OA10145A - Procédé de préparation du ginkgolide B à partir du ginkgolide C - Google Patents

Procédé de préparation du ginkgolide B à partir du ginkgolide C Download PDF

Info

Publication number
OA10145A
OA10145A OA60645A OA60645A OA10145A OA 10145 A OA10145 A OA 10145A OA 60645 A OA60645 A OA 60645A OA 60645 A OA60645 A OA 60645A OA 10145 A OA10145 A OA 10145A
Authority
OA
OAPI
Prior art keywords
ginkgolide
process according
reaction
borohydride
carried out
Prior art date
Application number
OA60645A
Other languages
English (en)
French (fr)
Inventor
Jean-Bernard Cazaux
Michel Dafniet
Jacques Rebollo
Beng-Poon Teng
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of OA10145A publication Critical patent/OA10145A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
OA60645A 1994-04-22 1995-04-21 Procédé de préparation du ginkgolide B à partir du ginkgolide C OA10145A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9408044A GB9408044D0 (en) 1994-04-22 1994-04-22 Conversion of ginkgolide c to ginkgolide b

Publications (1)

Publication Number Publication Date
OA10145A true OA10145A (fr) 1996-12-18

Family

ID=10753985

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60645A OA10145A (fr) 1994-04-22 1995-04-21 Procédé de préparation du ginkgolide B à partir du ginkgolide C

Country Status (23)

Country Link
US (1) US5599950A (ko)
EP (1) EP0680968B1 (ko)
JP (1) JP2992575B2 (ko)
KR (1) KR950032203A (ko)
AT (1) ATE189817T1 (ko)
AU (1) AU684338B2 (ko)
CA (1) CA2147423C (ko)
DE (1) DE69515077T2 (ko)
DK (1) DK0680968T3 (ko)
DZ (1) DZ1874A1 (ko)
ES (1) ES2144585T3 (ko)
FI (1) FI109907B (ko)
FR (1) FR2719046B1 (ko)
GB (2) GB9408044D0 (ko)
IE (1) IE80950B1 (ko)
MY (1) MY113056A (ko)
NO (1) NO310557B1 (ko)
NZ (1) NZ270925A (ko)
OA (1) OA10145A (ko)
RU (1) RU2145326C1 (ko)
TN (1) TNSN95041A1 (ko)
TW (1) TW300897B (ko)
ZA (1) ZA952986B (ko)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981902A (en) * 1994-12-15 1999-11-09 Mitsubishi Chemical Corporation Texturing apparatus for magnetic recording medium and magnetic recording medium process thereby
AU4981397A (en) * 1996-10-16 1998-05-11 Merck & Co., Inc. Triterpene derivatives with immunosupressant activity
WO1998016532A1 (en) * 1996-10-16 1998-04-23 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
US6083980A (en) * 1997-10-17 2000-07-04 Merck & Co., Inc. Furanyl, tetracyclic triterpene derivatives with immunosuppressant activity
US6100293A (en) * 1997-10-17 2000-08-08 Merck & Co., Inc. Tetracyclic triterpene derivatives with immunosuppressant activity
US6022890A (en) * 1997-11-14 2000-02-08 Merck & Co., Inc. Immunosuppressant tetracyclic triterpenes
US6030621A (en) 1998-03-19 2000-02-29 De Long; Xie Ginkgo biloba composition, method to prepare the same and uses thereof
US6051590A (en) * 1999-05-13 2000-04-18 Merck & Co., Inc. Immunosuppressant tricyclic compounds
US6946283B2 (en) * 2001-01-05 2005-09-20 William Marsh Rice University Ginkgo biloba levopimaradiene synthase
US7238514B2 (en) * 2001-01-05 2007-07-03 William Marsh Rice University Diterpene-producing unicellular organism
FR2823116B1 (fr) * 2001-04-10 2004-11-19 Sod Conseils Rech Applic Procede de preparation d'une extrait de feuilles de ginkgo biloba hautement enrichi en principes actifs
US7145021B2 (en) * 2002-03-29 2006-12-05 The Trustees Of Columbia University In The City Of New York Analogs of terpene trilactones from Ginkgo biloba and related compounds and uses thereof
US6693091B2 (en) 2002-03-29 2004-02-17 The Trustees Of Columbia University In The City Of New York Analogs of terpene trilactones from Ginkgo biloba for bioorganic and imaging studies
US7429670B2 (en) * 2003-08-27 2008-09-30 The Trustees Of Columbia University In The City Of New York Synthesis of derivatives of ginkgolide C
WO2005046829A2 (en) 2003-11-12 2005-05-26 The Trustees Of Columbia University In The City Of New York Separation of ginkgolides and bilobalide from g. biloba
US20090156668A1 (en) * 2004-03-19 2009-06-18 The Trustees Of Columbia University In The City Of New York Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof
US20080306145A1 (en) * 2004-11-23 2008-12-11 The Trustees Of Columbia University In The City Of New York Preparation Of Ginkgolide And F-Seco-Ginkgolide Lactols
WO2007002410A2 (en) * 2005-06-22 2007-01-04 The Trustees Of Columbia University In The City Of New York Core-modified terpene trilactones from ginkgo biloba extract and biological evaluation thereof
CN102382121A (zh) * 2010-09-02 2012-03-21 秦引林 银杏内酯衍生物及其在制药中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
KR940002795B1 (ko) * 1989-06-16 1994-04-02 주식회사 선경인더스트리 은행잎에서 징코라이드를 분리 및 정제하는 방법
GB9107425D0 (en) * 1991-04-09 1991-05-22 Scras Preparation of ginkgolide b

Also Published As

Publication number Publication date
IE950265A1 (en) 1995-11-01
RU95106678A (ru) 1997-01-10
FR2719046B1 (fr) 1999-03-19
TW300897B (ko) 1997-03-21
DE69515077T2 (de) 2000-09-14
IE80950B1 (en) 1999-07-14
CA2147423C (en) 2005-06-21
NO951524L (no) 1995-10-23
FR2719046A1 (fr) 1995-10-27
KR950032203A (ko) 1995-12-20
ZA952986B (en) 1995-12-21
AU1656695A (en) 1995-11-02
EP0680968B1 (fr) 2000-02-16
EP0680968A1 (fr) 1995-11-08
AU684338B2 (en) 1997-12-11
GB9507801D0 (en) 1995-05-31
JP2992575B2 (ja) 1999-12-20
MY113056A (en) 2001-11-30
GB2288599A (en) 1995-10-25
NO951524D0 (no) 1995-04-21
ATE189817T1 (de) 2000-03-15
DE69515077D1 (de) 2000-03-23
TNSN95041A1 (fr) 1996-02-06
ES2144585T3 (es) 2000-06-16
JPH07291975A (ja) 1995-11-07
GB9408044D0 (en) 1994-06-15
GB2288599B (en) 1998-04-22
DK0680968T3 (da) 2000-07-31
US5599950A (en) 1997-02-04
RU2145326C1 (ru) 2000-02-10
FI951903A0 (fi) 1995-04-21
FI951903A (fi) 1995-10-23
FI109907B (fi) 2002-10-31
CA2147423A1 (en) 1995-10-23
NZ270925A (en) 1996-03-26
DZ1874A1 (fr) 2002-02-17
NO310557B1 (no) 2001-07-23

Similar Documents

Publication Publication Date Title
OA10145A (fr) Procédé de préparation du ginkgolide B à partir du ginkgolide C
FR2599739A1 (fr) Acides biphenyl hydroxamiques a action therapeutique
EP0406112B1 (fr) 1-Benzhydrylazétidines, leur préparation et leur application comme intermédiaires pour la préparation de composés à activité antimicrobienne
CH652726A5 (fr) Derives steroides 17-oxazolines, leur procede de preparation et leur utilisation a la preparation de corticosteroides.
CA2098185A1 (fr) Procede de preparation de derives de l'acide dihydroxy-3,5 pentanoique
EP1856080B1 (fr) Procede de preparation du docetaxel
EP3063166B1 (fr) Procede de preparation de derives steroidiens 6-alkylés et les 5,6,7,8-tetrahydronaphthalène-2(4alpha.h)-ones alkylés correspondants
EP0772630B1 (fr) Derives de streptogramine, leur preparation et les compositions pharmaceutiques qui les contiennent
WO1996038447A1 (fr) Derives du 2-azabicyclo[2.2.1]heptane, leur preparation et leur application
EP1458724B1 (fr) Synthese totale de la galanthamine, de ses analogues et de ses derives
EP0828740B1 (fr) Derives du 2-azabicyclo[2.2.1]heptane, leur preparation et leur application
EP1095937B1 (fr) Procédé de préparation d'oxazoles trisubstitués
EP0432029A1 (fr) Procédé de préparation de synergistines
FR2667065A1 (fr) Procede pour preparer la 1-[(2s)-3-mercapto-2-methyl-1-oxopropyl]-l-proline.
KR100679115B1 (ko) 1-알파-히드록시콜레칼시페롤 유도체의 제조방법
EP0193450A2 (fr) Procédé de préparation de diphénylazométhines
BE830215A (fr) Procede d'obtention de n ino.-i-(2exp.2 furanidil)-3-uraciles substitue
CA2430302A1 (fr) Procede de cyclisation pour la synthese de composes derives de pyrrolidine
FR2746797A1 (fr) Nouveaux derives du 10-acetyldocetaxel et leur procede de preparation
FR2642426A1 (fr) Compose d'organogermanium, procedes pour leur fabrication et agent inhibiteur des enzymes de degradation des peptides opioides
PL110718B2 (en) Method of producing new derivatives of 3-desoxy-dl-streptose
FR2534583A1 (fr) Procede pour la fabrication d'hexahydro-5-hydroxy-4-hydroxymethyl-2h-cyclopenta-(b)-furanne-2-one
FR2914642A1 (fr) Procede de preparation de taxanes 3'-n-substitues a partir du paclitaxel
CH439279A (fr) Procédé de préparation de bis-hydroxyméthylène-pregnane
BE896093A (fr) Procede d'obtention d'alpha-chloronitroso-alcanes dimeres et alpha-chloronitroso-alcanes dimeres obtenus par ledit procede