PA8461101A1 - Uso de un antagonista del receptor 5-ht3 en el tratamiento del sindrome del intestino irritable (ibs) - Google Patents

Uso de un antagonista del receptor 5-ht3 en el tratamiento del sindrome del intestino irritable (ibs)

Info

Publication number
PA8461101A1
PA8461101A1 PA19988461101A PA8461101A PA8461101A1 PA 8461101 A1 PA8461101 A1 PA 8461101A1 PA 19988461101 A PA19988461101 A PA 19988461101A PA 8461101 A PA8461101 A PA 8461101A PA 8461101 A1 PA8461101 A1 PA 8461101A1
Authority
PA
Panama
Prior art keywords
ibs
treatment
receptor antagonist
intestine syndrome
irritable intestine
Prior art date
Application number
PA19988461101A
Other languages
English (en)
Inventor
Allen Wayne Mangel
Allison Ruth Northcutt
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10820099&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8461101(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of PA8461101A1 publication Critical patent/PA8461101A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

LA PRESENTE INVENCION SE REFIERE AL USO DE UN ANTAGONISTA DEL RECEPTOR DE 5-HT3 EN EL TRATAMIENTO DE PACIENTES FEMENINOS CON IBS NO CONSTIPADOS.
PA19988461101A 1997-10-07 1998-10-05 Uso de un antagonista del receptor 5-ht3 en el tratamiento del sindrome del intestino irritable (ibs) PA8461101A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9721139.5A GB9721139D0 (en) 1997-10-07 1997-10-07 Medicaments

Publications (1)

Publication Number Publication Date
PA8461101A1 true PA8461101A1 (es) 2000-05-24

Family

ID=10820099

Family Applications (1)

Application Number Title Priority Date Filing Date
PA19988461101A PA8461101A1 (es) 1997-10-07 1998-10-05 Uso de un antagonista del receptor 5-ht3 en el tratamiento del sindrome del intestino irritable (ibs)

Country Status (36)

Country Link
US (3) US6284770B1 (es)
EP (1) EP1021174A2 (es)
JP (1) JP2001518495A (es)
KR (1) KR20010015707A (es)
CN (1) CN1281357A (es)
AP (1) AP2000001785A0 (es)
AR (1) AR017296A1 (es)
AU (1) AU750818B2 (es)
BR (1) BR9812886A (es)
CA (1) CA2305751A1 (es)
CO (1) CO5011096A1 (es)
DZ (1) DZ2618A1 (es)
EA (1) EA003184B1 (es)
EE (1) EE200000214A (es)
GB (1) GB9721139D0 (es)
GT (1) GT199800157A (es)
HN (1) HN1998000155A (es)
HR (1) HRP20000198A2 (es)
HU (1) HUP0003750A3 (es)
ID (1) ID23874A (es)
IL (1) IL135398A0 (es)
IS (1) IS5425A (es)
MA (1) MA26549A1 (es)
NO (1) NO20001776L (es)
NZ (1) NZ503698A (es)
PA (1) PA8461101A1 (es)
PE (1) PE120299A1 (es)
PL (1) PL340337A1 (es)
SK (1) SK4862000A3 (es)
SV (1) SV1998000122A (es)
TN (1) TNSN98179A1 (es)
TR (1) TR200000913T2 (es)
UY (1) UY25200A1 (es)
WO (1) WO1999017755A2 (es)
YU (1) YU20600A (es)
ZA (1) ZA989061B (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9721139D0 (en) 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments
US7767203B2 (en) * 1998-08-07 2010-08-03 Ganeden Biotech, Inc. Methods for the dietary management of irritable bowel syndrome and carbohydrate malabsorption
US6136807A (en) * 1998-11-10 2000-10-24 3M Innovative Properties Company Composition for the transdermal delivery of lerisetron
EP1090638A1 (en) * 1999-10-08 2001-04-11 Sanofi-Synthelabo Use of (R)-zacopride or a salt thereof for the manufacture of a medicament for the treatment of sleep apnea
TWI263496B (en) * 1999-12-10 2006-10-11 Novartis Ag Pharmaceutical combinations and their use in treating gastrointestinal disorders
DE10015783C2 (de) * 2000-03-30 2003-12-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Lerisetron und seine Verwendung
EP1284732A2 (en) * 2000-05-18 2003-02-26 Glaxo Group Limited Method for treating functional dyspepsia using alosetron
AR028970A1 (es) * 2000-07-26 2003-05-28 Solvay Pharm Gmbh USO DE CILANSETRON O DE SUS SALES POR ADICIoN DE A CIDOS Y/O SOLVATOS FARMACOLoGICAMENTE COMPATIBLES PARA LA OBTENCIoN DE PREPARADOS FARMACEUTICOS PARA EL TRATAMIENTO Y/O LA PROFILAXIS DEL SíNDROME DEL INTESTINO IRRITABLE
US6566369B2 (en) 2000-07-26 2003-05-20 Solvay Pharmaceuticals Gmbh Medicament containing cilansetron for the treatment of non-obstipative male irritable bowel syndrome patients
JP2004508056A (ja) * 2000-09-06 2004-03-18 グラクソ グループ リミテッド 5−ヒドロキシトリプタミン受容体遺伝子多型、および治療に対する応答
US20040048874A1 (en) * 2001-05-22 2004-03-11 Bardsley Hazel Judith New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
GB0216027D0 (en) * 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
DK1395289T3 (da) * 2001-06-07 2011-03-28 Christine Dr Sang Behandling af neuropatisk smerte med en N-methyl-D-aspartat- (NMDA-)receptorantagonist
US7045549B2 (en) 2001-11-08 2006-05-16 The Board Of Trustees Of The Leland Stanford Jr. University Treatment of symptoms associated with irritable bowel syndrome
WO2003061657A1 (en) * 2002-01-18 2003-07-31 Aryx Therapeutics 5-ht3 receptor antagonists and methods of use
DE60326585D1 (de) * 2002-07-10 2009-04-23 Dynogen Pharmaceuticals Inc 4-(2-fluorophenyl)-6-methyl-2(1-piperazinyl)thieno(2,3-d) pyrimidin bei der behandlung von funktionalen darmstörungen
DE10232750A1 (de) * 2002-07-18 2004-02-05 Basf Ag Verfahren zur Herstellung von macrocyclischen Ketonen durch Dieckmann-Kondensation in der Gasphase
WO2004014428A1 (ja) * 2002-08-09 2004-02-19 Ajinomoto Co.,Inc. 腸疾患および内臓痛の治療薬
US20030187017A1 (en) * 2002-11-14 2003-10-02 Mangel Allen Wayne Method for treating functional dyspepsia
ATE359079T1 (de) * 2003-01-13 2007-05-15 Dynogen Pharmaceuticals Inc Verfahren zur behandlung von übelkeit, erbrechen, würgereiz oder jede kombination daraus
BRPI0406749A (pt) * 2003-01-13 2005-12-20 Dynogen Pharmaceuticals Inc Métodos relacionados ao tratamento de distúrbios fincionais do intestino e composição farmacêutica
JO2735B1 (en) 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formations of balloonosterone
ZA200409537B (en) * 2003-01-31 2006-10-25 Yamanouchi Pharma Co Ltd Stable solid medicinal composition for oral administration
EP1594493A2 (en) * 2003-12-16 2005-11-16 Teva Pharmaceutical Industries Ltd. Polymorphic forms of tegaserod base and salts thereof
JP3763360B2 (ja) * 2004-01-30 2006-04-05 アステラス製薬株式会社 下痢型過敏性腸症候群治療剤
WO2005072730A1 (ja) * 2004-01-30 2005-08-11 Astellas Pharma Inc. 下痢型過敏性腸症候群治療剤
WO2005073220A1 (ja) * 2004-01-30 2005-08-11 Yamanouchi Pharmaceutical Co., Ltd. 下痢型過敏性腸症候群治療剤
US7358270B2 (en) 2004-01-30 2008-04-15 Astellas Pharma Inc. Treating agent for irritable bowel syndrome
WO2005076824A2 (en) * 2004-02-03 2005-08-25 The Regents Of The University Of California Methods of treating irritable bowel syndrome
JP4559749B2 (ja) * 2004-02-16 2010-10-13 あすか製薬株式会社 ピペラジニルピリジン誘導体
JP4912145B2 (ja) * 2004-02-26 2012-04-11 あすか製薬株式会社 ピリミジン誘導体
JP2006028028A (ja) * 2004-07-12 2006-02-02 Teikoku Medix Kk 経口医薬組成物
US20060293309A1 (en) * 2005-03-28 2006-12-28 Dynogen Pharmaceuticals, Inc. Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
JP5086248B2 (ja) * 2005-06-07 2012-11-28 セラヴァンス, インコーポレーテッド 5−ht4受容体アゴニストとしてのベンゾイミダゾロン−カルボキサミド化合物
WO2007000046A1 (en) * 2005-06-27 2007-01-04 Holburn Biomedical Corporation Methods for diagnosing functional bowel disease
JP4632204B2 (ja) * 2005-09-21 2011-02-16 アステラス製薬株式会社 下痢型過敏性腸症候群治療剤
ZA200806983B (en) * 2006-02-20 2009-11-25 Astellas Pharma Inc Amide derivative or salt thereof
WO2009053750A2 (en) 2007-10-24 2009-04-30 Generics [Uk] Limited Novel crystalline and amorphous forms
WO2009053732A1 (en) 2007-10-24 2009-04-30 Generics [Uk] Limited Novel salt
WO2009053733A2 (en) 2007-10-24 2009-04-30 Generics [Uk] Limited Novel crystalline forms
WO2009053754A2 (en) 2007-10-24 2009-04-30 Generics [Uk] Limited Novel crystalline forms
US8734867B2 (en) * 2007-12-28 2014-05-27 Liveleaf, Inc. Antibacterial having an extract of pomegranate combined with hydrogen peroxide
SG10201502453SA (en) 2009-03-04 2015-05-28 Liveleaf Inc Method and material for site activated complexing of biologic molecules
EP2424550B1 (en) 2009-04-29 2017-06-07 Ganeden Biotech, Inc. Bacterial cell membrane formulation
WO2011001954A1 (ja) * 2009-06-30 2011-01-06 アステラス製薬株式会社 緩解期の炎症性腸疾患患者における排便異常治療剤
JP5938886B2 (ja) * 2010-12-14 2016-06-22 アステラス製薬株式会社 活動期の炎症性腸疾患患者における排便異常治療剤
US20120329736A1 (en) * 2011-06-24 2012-12-27 Huang Alexander L Treatment for gastrointestinal disorders using a selective, site-activated binding system
US8722040B2 (en) 2011-06-24 2014-05-13 Liveleaf, Inc. Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites
US9192635B2 (en) 2011-06-24 2015-11-24 Liveleaf, Inc. Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide
EP2744497B1 (en) * 2011-10-18 2016-04-06 Helsinn Healthcare SA Therapeutic combinations of netupitant and palonosetron
CN104768540A (zh) * 2012-09-05 2015-07-08 才思制药公司 抗胆碱能神经保护组合物和方法
US8716351B1 (en) 2012-12-23 2014-05-06 Liveleaf, Inc. Methods of treating gastrointestinal spasms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0254584B1 (en) * 1986-07-25 1992-10-07 Beecham Group Plc Azabicyclic compounds, process for their preparation, and their pharmaceutical use
GB8806990D0 (en) * 1988-03-23 1988-04-27 Beecham Group Plc Novel compounds
GB8701022D0 (en) 1987-01-19 1987-02-18 Beecham Group Plc Treatment
GB2209335B (en) 1987-09-03 1991-05-29 Glaxo Group Ltd Lactam derivatives
EP0315390B1 (en) * 1987-11-04 1994-07-20 Beecham Group Plc Novel 4-oxobenzotriazines and 4-oxoquinazolines
JPH0249772A (ja) * 1988-04-07 1990-02-20 Glaxo Group Ltd イミダゾール誘導体
GB8814277D0 (en) * 1988-06-16 1988-07-20 Glaxo Group Ltd Chemical compounds
US5017573A (en) * 1988-07-29 1991-05-21 Dainippon Pharmaceutical Co., Ltd. Indazole-3-carboxylic acid derivatives
GB8820650D0 (en) * 1988-09-01 1988-10-05 Glaxo Group Ltd Medicaments
GB8823980D0 (en) * 1988-10-13 1988-11-23 Glaxo Group Ltd Chemical compounds
GB8829079D0 (en) 1988-12-13 1989-01-25 Beecham Group Plc Novel compounds
GB8904551D0 (en) 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
EP0387431A1 (en) * 1989-03-14 1990-09-19 Beecham Group Plc Imidazole derivatives, process for their preparation and their pharmaceutical use
GB9020927D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Pharmaceuticals
GB9027098D0 (en) 1990-12-13 1991-02-06 Beecham Group Plc Pharmaceuticals
GB9027487D0 (en) * 1990-12-19 1991-02-06 Beecham Group Plc Pharmaceuticals
JPH06506443A (ja) * 1991-01-09 1994-07-21 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー アザ二環式およびアザ三環式誘導体、その製法および中間体ならびに該化合物含有の医薬組成物
GB9214184D0 (en) 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
GB9721139D0 (en) * 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
WO1999017755A2 (en) 1999-04-15
PL340337A1 (en) 2001-01-29
US20030036549A1 (en) 2003-02-20
EE200000214A (et) 2001-06-15
HUP0003750A2 (hu) 2001-10-28
PE120299A1 (es) 1999-12-15
AR017296A1 (es) 2001-09-05
TNSN98179A1 (fr) 2005-03-15
US6593336B2 (en) 2003-07-15
WO1999017755A3 (en) 1999-09-23
KR20010015707A (ko) 2001-02-26
UY25200A1 (es) 2001-01-31
YU20600A (sh) 2003-10-31
EP1021174A2 (en) 2000-07-26
US20010044450A1 (en) 2001-11-22
GB9721139D0 (en) 1997-12-03
NO20001776L (no) 2000-06-06
SK4862000A3 (en) 2001-01-18
IS5425A (is) 2000-03-31
US6429209B2 (en) 2002-08-06
EA200000299A1 (ru) 2000-12-25
DZ2618A1 (fr) 2003-03-01
AP2000001785A0 (en) 2000-06-30
ZA989061B (en) 2001-07-05
MA26549A1 (fr) 2004-12-20
HRP20000198A2 (en) 2001-04-30
AU750818B2 (en) 2002-07-25
JP2001518495A (ja) 2001-10-16
NZ503698A (en) 2002-10-25
CO5011096A1 (es) 2001-02-28
HUP0003750A3 (en) 2003-02-28
NO20001776D0 (no) 2000-04-06
BR9812886A (pt) 2000-08-08
EA003184B1 (ru) 2003-02-27
ID23874A (id) 2000-05-25
SV1998000122A (es) 1999-07-05
IL135398A0 (en) 2001-05-20
AU9629398A (en) 1999-04-27
US6284770B1 (en) 2001-09-04
CN1281357A (zh) 2001-01-24
TR200000913T2 (tr) 2001-01-22
HN1998000155A (es) 1999-05-24
GT199800157A (es) 2000-03-30
CA2305751A1 (en) 1999-04-15

Similar Documents

Publication Publication Date Title
PA8461101A1 (es) Uso de un antagonista del receptor 5-ht3 en el tratamiento del sindrome del intestino irritable (ibs)
CY1121113T1 (el) Θεραπεια της νοσου ρομρε
CY1119369T1 (el) Ιατρικα παρασκευασματα για τη θεραπευτικη αγωγη της ανεπαρκειας της αλφα-γαλακτοσιδασης α
IS6750A (is) Samrunnin heterósýklísk súkkínímíð efnasambönd oghliðstæður þeirra, stillar fyrir starfsemi kjarnahormónaviðtaka
PT1326643E (pt) Inibicao do efeito emetico da metformina com antagonistas de receptores 5-ht3
EA200100780A1 (ru) Антагонисты tweak и рецептора tweak и их использование для лечения иммунологических заболеваний
ES2123810T3 (es) Heterociclos utiles como antagonistas de neuroquinina.
EA199800559A1 (ru) Антагонисты гонадотропин-высвобождающего фактора
EA199800564A1 (ru) Антагонисты гонадотропин-высвобождающего фактора
ES2130265T3 (es) Region de union al receptor de la toxina difterica.
CY1110878T1 (el) Διαδικασιες για την μετρηση της ισχυος του glatiramer acetate
UY27595A1 (es) Compuestos de succinimida heterocíclicos, fusionados y analógos de los mismos, moduladores de la función del receptor de la hormona nuclear
DE59807369D1 (de) Medizinische Bandage
DE69226197T2 (de) Hämoglobine als arzneimittelabgabesystem
BG66085B1 (bg) Фенилаланинови производни
EA200101046A1 (ru) Производные индигоидных бис-индолов
EP0959896A4 (en) COMPOSITIONS BASED ON THE HUMAN THYROTROPIN RECEPTOR AND THEIR USE
DK0973544T3 (da) Immuntolerant prothrombinkomplekspræparat
SE9901077D0 (sv) Novel use
EA200400399A1 (ru) Способы лечения легочных заболеваний
EA200100540A1 (ru) Фармацевтическая композиция с модифицированным высвобождением сенсибилизатора к инсулину
EA200300427A1 (ru) Противоопухолевая терапия, включающая производные дистамицина
ATE416174T1 (de) Substituierte homopiperidylbenzimidazolanaloga als fundusrelaxantien
ES2038064B1 (es) Instalacion portatil de vacunacion aviar.
DE60014429D1 (de) Zusammensetzungen von adenosin a1 agonisten und 5ht3 agonisten