OA12063A - Synergistic combinations of an UK1 receptor antag onist and a GABA structural analog. - Google Patents
Synergistic combinations of an UK1 receptor antag onist and a GABA structural analog. Download PDFInfo
- Publication number
- OA12063A OA12063A OA1200200107A OA1200200107A OA12063A OA 12063 A OA12063 A OA 12063A OA 1200200107 A OA1200200107 A OA 1200200107A OA 1200200107 A OA1200200107 A OA 1200200107A OA 12063 A OA12063 A OA 12063A
- Authority
- OA
- OAPI
- Prior art keywords
- gaba
- receptor antagonist
- composition
- gabapentin
- ethyl
- Prior art date
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A61P31/12—Antivirals
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US15827199P | 1999-10-07 | 1999-10-07 |
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| TR (1) | TR200200913T2 (cs) |
| UY (1) | UY26376A1 (cs) |
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Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| HU228426B1 (hu) | 1996-07-24 | 2013-03-28 | Warner Lambert Co | Izobutil-gaba és származékai alkalmazása fájdalom kezelésére alkalmas gyógyszer elõállítására |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| JP2005523334A (ja) * | 2002-04-24 | 2005-08-04 | サイプレス バイオサイエンス， インコーポレイテッド | ストレス関連障害を含む機能的身体障害の予防および処置 |
| WO2004032905A1 (en) * | 2002-10-08 | 2004-04-22 | Ranbaxy Laboratories Limited | Gabapentin tablets and methods for their preparation |
| WO2004084881A1 (en) * | 2003-03-21 | 2004-10-07 | Dynogen Pharmaceuticals, Inc. | METHODS FOR TREATING FUNCTIONAL BOWEL DISORDERS USING α2δ SUBUNIT CALCIUM CHANNEL MODULATORS WITH SMOOTH MUSCLE MODULATORS |
| EP1492519B1 (en) * | 2003-03-21 | 2006-11-15 | Dynogen Pharmaceuticals, Inc. | Methods for treating lower urinary tract disorders using antimuscarinics and alpha-2-delta subunit calcium channel modulators |
| US20060264509A1 (en) * | 2003-03-21 | 2006-11-23 | Fraser Matthew O | Methods for treating pain using smooth muscle modulators and a2 subunit calcium channel modulators |
| EP1543831A1 (en) * | 2003-12-18 | 2005-06-22 | Pfizer GmbH Arzneimittelwerk Gödecke | Pregabalin composition |
| DE102007019071A1 (de) * | 2007-04-23 | 2008-10-30 | Ratiopharm Gmbh | Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin |
| RU2544552C2 (ru) | 2010-07-30 | 2015-03-20 | Торэй Индастриз, Инк. | Терапевтическое средство или профилактическое средство для нейропатической боли |
| CN107050456B (zh) * | 2010-09-28 | 2022-08-12 | 加利福尼亚大学董事会 | 治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合 |
| AU2020249679B2 (en) | 2019-03-26 | 2024-11-21 | Orion Corporation | Pregabalin formulations and use thereof |
| WO2022234110A1 (en) * | 2021-05-07 | 2022-11-10 | Plus Vitech, S.L. | Gamma-aminobutyric acid derivatives for use in cancer therapy |
Family Cites Families (5)
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| US5025035A (en) * | 1990-10-12 | 1991-06-18 | Warner-Lambert Company | Method of treating depression |
| US5792796A (en) * | 1994-07-27 | 1998-08-11 | Warner-Lambert Company | Methods for treating anxiety and panic |
| US5510381A (en) * | 1995-05-15 | 1996-04-23 | Warner-Lambert Company | Method of treatment of mania and bipolar disorder |
| CA2266773A1 (en) * | 1996-10-07 | 1998-04-16 | Merck Sharp & Dohme Limited | Use of a nk-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent |
| JP2001504848A (ja) * | 1996-12-02 | 2001-04-10 | メルク シヤープ エンド ドーム リミテツド | 重症不安障害の治療のためのｎｋ−１受容体拮抗薬の使用 |
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2000
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- 2000-10-05 OA OA1200200107A patent/OA12063A/en unknown
- 2000-10-05 CA CA002385930A patent/CA2385930A1/en not_active Abandoned
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- 2000-10-05 PT PT00966138T patent/PT1221950E/pt unknown
- 2000-10-05 WO PCT/EP2000/009858 patent/WO2001024792A1/en not_active Application Discontinuation
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- 2000-10-05 IL IL14896500A patent/IL148965A0/xx unknown
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- 2000-10-05 HU HU0203466A patent/HUP0203466A3/hu unknown
- 2000-10-05 PL PL00357498A patent/PL357498A1/xx not_active Application Discontinuation
- 2000-10-05 AT AT00966138T patent/ATE269072T1/de not_active IP Right Cessation
- 2000-10-06 CO CO00076105A patent/CO5280195A1/es not_active Application Discontinuation
- 2000-10-06 UY UY26376A patent/UY26376A1/es not_active Application Discontinuation
- 2000-10-06 PA PA20008504301A patent/PA8504301A1/es unknown
- 2000-10-06 PE PE2000001069A patent/PE20010708A1/es not_active Application Discontinuation
- 2000-10-06 GT GT200000166A patent/GT200000166A/es unknown
- 2000-10-06 AR ARP000105296A patent/AR029646A1/es not_active Application Discontinuation
- 2000-10-09 EP EP00979495A patent/EP1233766A1/en not_active Withdrawn
- 2000-10-09 AU AU16962/01A patent/AU1696201A/en not_active Abandoned
- 2000-10-09 WO PCT/EP2000/010084 patent/WO2001024791A1/en not_active Application Discontinuation
- 2000-10-09 JP JP2001527790A patent/JP2003510355A/ja not_active Withdrawn
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2002
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- 2002-04-05 NO NO20021625A patent/NO20021625L/no not_active Application Discontinuation
- 2002-04-05 CR CR6614A patent/CR6614A/es not_active Application Discontinuation
- 2002-04-05 MA MA26587A patent/MA26826A1/fr unknown
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