PE20130496A1 - Tratamiento de artritis por lupus usando laquinimod - Google Patents
Tratamiento de artritis por lupus usando laquinimodInfo
- Publication number
- PE20130496A1 PE20130496A1 PE2012001382A PE2012001382A PE20130496A1 PE 20130496 A1 PE20130496 A1 PE 20130496A1 PE 2012001382 A PE2012001382 A PE 2012001382A PE 2012001382 A PE2012001382 A PE 2012001382A PE 20130496 A1 PE20130496 A1 PE 20130496A1
- Authority
- PE
- Peru
- Prior art keywords
- laquinimod
- lupus arthritis
- arthritis treatment
- treatment
- active lupus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
SE REFIERE A UN METODO DE TRATAMIENTO DE ARTRITIS POR LUPUS ACTIVO CON LAQUINIMOD QUE CONSISTE EN ADMINISTRAR PERIODICAMENTE POR AL MENOS 12 SEMANAS UNA CANTIDAD DE 0.5-1.0 mg/dia DE LAQUINIMOD SODICO EN FORMA ORAL, CONJUNTAMENTE CON CORTICOIDES, INMUNOSUPRESORES, FARMACOS ANTIPALUDICOS, ENTRE OTROS. REFERIDA ADEMAS A UNA COMPOSICION FARMACEUTICA. DICHO METODO REDUCE LOS SINTOMAS DE ARTRITIS POR LUPUS ACTIVO COMO HINCHAZON DE ARTICULACIONES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33935510P | 2010-03-03 | 2010-03-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20130496A1 true PE20130496A1 (es) | 2013-05-08 |
Family
ID=44531530
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2012001382A PE20130496A1 (es) | 2010-03-03 | 2011-03-02 | Tratamiento de artritis por lupus usando laquinimod |
Country Status (21)
Country | Link |
---|---|
US (4) | US20110217295A1 (es) |
EP (1) | EP2542080B1 (es) |
JP (2) | JP2013521305A (es) |
KR (1) | KR20130036217A (es) |
CN (1) | CN102781239B (es) |
AU (1) | AU2011223702B2 (es) |
BR (1) | BR112012022064A2 (es) |
CA (1) | CA2791711A1 (es) |
CL (1) | CL2012002422A1 (es) |
CO (1) | CO6630086A2 (es) |
EA (1) | EA201290859A1 (es) |
ES (1) | ES2601819T3 (es) |
HK (1) | HK1177876A1 (es) |
MX (1) | MX342001B (es) |
NZ (1) | NZ602512A (es) |
PE (1) | PE20130496A1 (es) |
PL (1) | PL2542080T3 (es) |
PT (1) | PT2542080T (es) |
SG (2) | SG10201501539SA (es) |
WO (1) | WO2011109536A1 (es) |
ZA (1) | ZA201207125B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5832716B2 (ja) * | 2005-10-19 | 2015-12-16 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドナトリウムの結晶,及びその製造方法 |
KR20160013273A (ko) | 2006-06-12 | 2016-02-03 | 테바 파마슈티컬 인더스트리즈 리미티드 | 안정한 라퀴니모드 제제 |
PT2682120T (pt) | 2007-12-20 | 2016-11-07 | Teva Pharma | Preparações de laquinimod estáveis |
KR20110048571A (ko) * | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 2―옥소―1,2―다이하이드로―퀴놀린 조절제 |
EP3028572A1 (en) * | 2009-06-19 | 2016-06-08 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with laquinimod |
EA025468B1 (ru) * | 2009-07-30 | 2016-12-30 | Тева Фармасьютикал Индастриз Лтд. | Лечение болезни крона с применением лаквинимода |
PL3064206T3 (pl) | 2009-08-10 | 2020-02-28 | Active Biotech Ab | Leczenie choroby Huntingtona z zastosowaniem lakwinimodu |
CA2791709A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate |
CA2791691A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of lupus nephritis using laquinimod |
JP2013521305A (ja) * | 2010-03-03 | 2013-06-10 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドを用いるループス関節炎の治療 |
SG186948A1 (en) | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
WO2013055907A1 (en) | 2011-10-12 | 2013-04-18 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
AR089862A1 (es) | 2012-02-03 | 2014-09-24 | Teva Pharma | USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA |
WO2013123419A1 (en) | 2012-02-16 | 2013-08-22 | Teva Pharmaceutical Industries Ltd. | N-ethyl-n-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinoline carboxamide, preparation and uses thereof |
TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
AU2013341506A1 (en) | 2012-11-07 | 2015-06-04 | Teva Pharmaceutical Industries Ltd. | Amine salts of Laquinimod |
CA2901849A1 (en) | 2013-03-14 | 2014-09-25 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
JP2016513665A (ja) | 2013-03-14 | 2016-05-16 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドの経皮製剤 |
SG11201608674UA (en) | 2014-04-29 | 2016-11-29 | Teva Pharma | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
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FR2340735A1 (fr) * | 1976-02-11 | 1977-09-09 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
US5540934A (en) * | 1994-06-22 | 1996-07-30 | Touitou; Elka | Compositions for applying active substances to or through the skin |
US5912349A (en) * | 1997-01-31 | 1999-06-15 | Pharmacia & Upjohn Company | Process for the preparation of roquinimex |
US6696407B1 (en) * | 1997-03-21 | 2004-02-24 | The Regents Of The University Of California | Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF |
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US6133285A (en) * | 1998-07-15 | 2000-10-17 | Active Biotech Ab | Quinoline derivatives |
PL199781B1 (pl) * | 1999-10-25 | 2008-10-31 | Active Biotech Ab | Nowe związki pochodne chinoliny, zastosowanie związków pochodnych chinoliny, zawierające je kompozycje farmaceutyczne i sposób ich wytwarzania |
US6852323B2 (en) * | 2000-07-21 | 2005-02-08 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
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AU2004251750A1 (en) * | 2003-06-25 | 2005-01-06 | Elan Pharmaceuticals, Inc. | Methods and compositions for treating rheumatoid arthritis |
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CA2579038A1 (en) * | 2004-09-02 | 2006-03-16 | Teva Pharmaceutical Industries, Ltd. | Combination therapy with glatiramer acetate and n-acetylcysteine for the treatment of multiple sclerosis |
JP5905184B2 (ja) * | 2005-10-13 | 2016-04-20 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッドHuman Genome Sciences, Inc. | 自己抗体陽性疾患を有する患者の処置に使用するための方法および組成物 |
JP5832716B2 (ja) * | 2005-10-19 | 2015-12-16 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドナトリウムの結晶,及びその製造方法 |
ZA200803327B (en) * | 2005-10-26 | 2009-09-30 | Serono Lab | Sulfonamide derivatives and use thereof for the modulation of metalloproteinases |
US20080108641A1 (en) * | 2006-02-08 | 2008-05-08 | Ajami Alfred M | Compounds for treating inflammatory disorders, demyelinating disdorders and cancers |
US8367629B2 (en) * | 2006-02-14 | 2013-02-05 | Noxxon Pharma Ag | MCP-1 binding nucleic acids and use thereof |
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KR20160013273A (ko) * | 2006-06-12 | 2016-02-03 | 테바 파마슈티컬 인더스트리즈 리미티드 | 안정한 라퀴니모드 제제 |
US20080118553A1 (en) * | 2006-06-12 | 2008-05-22 | Anton Frenkel | Tannate salt form of polypeptide mixtures, their preparation and use |
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PT2682120T (pt) * | 2007-12-20 | 2016-11-07 | Teva Pharma | Preparações de laquinimod estáveis |
KR20110048571A (ko) * | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 2―옥소―1,2―다이하이드로―퀴놀린 조절제 |
EP3028572A1 (en) * | 2009-06-19 | 2016-06-08 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with laquinimod |
EA025468B1 (ru) * | 2009-07-30 | 2016-12-30 | Тева Фармасьютикал Индастриз Лтд. | Лечение болезни крона с применением лаквинимода |
PL3064206T3 (pl) * | 2009-08-10 | 2020-02-28 | Active Biotech Ab | Leczenie choroby Huntingtona z zastosowaniem lakwinimodu |
JP2013521305A (ja) * | 2010-03-03 | 2013-06-10 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドを用いるループス関節炎の治療 |
SG186948A1 (en) * | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
CA2901849A1 (en) * | 2013-03-14 | 2014-09-25 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
-
2011
- 2011-03-02 JP JP2012556214A patent/JP2013521305A/ja not_active Withdrawn
- 2011-03-02 PT PT117513051T patent/PT2542080T/pt unknown
- 2011-03-02 MX MX2012010071A patent/MX342001B/es active IP Right Grant
- 2011-03-02 SG SG10201501539SA patent/SG10201501539SA/en unknown
- 2011-03-02 US US13/039,194 patent/US20110217295A1/en not_active Abandoned
- 2011-03-02 PL PL11751305T patent/PL2542080T3/pl unknown
- 2011-03-02 EA EA201290859A patent/EA201290859A1/ru unknown
- 2011-03-02 BR BR112012022064A patent/BR112012022064A2/pt not_active IP Right Cessation
- 2011-03-02 WO PCT/US2011/026891 patent/WO2011109536A1/en active Application Filing
- 2011-03-02 KR KR1020127025805A patent/KR20130036217A/ko not_active Application Discontinuation
- 2011-03-02 ES ES11751305.1T patent/ES2601819T3/es active Active
- 2011-03-02 SG SG2012063517A patent/SG183515A1/en unknown
- 2011-03-02 CN CN201180012107.2A patent/CN102781239B/zh not_active Expired - Fee Related
- 2011-03-02 AU AU2011223702A patent/AU2011223702B2/en not_active Ceased
- 2011-03-02 NZ NZ602512A patent/NZ602512A/en not_active IP Right Cessation
- 2011-03-02 EP EP11751305.1A patent/EP2542080B1/en not_active Not-in-force
- 2011-03-02 CA CA2791711A patent/CA2791711A1/en not_active Abandoned
- 2011-03-02 PE PE2012001382A patent/PE20130496A1/es not_active Application Discontinuation
-
2012
- 2012-08-31 CL CL2012002422A patent/CL2012002422A1/es unknown
- 2012-09-18 CO CO12160941A patent/CO6630086A2/es unknown
- 2012-09-21 ZA ZA2012/07125A patent/ZA201207125B/en unknown
-
2013
- 2013-03-05 US US13/785,511 patent/US20130184310A1/en not_active Abandoned
- 2013-05-14 HK HK13105722.9A patent/HK1177876A1/zh not_active IP Right Cessation
-
2014
- 2014-12-01 US US14/556,321 patent/US20150086549A1/en not_active Abandoned
-
2016
- 2016-04-04 US US15/089,792 patent/US20160213663A1/en not_active Abandoned
- 2016-05-25 JP JP2016104447A patent/JP2016196473A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
SG10201501539SA (en) | 2015-04-29 |
MX2012010071A (es) | 2012-10-03 |
WO2011109536A1 (en) | 2011-09-09 |
US20110217295A1 (en) | 2011-09-08 |
US20160213663A1 (en) | 2016-07-28 |
ZA201207125B (en) | 2014-06-25 |
MX342001B (es) | 2016-09-09 |
CN102781239A (zh) | 2012-11-14 |
SG183515A1 (en) | 2012-10-30 |
PT2542080T (pt) | 2016-11-16 |
EP2542080A4 (en) | 2013-07-17 |
JP2016196473A (ja) | 2016-11-24 |
JP2013521305A (ja) | 2013-06-10 |
ES2601819T3 (es) | 2017-02-16 |
CL2012002422A1 (es) | 2012-12-21 |
AU2011223702A1 (en) | 2012-10-25 |
US20150086549A1 (en) | 2015-03-26 |
CO6630086A2 (es) | 2013-03-01 |
US20130184310A1 (en) | 2013-07-18 |
CN102781239B (zh) | 2015-01-21 |
BR112012022064A2 (pt) | 2015-09-08 |
KR20130036217A (ko) | 2013-04-11 |
EP2542080A1 (en) | 2013-01-09 |
HK1177876A1 (zh) | 2013-08-30 |
NZ602512A (en) | 2014-07-25 |
CA2791711A1 (en) | 2011-09-09 |
AU2011223702B2 (en) | 2016-07-14 |
PL2542080T3 (pl) | 2017-02-28 |
EP2542080B1 (en) | 2016-08-31 |
EA201290859A1 (ru) | 2013-04-30 |
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