WO2016112174A3 - Biomarkers of Sleep Deprivation and Cognitive Impairment - Google Patents
Biomarkers of Sleep Deprivation and Cognitive Impairment Download PDFInfo
- Publication number
- WO2016112174A3 WO2016112174A3 PCT/US2016/012453 US2016012453W WO2016112174A3 WO 2016112174 A3 WO2016112174 A3 WO 2016112174A3 US 2016012453 W US2016012453 W US 2016012453W WO 2016112174 A3 WO2016112174 A3 WO 2016112174A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biomarkers
- sleep deprivation
- cognitive impairment
- identifying
- subject suspected
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2864—Sleep disorders
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention includes a method of identifying a subject suspected of sleep deprivation. The method comprises testing a set of biomarkers in a test sample and comparing the test level with the baseline level. The invention also includes a method of identifying a subject suspected of having cognitive impairment as a result of sleep deprivation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562101047P | 2015-01-08 | 2015-01-08 | |
US62/101,047 | 2015-01-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2016112174A2 WO2016112174A2 (en) | 2016-07-14 |
WO2016112174A3 true WO2016112174A3 (en) | 2016-10-27 |
Family
ID=56356573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2016/012453 WO2016112174A2 (en) | 2015-01-08 | 2016-01-07 | Biomarkers of Sleep Deprivation and Cognitive Impairment |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2016112174A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4045905A4 (en) * | 2019-10-17 | 2023-10-11 | Biomark Cancer Systems Inc. | Method of diagnosing early-stage non-small cell lung cancer |
CN114544790B (en) * | 2020-11-24 | 2023-10-24 | 重庆医科大学 | Application of reagent for detecting lysophosphatidylethanolamine (22:5) in blood plasma in preparation of depression detection kit |
CN113552260B (en) * | 2021-07-23 | 2023-07-18 | 江苏省中医院 | Application of glycerol-3-galactoside in early diabetic nephropathy diagnosis |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
US20110218242A1 (en) * | 2005-07-08 | 2011-09-08 | Ellis Lorie A | Polyunsaturated Fatty Acids for Treatment of Dementia and Pre-Dementia-Related Conditions |
US20130054215A1 (en) * | 2011-08-29 | 2013-02-28 | Pulsar Informatics, Inc. | Systems and methods for apnea-adjusted neurobehavioral performance prediction and assessment |
US20130101984A1 (en) * | 2011-10-20 | 2013-04-25 | The Washington University | Methods of detecting sleepiness |
-
2016
- 2016-01-07 WO PCT/US2016/012453 patent/WO2016112174A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080009467A1 (en) * | 2000-05-01 | 2008-01-10 | Accera, Inc. | Combinations of medium chain triglycerides and therapeutic agents for the treatment and prevention of alzheimers disease and other diseases resulting from reduced neuronal metabolism |
US20110218242A1 (en) * | 2005-07-08 | 2011-09-08 | Ellis Lorie A | Polyunsaturated Fatty Acids for Treatment of Dementia and Pre-Dementia-Related Conditions |
US20130054215A1 (en) * | 2011-08-29 | 2013-02-28 | Pulsar Informatics, Inc. | Systems and methods for apnea-adjusted neurobehavioral performance prediction and assessment |
US20130101984A1 (en) * | 2011-10-20 | 2013-04-25 | The Washington University | Methods of detecting sleepiness |
Non-Patent Citations (5)
Title |
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BUCKS ET AL.: "Neurocognitive function in obstructive sleep apnoea:A meta-review.", RESPIROLOGY, vol. 18, no. 1, 31 January 2013 (2013-01-31), pages 61 - 70, XP055324793 * |
DAVIES ET AL.: "Effect of sleep deprivation on the human metabolome.", PROC. NATL. ACAD. SCI., vol. 111, no. 29, 22 July 2014 (2014-07-22), pages 10761 - 10766, XP055324781 * |
GOOLEY ET AL.: "Diurnal Regulation of Lipid Metabolism and Applications of Circadian Lipidomics.", J. GENET. GENOMICS, vol. 41, no. 5, 20 May 2014 (2014-05-20), pages 231 - 250, XP055324791 * |
THOMANN ET AL.: "Psychomotor Vigilance Task Demonstrates Impaired Vigilance in Disorders with Excessive Daytime Sleepiness.", J CLIN SLEEP MED., vol. 10, no. 9, 15 September 2014 (2014-09-15), pages 1019 - 1024, XP055324787 * |
WITTERT: "The relationship between sleep disorders and testosterone in men.", ASIAN J ANDROL., vol. 16, no. 2, 30 April 2014 (2014-04-30), pages 262 - 265, XP055324796 * |
Also Published As
Publication number | Publication date |
---|---|
WO2016112174A2 (en) | 2016-07-14 |
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