PE20120791A1 - Composiciones y metodos para terapia prolongada con aminopiridinas - Google Patents

Composiciones y metodos para terapia prolongada con aminopiridinas

Info

Publication number
PE20120791A1
PE20120791A1 PE2011001475A PE2011001475A PE20120791A1 PE 20120791 A1 PE20120791 A1 PE 20120791A1 PE 2011001475 A PE2011001475 A PE 2011001475A PE 2011001475 A PE2011001475 A PE 2011001475A PE 20120791 A1 PE20120791 A1 PE 20120791A1
Authority
PE
Peru
Prior art keywords
aminopyridines
compositions
methods
prolonged therapy
referred
Prior art date
Application number
PE2011001475A
Other languages
English (en)
Inventor
Andrew R Blight
Ron Cohen
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42562065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20120791(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of PE20120791A1 publication Critical patent/PE20120791A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

REFERIDA A UNA COMPOSICION DE LIBERACION SOSTENIDA DE 10 mg DE 4-AMINOPIRIDINA PARA MANTENER UNA MEJORA EN LA VELOCIDAD AL CAMINAR DE UN PACIENTE DE ESCLEROSIS MULTIPLE POR UN PERIODO DE TIEMPO PROLONGADO DE AL MENOS 1 ANO. REFERIDA ADEMAS AL USO DE DICHA COMPOSICION ASI COMO EL METODO QUE COMPRENDE LA ADMINISTRACION 2 VECES AL DIA EN UNA DOSIS DE 10 mg
PE2011001475A 2009-02-11 2010-02-11 Composiciones y metodos para terapia prolongada con aminopiridinas PE20120791A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15167909P 2009-02-11 2009-02-11
US25956309P 2009-11-09 2009-11-09
US28587209P 2009-12-11 2009-12-11
US28895309P 2009-12-22 2009-12-22
US29925910P 2010-01-28 2010-01-28

Publications (1)

Publication Number Publication Date
PE20120791A1 true PE20120791A1 (es) 2012-07-08

Family

ID=42562065

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2011001475A PE20120791A1 (es) 2009-02-11 2010-02-11 Composiciones y metodos para terapia prolongada con aminopiridinas

Country Status (22)

Country Link
US (3) US20120029035A1 (es)
JP (1) JP2012517449A (es)
KR (3) KR20180114250A (es)
CN (2) CN102046174A (es)
AR (1) AR075413A1 (es)
AU (2) AU2010213663A1 (es)
BR (2) BRPI1000030A2 (es)
CA (1) CA2751581A1 (es)
CL (1) CL2011001927A1 (es)
CO (1) CO6440534A2 (es)
EA (1) EA022755B1 (es)
EC (1) ECSP11011311A (es)
IL (1) IL214500A0 (es)
MX (1) MX2011008485A (es)
NI (1) NI201100155A (es)
NZ (1) NZ595046A (es)
PE (1) PE20120791A1 (es)
SG (2) SG10201609184PA (es)
TN (1) TN2011000403A1 (es)
TW (2) TW201034665A (es)
UY (2) UY32445A (es)
WO (2) WO2010093838A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
US20150111930A1 (en) * 2013-10-23 2015-04-23 Afgin Pharma, Llc Topical regional neuro-affective therapy
AR078323A1 (es) * 2009-09-04 2011-11-02 Acorda Therapeutics Inc Tratamiento con fampridina de liberacion sostenida en pacientes con esclerosis multiple
CN102442942A (zh) * 2010-10-08 2012-05-09 天津和美生物技术有限公司 4-氨基吡啶的多晶型物及其制备和应用
EP2667869A1 (en) * 2011-01-28 2013-12-04 Acorda Therapeutics, Inc. Use of potassium channel blockers to treat cerebral palsy
MX2014009811A (es) * 2012-02-13 2014-09-08 Acorda Therapeutics Inc Metodos para tratar deficiencia en la marcha y/o equilibrio en pacientes con esclerosis multiple que utilizan una aminopiridina.
WO2014028387A1 (en) * 2012-08-13 2014-02-20 Acorda Therapeutics, Inc. Methods for improving walking capacity in patients with multiple sclerosis using an aminopyridine
US11145417B2 (en) * 2014-02-04 2021-10-12 Optimata Ltd. Method and system for prediction of medical treatment effect
RU2580837C1 (ru) * 2015-05-05 2016-04-10 Федеральное Государственное Автономное Образовательное Учреждение Высшего Профессионального Образования "Московский Физико-Технический Институт (Государственный Университет)" Кристаллогидрат 4-аминопиридина, способ его получения, фармацевтическая композиция и способ лечения и/или профилактики на её основе
US10172842B2 (en) 2015-09-11 2019-01-08 PharmaDax Inc. Sustained release oral dosage form containing dalfampridine
WO2022124946A1 (ru) * 2020-12-10 2022-06-16 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые полиморфные формы 4-аминопиридина и их фармацевтическое применение
CN112914884B (zh) * 2021-01-19 2022-02-11 重庆火后草科技有限公司 通过稳态时长置信度测量睡眠状态下的体重值的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
US6288026B1 (en) * 1999-02-24 2001-09-11 Heinrich Exner Process and composition for treating diseases with an oil-in-water emulsion
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions

Also Published As

Publication number Publication date
UY32444A (es) 2010-09-30
AU2016219650A1 (en) 2016-09-15
JP2012517449A (ja) 2012-08-02
TN2011000403A1 (en) 2013-03-27
AU2016219650B2 (en) 2018-05-10
CN101896182A (zh) 2010-11-24
ECSP11011311A (es) 2011-10-31
UY32445A (es) 2010-09-30
AU2010213663A1 (en) 2011-09-29
WO2010093838A1 (en) 2010-08-19
SG173641A1 (en) 2011-09-29
CN102046174A (zh) 2011-05-04
EA022755B1 (ru) 2016-02-29
CA2751581A1 (en) 2010-08-19
CL2011001927A1 (es) 2012-07-20
BRPI1000030A2 (pt) 2018-02-14
AU2016219650C1 (en) 2018-08-23
BRPI1000031A2 (pt) 2018-02-14
NI201100155A (es) 2012-02-16
AR075413A1 (es) 2011-03-30
US20120029035A1 (en) 2012-02-02
EA201171043A1 (ru) 2012-02-28
US20170319562A1 (en) 2017-11-09
SG10201609184PA (en) 2016-12-29
NZ595046A (en) 2013-10-25
CO6440534A2 (es) 2012-05-15
IL214500A0 (en) 2011-09-27
TW201034665A (en) 2010-10-01
MX2011008485A (es) 2011-11-04
KR20120000560A (ko) 2012-01-02
US20150313886A1 (en) 2015-11-05
TW201032809A (en) 2010-09-16
KR20170034452A (ko) 2017-03-28
KR20180114250A (ko) 2018-10-17
WO2010093839A1 (en) 2010-08-19

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