ATE555798T1 - Gewebeimplantate und verfahren zur ihrer herstellung und verwendung - Google Patents

Gewebeimplantate und verfahren zur ihrer herstellung und verwendung

Info

Publication number
ATE555798T1
ATE555798T1 AT02761332T AT02761332T ATE555798T1 AT E555798 T1 ATE555798 T1 AT E555798T1 AT 02761332 T AT02761332 T AT 02761332T AT 02761332 T AT02761332 T AT 02761332T AT E555798 T1 ATE555798 T1 AT E555798T1
Authority
AT
Austria
Prior art keywords
tissue
matrices
production
methods
tissue implants
Prior art date
Application number
AT02761332T
Other languages
English (en)
Inventor
Giuseppe Intini
Sebastiano Andreana
Libuse Anna Bobek
Rosemary Dziak
Original Assignee
Giuseppe Intini
Sebastiano Andreana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuseppe Intini, Sebastiano Andreana filed Critical Giuseppe Intini
Application granted granted Critical
Publication of ATE555798T1 publication Critical patent/ATE555798T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/10Ceramics or glasses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Ceramic Engineering (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT02761332T 2001-08-09 2002-08-09 Gewebeimplantate und verfahren zur ihrer herstellung und verwendung ATE555798T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31121601P 2001-08-09 2001-08-09
PCT/US2002/025549 WO2003015800A1 (en) 2001-08-09 2002-08-09 Tissue implants and methods for making and using same

Publications (1)

Publication Number Publication Date
ATE555798T1 true ATE555798T1 (de) 2012-05-15

Family

ID=23205916

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02761332T ATE555798T1 (de) 2001-08-09 2002-08-09 Gewebeimplantate und verfahren zur ihrer herstellung und verwendung

Country Status (7)

Country Link
US (2) US8257737B2 (de)
EP (1) EP1416943B1 (de)
JP (1) JP2005500881A (de)
AT (1) ATE555798T1 (de)
CA (1) CA2456716A1 (de)
ES (1) ES2386280T3 (de)
WO (1) WO2003015800A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257737B2 (en) 2001-08-09 2012-09-04 Giuseppe Intini Tissue implants and methods for making and using same
US7608258B2 (en) 2002-04-13 2009-10-27 Allan Mishra Method for treatment of tendinosis using platelet rich plasma
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20050008629A1 (en) * 2002-05-08 2005-01-13 Interpore Orthopaedics, A Delaware Corporation Encapsulated AGF cells
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20070122906A1 (en) * 2003-12-29 2007-05-31 Allan Mishra Method of culturing cells
US7678780B2 (en) 2003-12-29 2010-03-16 Allan Mishra Method of treating cancer using platelet releasate
US7462268B2 (en) 2004-08-20 2008-12-09 Allan Mishra Particle/cell separation device and compositions
US20070258956A1 (en) * 2006-05-02 2007-11-08 Biomet Manufacturing Corp. Methods and apparatus for promoting hair growth using adipose cell based therapies
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
TW200808388A (en) * 2006-08-04 2008-02-16 Ye Nan Hui Manufacturing method for biomedical filler containing thrombospondin and growth factor
EP2462895B1 (de) * 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Zusammensetzungen und Verfahren für Behandlungen von Arthodese
US7806276B2 (en) 2007-04-12 2010-10-05 Hanuman, Llc Buoy suspension fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
EP2259774B1 (de) 2008-02-27 2012-12-12 Biomet Biologics, LLC Verfahren und zusammensetzungen zur abgabe eines interleukin-1-rezeptor-antagonisten
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US20100112081A1 (en) 2008-10-07 2010-05-06 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
CN116688233A (zh) * 2022-02-25 2023-09-05 上海软馨生物科技有限公司 一种组织工程软骨颗粒移植物及其制备方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034352A (en) * 1985-06-25 1991-07-23 Lifecore Biomedical, Inc. Calcium phosphate materials
US4980286A (en) * 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
EP0228458B2 (de) 1985-07-05 1997-10-22 Whitehead Institute For Biomedical Research Expression von fremdem genetischem material in epithelzellen
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US6150328A (en) * 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
WO1989005345A1 (en) 1987-12-11 1989-06-15 Whitehead Institute For Biomedical Research Genetic modification of endothelial cells
DE68927996T2 (de) 1988-02-05 1997-12-04 Hughes Howard Med Inst Modifizierte hepatozyten und deren anwendung
US5147403A (en) * 1989-03-15 1992-09-15 United States Gypsum Company Prosthesis implantation method
DE69034078T2 (de) 1989-03-21 2004-04-01 Vical, Inc., San Diego Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
CN1052695A (zh) 1989-12-22 1991-07-03 中国科学院生物物理研究所 一种转移基因的方法及其转移基因的粒子枪
US5425769A (en) * 1990-04-23 1995-06-20 Snyders, Jr.; Robert V. Composition of material for osseous repair
US5462722A (en) * 1991-04-17 1995-10-31 Liu; Sung-Tsuen Calcium phosphate calcium sulfate composite implant material
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
AU2297395A (en) * 1994-04-20 1995-11-16 Institute Of Molecular Biology, Inc. Administration of platelet-derived growth factor and bone seeking drugs for osteoporosis and bone regeneration
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US5817327A (en) * 1994-07-27 1998-10-06 The Trustees Of The University Of Pennsylvania Incorporation of biologically active molecules into bioactive glasses
US5733545A (en) 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
US6361933B1 (en) * 1996-06-14 2002-03-26 Biostore New Zealand Limited Solutions for the preservation of tissues
US6037116A (en) * 1996-06-14 2000-03-14 Biostore New Zealand, Ltd. Compositions comprising betaine, sodium citrate and sodium chloride and methods for the preservation of biological materials
EP0944312B9 (de) * 1996-12-13 2006-07-05 ZymoGenetics, Inc. Zusammensetzungen und verfahren zum stimulieren von knochenwachstum
US6080779A (en) * 1996-12-13 2000-06-27 Osteoscreen, Inc. Compositions and methods for stimulating bone growth
US6179872B1 (en) * 1998-03-17 2001-01-30 Tissue Engineering Biopolymer matt for use in tissue repair and reconstruction
AR022333A1 (es) * 1999-01-26 2002-09-04 Anitua Aldecoa Eduardo Regenerador de tejido oseo
DE19960490A1 (de) * 1999-12-15 2001-07-12 Curasan Ag Regenerationsmittel
US20030103960A1 (en) * 1999-12-22 2003-06-05 Pierre Philippart Sealant and bone generating product
US7030127B2 (en) * 2001-06-29 2006-04-18 Ethicon, Inc. Composition and medical devices utilizing bioabsorbable polymeric waxes
US8257737B2 (en) 2001-08-09 2012-09-04 Giuseppe Intini Tissue implants and methods for making and using same

Also Published As

Publication number Publication date
US20090098204A1 (en) 2009-04-16
US8257737B2 (en) 2012-09-04
EP1416943A1 (de) 2004-05-12
ES2386280T3 (es) 2012-08-16
EP1416943B1 (de) 2012-05-02
EP1416943A4 (de) 2008-02-13
US20030143211A1 (en) 2003-07-31
CA2456716A1 (en) 2003-02-27
WO2003015800A1 (en) 2003-02-27
JP2005500881A (ja) 2005-01-13

Similar Documents

Publication Publication Date Title
ATE555798T1 (de) Gewebeimplantate und verfahren zur ihrer herstellung und verwendung
DE602004027188D1 (de) Verfahren zur Herstellung bioabsorbierbarer, poröser und verstärkter Gewebeimplantate und dadurch hergestellte Implantate
ATE493492T1 (de) Verfahren und system zur herstellung von stammzellen aus fettgewebe
DE60141964D1 (de) Bandscheibe
ATE547134T1 (de) Dentalimplantat und verfahren zu dessen herstellung
DE50002122D1 (de) Resorbierbares knochen-implantatmaterial sowie verfahren zur herstellung desselben
ATE458506T1 (de) Knochenmarkersatzmaterial-verbundwerkstoff, verfahren zu seiner herstelllung und kit
DE60214477D1 (de) Implantat zur Regeneration von Knorpelgewebe
DE112007003309A5 (de) Knochenimplantat sowie Set zur Herstellung von Knochenimplantaten
ATE487504T1 (de) Zusammensetzungen und verfahren für biomedizinische anwendungen
DE502004002651D1 (de) Verankerungselement zur Verwendung in der Wirbelsäulen- oder Knochenchirurgie und Verfahren zu seiner Herstellung
WO2006047310A3 (en) Hollow and porous orthopaedic or dental implant that delivers a biological agent
DE60128723D1 (de) Verfahren zur herstellung von bio-resorbierbaren implantaten
ATE464073T1 (de) Metallimplantate mit einer aufgerauhten oberfläche und verfahren zu ihrer herstellung
IL174266A0 (en) Artificial spinal discs implantation instruments and methods
WO2004041075A3 (en) A semi-biological intervertebral disc replacement system
ATE296123T1 (de) Verfahren zur herstellung bioaktiver implantatoberflächen
AU2003279231A1 (en) Bone and tissue implants and method of making
WO2005016388A3 (en) Structural/biological implant system
DE10196235T1 (de) Verwendung von Kollagen aquatischen Ursprungs zur Herstellung von Trägern für die Gewebebildung sowie diese Träger und Biomaterialien
EP3238665A3 (de) Diffusionsgehärtetes medizinisches implantat
EP1449500A3 (de) Modulares Knochenimplantat, Werkzeug und Verfahren
HK1068640A1 (en) Time release calcium sulfate matrix for bone augmentation
SG152297A1 (en) Composition for stimulating bone growth and differentiation and method for isolating same
DE60135019D1 (de) Elektroverarbeitetes kollagen