YU35004A - Polimerni preparati sa kontrolisanim oslobađanjem jedinjenja koja pomažu rast kosti - Google Patents

Polimerni preparati sa kontrolisanim oslobađanjem jedinjenja koja pomažu rast kosti

Info

Publication number
YU35004A
YU35004A YU35004A YUP35004A YU35004A YU 35004 A YU35004 A YU 35004A YU 35004 A YU35004 A YU 35004A YU P35004 A YUP35004 A YU P35004A YU 35004 A YU35004 A YU 35004A
Authority
YU
Yugoslavia
Prior art keywords
bone growth
growth promoting
controlled release
polymeric compositions
release polymeric
Prior art date
Application number
YU35004A
Other languages
English (en)
Inventor
Francis Dumont
Richard Wilke Korsmeyer
Mei Li
Vishwas Madhav Paralkar
Richard Lee Dunn
Scott Alexander Jeffers
Mingxing Zhou
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU35004A publication Critical patent/YU35004A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

Ovaj pronalazak je usmeren na poboljšani sistem za kontrolisano oslobađanje jedinjenja koja pomažu rast kosti i na tečljivi preparat za njegovo formiranje. Ovaj tečljivi preparat je sačinjen od jedinjenja koje pomaže rast kosti, termoplastičnog polimera i organskog rastvarača. Ovaj tečljivi preparat je u stanju da formira biodegradabilnu i/ili bioerozivnu mikroporoznu čvrstu polimernu matricu. Ova matrica je korisna kao implantat u pacijentima (humanim i animalnim) za oslobađanje jedinjenja koje pomaže rast kosti u nekim tkivima.[The present invention is directed to an improved system for controlled release of a bone growth promoting compound and to a flowable composition for its formation. The flowable composition is composed of a bone growth promoting compound, a thermoplastic polymer and an organic solvent. The flowable composition is capable of forming a biodegradable and/or bioerodible microporous, solid polymer matrix. The matrix is useful as an implant in patients (humans and animals) for delivery of a bone growth promoting compound to certain tissues.
YU35004A 2001-11-30 2002-11-20 Polimerni preparati sa kontrolisanim oslobađanjem jedinjenja koja pomažu rast kosti YU35004A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33725501P 2001-11-30 2001-11-30

Publications (1)

Publication Number Publication Date
YU35004A true YU35004A (sh) 2006-08-17

Family

ID=23319774

Family Applications (1)

Application Number Title Priority Date Filing Date
YU35004A YU35004A (sh) 2001-11-30 2002-11-20 Polimerni preparati sa kontrolisanim oslobađanjem jedinjenja koja pomažu rast kosti

Country Status (34)

Country Link
US (2) US20030104031A1 (sh)
EP (1) EP1448166A1 (sh)
JP (1) JP4903985B2 (sh)
KR (1) KR100629380B1 (sh)
CN (1) CN1599598A (sh)
AP (1) AP1781A (sh)
AR (1) AR037462A1 (sh)
AU (2) AU2002347502A1 (sh)
BR (1) BR0214610A (sh)
CA (1) CA2468703C (sh)
DO (1) DOP2002000534A (sh)
EA (1) EA011350B1 (sh)
EC (1) ECSP045124A (sh)
GE (1) GEP20063951B (sh)
GT (1) GT200200242A (sh)
HR (1) HRP20040486A2 (sh)
HU (1) HUP0402135A3 (sh)
IL (1) IL161835A0 (sh)
IS (1) IS7217A (sh)
MA (1) MA27084A1 (sh)
MX (1) MXPA04003723A (sh)
NO (1) NO20042273L (sh)
NZ (1) NZ533115A (sh)
OA (1) OA12731A (sh)
PA (1) PA8559001A1 (sh)
PE (1) PE20030581A1 (sh)
PL (1) PL370085A1 (sh)
SV (1) SV2004001421A (sh)
TN (1) TNSN04096A1 (sh)
TW (1) TW200300695A (sh)
UA (1) UA76792C2 (sh)
WO (1) WO2003045351A1 (sh)
YU (1) YU35004A (sh)
ZA (1) ZA200402755B (sh)

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US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
EP1596765A2 (en) * 2003-02-10 2005-11-23 Smith & Nephew, Inc. Resorbable devices
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
JP2007507516A (ja) * 2003-10-01 2007-03-29 オプティマー・ファーマスーティカルズ・インコーポレイテッド アミノ糖投与による哺乳動物の障害の治療及びアミノ糖の使用
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US8641738B1 (en) 2004-10-28 2014-02-04 James W. Ogilvie Method of treating scoliosis using a biological implant
US8123787B2 (en) 2004-10-28 2012-02-28 Ogilvie James W Method of treating scoliosis using a biological implant
CA2619571A1 (en) * 2005-08-18 2007-02-22 Smith & Nephew, Plc High strength devices and composites
CN100443065C (zh) * 2006-01-26 2008-12-17 上海交通大学 用于颌面骨缺损修复的复合体系植入体单元
CA2679365C (en) 2006-11-30 2016-05-03 Smith & Nephew, Inc. Fiber reinforced composite material
JP5416090B2 (ja) 2007-04-18 2014-02-12 スミス アンド ネフュー ピーエルシー 形状記憶ポリマーの膨張成形
EP2142227B1 (en) 2007-04-19 2012-02-29 Smith & Nephew, Inc. Multi-modal shape memory polymers
EP2150288B1 (en) 2007-04-19 2011-04-13 Smith & Nephew, Inc. Graft fixation
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20090181068A1 (en) * 2008-01-14 2009-07-16 Dunn Richard L Low Viscosity Liquid Polymeric Delivery System
CN102119022B (zh) 2008-08-12 2015-09-09 诺华股份有限公司 药物组合物
EP2172189A1 (en) * 2008-10-01 2010-04-07 Novartis AG Pharmaceutical Compositions
WO2010045487A1 (en) * 2008-10-15 2010-04-22 Palmetto Biomedical, Inc. Device and method for delivery of therapeutic agents via internal implants
US9642658B2 (en) 2008-10-15 2017-05-09 Orthoclip Llc Device and method for delivery of therapeutic agents via internal implants
EP2464389A2 (en) 2009-08-06 2012-06-20 Koninklijke Philips Electronics N.V. Oncology therapies employing radioactive seeds
US20130071403A1 (en) 2011-09-20 2013-03-21 Vical Incorporated Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
CN104189954B (zh) * 2014-09-19 2017-03-29 中国科学院长春应用化学研究所 一种原位固化组织工程支架及其制备方法
RU2571548C1 (ru) * 2014-12-17 2015-12-20 Федеральное государственное бюджетное учреждение науки Институт органической и физической химии им. А.Е. Арбузова Казанского научного центра Российской академии наук Ветеринарное имплантируемое средство пролонгированного действия (варианты)
SG11201804037XA (en) 2015-11-16 2018-06-28 Evonik Roehm Gmbh Injection solution comprising a non-nucleoside reverse-transcriptase inhibitor and poly(lactide-co-glycolide)
CN109498852B (zh) * 2018-12-29 2022-06-24 广州噢斯荣医药技术有限公司 治疗骨科疾病的生物降解材料及其应用
CN114599372A (zh) 2019-11-04 2022-06-07 阿斯利康(瑞典)有限公司 用于治疗癌症的组合疗法
EP4255357A1 (en) 2020-12-29 2023-10-11 Sino Medical Sciences Technology Inc. Drug eluting stent
WO2024089418A1 (en) 2022-10-24 2024-05-02 Cancer Research Technology Limited Tumour sensitisation to checkpoint inhibitors with redox status modifier
WO2024089417A1 (en) 2022-10-24 2024-05-02 Memorial Sloan-Kettering Cancer Center Tumour stratification for responsiveness to an immune checkpoint inhibitor
WO2024150017A1 (en) 2023-01-13 2024-07-18 Akrivia Biomedics Limited Method of profiling diseases

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UA59384C2 (uk) * 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
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Also Published As

Publication number Publication date
HUP0402135A2 (hu) 2005-02-28
GEP20063951B (en) 2006-10-25
US8017144B2 (en) 2011-09-13
TW200300695A (en) 2003-06-16
AU2009200125A1 (en) 2009-02-05
CA2468703C (en) 2009-12-29
PE20030581A1 (es) 2003-07-08
HUP0402135A3 (en) 2008-04-28
KR20040062977A (ko) 2004-07-09
WO2003045351A1 (en) 2003-06-05
AU2009200125B2 (en) 2012-02-02
MXPA04003723A (es) 2005-04-08
NZ533115A (en) 2005-12-23
ZA200402755B (en) 2005-04-08
CN1599598A (zh) 2005-03-23
TNSN04096A1 (fr) 2006-06-01
AP2004003037A0 (en) 2004-06-30
EA011350B1 (ru) 2009-02-27
UA76792C2 (uk) 2006-09-15
JP2005515190A (ja) 2005-05-26
US20030104031A1 (en) 2003-06-05
DOP2002000534A (es) 2003-05-31
PA8559001A1 (es) 2003-11-12
EA200400608A1 (ru) 2004-10-28
EP1448166A1 (en) 2004-08-25
MA27084A1 (fr) 2004-12-20
ECSP045124A (es) 2004-07-23
AR037462A1 (es) 2004-11-10
IL161835A0 (en) 2005-11-20
OA12731A (en) 2006-06-28
US20090169595A1 (en) 2009-07-02
JP4903985B2 (ja) 2012-03-28
GT200200242A (es) 2003-06-25
AP1781A (en) 2007-09-27
CA2468703A1 (en) 2003-06-05
IS7217A (is) 2004-04-07
AU2002347502A1 (en) 2003-06-10
BR0214610A (pt) 2004-09-14
NO20042273L (no) 2004-07-14
PL370085A1 (en) 2005-05-16
SV2004001421A (es) 2004-05-07
HRP20040486A2 (en) 2004-10-31
KR100629380B1 (ko) 2006-09-29

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