NZ626242A - Anti-asic1 antibodies and uses thereof - Google Patents

Anti-asic1 antibodies and uses thereof

Info

Publication number
NZ626242A
NZ626242A NZ626242A NZ62624213A NZ626242A NZ 626242 A NZ626242 A NZ 626242A NZ 626242 A NZ626242 A NZ 626242A NZ 62624213 A NZ62624213 A NZ 62624213A NZ 626242 A NZ626242 A NZ 626242A
Authority
NZ
New Zealand
Prior art keywords
asic1
antibodies
asic1 antibodies
antigen
disorders
Prior art date
Application number
NZ626242A
Other languages
English (en)
Inventor
Lynn Macdonald
Min Gao
Marc R Morra
Nicole M Alessandri-Haber
Michael L Lacroix-Fralish
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47666522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ626242(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of NZ626242A publication Critical patent/NZ626242A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ626242A 2012-01-31 2013-01-30 Anti-asic1 antibodies and uses thereof NZ626242A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261592837P 2012-01-31 2012-01-31
US201261644038P 2012-05-08 2012-05-08
US201261692925P 2012-08-24 2012-08-24
PCT/US2013/023784 WO2013116296A1 (en) 2012-01-31 2013-01-30 Anti-asic1 antibodies and uses thereof

Publications (1)

Publication Number Publication Date
NZ626242A true NZ626242A (en) 2017-02-24

Family

ID=47666522

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ626242A NZ626242A (en) 2012-01-31 2013-01-30 Anti-asic1 antibodies and uses thereof

Country Status (33)

Country Link
US (3) US9150648B2 (https=)
EP (2) EP3453723B1 (https=)
JP (1) JP6302844B2 (https=)
KR (1) KR102111941B1 (https=)
CN (1) CN104093738B (https=)
AR (1) AR089852A1 (https=)
AU (1) AU2013215254B2 (https=)
CA (1) CA2862332C (https=)
CL (1) CL2014002019A1 (https=)
CO (1) CO7020877A2 (https=)
CY (2) CY1121368T1 (https=)
DK (2) DK3453723T3 (https=)
EA (1) EA028647B1 (https=)
ES (2) ES2886123T3 (https=)
HR (2) HRP20211541T1 (https=)
HU (2) HUE056335T2 (https=)
IL (2) IL233410A0 (https=)
IN (1) IN2014CN04645A (https=)
JO (1) JO3547B1 (https=)
LT (2) LT2809681T (https=)
MX (1) MX358518B (https=)
MY (1) MY168748A (https=)
NZ (1) NZ626242A (https=)
PH (1) PH12014501613B1 (https=)
PL (2) PL3453723T3 (https=)
PT (2) PT3453723T (https=)
RS (2) RS62454B1 (https=)
SG (1) SG11201403222UA (https=)
SI (2) SI3453723T1 (https=)
SM (1) SMT202100628T1 (https=)
TW (1) TWI591073B (https=)
UY (1) UY34603A (https=)
WO (1) WO2013116296A1 (https=)

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KR20250099289A (ko) 2014-05-16 2025-07-01 아블린쓰 엔.브이. 개선된 면역글로불린 가변 도메인
PL3248986T3 (pl) 2014-05-16 2022-05-16 Ablynx Nv Domeny zmienne immunoglobuliny
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AU2019449475A1 (en) * 2019-06-04 2022-01-06 Shanghaitech University Affinity-maturated anti-ASIC1a antibodies
CN118955717A (zh) * 2019-07-11 2024-11-15 纪念斯隆凯特琳癌症中心 Dll3靶向抗体及其用途
AU2019457621A1 (en) * 2019-07-23 2022-02-17 Shanghaitech University ASIC1 channel antagonist antibody
JP7796008B2 (ja) * 2019-09-13 2026-01-08 メモリアル スローン ケタリング キャンサー センター 抗cd371抗体およびその使用
EP4384218A4 (en) * 2021-08-09 2025-11-05 Merck Patent Gmbh Proteins that uncouple T-lymphocyte-mediated tumor cytotoxicity from the release of pro-inflammatory cytokines
WO2023034566A1 (en) * 2021-09-02 2023-03-09 Memorial Sloan-Kettering Cancer Center Anti-dll3 antibodies and uses thereof
CN119331085B (zh) * 2024-10-16 2025-03-14 中国科学院合肥物质科学研究院 沙贝冠状病毒广谱中和抗体及其应用

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Also Published As

Publication number Publication date
CO7020877A2 (es) 2014-08-11
EA028647B1 (ru) 2017-12-29
DK2809681T3 (en) 2019-03-11
EP2809681A1 (en) 2014-12-10
ES2886123T3 (es) 2021-12-16
IN2014CN04645A (https=) 2015-09-18
SI2809681T1 (sl) 2019-04-30
AU2013215254B2 (en) 2017-08-31
MX2014008541A (es) 2014-10-24
KR20140125363A (ko) 2014-10-28
LT2809681T (lt) 2019-02-11
US9150648B2 (en) 2015-10-06
ES2707599T3 (es) 2019-04-04
EP3453723B1 (en) 2021-08-11
CN104093738B (zh) 2018-05-18
HRP20190358T1 (hr) 2019-04-05
SMT202100628T1 (it) 2022-01-10
PH12014501613A1 (en) 2014-10-13
PH12014501613B1 (en) 2014-10-13
JP6302844B2 (ja) 2018-03-28
DK3453723T3 (da) 2021-09-13
SG11201403222UA (en) 2014-07-30
US10513557B2 (en) 2019-12-24
BR112014018651A2 (pt) 2017-07-04
MY168748A (en) 2018-11-30
EP3453723A3 (en) 2019-04-10
US20180222976A1 (en) 2018-08-09
PL3453723T3 (pl) 2022-01-03
AU2013215254A1 (en) 2014-07-03
RS58439B1 (sr) 2019-04-30
HRP20211541T1 (hr) 2021-12-24
TWI591073B (zh) 2017-07-11
PT2809681T (pt) 2019-02-18
JP2015508063A (ja) 2015-03-16
HUE042531T2 (hu) 2019-07-29
EA201491452A1 (ru) 2014-11-28
CA2862332A1 (en) 2013-08-08
EP3453723A2 (en) 2019-03-13
IL233410A0 (en) 2014-08-31
SI3453723T1 (sl) 2021-11-30
PL2809681T3 (pl) 2019-05-31
HUE056335T2 (hu) 2022-02-28
IL254416A0 (en) 2017-11-30
AR089852A1 (es) 2014-09-24
US20130195878A1 (en) 2013-08-01
MX358518B (es) 2018-08-24
CA2862332C (en) 2021-05-18
EP2809681B1 (en) 2018-12-05
WO2013116296A1 (en) 2013-08-08
RS62454B1 (sr) 2021-11-30
CY1124778T1 (el) 2022-11-25
CY1121368T1 (el) 2020-05-29
CL2014002019A1 (es) 2015-01-16
KR102111941B1 (ko) 2020-05-18
PT3453723T (pt) 2021-09-07
IL254416B (en) 2018-03-29
UY34603A (es) 2013-07-31
LT3453723T (lt) 2021-09-10
TW201335182A (zh) 2013-09-01
CN104093738A (zh) 2014-10-08
US20160002332A1 (en) 2016-01-07
JO3547B1 (ar) 2020-07-05
HK1199269A1 (en) 2015-06-26

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