TNSN99227A1 - Macrolides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Macrolides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
TNSN99227A1
TNSN99227A1 TNTNSN99227A TNSN99227A TNSN99227A1 TN SN99227 A1 TNSN99227 A1 TN SN99227A1 TN TNSN99227 A TNTNSN99227 A TN TNSN99227A TN SN99227 A TNSN99227 A TN SN99227A TN SN99227 A1 TNSN99227 A1 TN SN99227A1
Authority
TN
Tunisia
Prior art keywords
pharmaceutical compositions
compositions containing
compounds
formula
preparation
Prior art date
Application number
TNTNSN99227A
Other languages
English (en)
Inventor
Kaneko Takushi
Su Wei-Guo
Wu Yong-Jin
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TNSN99227A1 publication Critical patent/TNSN99227A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'INVENTION CONCERNE DES COMPOSES DE FORMULE 1 : DANS LAQUELLE X1, X2, R2, R15, R16 ET R6 REPRESENTENT DIVERS RADICAUX. ELLE CONCERNE EGALEMENT UN PROCEDE POUR LEUR PREPARATION ET DES COMPOSITIONS PHARMACEUTIQUES LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS POUR LE TRAITEMENT D'INFECTIONS BACTERIENNES ET D'INFECTIONS PAR DES PROTOZOAIRES
TNTNSN99227A 1998-12-10 1999-12-02 Macrolides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant TNSN99227A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11172898P 1998-12-10 1998-12-10

Publications (1)

Publication Number Publication Date
TNSN99227A1 true TNSN99227A1 (fr) 2005-11-10

Family

ID=22340138

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN99227A TNSN99227A1 (fr) 1998-12-10 1999-12-02 Macrolides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant

Country Status (13)

Country Link
US (1) US6664238B1 (fr)
EP (1) EP1137654A1 (fr)
AT (1) ATE344269T1 (fr)
AU (1) AU6484199A (fr)
DE (1) DE69933897T2 (fr)
ES (1) ES2273964T3 (fr)
GT (1) GT199900208A (fr)
MA (1) MA26711A1 (fr)
PA (1) PA8486401A1 (fr)
PE (1) PE20001297A1 (fr)
TN (1) TNSN99227A1 (fr)
TR (1) TR200102129T2 (fr)
WO (1) WO2000034297A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2243066T3 (es) 1998-09-22 2005-11-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
BR9916969A (pt) * 1999-01-27 2001-11-06 Pfizer Prod Inc Antibióticos cetólidos
ES2272273T3 (es) 1999-04-16 2007-05-01 Kosan Biosciences, Inc. Agentes antiinfecciosos macrolidos.
AU4354900A (en) 1999-04-16 2000-11-02 Kosan Biosciences, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
CA2529817C (fr) 2003-03-10 2013-02-12 Optimer Pharmaceuticals, Inc. Nouveaux agents antibacteriens
US7419962B2 (en) * 2004-12-07 2008-09-02 Enanta Pharmaceuticals, Inc. 3,6-bicyclolides
EP1836211B1 (fr) * 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
CN1318441C (zh) * 2005-04-25 2007-05-30 中国医学科学院医药生物技术研究所 大环内酯类抗生素的酮内酯化合物及其制备方法和用途
EP1957508A2 (fr) * 2005-11-23 2008-08-20 Ranbaxy Laboratories Limited Dérivés de cétolide en tant qu'agents antibactériens
CN101917850B (zh) 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
WO2010048599A1 (fr) 2008-10-24 2010-04-29 Cempra Pharmaceuticals, Inc. Procédés de traitement de maladies gastro-intestinales
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
NZ602544A (en) 2010-03-22 2014-11-28 Cempra Pharmaceuticals Inc Crystalline forms of a macrolide, and uses therefor
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
SG11201405895UA (en) 2012-03-27 2014-10-30 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
JP6675973B2 (ja) 2013-03-15 2020-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗菌薬を調製するための集束的な方法
CN114437154B (zh) * 2022-01-30 2024-03-01 北京理工大学 一种含有喹诺酮的酮内酯衍生物及其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
IL99995A (en) 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2718450B1 (fr) 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
DE19626036A1 (de) 1996-06-28 1998-01-02 Whitaker Corp Optischer Steckverbinder
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
BR9713302A (pt) 1996-11-27 2000-03-21 Taisho Pharmaceutical Co Ltd Derivado de eritromicina a, composição farmacêutica, preparação antibacteriana, processo para o tratamento de uma doença bacteriologicamente infecciosa, e, uso do derivado de eritromicina a ou um seu sal farcamaceuticamente aceitável.
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5794778A (en) 1997-02-26 1998-08-18 Riverwood International Corporation Article carrier with strap-type handle and top panel access
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
ATE344269T1 (de) 2006-11-15
PE20001297A1 (es) 2000-12-04
US6664238B1 (en) 2003-12-16
WO2000034297A1 (fr) 2000-06-15
DE69933897D1 (de) 2006-12-14
EP1137654A1 (fr) 2001-10-04
PA8486401A1 (es) 2003-01-24
ES2273964T3 (es) 2007-05-16
DE69933897T2 (de) 2007-03-15
GT199900208A (es) 2001-05-31
TR200102129T2 (tr) 2002-01-21
MA26711A1 (fr) 2004-12-20
AU6484199A (en) 2000-06-26

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