PE120799A1 - Fosfato de tetrahidrofurano antifungal - Google Patents

Fosfato de tetrahidrofurano antifungal

Info

Publication number
PE120799A1
PE120799A1 PE1998000905A PE00090598A PE120799A1 PE 120799 A1 PE120799 A1 PE 120799A1 PE 1998000905 A PE1998000905 A PE 1998000905A PE 00090598 A PE00090598 A PE 00090598A PE 120799 A1 PE120799 A1 PE 120799A1
Authority
PE
Peru
Prior art keywords
antifungal
phosphate
tetrahydrophuran
infections
po3h2
Prior art date
Application number
PE1998000905A
Other languages
English (en)
Inventor
Anil K Saksena
Ashit Ganguly
Frank Bennett
Naginbhai M Patel
Vyyoor Girijavallabhan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE120799A1 publication Critical patent/PE120799A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • C07F9/6518—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE REFIERE A UN FOSFATO DE TETRAHIDROFURANO ANTIFUNGAL DE FORMULA I, DONDE G ES H o PO3H2. EL COMPUESTO I ES UN ANTIFUNGAL DE AMPLIO ESPECTRO Y TIENE UNA SOLUBILIDAD ADECUADA PARA LA ADMINISTRACION PARENTERAL; POR LO QUE SE UTILIZA PARA TRATAR O PREVENIR LAS INFECCIONES FUNGALES SISTEMICAS ESPECIALMENTE POR ASPERGILLUS, CANDIDA, CRYPTOCOCCUS E INFECCIONES OPORTUNISTAS
PE1998000905A 1997-09-25 1998-09-22 Fosfato de tetrahidrofurano antifungal PE120799A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93782797A 1997-09-25 1997-09-25

Publications (1)

Publication Number Publication Date
PE120799A1 true PE120799A1 (es) 1999-12-01

Family

ID=25470461

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998000905A PE120799A1 (es) 1997-09-25 1998-09-22 Fosfato de tetrahidrofurano antifungal

Country Status (26)

Country Link
EP (1) EP1027349B1 (es)
JP (1) JP3473949B2 (es)
KR (1) KR20010024297A (es)
CN (1) CN1125066C (es)
AR (1) AR015458A1 (es)
AT (1) ATE286502T1 (es)
AU (1) AU1698199A (es)
BR (1) BR9812671A (es)
CA (1) CA2304624C (es)
CO (1) CO5011088A1 (es)
DE (1) DE69828524T2 (es)
ES (1) ES2232974T3 (es)
HK (1) HK1025960A1 (es)
HU (1) HUP0004616A3 (es)
ID (1) ID28294A (es)
IL (1) IL134469A0 (es)
MY (1) MY133775A (es)
NO (1) NO20001557L (es)
NZ (1) NZ502709A (es)
PE (1) PE120799A1 (es)
PL (1) PL339488A1 (es)
PT (1) PT1027349E (es)
SK (1) SK3912000A3 (es)
TR (1) TR200000753T2 (es)
WO (1) WO1999015522A1 (es)
ZA (1) ZA988688B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1915500A (en) 1998-11-20 2000-06-13 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
CN102906087B (zh) * 2010-05-19 2016-03-23 桑多斯股份公司 制备手性三唑酮的方法
CN111138421A (zh) * 2019-12-26 2020-05-12 上海英诺富成生物科技有限公司 抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693626A (en) * 1993-12-21 1997-12-02 Schering Corporation Tetrahydrofuran antifungals
ATE204875T1 (de) * 1993-12-21 2001-09-15 Schering Corp Fungizide tetrahydrofurane

Also Published As

Publication number Publication date
IL134469A0 (en) 2001-04-30
DE69828524T2 (de) 2005-12-29
EP1027349B1 (en) 2005-01-05
MY133775A (en) 2007-11-30
EP1027349A1 (en) 2000-08-16
BR9812671A (pt) 2000-08-22
HK1025960A1 (en) 2000-12-01
PT1027349E (pt) 2005-05-31
ID28294A (id) 2001-05-10
AU1698199A (en) 1999-04-12
CA2304624C (en) 2007-06-19
TR200000753T2 (tr) 2001-01-22
DE69828524D1 (de) 2005-02-10
CN1271356A (zh) 2000-10-25
ZA988688B (en) 1999-03-23
KR20010024297A (ko) 2001-03-26
WO1999015522A1 (en) 1999-04-01
ES2232974T3 (es) 2005-06-01
CN1125066C (zh) 2003-10-22
JP2001517665A (ja) 2001-10-09
NZ502709A (en) 2001-11-30
AR015458A1 (es) 2001-05-02
HUP0004616A3 (en) 2002-04-29
CA2304624A1 (en) 1999-04-01
CO5011088A1 (es) 2001-02-28
SK3912000A3 (en) 2000-08-14
ATE286502T1 (de) 2005-01-15
PL339488A1 (en) 2000-12-18
HUP0004616A2 (hu) 2002-03-28
NO20001557D0 (no) 2000-03-24
JP3473949B2 (ja) 2003-12-08
NO20001557L (no) 2000-03-24

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