IL134469A0 - Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agent - Google Patents
Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agentInfo
- Publication number
- IL134469A0 IL134469A0 IL13446998A IL13446998A IL134469A0 IL 134469 A0 IL134469 A0 IL 134469A0 IL 13446998 A IL13446998 A IL 13446998A IL 13446998 A IL13446998 A IL 13446998A IL 134469 A0 IL134469 A0 IL 134469A0
- Authority
- IL
- Israel
- Prior art keywords
- corrersponding
- prodrugs
- tetrahydrofuran
- phosphate
- antifungal agent
- Prior art date
Links
- PSMHETLGQXNXPJ-UHFFFAOYSA-N OOP(=O)(O)O.O1CCCC1 Chemical class OOP(=O)(O)O.O1CCCC1 PSMHETLGQXNXPJ-UHFFFAOYSA-N 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- 239000003429 antifungal agent Substances 0.000 title 1
- 229940002612 prodrug Drugs 0.000 title 1
- 239000000651 prodrug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
- C07F9/6518—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93782797A | 1997-09-25 | 1997-09-25 | |
| PCT/US1998/018508 WO1999015522A1 (en) | 1997-09-25 | 1998-09-22 | Tetrahydrofuran phosphate- and hydroxy esters, as prodrugs for the corresponding antifungal agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL134469A0 true IL134469A0 (en) | 2001-04-30 |
Family
ID=25470461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13446998A IL134469A0 (en) | 1997-09-25 | 1998-09-22 | Tetrahydrofuran phosphate- and hydroxy esters as prodrugs for the corrersponding antifungal agent |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1027349B1 (xx) |
| JP (1) | JP3473949B2 (xx) |
| KR (1) | KR20010024297A (xx) |
| CN (1) | CN1125066C (xx) |
| AR (1) | AR015458A1 (xx) |
| AT (1) | ATE286502T1 (xx) |
| AU (1) | AU1698199A (xx) |
| BR (1) | BR9812671A (xx) |
| CA (1) | CA2304624C (xx) |
| CO (1) | CO5011088A1 (xx) |
| DE (1) | DE69828524T2 (xx) |
| ES (1) | ES2232974T3 (xx) |
| HK (1) | HK1025960A1 (xx) |
| HU (1) | HUP0004616A3 (xx) |
| ID (1) | ID28294A (xx) |
| IL (1) | IL134469A0 (xx) |
| MY (1) | MY133775A (xx) |
| NO (1) | NO20001557L (xx) |
| NZ (1) | NZ502709A (xx) |
| PE (1) | PE120799A1 (xx) |
| PL (1) | PL339488A1 (xx) |
| PT (1) | PT1027349E (xx) |
| SK (1) | SK3912000A3 (xx) |
| TR (1) | TR200000753T2 (xx) |
| WO (1) | WO1999015522A1 (xx) |
| ZA (1) | ZA988688B (xx) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000030655A1 (en) | 1998-11-20 | 2000-06-02 | Bristol-Myers Squibb Company | Water soluble prodrugs of azole compounds |
| US9040539B2 (en) * | 2010-05-19 | 2015-05-26 | Sandoz Ag | Process for the preparation of chiral triazolones |
| CN111138421A (zh) * | 2019-12-26 | 2020-05-12 | 上海英诺富成生物科技有限公司 | 抗真菌水溶性化合物及其制备方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0736030T3 (da) * | 1993-12-21 | 2001-10-29 | Schering Corp | Fungicide tetrahydrofuraner |
| US5693626A (en) * | 1993-12-21 | 1997-12-02 | Schering Corporation | Tetrahydrofuran antifungals |
-
1998
- 1998-09-22 AT AT98961721T patent/ATE286502T1/de not_active IP Right Cessation
- 1998-09-22 SK SK391-2000A patent/SK3912000A3/sk unknown
- 1998-09-22 PT PT98961721T patent/PT1027349E/pt unknown
- 1998-09-22 PL PL98339488A patent/PL339488A1/xx unknown
- 1998-09-22 TR TR2000/00753T patent/TR200000753T2/xx unknown
- 1998-09-22 BR BR9812671-7A patent/BR9812671A/pt not_active IP Right Cessation
- 1998-09-22 CA CA002304624A patent/CA2304624C/en not_active Expired - Fee Related
- 1998-09-22 IL IL13446998A patent/IL134469A0/xx unknown
- 1998-09-22 CN CN98809550A patent/CN1125066C/zh not_active Expired - Fee Related
- 1998-09-22 EP EP98961721A patent/EP1027349B1/en not_active Expired - Lifetime
- 1998-09-22 ES ES98961721T patent/ES2232974T3/es not_active Expired - Lifetime
- 1998-09-22 WO PCT/US1998/018508 patent/WO1999015522A1/en not_active Application Discontinuation
- 1998-09-22 NZ NZ502709A patent/NZ502709A/en unknown
- 1998-09-22 HU HU0004616A patent/HUP0004616A3/hu unknown
- 1998-09-22 MY MYPI98004343A patent/MY133775A/en unknown
- 1998-09-22 DE DE69828524T patent/DE69828524T2/de not_active Expired - Lifetime
- 1998-09-22 PE PE1998000905A patent/PE120799A1/es not_active Application Discontinuation
- 1998-09-22 ZA ZA988688A patent/ZA988688B/xx unknown
- 1998-09-22 KR KR1020007003196A patent/KR20010024297A/ko not_active Application Discontinuation
- 1998-09-22 AR ARP980104741A patent/AR015458A1/es unknown
- 1998-09-22 AU AU16981/99A patent/AU1698199A/en not_active Abandoned
- 1998-09-22 JP JP2000512827A patent/JP3473949B2/ja not_active Expired - Fee Related
- 1998-09-22 ID IDW20000551A patent/ID28294A/id unknown
- 1998-09-23 CO CO98055163A patent/CO5011088A1/es unknown
-
2000
- 2000-03-24 NO NO20001557A patent/NO20001557L/no not_active Application Discontinuation
- 2000-08-17 HK HK00105167A patent/HK1025960A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69828524T2 (de) | 2005-12-29 |
| AU1698199A (en) | 1999-04-12 |
| BR9812671A (pt) | 2000-08-22 |
| ID28294A (id) | 2001-05-10 |
| HK1025960A1 (en) | 2000-12-01 |
| PT1027349E (pt) | 2005-05-31 |
| NO20001557D0 (no) | 2000-03-24 |
| EP1027349B1 (en) | 2005-01-05 |
| SK3912000A3 (en) | 2000-08-14 |
| ZA988688B (en) | 1999-03-23 |
| PE120799A1 (es) | 1999-12-01 |
| HUP0004616A3 (en) | 2002-04-29 |
| AR015458A1 (es) | 2001-05-02 |
| DE69828524D1 (de) | 2005-02-10 |
| JP2001517665A (ja) | 2001-10-09 |
| JP3473949B2 (ja) | 2003-12-08 |
| KR20010024297A (ko) | 2001-03-26 |
| NZ502709A (en) | 2001-11-30 |
| HUP0004616A2 (hu) | 2002-03-28 |
| WO1999015522A1 (en) | 1999-04-01 |
| TR200000753T2 (tr) | 2001-01-22 |
| CA2304624A1 (en) | 1999-04-01 |
| CN1125066C (zh) | 2003-10-22 |
| PL339488A1 (en) | 2000-12-18 |
| CN1271356A (zh) | 2000-10-25 |
| NO20001557L (no) | 2000-03-24 |
| CA2304624C (en) | 2007-06-19 |
| ES2232974T3 (es) | 2005-06-01 |
| MY133775A (en) | 2007-11-30 |
| CO5011088A1 (es) | 2001-02-28 |
| EP1027349A1 (en) | 2000-08-16 |
| ATE286502T1 (de) | 2005-01-15 |
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