PE20060351A1 - Oxazolidinonas que contienen oxindoles como agentes antibacterianos - Google Patents

Oxazolidinonas que contienen oxindoles como agentes antibacterianos

Info

Publication number
PE20060351A1
PE20060351A1 PE2005000905A PE2005000905A PE20060351A1 PE 20060351 A1 PE20060351 A1 PE 20060351A1 PE 2005000905 A PE2005000905 A PE 2005000905A PE 2005000905 A PE2005000905 A PE 2005000905A PE 20060351 A1 PE20060351 A1 PE 20060351A1
Authority
PE
Peru
Prior art keywords
oxo
antibacterial agents
oxazolidine
indol
dihydro
Prior art date
Application number
PE2005000905A
Other languages
English (en)
Inventor
Gary Wayne Luehr
Rama Jain
Vara Prasad Venkata Nagendra Josyula
Mikhail Fedorovich Gordeev
Adam Robert Renslo
Original Assignee
Pharmacia And Upjohn Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079333&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20060351(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia And Upjohn Company Llc filed Critical Pharmacia And Upjohn Company Llc
Publication of PE20060351A1 publication Critical patent/PE20060351A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

REFERIDA A UN COMPUESTO DERIVADO DE OXAZOLIDINONA DE FORMULA I, DONDE Y1 ES -CH- O -CF-; R1 ES ALQUILO C1-C4, SUSTITUIDO OPCIONALMENTE CON UN ATOMO DE FLUORO O R1 ES CICLOALQUILO C3-C5; R2 ES H O CH3. SON COMPUESTOS PREFERIDOS: (5R)-3-(1-ISOPROPIL-2-OXO-2,3-DIHIDRO-1H-INDOL-5-IL)-2-OXO-OXAZOLIDINA-5-CARBOXILICO, AMIDA DEL ACIDO (5R)-3-(1-METIL-2-OXO-2,3-DIHIDRO-1H-INDOL-5-IL)-2-OXO-OXAZOLIDINA-5-CARBOXILICO, AMIDA DEL ACIDO (5R)-3-(7-FLUORO-1-METIL-2-OXO-2,3-DIHIDRO-1H-INDOL-5-IL)-2-OXO-OXAZOLIDINA-5-CARBOXILICO, ENTRE OTROS. TAMBIEN ESTA REFERIDA A UNA COMPOSICION Y A UN PROCEDIMIENTO DE PREPARACION. DICHOS COMPUESTOS SON UTILES COMO AGENTES ANTIBACTERIANOS EN EL TRATAMIENTO DE INFECCIONES MICROBIANAS GRAM-POSITIVAS O GRAM-NEGATIVAS
PE2005000905A 2004-08-06 2005-08-03 Oxazolidinonas que contienen oxindoles como agentes antibacterianos PE20060351A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59982204P 2004-08-06 2004-08-06

Publications (1)

Publication Number Publication Date
PE20060351A1 true PE20060351A1 (es) 2006-05-03

Family

ID=35079333

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005000905A PE20060351A1 (es) 2004-08-06 2005-08-03 Oxazolidinonas que contienen oxindoles como agentes antibacterianos

Country Status (24)

Country Link
US (2) US20080262056A1 (es)
EP (2) EP1781642A1 (es)
JP (2) JP2008509126A (es)
CN (1) CN101001853A (es)
AP (1) AP2007003904A0 (es)
AR (1) AR050101A1 (es)
AU (1) AU2005270951A1 (es)
BR (2) BRPI0514020A (es)
CA (2) CA2576041A1 (es)
EA (1) EA200700322A1 (es)
GT (1) GT200500204A (es)
IL (1) IL180957A0 (es)
MA (1) MA28793B1 (es)
MX (2) MX2007001568A (es)
NL (1) NL1029686C2 (es)
NO (1) NO20071230L (es)
PA (1) PA8640901A1 (es)
PE (1) PE20060351A1 (es)
SV (1) SV2006002180A (es)
TN (1) TNSN07043A1 (es)
TW (1) TWI289448B (es)
UY (1) UY29048A1 (es)
WO (2) WO2006016220A1 (es)
ZA (1) ZA200700476B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006231919A1 (en) 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents
KR20070116989A (ko) * 2005-04-06 2007-12-11 파마시아 앤드 업존 캄파니 엘엘씨 항균제로서의 옥신돌 옥사졸리디논
CN103420995B (zh) * 2013-09-07 2015-07-01 吉首大学 噁唑烷酮-烷胺基-呋喃酮型化合物及其制法和用途
CN103483329B (zh) * 2013-09-07 2015-08-05 吉首大学 呋喃酮-芳基-噁唑烷酮型化合物及其制法和用途
CN107698567B (zh) * 2017-10-25 2020-09-15 西南大学 靛红唑醇类化合物及其制备方法和医药应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68929303T2 (de) * 1988-09-15 2002-05-02 Pharmacia & Upjohn Co., Kalamazoo 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
US5164510A (en) * 1988-09-15 1992-11-17 The Upjohn Company 5'Indolinyl-5β-amidomethyloxazolidin-2-ones
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
ES2193201T3 (es) * 1994-11-15 2003-11-01 Upjohn Co Agentes antibacterianos tipo oxazolidonas sustituidas con oxazina y tiazina biciclica.
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
RU2175324C2 (ru) * 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
DE19601627A1 (de) * 1996-01-18 1997-07-24 Bayer Ag Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
DE69716925T2 (de) * 1996-08-21 2003-09-11 Pharmacia & Upjohn Co., Kalamazoo Isoxazoline derivate und ihre verwendung als antimikroben
GB9717804D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
EP1049682A1 (en) * 1998-01-23 2000-11-08 Versicor, Inc. Oxazolidinone combinatorial libraries, compositions and methods of preparation
GB9812019D0 (en) * 1998-06-05 1998-07-29 Zeneca Ltd Chemical compounds
IL144669A0 (en) * 1999-02-01 2002-05-23 Upjohn Co Process to prepare cyclic-sulfur fluorine containing oxazolidinones
JP2003501351A (ja) * 1999-05-27 2003-01-14 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤としての二環系オキサゾリジノン
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7012088B2 (en) * 2003-02-24 2006-03-14 Pharmacia & Upjohn Company Indolone oxazolidinones and derivatives thereof
AU2006231919A1 (en) * 2005-04-06 2006-10-12 Pharmacia & Upjohn Company Llc 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents

Also Published As

Publication number Publication date
US20060030609A1 (en) 2006-02-09
CA2576041A1 (en) 2006-02-16
JP2008509126A (ja) 2008-03-27
TWI289448B (en) 2007-11-11
WO2006016220A1 (en) 2006-02-16
PA8640901A1 (es) 2007-01-17
BRPI0514020A (pt) 2008-05-27
TW200612924A (en) 2006-05-01
MX2007001526A (es) 2007-03-27
AU2005270951A1 (en) 2006-02-16
EA200700322A1 (ru) 2007-08-31
IL180957A0 (en) 2007-07-04
CN101001853A (zh) 2007-07-18
EP1781642A1 (en) 2007-05-09
AP2007003904A0 (en) 2007-02-28
GT200500204A (es) 2006-03-02
TNSN07043A1 (fr) 2008-06-02
NL1029686C2 (nl) 2006-07-18
AR050101A1 (es) 2006-09-27
EP1781643A1 (en) 2007-05-09
BRPI0513083A (pt) 2008-04-22
UY29048A1 (es) 2006-03-31
MX2007001568A (es) 2007-04-16
CA2575702A1 (en) 2006-02-16
SV2006002180A (es) 2006-06-26
WO2006016221A1 (en) 2006-02-16
MA28793B1 (fr) 2007-08-01
ZA200700476B (en) 2008-10-29
NL1029686A1 (nl) 2006-02-07
US20080262056A1 (en) 2008-10-23
NO20071230L (no) 2007-05-04
JP2008509125A (ja) 2008-03-27

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