OA12731A - Controlled release polymeric compositions of bone growth promoting compounds. - Google Patents

Controlled release polymeric compositions of bone growth promoting compounds. Download PDF

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Publication number
OA12731A
OA12731A OA1200400150A OA1200400150A OA12731A OA 12731 A OA12731 A OA 12731A OA 1200400150 A OA1200400150 A OA 1200400150A OA 1200400150 A OA1200400150 A OA 1200400150A OA 12731 A OA12731 A OA 12731A
Authority
OA
OAPI
Prior art keywords
composition
compound
polymer
amino
phenoxy
Prior art date
Application number
OA1200400150A
Other languages
English (en)
Inventor
Francis Dumont
Richard Lee Dunn
Scott Alexander Jeffers
Richard Wilker Korsmeyer
Mei Li
Mingxing Zhou
Vishwas Madhav Paralkar
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of OA12731A publication Critical patent/OA12731A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
OA1200400150A 2001-11-30 2002-11-20 Controlled release polymeric compositions of bone growth promoting compounds. OA12731A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33725501P 2001-11-30 2001-11-30

Publications (1)

Publication Number Publication Date
OA12731A true OA12731A (en) 2006-06-28

Family

ID=23319774

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200400150A OA12731A (en) 2001-11-30 2002-11-20 Controlled release polymeric compositions of bone growth promoting compounds.

Country Status (34)

Country Link
US (2) US20030104031A1 (pt)
EP (1) EP1448166A1 (pt)
JP (1) JP4903985B2 (pt)
KR (1) KR100629380B1 (pt)
CN (1) CN1599598A (pt)
AP (1) AP1781A (pt)
AR (1) AR037462A1 (pt)
AU (2) AU2002347502A1 (pt)
BR (1) BR0214610A (pt)
CA (1) CA2468703C (pt)
DO (1) DOP2002000534A (pt)
EA (1) EA011350B1 (pt)
EC (1) ECSP045124A (pt)
GE (1) GEP20063951B (pt)
GT (1) GT200200242A (pt)
HR (1) HRP20040486A2 (pt)
HU (1) HUP0402135A3 (pt)
IL (1) IL161835A0 (pt)
IS (1) IS7217A (pt)
MA (1) MA27084A1 (pt)
MX (1) MXPA04003723A (pt)
NO (1) NO20042273L (pt)
NZ (1) NZ533115A (pt)
OA (1) OA12731A (pt)
PA (1) PA8559001A1 (pt)
PE (1) PE20030581A1 (pt)
PL (1) PL370085A1 (pt)
SV (1) SV2004001421A (pt)
TN (1) TNSN04096A1 (pt)
TW (1) TW200300695A (pt)
UA (1) UA76792C2 (pt)
WO (1) WO2003045351A1 (pt)
YU (1) YU35004A (pt)
ZA (1) ZA200402755B (pt)

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US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
US20040260398A1 (en) * 2003-02-10 2004-12-23 Kelman David C. Resorbable devices
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
EP1670486A4 (en) * 2003-10-01 2009-04-01 Optimer Pharmaceuticals Inc TREATMENT OF A CONDITION IN A MAMMALIAN WITH ADMINISTRATION OF AMINO SUGAR AND USES THEREOF
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US8123787B2 (en) 2004-10-28 2012-02-28 Ogilvie James W Method of treating scoliosis using a biological implant
US8641738B1 (en) 2004-10-28 2014-02-04 James W. Ogilvie Method of treating scoliosis using a biological implant
US20080305144A1 (en) * 2005-08-18 2008-12-11 Brown Malcolm Nmi High Strength Devices and Composites
CN100443065C (zh) * 2006-01-26 2008-12-17 上海交通大学 用于颌面骨缺损修复的复合体系植入体单元
US8722783B2 (en) 2006-11-30 2014-05-13 Smith & Nephew, Inc. Fiber reinforced composite material
EP2142353A1 (en) 2007-04-18 2010-01-13 Smith & Nephew PLC Expansion moulding of shape memory polymers
JP5520814B2 (ja) 2007-04-19 2014-06-11 スミス アンド ネフュー インコーポレーテッド マルチモーダル形状記憶ポリマー
US9770534B2 (en) 2007-04-19 2017-09-26 Smith & Nephew, Inc. Graft fixation
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
EP2172189A1 (en) * 2008-10-01 2010-04-07 Novartis AG Pharmaceutical Compositions
EP2323623B1 (en) 2008-08-12 2016-07-27 Novartis AG Pharmaceutical compositions
US20100130959A1 (en) * 2008-10-15 2010-05-27 Palmetto Biomedical, Inc. Device and method for delivery of therapeutic agents via artificial internal implants
US9642658B2 (en) 2008-10-15 2017-05-09 Orthoclip Llc Device and method for delivery of therapeutic agents via internal implants
US8827884B2 (en) 2009-08-06 2014-09-09 Koninklijke Philips N.V. Oncology therapies employing radioactive seeds
AU2013201121A1 (en) 2011-09-20 2013-04-04 Vical Incorporated Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
CN104189954B (zh) * 2014-09-19 2017-03-29 中国科学院长春应用化学研究所 一种原位固化组织工程支架及其制备方法
RU2571548C1 (ru) * 2014-12-17 2015-12-20 Федеральное государственное бюджетное учреждение науки Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра Российской академии наук Ветеринарное имплантируемое средство пролонгированного действия (варианты)
JP6835841B2 (ja) 2015-11-16 2021-02-24 エボニック オペレーションズ ゲーエムベーハー 非核酸系逆転写酵素阻害剤とポリ(ラクチド−co−グリコリド)とを含む注射液
CN109498852B (zh) * 2018-12-29 2022-06-24 广州噢斯荣医药技术有限公司 治疗骨科疾病的生物降解材料及其应用
EP4054591A1 (en) 2019-11-04 2022-09-14 Astrazeneca AB Combination therapy for treating cancer
JP2024501783A (ja) 2020-12-29 2024-01-15 シノ メディカル サイエンシズ テクノロジー インコーポレイテッド 薬剤溶出ステント
WO2024089417A1 (en) 2022-10-24 2024-05-02 Memorial Sloan-Kettering Cancer Center Tumour stratification for responsiveness to an immune checkpoint inhibitor
WO2024089418A1 (en) 2022-10-24 2024-05-02 Cancer Research Technology Limited Tumour sensitisation to checkpoint inhibitors with redox status modifier

Family Cites Families (7)

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AU1999995A (en) * 1994-04-08 1995-11-10 Atrix Laboratories, Inc. An adjunctive polymer system for use with medical device
WO1996021427A1 (en) 1995-01-09 1996-07-18 Atrix Laboratories, Inc. Liquid polymer delivery system
ATE203157T1 (de) * 1996-12-20 2001-08-15 Alza Corp Injizierbare depotgelzubereitung und herstellungsverfahren
UA59384C2 (uk) * 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
US7128927B1 (en) * 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst

Also Published As

Publication number Publication date
AP1781A (en) 2007-09-27
ECSP045124A (es) 2004-07-23
SV2004001421A (es) 2004-05-07
TW200300695A (en) 2003-06-16
TNSN04096A1 (fr) 2006-06-01
KR100629380B1 (ko) 2006-09-29
MXPA04003723A (es) 2005-04-08
IS7217A (is) 2004-04-07
NO20042273L (no) 2004-07-14
ZA200402755B (en) 2005-04-08
UA76792C2 (uk) 2006-09-15
GEP20063951B (en) 2006-10-25
KR20040062977A (ko) 2004-07-09
US20090169595A1 (en) 2009-07-02
PA8559001A1 (es) 2003-11-12
JP4903985B2 (ja) 2012-03-28
CA2468703A1 (en) 2003-06-05
AU2009200125B2 (en) 2012-02-02
AU2002347502A1 (en) 2003-06-10
AU2009200125A1 (en) 2009-02-05
HUP0402135A3 (en) 2008-04-28
US8017144B2 (en) 2011-09-13
IL161835A0 (en) 2005-11-20
GT200200242A (es) 2003-06-25
HRP20040486A2 (en) 2004-10-31
EP1448166A1 (en) 2004-08-25
CA2468703C (en) 2009-12-29
WO2003045351A1 (en) 2003-06-05
MA27084A1 (fr) 2004-12-20
YU35004A (sh) 2006-08-17
DOP2002000534A (es) 2003-05-31
AR037462A1 (es) 2004-11-10
JP2005515190A (ja) 2005-05-26
EA200400608A1 (ru) 2004-10-28
US20030104031A1 (en) 2003-06-05
BR0214610A (pt) 2004-09-14
PE20030581A1 (es) 2003-07-08
AP2004003037A0 (en) 2004-06-30
NZ533115A (en) 2005-12-23
EA011350B1 (ru) 2009-02-27
HUP0402135A2 (hu) 2005-02-28
PL370085A1 (en) 2005-05-16
CN1599598A (zh) 2005-03-23

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