PL2735338T3 - Farmaceutyczne skojarzenie 3-(3-dimetyloamino-1-etylo-2-metylopropylo)-fenolu i pregabaliny lub gabapentyny - Google Patents

Farmaceutyczne skojarzenie 3-(3-dimetyloamino-1-etylo-2-metylopropylo)-fenolu i pregabaliny lub gabapentyny

Info

Publication number
PL2735338T3
PL2735338T3 PL14000597T PL14000597T PL2735338T3 PL 2735338 T3 PL2735338 T3 PL 2735338T3 PL 14000597 T PL14000597 T PL 14000597T PL 14000597 T PL14000597 T PL 14000597T PL 2735338 T3 PL2735338 T3 PL 2735338T3
Authority
PL
Poland
Prior art keywords
pregabalin
gabapentin
dimethylamino
phenol
propyl
Prior art date
Application number
PL14000597T
Other languages
English (en)
Inventor
Klaus Schiene
Petra Bloms-Funke
Thomas Christoph
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40345058&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2735338(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of PL2735338T3 publication Critical patent/PL2735338T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PL14000597T 2008-09-05 2009-09-04 Farmaceutyczne skojarzenie 3-(3-dimetyloamino-1-etylo-2-metylopropylo)-fenolu i pregabaliny lub gabapentyny PL2735338T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08015625 2008-09-05
EP09778335.1A EP2331210B1 (en) 2008-09-05 2009-09-04 Pharmaceutical combination of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol and an antiepileptic
PCT/EP2009/006424 WO2010025931A2 (en) 2008-09-05 2009-09-04 Pharmaceutical combination
EP14000597.6A EP2735338B1 (en) 2008-09-05 2009-09-04 Pharmaceutical combination of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol and pregabalin or gabapentin

Publications (1)

Publication Number Publication Date
PL2735338T3 true PL2735338T3 (pl) 2019-07-31

Family

ID=40345058

Family Applications (2)

Application Number Title Priority Date Filing Date
PL14000597T PL2735338T3 (pl) 2008-09-05 2009-09-04 Farmaceutyczne skojarzenie 3-(3-dimetyloamino-1-etylo-2-metylopropylo)-fenolu i pregabaliny lub gabapentyny
PL09778335T PL2331210T3 (pl) 2008-09-05 2009-09-04 Kombinacja farmaceutyczna 3-(3-dimetyloamino-1-etylo-2-metylo-propylo)-fenolu i środka przeciwpadaczkowego

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL09778335T PL2331210T3 (pl) 2008-09-05 2009-09-04 Kombinacja farmaceutyczna 3-(3-dimetyloamino-1-etylo-2-metylo-propylo)-fenolu i środka przeciwpadaczkowego

Country Status (28)

Country Link
US (1) US20100063148A1 (pl)
EP (2) EP2735338B1 (pl)
JP (4) JP5731387B2 (pl)
KR (3) KR101730924B1 (pl)
CN (2) CN102159284B (pl)
AR (2) AR073361A1 (pl)
AU (3) AU2009289776A1 (pl)
BR (1) BRPI0920521A2 (pl)
CA (1) CA2735857C (pl)
CL (1) CL2011000317A1 (pl)
CO (1) CO6382142A2 (pl)
CY (2) CY1115751T1 (pl)
DK (2) DK2331210T3 (pl)
EC (1) ECSP11010869A (pl)
ES (2) ES2513394T3 (pl)
HR (2) HRP20140663T1 (pl)
HU (1) HUE043278T2 (pl)
IL (3) IL211135A (pl)
LT (1) LT2735338T (pl)
MX (1) MX2011002339A (pl)
PE (5) PE20190914A1 (pl)
PL (2) PL2735338T3 (pl)
PT (2) PT2331210E (pl)
RU (2) RU2674150C1 (pl)
SI (2) SI2331210T1 (pl)
TR (1) TR201904388T4 (pl)
WO (1) WO2010025931A2 (pl)
ZA (1) ZA201101449B (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
EP2462990B2 (en) 2006-06-15 2018-04-18 UCB Pharma GmbH Pharmaceutical composition comprising lacosamide and levetiracetam with synergistic anticonvulsant effect
RU2674150C1 (ru) * 2008-09-05 2018-12-05 Грюненталь Гмбх Фармацевтическая комбинация
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
FR2943246B1 (fr) * 2009-03-19 2011-07-29 Biocodex Compose pour son utilisation dans le traitement des neuropathies peripheriques
EP2582366B1 (en) 2010-06-15 2015-10-28 Grünenthal GmbH Pharmaceutical combination for the treatment of pain
AU2011276170B2 (en) 2010-07-06 2016-03-10 Grunenthal Gmbh Novel gastro- retentive dosage forms comprising a GABA Analog and an opioid
RU2544552C2 (ru) 2010-07-30 2015-03-20 Торэй Индастриз, Инк. Терапевтическое средство или профилактическое средство для нейропатической боли
CN103501775A (zh) * 2011-03-04 2014-01-08 格吕伦塔尔有限公司 他喷他多的胃肠外给药
EP2753302B1 (en) * 2011-07-20 2018-11-28 Torrent Pharmaceuticals Ltd. Pharmaceutical composition of tapentadol
TR201802128T4 (tr) * 2011-07-29 2018-03-21 Gruenenthal Gmbh İntratekal veya epidural yolla 3-[(1s,2s)-3-(dimetilamino)-1-etil-2-metilpropil]fenol uygulaması.
US9320725B2 (en) * 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
US8912226B2 (en) * 2012-05-18 2014-12-16 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
US9320729B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
US9855286B2 (en) 2012-05-18 2018-01-02 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US20130310435A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and Paracetamol or Propacetamol
US9345689B2 (en) * 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US9308196B2 (en) * 2012-05-18 2016-04-12 Gruenenthal Gmbh Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
KR20150075408A (ko) * 2012-11-01 2015-07-03 토렌트 파마슈티칼스 리미티드 비경구용 타펜타돌의 약학 조성물
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
US9549909B2 (en) 2013-05-03 2017-01-24 The Katholieke Universiteit Leuven Method for the treatment of dravet syndrome
CN103655523A (zh) * 2013-12-24 2014-03-26 南京艾德凯腾生物医药有限责任公司 他喷他多组合物
WO2017112701A1 (en) 2015-12-22 2017-06-29 Zogenix International Limited Metabolism resistant fenfluramine analogs and methods of using the same
HRP20250898T1 (hr) 2015-12-22 2025-09-26 Zogenix International Limited Pripravci fenfluramina i postupci njihove pripreme
JP2019526544A (ja) 2016-08-24 2019-09-19 ゾゲニクス インターナショナル リミテッド 5−ht2bアゴニストの形成を阻害するための製剤およびその使用方法
US10682317B2 (en) 2017-09-26 2020-06-16 Zogenix International Limited Ketogenic diet compatible fenfluramine formulation
KR20190081385A (ko) 2017-12-29 2019-07-09 강원대학교산학협력단 옥스카바제핀을 유효성분으로 함유하는 허혈성 뇌혈관 질환 예방용 조성물
WO2019216919A1 (en) 2018-05-11 2019-11-14 Zogenix International Limited Compositions and methods for treating seizure-induced sudden death
SG11202104378SA (en) 2018-11-19 2021-05-28 Zogenix International Ltd Methods of treating rett syndrome using fenfluramine
US11612574B2 (en) 2020-07-17 2023-03-28 Zogenix International Limited Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US5472711A (en) 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
US5330761A (en) 1993-01-29 1994-07-19 Edward Mendell Co. Inc. Bioadhesive tablet for non-systemic use products
US5455046A (en) 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5399362A (en) 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
US6562865B1 (en) * 1999-08-20 2003-05-13 Ortho-Mcneil Pharmaceutical, Inc. Composition comprising a tramadol material and an anticonvulsant drug
EP1471909A4 (en) * 2002-01-16 2007-07-25 Endo Pharmaceuticals Inc PHARMACEUTICAL COMPOSITION AND METHOD FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM
IL162932A0 (en) * 2002-02-22 2005-11-20 Warner Lambert Co Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2
WO2007005716A2 (en) * 2005-06-30 2007-01-11 Cinergen, Llc Methods of treatment and compositions for use thereof
US20090082466A1 (en) * 2006-01-27 2009-03-26 Najib Babul Abuse Resistant and Extended Release Formulations and Method of Use Thereof
RU2465263C2 (ru) * 2006-04-28 2012-10-27 Грюненталь Гмбх Фармацевтическая комбинация, включающая 3-(3-диметиламино-1-этил-2-метилпропил)фенол и нестероидный противовоспалительный препарат
WO2008027442A2 (en) * 2006-08-30 2008-03-06 Theraquest Biosciences, Llc Abuse deterrent oral pharmaceutical formulations of opioid agonists and method of use
PL2596784T3 (pl) * 2007-11-23 2017-06-30 Grünenthal GmbH Kompozycje tapentadolu
CA2710538A1 (en) * 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of a (3s)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
RU2674150C1 (ru) * 2008-09-05 2018-12-05 Грюненталь Гмбх Фармацевтическая комбинация

Also Published As

Publication number Publication date
CN102159284B (zh) 2015-12-09
CL2011000317A1 (es) 2011-06-17
KR20160086981A (ko) 2016-07-20
HRP20190500T1 (hr) 2019-08-09
DK2331210T3 (da) 2014-08-11
AU2009289776A1 (en) 2010-03-11
JP2015096530A (ja) 2015-05-21
JP2012501986A (ja) 2012-01-26
AR117613A2 (es) 2021-08-18
WO2010025931A2 (en) 2010-03-11
AU2018202879A1 (en) 2018-05-17
HRP20140663T1 (hr) 2014-10-10
PE20142371A1 (es) 2015-02-04
MX2011002339A (es) 2011-04-04
EP2735338A1 (en) 2014-05-28
ECSP11010869A (es) 2011-04-29
HUE043278T2 (hu) 2019-08-28
JP2017071636A (ja) 2017-04-13
RU2674150C1 (ru) 2018-12-05
JP5731387B2 (ja) 2015-06-10
CN105520924A (zh) 2016-04-27
SI2331210T1 (sl) 2014-10-30
CN102159284A (zh) 2011-08-17
KR20170048602A (ko) 2017-05-08
PE20190914A1 (es) 2019-06-26
KR101641519B1 (ko) 2016-07-21
US20100063148A1 (en) 2010-03-11
KR20110057144A (ko) 2011-05-31
KR101730924B1 (ko) 2017-04-27
PT2735338T (pt) 2019-05-24
RU2571501C2 (ru) 2015-12-20
CY1115751T1 (el) 2017-01-25
PL2331210T3 (pl) 2014-12-31
IL237392B (en) 2019-08-29
AU2016203053A1 (en) 2016-06-02
KR101851120B1 (ko) 2018-04-23
LT2735338T (lt) 2019-04-10
TR201904388T4 (tr) 2019-05-21
PE20142372A1 (es) 2015-02-04
PT2331210E (pt) 2014-08-25
IL237391A (en) 2017-12-31
SI2735338T1 (sl) 2019-04-30
ZA201101449B (en) 2011-10-26
ES2513394T3 (es) 2014-10-27
CA2735857C (en) 2019-05-28
AU2018202879B2 (en) 2020-03-12
AU2016203053B2 (en) 2018-01-25
BRPI0920521A2 (pt) 2018-01-16
IL211135A (en) 2017-09-28
ES2719900T3 (es) 2019-07-16
HK1198145A1 (en) 2015-03-13
HK1159011A1 (en) 2012-07-27
WO2010025931A3 (en) 2010-06-17
PE20142357A1 (es) 2015-02-04
EP2331210B1 (en) 2014-07-09
CA2735857A1 (en) 2010-03-11
PE20110291A1 (es) 2011-06-04
JP2019131578A (ja) 2019-08-08
AR073361A1 (es) 2010-11-03
RU2011112444A (ru) 2012-10-10
DK2735338T3 (en) 2019-04-23
EP2331210A2 (en) 2011-06-15
IL237391A0 (en) 2015-04-30
IL237392A0 (en) 2015-04-30
IL211135A0 (en) 2011-04-28
EP2735338B1 (en) 2019-02-06
CO6382142A2 (es) 2012-02-15
CN105520924B (zh) 2019-04-09
CY1121492T1 (el) 2020-05-29

Similar Documents

Publication Publication Date Title
LT2735338T (lt) 3-(3-dimetilamino-1-etil-2-metil-propil)-fenolio ir pregabalino arba gabapentino farmacinis derinys
HUS000504I2 (hu) Relebaktám, adott esetben monohidrát formájában, és imipenem kombinációja
ZA201102762B (en) CO-CRYSTALS OF TRAMADOL AND NSAIDs
EP2445340A4 (en) SUBSTITUTED HYDROXAMINE ACIDS AND USES THEREOF
BRPI0909750A2 (pt) dispositivo e cápsula para a preparação de uma bebida
IL210318A (en) Acetylation fatty acid salicylates and their uses
GB201013420D0 (en) Slowness-frequency projection display and animation
PL2519100T3 (pl) Związki pośrednie i sposoby wytwarzania tapentadolu i pokrewnych związków
PL2474522T3 (pl) Agomelatyna i jej kompozycje farmaceutyczne
ZA201202151B (en) Compositions comprising tramadol and celecoxib in the treatment of pain
IL200514A0 (en) Solid forms comprising (-) o-desmethylvenlafaxine and uses thereof
EP2358658A4 (en) PREPARATION OF RASAGILIN AND ITS SALTS
ZA200905688B (en) Fungicidal mixtures of 1-Methylpyrazole-4-Ylcarboxylic acid anilides and azolopy-rimidinylamines
IL214355A0 (en) Antibodies against human tweak and uses thereof
IL207508A0 (en) Dosage forms comprising gabapentin and a hydrophillic polymer and uses thereof
IL209698A (en) Use of Niportimox for the preparation of pharmaceuticals and preparations containing this Niportimox
PT2117519E (pt) Composição farmaceutica compreendendo tramadol e cetoprofeno
IL213711A0 (en) Pharmaceuticl formulation of nanonised fenofibrate
ZA201101669B (en) Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3 diol and paracetamol
GB0819293D0 (en) Radiofluorination
IL206555A (en) Array decoder
HK1160035A (en) Co-crystals of tramadol and nsaids
HU0800091D0 (en) Novel polymorphs and amorph forms of desvenlafaxine fumarate
HU0900062D0 (en) Novel polymorphs and amorph forms of desvenlafaxine fumarate