TNSN01121A1 - Antibiotiques nouveaux faisant partie des macrolides, et compositions les contenant - Google Patents

Antibiotiques nouveaux faisant partie des macrolides, et compositions les contenant

Info

Publication number
TNSN01121A1
TNSN01121A1 TNTNSN01121A TNSN01121A TNSN01121A1 TN SN01121 A1 TNSN01121 A1 TN SN01121A1 TN TNSN01121 A TNTNSN01121 A TN TNSN01121A TN SN01121 A TNSN01121 A TN SN01121A TN SN01121 A1 TNSN01121 A1 TN SN01121A1
Authority
TN
Tunisia
Prior art keywords
compositions containing
antibiotics including
novel antibiotics
including macrolides
macrolides
Prior art date
Application number
TNTNSN01121A
Other languages
English (en)
Inventor
Chen Yan
Su Wei-Guo
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN01121A1 publication Critical patent/TNSN01121A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'INVENTION CONCERNE UN ANTIBIOTIQUE MACROLIDE DE FORMULE (I) : DANS LAQUELLE R1, R2, R3, R4, R5, R6, R7, R8, X ET Z REPRESENTENT DIVERS RADICAUX. ELLE CONCERNE EGALEMENT UN PROCEDE POUR SA PREPARATION, ET UNE COMPOSITION PHARMACEUTIQUE LE CONTENANT. APPLICATION : UTILISATION DE CE COMPOSE OU DE CETTE COMPOSITION POUR LE TRAITEMENT D'INFECTIONS BACTERIENNES OU D'INFECTIONS PAR DES PROTOZOAIRES, CHEZ DES MAMMIFERES, DES POISSONS OU DES OISEAUX.
TNTNSN01121A 2000-08-07 2001-08-06 Antibiotiques nouveaux faisant partie des macrolides, et compositions les contenant TNSN01121A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22359100P 2000-08-07 2000-08-07

Publications (1)

Publication Number Publication Date
TNSN01121A1 true TNSN01121A1 (fr) 2005-11-10

Family

ID=22837162

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN01121A TNSN01121A1 (fr) 2000-08-07 2001-08-06 Antibiotiques nouveaux faisant partie des macrolides, et compositions les contenant

Country Status (17)

Country Link
US (2) US20020115621A1 (fr)
EP (1) EP1307468A1 (fr)
JP (1) JP2004505987A (fr)
AP (1) AP2001002236A0 (fr)
AR (1) AR034695A1 (fr)
AU (1) AU2001272719A1 (fr)
BR (1) BR0112863A (fr)
CA (1) CA2419044A1 (fr)
DO (1) DOP2001000228A (fr)
GT (1) GT200100159A (fr)
HN (1) HN2001000176A (fr)
MX (1) MXPA03001148A (fr)
PA (1) PA8524501A1 (fr)
PE (1) PE20020468A1 (fr)
TN (1) TNSN01121A1 (fr)
UY (1) UY26870A1 (fr)
WO (1) WO2002012260A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003500414A (ja) 1999-05-24 2003-01-07 ファイザー・プロダクツ・インク １３−メチルエリスロマイシン誘導体
DE60138876D1 (de) * 2000-03-28 2009-07-16 Sandoz Ag Geschmackmaskierte granulierte teilchen
US6825172B2 (en) 2002-05-31 2004-11-30 Janssen Pharmaceutica, Nv 3-descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
GB0310981D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
WO2005030227A1 (fr) 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. Derives 9a-azalide 11-3c-bicycliques
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
BRPI0513903A (pt) * 2004-07-28 2008-05-20 Ranbaxy Lab Ltd derivados de cetolìdeos úteis como agentes antimicrobianos, seus processos de preparação e composições farmacêuticas compreendendo os mesmos
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
WO2006046112A2 (fr) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Derives de cetolides utiles comme agents antibacteriens
EP2233493A1 (fr) * 2004-12-21 2010-09-29 Pfizer Products Inc. Macrolides
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
DE602006004555D1 (de) 2005-01-13 2009-02-12 Glaxosmithkline Zagreb Decladinosyl-macrolide mit entzündungshemmender wirkung
US20090130225A1 (en) * 2005-11-23 2009-05-21 Anjan Chakrabarti Macrolides derivatives as antibacterial agents
WO2007060518A2 (fr) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Dérivés de cétolide en tant qu'agents antibactériens
WO2007143507A2 (fr) * 2006-06-05 2007-12-13 Auspex Pharmaceuticals, Inc. Préparation et utilité d'analogues d'érythromycine substitués
WO2009055557A1 (fr) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Procédé pour la préparation d'agents antibactériens macrolides
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) * 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
WO2011119604A1 (fr) 2010-03-22 2011-09-29 Cempra Pharmaceuticals, Inc. Formes cristallines d'un macrolide et leurs utilisations
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
CA2868262A1 (fr) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Formulations parenterales pour l'administration d'antibiotiques macrolides
CN105163785A (zh) 2013-03-14 2015-12-16 森普拉制药公司 用于治疗呼吸道疾病的方法及其制剂
CA2907085A1 (fr) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Procedes convergents de preparation d'agents antibacteriens macrolides

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US100518A (en) 1870-03-08 Roland s
US40007A (en) 1863-09-22 Improvement in railroad-car brakes
US61857A (en) 1867-02-05 Improvement in top-drivers or spinners
US61856A (en) 1867-02-05 Enos s
US156027A (en) 1874-10-20 Improvement in loom-shuttles
US25937A (en) 1859-11-01 ballou
US3923784A (en) 1973-09-10 1975-12-02 Hoffmann La Roche Erythromycin a derivatives
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
US5523399A (en) 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2745290B1 (fr) 1996-02-28 1998-04-03 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2748746B1 (fr) 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
US5804565A (en) 1996-09-24 1998-09-08 Taisho Pharmaceutical Co., Ltd. Erythromycin A derivatives
CN1238777A (zh) 1996-11-27 1999-12-15 大正制药株式会社 红霉素a衍生物
AU6932098A (en) 1997-05-09 1998-12-08 Pfizer Products Inc. Erythromycin derivatives
EP0895999A1 (fr) 1997-08-06 1999-02-10 Pfizer Products Inc. Macrolides antibiotiques substitués C"-4
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
JP2004514643A (ja) 1997-10-29 2004-05-20 大正製薬株式会社 エリスロマイシンａ誘導体
PA8461401A1 (es) 1997-10-29 2000-05-24 Pfizer Prod Inc Derivados de eritromicina triciclicos
ZA989835B (en) 1997-10-29 1999-05-05 Taisho Pharmaceutical Co Ltd Erythromycin a derivatives
HN1998000159A (es) 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
CN1284961A (zh) * 1997-12-11 2001-02-21 北陆制药株式会社 红霉素衍生物
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
WO1999062920A1 (fr) 1998-06-03 1999-12-09 Pfizer Products Inc. Derives 3-keto tricycliques de 6-o-methylerythromycine
HUP0105190A3 (en) 1999-01-27 2003-03-28 Pfizer Prod Inc Ketolide antibiotics, medicaments containing them and their use
WO2001010878A1 (fr) 1999-08-06 2001-02-15 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
AU6183800A (en) 1999-08-06 2001-03-05 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
US6498146B1 (en) * 1999-10-28 2002-12-24 Pfizer Inc Erythromycin derivatives
EP1101769A3 (fr) 1999-11-18 2001-10-24 Pfizer Products Inc. Dérivés de l'érythromycine contenant de l'azote

Also Published As

Publication number Publication date
BR0112863A (pt) 2003-07-01
GT200100159A (es) 2002-03-22
PE20020468A1 (es) 2002-06-14
DOP2001000228A (es) 2002-09-30
CA2419044A1 (fr) 2002-02-14
HN2001000176A (es) 2001-10-08
US6849608B2 (en) 2005-02-01
AP2001002236A0 (en) 2001-09-30
AU2001272719A1 (en) 2002-02-18
PA8524501A1 (es) 2002-08-29
JP2004505987A (ja) 2004-02-26
EP1307468A1 (fr) 2003-05-07
MXPA03001148A (es) 2003-06-09
US20020115621A1 (en) 2002-08-22
US20040009930A1 (en) 2004-01-15
AR034695A1 (es) 2004-03-17
UY26870A1 (es) 2002-03-22
WO2002012260A1 (fr) 2002-02-14

Similar Documents

Publication Publication Date Title
TNSN01121A1 (fr) Antibiotiques nouveaux faisant partie des macrolides, et compositions les contenant
TNSN99205A1 (fr) Macrolides antibiotiques nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
TNSN98238A1 (fr) Macrolides nouveaux
TNSN98194A1 (fr) Derives nouveaux de 6-o-methylerythromycine a, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN98082A1 (fr) DERIVES SUBSTITUES EN C - 4 DE 9 - DESOXO - 9a - aza - 9a HOMOERYTHROMYCINE A.
TNSN00191A1 (fr) Composes nouveaux, compositions les contenant et leur utilisation dans le traitement d'une ischemie
MA26717A1 (fr) Macrolides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN01091A1 (fr) Derives bicycliques nouveaux, compositions les contenant et leur utilisation pour le traitement d'une croissance cellulaire anormale
TNSN00108A1 (fr) Derives d'erythromycine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN99214A1 (fr) Azalides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
TNSN99106A1 (fr) Derives d'isothiazole nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
TNSN99236A1 (fr) Derives bicycliques substitues nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
TNSN00092A1 (fr) Composes nouveaux antagonistes de npy, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN99172A1 (fr) 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinoleines, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN00028A1 (fr) Derives de quinoleine -2-one a substituant heteroaryle nouveaux procede pour leur preparation et compositions pharmaceutiques les contenant.
TNSN99095A1 (fr) 4 - phenylpiperidines nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN98084A1 (fr) Derives de macrolides substitues en position c-4
BG104640A (en) Novel erythromycin derivatives
TNSN99227A1 (fr) Macrolides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant
TNSN01126A1 (fr) Imidazoles substitues nouveaux, procede pour leur preparation et compositions les contenant
TNSN01046A1 (fr) Ethers de diphenyle utiles en therapeutique
TNSN98196A1 (fr) Derives d'erythromycine tricycliques nouveaux, procede pour leur preparation et compositions les contenant
TNSN00250A1 (fr) Composes nouveaux inhibiteurs de pcp, procede pour leur preparation et compositions les contenant
TNSN99111A1 (fr) Derives de sulfonylbenzene nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
ES2159733T3 (es) Compuestos de dialquiltiacumicina.