MA27084A1 - Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse. - Google Patents

Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse.

Info

Publication number
MA27084A1
MA27084A1 MA27688A MA27688A MA27084A1 MA 27084 A1 MA27084 A1 MA 27084A1 MA 27688 A MA27688 A MA 27688A MA 27688 A MA27688 A MA 27688A MA 27084 A1 MA27084 A1 MA 27084A1
Authority
MA
Morocco
Prior art keywords
bone growth
controlled release
fluid composition
polymer compositions
compound
Prior art date
Application number
MA27688A
Other languages
English (en)
Inventor
Francis Dumont
Mei Li
Richard Lee Dunn
Mingxing Zhou
Richard Wilker Korsmeyer
Vishwas Madhav Paralkar
Scott Alexander Jeffers
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA27084A1 publication Critical patent/MA27084A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

DEPOSANT Société dite: PFIZER INC. REVENDICATION DE PRIORITES US 30 Novembre 2001 60/337,255 Voir en annexe le titre de l'invention et le texte de l'abrégé Compositions polymères à libération contrôlée, comprenant des composés favorisant la croissance osseuse La présente invention concerne un système perfectionné pour la libération contrôlée d'un composé favorisant la croissance osseuse, et une composition fluide pour sa formation. La composition fluide est constituée d'un composé favorisant la croissance osseuse, d'un polymère thermoplastique et d'un solvant organique. La composition fluide est capable de former une matrice polymère solide microporeuse biodégradable et/ou bioérodable. La matrice est utile comme implant chez des patients (homme et animaux) pour délivrer un composé favorisant la croissance osseuse à certains tissus.
MA27688A 2001-11-30 2004-05-20 Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse. MA27084A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33725501P 2001-11-30 2001-11-30

Publications (1)

Publication Number Publication Date
MA27084A1 true MA27084A1 (fr) 2004-12-20

Family

ID=23319774

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27688A MA27084A1 (fr) 2001-11-30 2004-05-20 Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse.

Country Status (34)

Country Link
US (2) US20030104031A1 (fr)
EP (1) EP1448166A1 (fr)
JP (1) JP4903985B2 (fr)
KR (1) KR100629380B1 (fr)
CN (1) CN1599598A (fr)
AP (1) AP1781A (fr)
AR (1) AR037462A1 (fr)
AU (2) AU2002347502A1 (fr)
BR (1) BR0214610A (fr)
CA (1) CA2468703C (fr)
DO (1) DOP2002000534A (fr)
EA (1) EA011350B1 (fr)
EC (1) ECSP045124A (fr)
GE (1) GEP20063951B (fr)
GT (1) GT200200242A (fr)
HR (1) HRP20040486A2 (fr)
HU (1) HUP0402135A3 (fr)
IL (1) IL161835A0 (fr)
IS (1) IS7217A (fr)
MA (1) MA27084A1 (fr)
MX (1) MXPA04003723A (fr)
NO (1) NO20042273L (fr)
NZ (1) NZ533115A (fr)
OA (1) OA12731A (fr)
PA (1) PA8559001A1 (fr)
PE (1) PE20030581A1 (fr)
PL (1) PL370085A1 (fr)
SV (1) SV2004001421A (fr)
TN (1) TNSN04096A1 (fr)
TW (1) TW200300695A (fr)
UA (1) UA76792C2 (fr)
WO (1) WO2003045351A1 (fr)
YU (1) YU35004A (fr)
ZA (1) ZA200402755B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
WO2004071356A2 (fr) * 2003-02-10 2004-08-26 Smith & Nephew, Inc. Dispositifs resorbables
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
CA2540586A1 (fr) * 2003-10-01 2005-04-21 Optimer Pharmaceuticals, Inc. Traitement d'un trouble chez un mammifere par administration d'une sucre amine et utilisations associees
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US8123787B2 (en) 2004-10-28 2012-02-28 Ogilvie James W Method of treating scoliosis using a biological implant
US8641738B1 (en) 2004-10-28 2014-02-04 James W. Ogilvie Method of treating scoliosis using a biological implant
US20080305144A1 (en) * 2005-08-18 2008-12-11 Brown Malcolm Nmi High Strength Devices and Composites
CN100443065C (zh) * 2006-01-26 2008-12-17 上海交通大学 用于颌面骨缺损修复的复合体系植入体单元
AU2007325001B2 (en) 2006-11-30 2014-04-10 Smith & Nephew, Inc. Fiber reinforced composite material
AU2008240418B2 (en) 2007-04-18 2013-08-15 Smith & Nephew Plc Expansion moulding of shape memory polymers
JP5680957B2 (ja) 2007-04-19 2015-03-04 スミス アンド ネフュー インコーポレーテッドＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ，Ｉｎｃ． グラフト固定
ATE547129T1 (de) 2007-04-19 2012-03-15 Smith & Nephew Inc Multimodale formgedächtnis-polymere
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
EP2172189A1 (fr) * 2008-10-01 2010-04-07 Novartis AG Compositions pharmaceutiques
WO2010018159A1 (fr) 2008-08-12 2010-02-18 Novartis Ag Compositions pharmaceutiques
US9642658B2 (en) 2008-10-15 2017-05-09 Orthoclip Llc Device and method for delivery of therapeutic agents via internal implants
EP2346421A1 (fr) * 2008-10-15 2011-07-27 Bioshape Solutions Inc. Dispositif et procédé destinés à fournir des agents thérapeutiques par le biais d'implants internes
BR112012002341A8 (pt) 2009-08-06 2017-10-10 Koninklijke Philips Electronics Nv Semente radioativa para uso na terapia oncológica e método de terapia oncológica
US20130071403A1 (en) 2011-09-20 2013-03-21 Vical Incorporated Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
CN104189954B (zh) * 2014-09-19 2017-03-29 中国科学院长春应用化学研究所 一种原位固化组织工程支架及其制备方法
RU2571548C1 (ru) * 2014-12-17 2015-12-20 Федеральное государственное бюджетное учреждение науки Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра Российской академии наук Ветеринарное имплантируемое средство пролонгированного действия (варианты)
CN108289844B (zh) 2015-11-16 2021-09-14 赢创运营有限公司 包含非核苷逆转录酶抑制剂和聚(丙交酯-共-乙交酯)的注射溶液
CN109498852B (zh) * 2018-12-29 2022-06-24 广州噢斯荣医药技术有限公司 治疗骨科疾病的生物降解材料及其应用
WO2021090146A1 (fr) 2019-11-04 2021-05-14 Astrazeneca Ab Polythérapie pour le traitement du cancer
KR20230150790A (ko) 2020-12-29 2023-10-31 시노 메디칼 사이언시즈 테크놀로지, 인코포레이티드 약물 용출 스텐트
WO2024089417A1 (fr) 2022-10-24 2024-05-02 Memorial Sloan-Kettering Cancer Center Stratification de tumeurs pour déterminer la sensibilité à un inhibiteur de point de contrôle immunitaire
WO2024089418A1 (fr) 2022-10-24 2024-05-02 Cancer Research Technology Limited Sensibilisation tumorale à des inhibiteurs de points de contrôle avec modificateur d'état redox

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0754064B1 (fr) * 1994-04-08 2003-05-28 Atrix Laboratories, Inc. Systeme auxiliaire de polymeres pour dispositif medical
AU4652596A (en) 1995-01-09 1996-07-31 Atrix Laboratories, Inc. Liquid polymer delivery system
CA2275587C (fr) * 1996-12-20 2006-10-24 Alza Corporation Composition de gel injectable a effet retard et son procede de preparation
UA59384C2 (uk) * 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
US7128927B1 (en) * 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst

Also Published As

Publication number Publication date
GT200200242A (es) 2003-06-25
HUP0402135A2 (hu) 2005-02-28
JP2005515190A (ja) 2005-05-26
PL370085A1 (en) 2005-05-16
CN1599598A (zh) 2005-03-23
AU2002347502A1 (en) 2003-06-10
CA2468703A1 (fr) 2003-06-05
TNSN04096A1 (fr) 2006-06-01
MXPA04003723A (es) 2005-04-08
ZA200402755B (en) 2005-04-08
HUP0402135A3 (en) 2008-04-28
KR20040062977A (ko) 2004-07-09
AU2009200125B2 (en) 2012-02-02
EP1448166A1 (fr) 2004-08-25
WO2003045351A1 (fr) 2003-06-05
GEP20063951B (en) 2006-10-25
YU35004A (sh) 2006-08-17
NO20042273L (no) 2004-07-14
DOP2002000534A (es) 2003-05-31
JP4903985B2 (ja) 2012-03-28
EA011350B1 (ru) 2009-02-27
KR100629380B1 (ko) 2006-09-29
BR0214610A (pt) 2004-09-14
ECSP045124A (es) 2004-07-23
AR037462A1 (es) 2004-11-10
PA8559001A1 (es) 2003-11-12
AP2004003037A0 (en) 2004-06-30
UA76792C2 (uk) 2006-09-15
IS7217A (is) 2004-04-07
EA200400608A1 (ru) 2004-10-28
AP1781A (en) 2007-09-27
NZ533115A (en) 2005-12-23
IL161835A0 (en) 2005-11-20
TW200300695A (en) 2003-06-16
US20090169595A1 (en) 2009-07-02
PE20030581A1 (es) 2003-07-08
CA2468703C (fr) 2009-12-29
US20030104031A1 (en) 2003-06-05
OA12731A (en) 2006-06-28
SV2004001421A (es) 2004-05-07
AU2009200125A1 (en) 2009-02-05
HRP20040486A2 (en) 2004-10-31
US8017144B2 (en) 2011-09-13

Similar Documents

Publication Publication Date Title
MA27084A1 (fr) Compositions polymeres a liberation controlee, comprenant des composes favorisant la croissance osseuse.
JP4644252B2 (ja) インサイチュー硬化ペースト、その製造および使用
EP2269663B1 (fr) Greffe osseuse et biocomposite
WO2001091725A3 (fr) Polyphosphates presentant une utilite biologique
IL142470A0 (en) Controlled release liquid delivery compositions with low initial drug burst
CA2268156A1 (fr) Compositions bioceramiques
EP3238665A3 (fr) Implant médical durci par chromisation
CY1109272T1 (el) Συνθεση παρατεταμενης απελευθερωσεως περιλαμβανουσα συμπολυμερες γαλακτικου οξεος-γλυκολικου οξεος και μεθοδος παρασκευης της
WO2002053105A3 (fr) Compositions et procedes destines a des applications biomedicales
BR9811000A (pt) "composições poliméricas"
CN102368999A (zh) 抗坏血酸磷酸酯缓释体系
WO2006096720A1 (fr) Vis pour implant dentaire et procede d'utilisation
HK1082728A1 (en) Azabicyclo derivatives as muscarinic receptor antagonists
WO2006118461A3 (fr) Matieres supramoleculaires biologiquement actives modulaires, bioresorbables ou biomedicales
EP0937468A3 (fr) Composition adhésive à usage chirurgical
ATE555798T1 (de) Gewebeimplantate und verfahren zur ihrer herstellung und verwendung
WO2005007802A3 (fr) Composite fibreux pour genie tissulaire
WO2004067044A3 (fr) Composite adhesif actionne par la lumiere, systeme et procedes associes
WO2001068052A3 (fr) Polymeres biodegradables a base de phosphate
WO2002040069A3 (fr) Suture chirurgicale bioactive
ATE486583T1 (de) Pharmazeutische zusammensetzung enthaltend anastrozol
DE50012797D1 (de) Strangförmiges Implantat aus resorbierbarem Polymermaterial, Verfahren zu seiner Herstellung
CA2368348A1 (fr) Composition oligomere-polymere injectable biodegradable
DE50208851D1 (de) Gelierzucker und verfahren zu dessen herstellung
WO2007023281A3 (fr) Composes biologiquement actifs