PA8524501A1 - Antibioticos macrolidos - Google Patents

Antibioticos macrolidos

Info

Publication number
PA8524501A1
PA8524501A1 PA20018524501A PA8524501A PA8524501A1 PA 8524501 A1 PA8524501 A1 PA 8524501A1 PA 20018524501 A PA20018524501 A PA 20018524501A PA 8524501 A PA8524501 A PA 8524501A PA 8524501 A1 PA8524501 A1 PA 8524501A1
Authority
PA
Panama
Prior art keywords
compounds
birds
mammals
fish
treatment
Prior art date
Application number
PA20018524501A
Other languages
English (en)
Inventor
Yan Chen
Wei-Guo Su
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PA8524501A1 publication Critical patent/PA8524501A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN ANTIBIÓTICO MACRÓLIDO DE LA FORMULA EN DONDE LAS VARIABLES SE DEFINEN COMO SE DESCRIBE AQUÍ. ESTOS MACRÓLIDOS SON ÚTILES COMO AGENTES ANTIBACTERIANOS Y ANTIPROTOZOARIOS EN MAMÍFEROS, INCLUIDO EL HOMBRE, ASÍ COMO PECES Y AVES; PARA EL TRATAMIENTO DE ENFERMEDADES INFECCIOSAS, INCLUYENDO AQUELLAS CAUSADAS POR ORGANISMOS QUE HAN RESULTADO RESISTENTES A OTROS ANTIBIÓTICOS. ESTA INVENCIÓN SE REFIERE TAMBIÉN A PROCEDIMIENTOS PARA PREPARAR LOS COMPUESTOS, INTERMEDIARIOS ÚTILES EN LA PREPARACIÓN DE LOS COMPUESTOS Y COMPOSICIONES FARMACÉUTICAS QUE CONTIENEN LOS COMPUESTOS. ADEMÁS, LA PRESENTE INVENCIÓN INCLUYE PROCEDIMIENTOS DE TRATAR INFECCIONES BACTERIANAS Y PROTOZOARIAS ADMINISTRANDO EL COMPUESTO EN MAMÍFEROS, PECES Y AVES QUE REQUIERAN DE DICHO TRATAMIENTO.
PA20018524501A 2000-08-07 2001-08-07 Antibioticos macrolidos PA8524501A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22359100P 2000-08-07 2000-08-07

Publications (1)

Publication Number Publication Date
PA8524501A1 true PA8524501A1 (es) 2002-08-29

Family

ID=22837162

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20018524501A PA8524501A1 (es) 2000-08-07 2001-08-07 Antibioticos macrolidos

Country Status (17)

Country Link
US (2) US20020115621A1 (es)
EP (1) EP1307468A1 (es)
JP (1) JP2004505987A (es)
AP (1) AP2001002236A0 (es)
AR (1) AR034695A1 (es)
AU (1) AU2001272719A1 (es)
BR (1) BR0112863A (es)
CA (1) CA2419044A1 (es)
DO (1) DOP2001000228A (es)
GT (1) GT200100159A (es)
HN (1) HN2001000176A (es)
MX (1) MXPA03001148A (es)
PA (1) PA8524501A1 (es)
PE (1) PE20020468A1 (es)
TN (1) TNSN01121A1 (es)
UY (1) UY26870A1 (es)
WO (1) WO2002012260A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200100613A (et) 1999-05-24 2003-02-17 Pfizer Products Inc. 13-metüülerütromütsiini derivaadid
MXPA02009587A (es) * 2000-03-28 2003-05-14 Biochemie Gmbh Particulas granuladas con sabor enmascarado.
AU2003234650A1 (en) * 2002-05-31 2003-12-19 Janssen Pharmaceutica N.V. 3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide antibacterial agents
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
EP2772254A3 (en) 2003-03-10 2015-03-11 Optimer Pharmaceuticals, Inc. Novel Antibacterial Agents
GB0310981D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20080287376A1 (en) * 2004-07-28 2008-11-20 Mohammad Salman Ketolide Derivatives as Antibacterial Agents
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
US20090170790A1 (en) * 2004-10-25 2009-07-02 Biswajit Das Ketolide derivatives as antibacterial agents
AP2007004026A0 (en) * 2004-12-21 2007-06-30 Pfizer Prod Inc Macrolides
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
ATE419261T1 (de) * 2005-01-13 2009-01-15 Glaxosmithkline Zagreb Decladinosyl-macrolide mit entzündungshemmender wirkung
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
EP1957508A2 (en) * 2005-11-23 2008-08-20 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
JP2009539866A (ja) * 2006-06-05 2009-11-19 オースペックス・ファーマシューティカルズ・インコーポレイテッド 置換エリスロマイシンアナログの調製および有用性
JP5698979B2 (ja) * 2007-10-25 2015-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド系抗菌剤の調製プロセス
CN105616437A (zh) * 2008-10-24 2016-06-01 森普拉制药公司 使用含三唑的大环内酯的生物防御
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN108310000A (zh) 2009-09-10 2018-07-24 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
EP3009442B1 (en) 2010-03-22 2019-06-19 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
DK2571506T3 (en) 2010-05-20 2017-08-28 Cempra Pharmaceuticals Inc PROCEDURES FOR THE MANUFACTURE OF MACROLIDES AND KETOLIDES AND INTERMEDIATES
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
RU2658050C2 (ru) 2012-03-27 2018-06-19 Семпра Фармасьютикалз, Инк. Парентеральные составы для введения макролидных антибиотиков
JP6426696B2 (ja) 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
CA2907085A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US61857A (en) 1867-02-05 Improvement in top-drivers or spinners
US156027A (en) 1874-10-20 Improvement in loom-shuttles
US100518A (en) 1870-03-08 Roland s
US40007A (en) 1863-09-22 Improvement in railroad-car brakes
US61856A (en) 1867-02-05 Enos s
US25937A (en) 1859-11-01 ballou
US3923784A (en) * 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
US5523399A (en) 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2745290B1 (fr) * 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
US5804565A (en) * 1996-09-24 1998-09-08 Taisho Pharmaceutical Co., Ltd. Erythromycin A derivatives
CZ180799A3 (cs) * 1996-11-27 1999-09-15 Taisho Pharmaceutical Co., Ltd. Deriváty erythromycinu A
US6162794A (en) * 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
PA8461401A1 (es) * 1997-10-29 2000-05-24 Pfizer Prod Inc Derivados de eritromicina triciclicos
ZA989835B (en) 1997-10-29 1999-05-05 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
AU9649698A (en) 1997-10-29 1999-05-17 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
CN1284961A (zh) * 1997-12-11 2001-02-21 北陆制药株式会社 红霉素衍生物
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
WO1999062920A1 (en) * 1998-06-03 1999-12-09 Pfizer Products Inc. Tricyclic 3-keto derivatives of 6-o-methylerythromycin
SI1147121T1 (en) 1999-01-27 2004-04-30 Pfizer Products Inc. Ketolide antibiotics
WO2001010878A1 (fr) 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO2001010880A1 (fr) 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6498146B1 (en) * 1999-10-28 2002-12-24 Pfizer Inc Erythromycin derivatives
EP1101769A3 (en) * 1999-11-18 2001-10-24 Pfizer Products Inc. Nitrogen containing erythromycin derivatives

Also Published As

Publication number Publication date
CA2419044A1 (en) 2002-02-14
GT200100159A (es) 2002-03-22
US20040009930A1 (en) 2004-01-15
US6849608B2 (en) 2005-02-01
US20020115621A1 (en) 2002-08-22
MXPA03001148A (es) 2003-06-09
UY26870A1 (es) 2002-03-22
AR034695A1 (es) 2004-03-17
AU2001272719A1 (en) 2002-02-18
BR0112863A (pt) 2003-07-01
JP2004505987A (ja) 2004-02-26
PE20020468A1 (es) 2002-06-14
HN2001000176A (es) 2001-10-08
DOP2001000228A (es) 2002-09-30
EP1307468A1 (en) 2003-05-07
WO2002012260A1 (en) 2002-02-14
TNSN01121A1 (fr) 2005-11-10
AP2001002236A0 (en) 2001-09-30

Similar Documents

Publication Publication Date Title
PA8524501A1 (es) Antibioticos macrolidos
UY25330A1 (es) Nuevos macrólidos
GT199900192A (es) Nuevos antibioticos macrolidos.
ATE311209T1 (de) Kombinationen von antiseptischen und antibiotischen mitteln enthaltende medizinische vorrichtungen
BRPI0413372A (pt) composto e composições de nitrofuranos de quinazolinil halogenados, seus métodos de preparação e usos como agentes antibacterianos
GT199900198A (es) Azalidas de 13 miembros y su uso como agentes antibioticos.
CO7250441A2 (es) Inhibidores de girasa y uso de los mismos
GT199800075A (es) Derivados de macrolidos c-4" sustituidos.
ES2188795T3 (es) Agentes antimicrobianos benzoxacina.
BRPI0618374A2 (pt) uso de um composto ou um derivado do mesmo farmaceuticamente aceitável, métodos para matar microorganismos clinicamente latentes em um mamìfero, para tratar ou prevenir uma infecção microbiana em um mamìfero, para esterilizar um objeto, para preservar um material inorgánico ou orgánico, para tratar uma doença, para reduzir a dose de agente antimicrobiano convencional requerida para tratar uma infecção microbiana e para tratar uma doença de protozoário em um mamìfero, produto combinado, formulação, uso de um produto combinado, composto, e, processo para a preparação do mesmo
GT199800074A (es) Derivados de la 9-oxima eritromicina.
HUP9900492A2 (hu) 3,6-Ketál és enol-éter makrolid antibiotikumok és ezeket tartalmazó gyógyszerkészítmények
ECSP055980A (es) Oxazolidinonas de indolona y derivados de las mismas
CL2021002263A1 (es) Compuestos antibacterianos (solicitud divisional 202001147)
AR043824A1 (es) Composiciones y metodo para tratar las infecciones microbianas y parasitarias en el ganado y otros animales
ES2163186T3 (es) Composicion que comprende mupirocina y clorhexidina.
AR029420A1 (es) Derivados de piperidiniloxi y pirrolidiniloxi oxazolidinona, un procedimiento para su preparacion, intermediarios y el uso de dichos derivados para la fabricacion de un medicamento antibacteriano
ES2178761T3 (es) Utilizacion de 1-hidroxi-2-piridonas para el tratamiento de infe cciones cutaneas.
BRPI0413413A (pt) feniloxazolidinonas de piperidino substituìdo tendo atividade antimicrobiana com eficácia in vivo melhorada
GT199800162A (es) Derivados de eritromicina triciclicos.
AR025379A1 (es) 9a-azalidas con actividad antibacteriana.
ES2108149T3 (es) Derivado de cefalosporina.
BR0100228A (pt) Macrolìdeos com 13 e 14 elementos antibacterianos e procinéticos e seus intermediários
GT200000185A (es) Derivados de higromicina.
GT199600072A (es) Formas zwitterionicas de trovafloxacina.