinacion farmaceutica PE20160531A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10006202 2010-06-15

Publications (1)

Publication Number Publication Date
PE20160531A1 true PE20160531A1 (es) 2016-06-05

Family

ID=42395008

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2012002241A PE20130243A1 (es) 2010-06-15 2011-06-14 Combinacion farmaceutica
PE2016000337A PE20160531A1 (es) 2010-06-15 2011-06-14 Combinacion farmaceutica

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2012002241A PE20130243A1 (es) 2010-06-15 2011-06-14 Combinacion farmaceutica

Country Status (29)

Country Link
US (3) US8846765B2 (es)
EP (2) EP2992877A1 (es)
JP (3) JP6133772B2 (es)
KR (1) KR101831616B1 (es)
CN (1) CN103108631B (es)
AR (1) AR081931A1 (es)
AU (2) AU2011267474B2 (es)
BR (1) BR112012031836A2 (es)
CA (1) CA2796774C (es)
CL (1) CL2012002551A1 (es)
CO (1) CO6602157A2 (es)
CY (1) CY1117118T1 (es)
DK (1) DK2582366T3 (es)
EC (2) ECSP12012217A (es)
ES (1) ES2560676T3 (es)
HK (2) HK1215787A1 (es)
HR (1) HRP20151327T1 (es)
HU (1) HUE026619T2 (es)
IL (1) IL221926A (es)
MX (1) MX2012014482A (es)
NZ (1) NZ602625A (es)
PE (2) PE20130243A1 (es)
PL (1) PL2582366T3 (es)
PT (1) PT2582366E (es)
RS (1) RS54439B1 (es)
RU (2) RU2589692C2 (es)
SI (1) SI2582366T1 (es)
WO (1) WO2011157391A1 (es)
ZA (1) ZA201208646B (es)

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US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
US20130236573A1 (en) * 2012-03-12 2013-09-12 Janssen Pharmaceutica Nv Esketamine for the treatment of treatment-refractory or treatment-resistant depression
WO2014116739A1 (en) * 2013-01-22 2014-07-31 Vistagen Therapeutics, Inc. Dosage forms and therapeutic uses l-4-chlorokynurenine
CN111643449A (zh) 2013-03-15 2020-09-11 詹森药业有限公司 S-盐酸氯胺酮的药物组合物
CN103655523A (zh) * 2013-12-24 2014-03-26 南京艾德凯腾生物医药有限责任公司 他喷他多组合物
AU2015256075B2 (en) * 2014-05-06 2021-02-25 Northwestern University Combinations of NMDAR modulating compounds
JP6545788B2 (ja) 2014-08-13 2019-07-17 ヤンセン ファーマシューティカ エヌ.ベー. うつ病の治療方法
EP3725307A1 (en) 2014-09-15 2020-10-21 Janssen Pharmaceutica NV Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
EP3297620A4 (en) 2015-06-27 2019-01-09 Shenox Pharmaceuticals, LLC TRANSDERMAL DELIVERY SYSTEM FOR KETAMINE
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
SG11202005896WA (en) 2017-12-22 2020-07-29 Janssen Pharmaceuticals Inc Esketamine for the treatment of depression
CA3096671A1 (en) * 2018-04-12 2019-10-17 Anavex Life Sciences Corp. A2-73 crystalline polymorph compositions of matter and methods of use thereof
MX2021010683A (es) 2019-03-05 2021-12-10 Janssen Pharmaceuticals Inc Esketamina para el tratamiento de la depresión.

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Also Published As

Publication number Publication date
JP6197007B2 (ja) 2017-09-13
JP6423036B2 (ja) 2018-11-14
ECSP12012217A (es) 2012-11-30
RU2013101515A (ru) 2014-07-20
IL221926A (en) 2015-08-31
BR112012031836A2 (pt) 2016-11-08
RS54439B1 (en) 2016-06-30
SI2582366T1 (sl) 2016-02-29
US20110306674A1 (en) 2011-12-15
HUE026619T2 (en) 2016-06-28
AU2011267474A1 (en) 2013-01-10
EP2582366B1 (en) 2015-10-28
DK2582366T3 (en) 2015-12-07
PT2582366E (pt) 2016-01-26
WO2011157391A1 (en) 2011-12-22
MX2012014482A (es) 2013-02-21
PE20130243A1 (es) 2013-03-22
HK1215787A1 (zh) 2016-09-15
CL2012002551A1 (es) 2012-11-09
CO6602157A2 (es) 2013-01-18
CA2796774C (en) 2020-06-02
CA2796774A1 (en) 2011-12-22
AU2016219643B2 (en) 2018-04-12
EP2992877A1 (en) 2016-03-09
US10813890B2 (en) 2020-10-27
ZA201208646B (en) 2013-09-25
HK1184370A1 (zh) 2014-01-24
US20140309311A1 (en) 2014-10-16
CY1117118T1 (el) 2017-04-05
KR101831616B1 (ko) 2018-04-04
ES2560676T3 (es) 2016-02-22
JP2015232015A (ja) 2015-12-24
AR081931A1 (es) 2012-10-31
AU2016219643A1 (en) 2016-09-15
ECSP19047259A (es) 2019-07-31
RU2589692C2 (ru) 2016-07-10
NZ602625A (en) 2014-03-28
CN103108631B (zh) 2015-08-26
JP6133772B2 (ja) 2017-05-24
AU2011267474B2 (en) 2016-05-26
EP2582366A1 (en) 2013-04-24
RU2016119041A (ru) 2017-11-20
CN103108631A (zh) 2013-05-15
US8846765B2 (en) 2014-09-30
RU2675261C2 (ru) 2018-12-18
US20170333369A1 (en) 2017-11-23
JP2013528629A (ja) 2013-07-11
PL2582366T3 (pl) 2016-04-29
JP2017141277A (ja) 2017-08-17
KR20130111945A (ko) 2013-10-11
HRP20151327T1 (hr) 2016-01-01

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