PE20050728A1 - Forma de dosificacion a prueba de abuso - Google Patents

Forma de dosificacion a prueba de abuso

Info

Publication number
PE20050728A1
PE20050728A1 PE2004000756A PE2004000756A PE20050728A1 PE 20050728 A1 PE20050728 A1 PE 20050728A1 PE 2004000756 A PE2004000756 A PE 2004000756A PE 2004000756 A PE2004000756 A PE 2004000756A PE 20050728 A1 PE20050728 A1 PE 20050728A1
Authority
PE
Peru
Prior art keywords
agent
avocosizing
principal
polyethylene
optionally
Prior art date
Application number
PE2004000756A
Other languages
English (en)
Inventor
Johannes Bartholomaus
Heinrich Kugelmann
Elisabeth Arkenau-Maric
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34199050&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20050728(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10336400A external-priority patent/DE10336400A1/de
Priority claimed from DE10361596A external-priority patent/DE10361596A1/de
Priority claimed from DE102004020220A external-priority patent/DE102004020220A1/de
Priority claimed from DE102004032051A external-priority patent/DE102004032051A1/de
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of PE20050728A1 publication Critical patent/PE20050728A1/es

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Classifications

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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

SE REFIERE A UNA FORMA DE DOSIFICACION TERMOFORADA MEDIANTE EXTRUSION SIN DECOLORACION A PRUEBA DE ABUSO, CARACTERIZADA POR COMPRENDER: A) UNO O MAS PRINCIPIOS ACTIVOS SUSCEPTIBLES DE ABUSO SELECCIONADOS DEL GRUPO DE OPIODES, TRANQUILIZANTES, ESTIMULANTES BARBITURICOS Y OTROS NARCOTICOS; B) OPCIONALMENTE SUSTANCIAS AUXILIARES FISIOLOGICAMENTE ACEPTABLES COMO PLASTIFICANTES O ANTIOXIDANTES U OTRAS SUSTANCIAS AUXILIARES COMO AL MENOS: UNA SUSTANCIA QUE IRRITA LAS FOSAS NASALES Y/O FARINGE, UN AGENTE VISCOSIZANTE, UN ANTAGONISTA DEL PRINCIPIO ACTIVO SUSCEPTIBLE A ABUSO, UN COLORANTE COMO AGENTE AVERSIVO O UNA SUSTANCIA AMARGA; C) AL MENOS UN POLIMERO SINTETICO O NATURAL SELECCIONADO DEL GRUPO DE OXIDOS DE POLIETILENO, DE POLIMETILENO O DE POLIPROPILENO, POLIETILENO, POLIPROPILENO, ENTRE OTROS Y D) OPCIONALMENTE AL MENOS UNA CERA NATURAL, SEMISINTETICA O SINTETICA CON UN PUNTO DE ABLANDAMIENTO DE AL MENOS 60°C COMO LA CERA DE CARNAUBA O CERA DE ABEJAS. ADEMAS LOS COMPONENTES C) Y OPCIONALMENTE D) TIENEN CADA UNO UNA DUREZA DE AL MENOS 500 N. ESTA FORMA DE DOSIFICACION PUEDE TENER LA FORMA DE MULTIPLES PARTICULAS COMO MICROCOMPRIMIDOS, MICROPELLETS, GRANULOS ESFEROIDALES, PELOTILLAS O PELLETS, OPCIONALMENTE LLENADOS EN CAPSULAS O COMPRIMIDOS EN COMPRIMIDOS. TAMBIEN SE REFIERE A UN PROCESO DE PREPARACION DE ESTA FORMA DE DOSIFICACION
PE2004000756A 2003-08-06 2004-08-05 Forma de dosificacion a prueba de abuso PE20050728A1 (es)

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DE10336400A DE10336400A1 (de) 2003-08-06 2003-08-06 Gegen Missbrauch gesicherte Darreichungsform
DE10361596A DE10361596A1 (de) 2003-12-24 2003-12-24 Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004020220A DE102004020220A1 (de) 2004-04-22 2004-04-22 Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE102004032051A DE102004032051A1 (de) 2004-07-01 2004-07-01 Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform

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US20140086847A1 (en) 2014-03-27
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WO2005016313A1 (de) 2005-02-24
DE502004004205D1 (de) 2007-08-09
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CA2534925A1 (en) 2005-02-24
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US20160166517A1 (en) 2016-06-16
US20070183980A1 (en) 2007-08-09
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BRPI0413361A (pt) 2006-10-10
PT1842533E (pt) 2013-05-17
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BRPI0413361B8 (pt) 2021-05-25
BR122018068298B8 (pt) 2021-07-27
EP1658054A1 (de) 2006-05-24
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