OA10090A - Process of preparing 3-carbonylandrostadiene 17-carboxamides - Google Patents

Process of preparing 3-carbonylandrostadiene 17-carboxamides Download PDF

Info

Publication number
OA10090A
OA10090A OA60547A OA60547A OA10090A OA 10090 A OA10090 A OA 10090A OA 60547 A OA60547 A OA 60547A OA 60547 A OA60547 A OA 60547A OA 10090 A OA10090 A OA 10090A
Authority
OA
OAPI
Prior art keywords
compound
process according
formula
cyanide
nitrogen
Prior art date
Application number
OA60547A
Other languages
English (en)
Inventor
Neil Howard Baine
Lillian Owings
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of OA10090A publication Critical patent/OA10090A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
OA60547A 1992-02-07 1994-08-03 Process of preparing 3-carbonylandrostadiene 17-carboxamides OA10090A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83228092A 1992-02-07 1992-02-07

Publications (1)

Publication Number Publication Date
OA10090A true OA10090A (en) 1996-12-18

Family

ID=25261209

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60547A OA10090A (en) 1992-02-07 1994-08-03 Process of preparing 3-carbonylandrostadiene 17-carboxamides

Country Status (23)

Country Link
EP (1) EP0643724A4 (ko)
JP (1) JPH07505140A (ko)
KR (1) KR950700319A (ko)
CN (1) CN1078475A (ko)
AP (1) AP9600790A0 (ko)
AU (1) AU666177B2 (ko)
BG (1) BG98955A (ko)
BR (1) BR9305837A (ko)
CA (1) CA2129342A1 (ko)
CZ (1) CZ188794A3 (ko)
FI (1) FI943660A0 (ko)
HU (1) HUT68303A (ko)
IL (1) IL104602A (ko)
MA (1) MA22788A1 (ko)
MX (1) MX9300676A (ko)
NO (1) NO942925L (ko)
NZ (1) NZ249382A (ko)
OA (1) OA10090A (ko)
RU (1) RU94045824A (ko)
SI (1) SI9300065A (ko)
TW (1) TW327175B (ko)
WO (1) WO1993016097A1 (ko)
ZA (1) ZA93801B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9206413D0 (en) * 1992-03-24 1992-05-06 Smithkline Beecham Corp N-t-butyl-androst-3,5-diene-17b-carboxamide-3-carboxylic acid polymorph a
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA883034B (en) * 1987-04-29 1989-03-29 Smithkline Beckman Corp Steroid 5-alpha-reductase inhibitors
IL104601A0 (en) * 1992-02-07 1993-07-08 Smithkline Beecham Corp Process for the preparation of steroidal dienes

Also Published As

Publication number Publication date
RU94045824A (ru) 1996-07-10
KR950700319A (ko) 1995-01-16
EP0643724A1 (en) 1995-03-22
FI943660A (fi) 1994-08-05
AU3612693A (en) 1993-09-03
BG98955A (bg) 1995-06-30
HUT68303A (en) 1995-06-28
AP9600790A0 (en) 1996-04-30
WO1993016097A1 (en) 1993-08-19
SI9300065A (en) 1993-09-30
EP0643724A4 (en) 1995-05-10
NO942925L (no) 1994-08-08
JPH07505140A (ja) 1995-06-08
CN1078475A (zh) 1993-11-17
CA2129342A1 (en) 1993-08-19
IL104602A (en) 1997-07-13
FI943660A0 (fi) 1994-08-05
HU9402303D0 (en) 1994-10-28
NZ249382A (en) 1996-05-28
BR9305837A (pt) 1997-02-18
NO942925D0 (ko) 1994-08-05
AU666177B2 (en) 1996-02-01
ZA93801B (en) 1993-11-05
MX9300676A (es) 1994-07-29
IL104602A0 (en) 1993-07-08
MA22788A1 (fr) 1993-10-01
CZ188794A3 (en) 1994-12-15
TW327175B (en) 1998-02-21

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