OA11453A - Methods for treatment of diabetes using peptide analogues of insulin. - Google Patents

Methods for treatment of diabetes using peptide analogues of insulin. Download PDF

Info

Publication number
OA11453A
OA11453A OA1200000229A OA1200000229A OA11453A OA 11453 A OA11453 A OA 11453A OA 1200000229 A OA1200000229 A OA 1200000229A OA 1200000229 A OA1200000229 A OA 1200000229A OA 11453 A OA11453 A OA 11453A
Authority
OA
OAPI
Prior art keywords
peptide
chain
insulin
cells
nbi
Prior art date
Application number
OA1200000229A
Other languages
English (en)
Inventor
Amitabh Gaur
Nicholas Ling
Paul J Conlon
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of OA11453A publication Critical patent/OA11453A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
OA1200000229A 1998-02-23 2000-08-22 Methods for treatment of diabetes using peptide analogues of insulin. OA11453A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2815698A 1998-02-23 1998-02-23

Publications (1)

Publication Number Publication Date
OA11453A true OA11453A (en) 2003-12-08

Family

ID=21841884

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200000229A OA11453A (en) 1998-02-23 2000-08-22 Methods for treatment of diabetes using peptide analogues of insulin.

Country Status (20)

Country Link
US (1) US6197926B1 (https=)
EP (1) EP1056776A1 (https=)
JP (1) JP2002504491A (https=)
KR (1) KR20010041238A (https=)
CN (1) CN1241942C (https=)
AP (1) AP2000001888A0 (https=)
AU (1) AU741037B2 (https=)
BR (1) BR9908178A (https=)
CA (1) CA2321929A1 (https=)
EA (1) EA003944B1 (https=)
HU (1) HUP0100928A3 (https=)
ID (1) ID26788A (https=)
IL (1) IL137904A0 (https=)
NO (1) NO20004198L (https=)
NZ (1) NZ506447A (https=)
OA (1) OA11453A (https=)
PL (1) PL342517A1 (https=)
SK (1) SK12412000A3 (https=)
TR (1) TR200003048T2 (https=)
WO (1) WO1999042482A1 (https=)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562942B1 (en) * 1999-02-23 2003-05-13 Neurocrine Biosciences, Inc. Methods for treatment of diabetes using peptide analogues of insulin
CN1125081C (zh) * 1999-09-08 2003-10-22 中国科学院上海生物化学研究所 重组天然和新型人胰岛素及其制备方法
US7462486B2 (en) * 2000-05-12 2008-12-09 Oregon Health & Science University Methods of selecting T cell receptor V peptides for therapeutic use
AU5984701A (en) * 2000-05-12 2001-11-20 Univ Oregon Health & Science Method of treating immune pathologies with low dose estrogen
US20020103131A1 (en) * 2001-01-26 2002-08-01 Jacobson Jill D. Prevention of diabetes by administration of GnRH antagonists
US20040138116A1 (en) * 2002-08-30 2004-07-15 Vincent Geenen Tolerogenic approach for type 1 diabetes
US20070172453A1 (en) * 2002-08-30 2007-07-26 Vincent Geenen Tolerogenic approach for type 1 diabetes
ZA200502613B (en) 2002-10-10 2006-10-25 Yeda Res & Dev Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents
CN1798569A (zh) * 2003-06-02 2006-07-05 莫西亚药物公司 用于治疗1型糖尿病的治疗性疫苗组合物
CA2575604A1 (en) * 2004-07-30 2006-02-02 Oregon Health And Science University Methods for detecting and treating autoimmune disorders
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
DE102008003566A1 (de) * 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
CN102007143B (zh) 2008-01-09 2015-08-26 塞诺菲-安万特德国有限公司 具有超延迟时效特征的新型胰岛素衍生物
AU2009210570B2 (en) 2008-01-30 2014-11-20 Indiana University Research And Technology Corporation Ester-based insulin prodrugs
CN102256618A (zh) 2008-10-17 2011-11-23 赛诺菲-安万特德国有限公司 胰岛素和glp-1激动剂的组合
WO2010080609A1 (en) 2008-12-19 2010-07-15 Indiana University Research And Technology Corporation Amide-based insulin prodrugs
WO2010080606A1 (en) * 2008-12-19 2010-07-15 Indiana University Research And Technology Corporation Insulin analogs
EP2496255A4 (en) 2009-11-05 2014-03-26 Mercia Pharma Inc ADJUVATED INFLUENZA VACCINE IN NANOPARTICLE FORM
NZ599847A (en) 2009-11-13 2013-09-27 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
TR201809460T4 (tr) 2009-11-13 2018-07-23 Sanofi Aventis Deutschland Bir GLP- 1-agonisti, bir insülin ve metiyonin içeren farmasötik bileşim.
US20110311536A1 (en) * 2010-06-11 2011-12-22 Dana-Farber Cancer Institute, Inc. Prevention of type 1 diabetes by treg vaccination with an insulin mimetope
EP2582719B1 (en) 2010-06-16 2016-08-10 Indiana University Research and Technology Corporation Single chain insulin agonists exhibiting high activity at the insulin receptor
JP5912112B2 (ja) 2010-06-24 2016-04-27 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation アミド系インスリンプロドラッグ
WO2012028172A1 (en) 2010-08-30 2012-03-08 Sanofi-Aventis Deutschland Gmbh Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
UA113626C2 (xx) * 2011-06-02 2017-02-27 Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
US9573987B2 (en) 2011-12-20 2017-02-21 Indiana University Research And Technology Corporation CTP-based insulin analogs for treatment of diabetes
AU2013323669B2 (en) 2012-09-26 2018-03-01 Indiana University Research And Technology Corporation Insulin analog dimers
WO2014158900A1 (en) 2013-03-14 2014-10-02 Indiana University Research And Technology Corporation Insulin-incretin conjugates
WO2016049174A1 (en) 2014-09-24 2016-03-31 Indiana University Research And Technology Corporation Lipidated amide-based insulin prodrugs
ES2822994T3 (es) 2014-09-24 2021-05-05 Univ Indiana Res & Tech Corp Conjugados de incretina-insulina
PE20171622A1 (es) 2014-12-12 2017-11-02 Sanofi Aventis Deutschland Formulacion de relacion fija de insulina glargina/lixisenatida
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
CN111925420B (zh) * 2019-12-11 2022-04-01 山东大学 一种多肽作为嗅觉受体Olfr109激动剂配体的应用
USD1043348S1 (en) * 2021-09-24 2024-09-24 H.J. Heinz Company Brands Llc Bottle

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
US5559094A (en) * 1994-08-02 1996-09-24 Eli Lilly And Company AspB1 insulin analogs
US5594100A (en) * 1995-02-22 1997-01-14 Regents Of The University Of Colorado Epitope for prevention of type I diabetes
EP0835129B1 (en) * 1995-06-30 2003-10-29 Novo Nordisk A/S Prevention of a disease having the characteristics of diabetes

Also Published As

Publication number Publication date
US6197926B1 (en) 2001-03-06
CN1294597A (zh) 2001-05-09
KR20010041238A (ko) 2001-05-15
NO20004198L (no) 2000-10-20
SK12412000A3 (sk) 2002-05-09
CN1241942C (zh) 2006-02-15
BR9908178A (pt) 2002-01-15
IL137904A0 (en) 2001-10-31
NZ506447A (en) 2002-11-26
PL342517A1 (en) 2001-06-18
TR200003048T2 (tr) 2000-12-21
HUP0100928A2 (hu) 2001-08-28
ID26788A (id) 2001-02-08
EA003944B1 (ru) 2003-10-30
CA2321929A1 (en) 1999-08-26
AP2000001888A0 (en) 2000-09-30
AU2783199A (en) 1999-09-06
HUP0100928A3 (en) 2001-11-28
JP2002504491A (ja) 2002-02-12
EP1056776A1 (en) 2000-12-06
EA200000872A1 (ru) 2001-02-26
AU741037B2 (en) 2001-11-22
WO1999042482A1 (en) 1999-08-26
NO20004198D0 (no) 2000-08-22

Similar Documents

Publication Publication Date Title
US6197926B1 (en) Methods for treatment of diabetes using peptide analogues of insulin
EP0246753B1 (en) Fibroblast growth factor antagonists
CA2182795C (en) Superactive vip antagonists
JPH10509714A (ja) ヒトミエリン塩基性タンパク質の91位におけるペプチドアナログを用いる多発性硬化症の処置方法
KR102117216B1 (ko) 강력한 작용제 효과를 지닌 신규한 gh-rh 유사체
EP0605983A2 (en) Insulin analogs
JPH10511088A (ja) 免疫調節活性を有するペプチド
AU713067B2 (en) Cyclic peptide vaccines for treatment and prevention of diabetes
JPH10509460A (ja) 自己免疫疾患の進行を阻害するための処理方法
US6562942B1 (en) Methods for treatment of diabetes using peptide analogues of insulin
JP2002507886A (ja) アンギオテンシン誘導体
EP0785947B1 (en) Peptides endowed with antiinflammatory activity
AU781405B2 (en) Methods for treatment of diabetes using peptide analogues of insulin
HUP0000836A2 (hu) Kollagén II-re specifikus T-sejt epitópot tartalmazó peptidek
MXPA00008268A (en) Methods for treatment of diabetes using peptide analogues of insulin
CZ20003065A3 (cs) Peptidové analogy insulinu a jejich využití pro léčení diabetes mellitus
AU6910494A (en) Amylin antagonists and agonists
JP2000229997A (ja) 環状ペプチド及びエイズワクチン
AU6478696A (en) Methods for treatment and prevention of diabetes
KR102204476B1 (ko) 다발성 경화증 치료 및 예방용 조성물
AU1495700A (en) Methods for treatment and prevention of diabetes
HK1110352A (en) Immunoreactive and immunotherapeutic molecules which interact in subjects with insulin-dependent diabetes mellitus (iddm)
CA2566828A1 (en) Immunoreactive and immunotherapeutic molecules which interact in subjects with insulin-dependent diabetes mellitus (iddm)