PE20120817A1 - Peptidos tau antigenicos y usos de los mismos - Google Patents
Peptidos tau antigenicos y usos de los mismosInfo
- Publication number
- PE20120817A1 PE20120817A1 PE2012000116A PE2012000116A PE20120817A1 PE 20120817 A1 PE20120817 A1 PE 20120817A1 PE 2012000116 A PE2012000116 A PE 2012000116A PE 2012000116 A PE2012000116 A PE 2012000116A PE 20120817 A1 PE20120817 A1 PE 20120817A1
- Authority
- PE
- Peru
- Prior art keywords
- sequence
- seq
- amino acids
- vlp
- immunogen
- Prior art date
Links
- 230000000890 antigenic effect Effects 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 5
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 101000854943 Enterobacteria phage T4 Valyl-tRNA ligase modifier Proteins 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22986009P | 2009-07-30 | 2009-07-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20120817A1 true PE20120817A1 (es) | 2012-07-07 |
Family
ID=42941871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2012000116A PE20120817A1 (es) | 2009-07-30 | 2010-07-20 | Peptidos tau antigenicos y usos de los mismos |
Country Status (17)
Country | Link |
---|---|
US (1) | US20110177109A1 (en:Method) |
EP (1) | EP2459214A1 (en:Method) |
JP (1) | JP2013500326A (en:Method) |
KR (2) | KR20120049900A (en:Method) |
CN (1) | CN102596236B (en:Method) |
AR (1) | AR078085A1 (en:Method) |
AU (1) | AU2010277254B2 (en:Method) |
CA (1) | CA2768346A1 (en:Method) |
CO (1) | CO6612199A2 (en:Method) |
IN (1) | IN2012DN00446A (en:Method) |
MX (1) | MX2012001194A (en:Method) |
NZ (2) | NZ598356A (en:Method) |
PE (1) | PE20120817A1 (en:Method) |
RU (2) | RU2518291C2 (en:Method) |
SG (1) | SG177637A1 (en:Method) |
TW (2) | TW201436804A (en:Method) |
WO (1) | WO2011013034A1 (en:Method) |
Families Citing this family (45)
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SI2759306T1 (sl) | 2008-12-09 | 2016-05-31 | Coley Pharmaceutical Group, Inc. | Imunostimulacijski oligonukleotidi |
UA107571C2 (xx) | 2009-04-03 | 2015-01-26 | Фармацевтична композиція | |
JP5917394B2 (ja) | 2009-06-10 | 2016-05-11 | ニューヨーク・ユニバーシティ | 病理学的タウタンパク質の免疫学的標的化方法 |
CN103502272B (zh) * | 2010-10-07 | 2016-06-15 | Ac免疫有限公司 | 识别Tau的磷酸化特异抗体 |
AU2013205313B2 (en) * | 2010-10-07 | 2016-05-19 | Ac Immune S.A. | Phosphospecific antibodies recognising tau |
WO2012106363A2 (en) | 2011-01-31 | 2012-08-09 | Intellect Neurosciences Inc. | Treatment of tauopathies |
MX339762B (es) | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
MX354662B (es) | 2011-10-07 | 2018-03-14 | Ac Immune Sa | Anticuerpos fosfoespecificos que reconocen la tau. |
KR102132041B1 (ko) | 2012-04-05 | 2020-07-09 | 에이씨 이뮨 에스.에이. | 인간화된 타우 항체 |
SG11201408626YA (en) * | 2012-07-03 | 2015-03-30 | Univ Washington | Antibodies to tau |
US9567395B2 (en) | 2012-08-16 | 2017-02-14 | Ipierian, Inc. | Methods of treating a tauopathy |
US8980270B2 (en) | 2013-01-18 | 2015-03-17 | Ipierian, Inc. | Methods of treating a tauopathy |
RU2661111C2 (ru) | 2013-03-15 | 2018-07-11 | Ац Иммуне С.А. | Антитела к тау и способы применения |
EP3027205A4 (en) * | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
CN105939722A (zh) | 2014-02-14 | 2016-09-14 | 伊皮埃里安股份有限公司 | Tau肽,抗Tau抗体,及其使用方法 |
TWI664190B (zh) | 2014-06-27 | 2019-07-01 | 美商C2N醫療診斷有限責任公司 | 人類化抗-tau抗體 |
JP6913018B2 (ja) | 2014-07-08 | 2021-08-04 | ニューヨーク・ユニバーシティ | タウイメージングリガンド、ならびにタウ異常症の診断および治療におけるそれらの使用 |
WO2016154522A1 (en) * | 2015-03-25 | 2016-09-29 | Stc. Unm | Immunotherapy compositions and methods for treatment of tauopathy and transgenic mouse |
TN2017000543A1 (en) | 2015-07-06 | 2019-04-12 | Ucb Biopharma Sprl | Tau-binding antibodies |
CN108135986B (zh) | 2015-08-13 | 2022-07-29 | 纽约大学 | 对于Tau的截短的Asp421表位特异性的基于抗体的分子和它们在诊断和治疗Tau疾病中的用途 |
US11884707B2 (en) | 2016-09-29 | 2024-01-30 | Regeneron Pharmaceuticals, Inc. | Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase 1 (IDO1) and methods of making and using same |
GB201700487D0 (en) | 2017-01-11 | 2017-02-22 | Hermon-Taylor John | Diagnostic |
CA3079423A1 (en) * | 2017-10-25 | 2019-05-02 | Janssen Pharmaceuticals, Inc. | Compositions of phosphorylated tau peptides and uses thereof |
KR20250057135A (ko) * | 2017-10-27 | 2025-04-28 | 유나이티드 뉴로사이언스 | 타우 펩타이드 면역원 작제물 |
CN109870581B (zh) * | 2017-12-04 | 2021-05-04 | 厦门万泰凯瑞生物技术有限公司 | 一种定量检测HBsAg的试剂盒及方法 |
CN108314737B (zh) * | 2018-01-25 | 2021-03-16 | 中国科学院过程工程研究所 | 一种重组蛋白及其制备方法和应用 |
CN110548135B (zh) * | 2018-05-31 | 2023-06-06 | 长春百克生物科技股份公司 | 磷酸化多肽抗原疫苗及其制备方法和应用 |
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JP7719713B2 (ja) | 2018-10-07 | 2025-08-06 | ザ ユニヴァーシティ オブ ブリティッシュ コロンビア | α-シヌクレインの立体配座特異的エピトープ、それに対する抗体、およびそれに関連する方法 |
US20220275067A1 (en) * | 2019-02-08 | 2022-09-01 | Prothena Biosciences Limited | Antibodies recognizing tau |
EP3920966A2 (en) | 2019-02-08 | 2021-12-15 | AC Immune S.A. | Method of safe administration of phosphorylated tau peptide vaccine |
US20200291391A1 (en) * | 2019-03-12 | 2020-09-17 | Indi Molecular, Inc. | Cross-linked epitopes and methods of use thereof |
EP3946605A1 (en) | 2019-04-05 | 2022-02-09 | Tauc3 Biologics Limited | Anti-tauc3 antibodies and uses thereof |
US12201679B2 (en) | 2019-04-05 | 2025-01-21 | Institute For Systems Biology | Epitope-targeted peptide immunostimulants |
TW202110478A (zh) | 2019-04-24 | 2021-03-16 | 美商健生醫藥公司 | Tau疫苗之異種投予 |
WO2020236969A1 (en) | 2019-05-20 | 2020-11-26 | Indi Molecular, Inc. | Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1) |
AU2020284288A1 (en) * | 2019-05-27 | 2022-01-20 | Promis Neurosciences Inc. | Conformation-specific epitopes in tau, antibodies thereto and methods related thereof |
GB2585252A (en) * | 2019-07-05 | 2021-01-06 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
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JP2023536746A (ja) * | 2020-08-07 | 2023-08-29 | プロシーナ バイオサイエンシーズ リミテッド | アルツハイマー病の処置のためのタウワクチン |
WO2022054795A1 (ja) * | 2020-09-08 | 2022-03-17 | 国立大学法人大阪大学 | リン酸化タウタンパク質を標的とする免疫原性組成物 |
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-
2010
- 2010-07-20 CA CA2768346A patent/CA2768346A1/en not_active Abandoned
- 2010-07-20 AU AU2010277254A patent/AU2010277254B2/en not_active Ceased
- 2010-07-20 JP JP2012522292A patent/JP2013500326A/ja active Pending
- 2010-07-20 WO PCT/IB2010/053313 patent/WO2011013034A1/en active Application Filing
- 2010-07-20 MX MX2012001194A patent/MX2012001194A/es not_active Application Discontinuation
- 2010-07-20 CN CN201080040148.8A patent/CN102596236B/zh not_active Expired - Fee Related
- 2010-07-20 IN IN446DEN2012 patent/IN2012DN00446A/en unknown
- 2010-07-20 NZ NZ598356A patent/NZ598356A/en not_active IP Right Cessation
- 2010-07-20 NZ NZ618391A patent/NZ618391A/en not_active IP Right Cessation
- 2010-07-20 SG SG2012002390A patent/SG177637A1/en unknown
- 2010-07-20 PE PE2012000116A patent/PE20120817A1/es not_active Application Discontinuation
- 2010-07-20 EP EP10739402A patent/EP2459214A1/en not_active Withdrawn
- 2010-07-20 RU RU2012102701/10A patent/RU2518291C2/ru not_active IP Right Cessation
- 2010-07-20 KR KR1020127005415A patent/KR20120049900A/ko not_active Abandoned
- 2010-07-20 KR KR1020137028550A patent/KR20130127547A/ko not_active Ceased
- 2010-07-29 AR ARP100102753A patent/AR078085A1/es unknown
- 2010-07-29 US US12/846,719 patent/US20110177109A1/en not_active Abandoned
- 2010-07-29 TW TW103104138A patent/TW201436804A/zh unknown
- 2010-07-29 TW TW099125165A patent/TWI461209B/zh not_active IP Right Cessation
-
2012
- 2012-02-15 CO CO12026764A patent/CO6612199A2/es unknown
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2014
- 2014-03-31 RU RU2014112002/10A patent/RU2014112002A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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CO6612199A2 (es) | 2013-02-01 |
WO2011013034A4 (en) | 2011-04-28 |
NZ618391A (en) | 2015-07-31 |
KR20120049900A (ko) | 2012-05-17 |
MX2012001194A (es) | 2012-03-07 |
WO2011013034A1 (en) | 2011-02-03 |
RU2014112002A (ru) | 2015-10-10 |
IN2012DN00446A (en:Method) | 2015-05-15 |
AR078085A1 (es) | 2011-10-12 |
CA2768346A1 (en) | 2011-02-03 |
NZ598356A (en) | 2014-06-27 |
AU2010277254B2 (en) | 2015-05-07 |
CN102596236A (zh) | 2012-07-18 |
TWI461209B (zh) | 2014-11-21 |
EP2459214A1 (en) | 2012-06-06 |
JP2013500326A (ja) | 2013-01-07 |
TW201436804A (zh) | 2014-10-01 |
RU2012102701A (ru) | 2013-09-10 |
KR20130127547A (ko) | 2013-11-22 |
US20110177109A1 (en) | 2011-07-21 |
TW201106968A (en) | 2011-03-01 |
CN102596236B (zh) | 2015-06-24 |
SG177637A1 (en) | 2012-03-29 |
RU2518291C2 (ru) | 2014-06-10 |
AU2010277254A1 (en) | 2012-02-09 |
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