OA11876A - Novel crystalline forms of a macrolide antibiotic. - Google Patents

Novel crystalline forms of a macrolide antibiotic. Download PDF

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Publication number
OA11876A
OA11876A OA1200100283A OA1200100283A OA11876A OA 11876 A OA11876 A OA 11876A OA 1200100283 A OA1200100283 A OA 1200100283A OA 1200100283 A OA1200100283 A OA 1200100283A OA 11876 A OA11876 A OA 11876A
Authority
OA
OAPI
Prior art keywords
crystalline form
compound
crystalline
formula
monohydrate
Prior art date
Application number
OA1200100283A
Other languages
English (en)
Inventor
Douglas John Meldrum Allen
Barry James Morton
Robert John Rafka
Colman Brendan Ragan
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of OA11876A publication Critical patent/OA11876A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
OA1200100283A 1999-05-18 2000-04-14 Novel crystalline forms of a macrolide antibiotic. OA11876A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13464499P 1999-05-18 1999-05-18

Publications (1)

Publication Number Publication Date
OA11876A true OA11876A (en) 2006-03-27

Family

ID=22464300

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200100283A OA11876A (en) 1999-05-18 2000-04-14 Novel crystalline forms of a macrolide antibiotic.

Country Status (43)

Country Link
US (1) US6583274B1 (de)
EP (1) EP1189912B1 (de)
JP (1) JP3897983B2 (de)
KR (1) KR100474229B1 (de)
CN (1) CN1203084C (de)
AP (1) AP2001002325A0 (de)
AR (1) AR020030A1 (de)
AT (1) ATE392427T1 (de)
AU (1) AU772283B2 (de)
BG (1) BG106150A (de)
BR (1) BR0011300A (de)
CA (1) CA2372206C (de)
CZ (1) CZ20014120A3 (de)
DE (1) DE60038610T2 (de)
DK (1) DK1189912T3 (de)
DZ (1) DZ3043A1 (de)
EA (1) EA003417B1 (de)
ES (1) ES2302689T3 (de)
GT (1) GT200000072A (de)
HK (1) HK1045521B (de)
HN (1) HN2000000056A (de)
HR (1) HRP20010849A2 (de)
HU (1) HUP0201341A3 (de)
IL (2) IL145946A0 (de)
IS (1) IS6127A (de)
MA (1) MA26735A1 (de)
MX (1) MXPA01011914A (de)
MY (1) MY133397A (de)
NO (1) NO320195B1 (de)
NZ (1) NZ514765A (de)
OA (1) OA11876A (de)
PA (1) PA8495001A1 (de)
PE (1) PE20010151A1 (de)
PL (1) PL353316A1 (de)
PT (1) PT1189912E (de)
SK (1) SK16472001A3 (de)
TN (1) TNSN00103A1 (de)
TW (1) TWI225066B (de)
UA (1) UA67842C2 (de)
UY (1) UY26144A1 (de)
WO (1) WO2000069874A1 (de)
YU (1) YU76601A (de)
ZA (1) ZA200109420B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
EP1250343B1 (de) * 2000-01-27 2003-06-25 Pfizer Products Inc. Antibiotische azalid-zusammensetzungen
MXPA03009786A (es) * 2001-04-27 2004-01-29 Pfizer Prod Inc Procedimiento para preparar derivados de 9-desoxo-9a-aza-9a-homoeritromicina a 4"-sustituidos.
EP1435359A1 (de) * 2002-12-31 2004-07-07 Alembic Limited Verfahren zur Reinigung von Roxithromycin
US7384921B2 (en) * 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
AR075340A1 (es) * 2009-01-30 2011-03-23 Glaxosmithkline Zagreb 3'-n-desmetil-4''-o-(2-dietilaminoetanoil)-6-o-metil-9a-aza-9a-homoeritromicina a,formas cristalinas 1, 2 y 3, proceso para su preparacion, composicion farmaceutica que lo comprende y su uso para la preparacion de un medicamento util para el tratamiento de enfermedades inflamatorias
EP2402355A1 (de) * 2010-07-01 2012-01-04 Novartis AG Kristalline wasserfreie Formen II und III von Tulathromycin
WO2013013834A1 (en) 2011-07-27 2013-01-31 Farma Grs, D.O.O. New crystalline forms of tulathromycin
CN106008622A (zh) * 2016-08-02 2016-10-12 海门慧聚药业有限公司 泰拉霉素新晶型及其制备
CN109942652B (zh) * 2017-12-21 2022-04-26 洛阳惠中兽药有限公司 一种莱柯霉素晶型ⅰ及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2066324C1 (ru) * 1987-07-09 1996-09-10 Пфайзер Инк. Кристаллический дигидрат азитромицина и способ его получения
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5844105A (en) * 1996-07-29 1998-12-01 Abbott Laboratories Preparation of crystal form II of clarithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
NO20015598D0 (no) 2001-11-16
DK1189912T3 (da) 2008-06-30
BR0011300A (pt) 2002-02-26
EP1189912A1 (de) 2002-03-27
IL145946A (en) 2007-06-17
HUP0201341A2 (en) 2002-08-28
AU772283B2 (en) 2004-04-22
IL145946A0 (en) 2002-07-25
ES2302689T3 (es) 2008-08-01
UY26144A1 (es) 2000-12-29
ZA200109420B (en) 2002-11-15
ATE392427T1 (de) 2008-05-15
JP2002544283A (ja) 2002-12-24
CA2372206A1 (en) 2000-11-23
UA67842C2 (uk) 2004-07-15
NO320195B1 (no) 2005-11-14
AR020030A1 (es) 2002-03-27
DE60038610T2 (de) 2009-06-25
HK1045521B (zh) 2005-12-09
NO20015598L (no) 2002-01-08
KR100474229B1 (ko) 2005-03-08
NZ514765A (en) 2004-05-28
TNSN00103A1 (fr) 2005-11-10
PA8495001A1 (es) 2002-02-21
AP2001002325A0 (en) 2001-12-31
DZ3043A1 (fr) 2004-03-27
MA26735A1 (fr) 2004-12-20
SK16472001A3 (sk) 2003-02-04
IS6127A (is) 2001-10-26
CA2372206C (en) 2006-01-10
JP3897983B2 (ja) 2007-03-28
DE60038610D1 (de) 2008-05-29
PE20010151A1 (es) 2001-02-08
BG106150A (bg) 2002-05-31
HRP20010849A2 (en) 2003-04-30
HN2000000056A (es) 2001-02-02
PL353316A1 (en) 2003-11-17
PT1189912E (pt) 2008-05-16
HK1045521A1 (en) 2002-11-29
EA200100984A1 (ru) 2002-06-27
EP1189912B1 (de) 2008-04-16
GT200000072A (es) 2001-11-08
CN1203084C (zh) 2005-05-25
AU3572900A (en) 2000-12-05
TWI225066B (en) 2004-12-11
EA003417B1 (ru) 2003-04-24
CN1351607A (zh) 2002-05-29
MY133397A (en) 2007-11-30
MXPA01011914A (es) 2002-05-06
KR20020007415A (ko) 2002-01-26
YU76601A (sh) 2004-09-03
CZ20014120A3 (cs) 2003-01-15
US6583274B1 (en) 2003-06-24
WO2000069874A1 (en) 2000-11-23
HUP0201341A3 (en) 2003-03-28

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