NZ782016A - Biomarkers of traumatic brain injury - Google Patents

Biomarkers of traumatic brain injury

Info

Publication number
NZ782016A
NZ782016A NZ782016A NZ78201617A NZ782016A NZ 782016 A NZ782016 A NZ 782016A NZ 782016 A NZ782016 A NZ 782016A NZ 78201617 A NZ78201617 A NZ 78201617A NZ 782016 A NZ782016 A NZ 782016A
Authority
NZ
New Zealand
Prior art keywords
tbi
mir
subject
brain injury
traumatic brain
Prior art date
Application number
NZ782016A
Other languages
English (en)
Inventor
Antonio Belli
Pietro Valentina Di
Original Assignee
Univ Birmingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Birmingham filed Critical Univ Birmingham
Priority claimed from NZ745808A external-priority patent/NZ745808B2/en
Publication of NZ782016A publication Critical patent/NZ782016A/en

Links

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NZ782016A 2016-03-08 2017-01-30 Biomarkers of traumatic brain injury NZ782016A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1603967.9A GB201603967D0 (en) 2016-03-08 2016-03-08 Biomarkers of traumatic brain injury
NZ745808A NZ745808B2 (en) 2017-01-30 Biomarkers of traumatic brain injury

Publications (1)

Publication Number Publication Date
NZ782016A true NZ782016A (en) 2025-07-25

Family

ID=55859162

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ782016A NZ782016A (en) 2016-03-08 2017-01-30 Biomarkers of traumatic brain injury

Country Status (14)

Country Link
US (5) US20190085395A1 (enExample)
EP (7) EP3426796B1 (enExample)
JP (5) JP7111619B2 (enExample)
KR (4) KR20240167935A (enExample)
CN (4) CN116004796A (enExample)
AU (3) AU2017231845B2 (enExample)
CA (2) CA3015150A1 (enExample)
ES (4) ES2967073T3 (enExample)
GB (1) GB201603967D0 (enExample)
NZ (1) NZ782016A (enExample)
PL (2) PL3712277T3 (enExample)
UA (1) UA127918C2 (enExample)
WO (2) WO2017153710A1 (enExample)
ZA (1) ZA201805982B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3122905B1 (en) 2014-03-27 2020-09-09 Yale University Circulating micrornas as biomarkers for endometriosis
GB201603967D0 (en) 2016-03-08 2016-04-20 Univ Birmingham Biomarkers of traumatic brain injury
MX2019002425A (es) * 2016-08-30 2019-08-16 Univ Yale Micro ácidos ribonucleicos como biomarcadores para la endometriosis.
WO2018175941A1 (en) * 2017-03-23 2018-09-27 Quadrant Biosciences Inc. Analysis and prediction of traumatic brain injury and concusion symptoms
US11739323B2 (en) * 2017-06-08 2023-08-29 Temple University-Of The Commonwealth System Of Higher Education Micro-RNAs as biomarkers for subconcussive and concussive injury and therapeutic applications
EP3803416A4 (en) * 2018-05-31 2022-05-18 Amydis, Inc. COMPOSITIONS AND METHODS FOR DETECTING BRAIN TRAUMA
SG10201807529VA (en) * 2018-09-03 2020-04-29 Nec Asia Pacific Pte Ltd Systems and methods for predicting recovery of a patient
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
PE20220877A1 (es) * 2019-02-14 2022-05-27 Marker Diagnostics Uk Ltd Biomarcadores salivales de lesion cerebral
KR102184840B1 (ko) * 2019-05-20 2020-11-30 이화여자대학교 산학협력단 외상 후 스트레스 장애 진단 또는 예측용 바이오마커 및 그의 용도
US11965879B2 (en) * 2019-08-23 2024-04-23 Mcmaster University Method for diagnosing and assessing endometriosis
KR102272915B1 (ko) 2019-09-27 2021-07-06 주식회사 이지다이아텍 새로운 외상성 뇌손상 및 감염병 poct 진단시스템
CN110684835A (zh) * 2019-10-12 2020-01-14 山东大学齐鲁医院 miR-21在诊治蛛网膜下腔出血中的应用
CN111419866A (zh) * 2020-03-02 2020-07-17 南通大学 miR-29a-3p在制备治疗周围神经损伤药物中的应用
US12157918B2 (en) * 2020-09-04 2024-12-03 University Of Kentucky Research Foundation Clinical assessment of cerebral vasospasm risk following aneurysmal subarachnoid hemorrhage
IL307369A (en) 2021-04-02 2023-11-01 Marker Holdings Ag Biomarkers of muscle and skeletal injury
CN116219019A (zh) * 2023-03-02 2023-06-06 圣湘生物科技股份有限公司 一种用于结直肠癌诊断的microRNA标志物组合物及检测试剂、检测试剂盒
WO2024242411A1 (ko) 2023-05-19 2024-11-28 주식회사 이지다이아텍 자동 항체 커플링 및 이를 확인하는 장치
WO2025039033A1 (en) * 2023-08-21 2025-02-27 Glia Diagnostics Pty Ltd Methods and reagents for diagnosis and/or prognosis of traumatic brain injury

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH31414A (en) 1994-02-24 1998-10-29 Boehringer Ingelheim Int Method of diagnosing cancer precancerous state, orsusceptibility to other forms of diseases by anal ysis of irf-1 specific rna in biopsy samples.
WO1999033018A1 (de) 1997-12-18 1999-07-01 Infineon Technologies Ag Vorrichtung zur bilderfassung
RU66524U1 (ru) 2007-05-03 2007-09-10 Федор Андреевич Егоров Сооружение, в котором обеспечена возможность комплексного мониторинга сооружения
CN101424640B (zh) 2007-11-02 2012-07-25 江苏命码生物科技有限公司 血清中微小核糖核酸的检测方法和用于检测的试剂盒、生物芯片及其制作和应用方法
DE102008017652A1 (de) 2008-04-04 2009-10-08 Leonhard Kurz Stiftung & Co. Kg Sicherheitselement sowie Verfahren zur Herstellung eines Sicherheitselements
EP2336353A1 (en) 2009-12-17 2011-06-22 febit holding GmbH miRNA fingerprints in the diagnosis of diseases
HUE040281T2 (hu) * 2009-09-14 2019-03-28 Banyan Biomarkers Inc Autoantitest markerek traumás agysérülés diagnózisára
RU93660U1 (ru) 2010-02-08 2010-05-10 Государственное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "РостГМУ Росздрава") Тест-полоска для диагностики нефропатии
CN103237901B (zh) * 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物
WO2013159091A2 (en) * 2012-04-20 2013-10-24 Aptamir Therapeutics, Inc. Mirna modulators of thermogenesis
US20150203916A1 (en) 2012-06-27 2015-07-23 Music Foundation For Research Development Plasma analytes predict diagnosis and prognosis of thoracic aortic aneurysm
GB201223243D0 (en) * 2012-12-21 2013-02-06 King S College London Detection method
EP3418430B1 (en) 2013-03-15 2023-03-29 The Trustees of the University of Pennsylvania Blood biomarkers that predict persistent cognitive dysfunction after concussion
US9890428B2 (en) * 2013-05-14 2018-02-13 Ohio State Innovation Foundation MiRNA biomarkers for radiation biodosimetry
US9434945B2 (en) * 2013-08-02 2016-09-06 University Of Maryland, Baltimore Use of miR-23a-3p and/or miR-27a-3p mimics as therapeutic agents for inhibition of neuronal apoptosis following brain injury
CN103667445A (zh) * 2013-10-16 2014-03-26 石磊 一种脑梗塞早期诊断标志物及其应用
WO2015073972A1 (en) * 2013-11-18 2015-05-21 Diamir, Llc METHODS OF USING mIRNAs FROM BODILY FLUIDS FOR DETECTION AND MONITORING OF PARKINSON'S DISEASE (PD)
WO2015128192A1 (en) * 2014-02-26 2015-09-03 Koninklijke Philips N.V. Light reflectance based detection
WO2015134551A1 (en) * 2014-03-03 2015-09-11 Banyan Biomarkers, Inc. Micro rna markers for diagnosis of a neurological condition
US9605315B2 (en) * 2014-03-26 2017-03-28 The University Of Montana Detection of traumatic brain injury
WO2015153864A2 (en) 2014-04-02 2015-10-08 Hopkins Patricia T Methods for treating inflammatory conditions
WO2015164431A2 (en) * 2014-04-22 2015-10-29 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Methods, processes, devices and kits for the measurement of post traumatic stress disorder microrna markers
WO2015196191A1 (en) * 2014-06-20 2015-12-23 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Microrna biomarkers for traumatic brain injury and methods of use thereof
ES2558262B2 (es) 2014-08-01 2016-07-14 Universidad Católica De Valencia "San Vicente Mártir" Método de diagnóstico de fibromialgia basado en microRNAs
CN104293791B (zh) * 2014-10-22 2018-01-12 首都医科大学附属北京友谊医院 miR‑200b在制备Rac‑1蛋白表达抑制剂中的新用途
CA2993989A1 (en) * 2015-07-29 2017-02-02 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Microrna biomarkers for traumatic brain injury and methods of use thereof
WO2017044650A1 (en) 2015-09-08 2017-03-16 The Translational Genomics Research Institute Biomarkers and methods of diagnosing and prognosing mild traumatic brain injuries
GB201603967D0 (en) 2016-03-08 2016-04-20 Univ Birmingham Biomarkers of traumatic brain injury
WO2018175941A1 (en) 2017-03-23 2018-09-27 Quadrant Biosciences Inc. Analysis and prediction of traumatic brain injury and concusion symptoms
WO2018175422A1 (en) 2017-03-23 2018-09-27 Quadrant Biosciences Inc. Method for diagnosing or monitoring conditions characterized by abnormal temporal variations method of normalizing epigenetic data to compensate for temporal variations
PE20220877A1 (es) 2019-02-14 2022-05-27 Marker Diagnostics Uk Ltd Biomarcadores salivales de lesion cerebral

Also Published As

Publication number Publication date
KR102729795B1 (ko) 2024-11-14
GB201603967D0 (en) 2016-04-20
EP3574117B1 (en) 2023-08-16
HK1258615A1 (zh) 2019-11-15
JP2024041804A (ja) 2024-03-27
EP3712280B1 (en) 2023-08-09
EP4257705C0 (en) 2025-04-23
EP3712280B8 (en) 2023-09-13
ZA201805982B (en) 2022-01-26
CN109415769A (zh) 2019-03-01
JP7132224B2 (ja) 2022-09-06
CN110291210A (zh) 2019-09-27
WO2018138468A1 (en) 2018-08-02
CA3015150A1 (en) 2017-09-14
AU2023282212B2 (en) 2025-10-16
UA127918C2 (uk) 2024-02-14
AU2017231845B2 (en) 2023-09-28
JP7111619B2 (ja) 2022-08-02
EP4582559A2 (en) 2025-07-09
EP4403649A3 (en) 2024-10-30
CN118441040A (zh) 2024-08-06
EP3426796B1 (en) 2023-09-06
KR20180118670A (ko) 2018-10-31
EP4582559A3 (en) 2025-10-08
EP3574117A1 (en) 2019-12-04
CN110291210B (zh) 2024-05-28
KR102618993B1 (ko) 2023-12-28
JP2025098112A (ja) 2025-07-01
RU2018135107A (ru) 2020-04-08
RU2018135107A3 (enExample) 2020-12-14
ES2967073T3 (es) 2024-04-25
JP2020511953A (ja) 2020-04-23
AU2017231845A1 (en) 2018-09-13
US20200385808A1 (en) 2020-12-10
US12467095B2 (en) 2025-11-11
ES3032995T3 (en) 2025-07-29
EP3712280A1 (en) 2020-09-23
US20180127828A1 (en) 2018-05-10
BR112018067882A2 (pt) 2019-02-05
WO2017153710A1 (en) 2017-09-14
US11414705B2 (en) 2022-08-16
AU2023282212A1 (en) 2024-01-04
KR20240011189A (ko) 2024-01-25
PL3712277T3 (pl) 2025-02-10
ES2965297T3 (es) 2024-04-12
KR20240167935A (ko) 2024-11-28
ES2987237T3 (es) 2024-11-14
EP3712277B1 (en) 2024-06-12
CN109415769B (zh) 2022-09-30
EP3712277C0 (en) 2024-06-12
JP2019509044A (ja) 2019-04-04
JP2022163063A (ja) 2022-10-25
US20230295726A1 (en) 2023-09-21
US10563262B2 (en) 2020-02-18
AU2025263788A1 (en) 2025-11-27
US20190085395A1 (en) 2019-03-21
US20230313300A1 (en) 2023-10-05
PL4257705T3 (pl) 2025-08-18
CA3050996A1 (en) 2018-08-02
NZ745808A (en) 2024-09-27
EP3712277A1 (en) 2020-09-23
EP4403649A2 (en) 2024-07-24
EP4257705A3 (en) 2024-01-17
JP7413455B2 (ja) 2024-01-15
KR20190111967A (ko) 2019-10-02
EP3426796A1 (en) 2019-01-16
JP7654769B2 (ja) 2025-04-01
CN116004796A (zh) 2023-04-25
EP4257705A2 (en) 2023-10-11
EP4257705B1 (en) 2025-04-23

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