NZ594844A - Prion-specific peptoid reagents - Google Patents
Prion-specific peptoid reagentsInfo
- Publication number
- NZ594844A NZ594844A NZ594844A NZ59484406A NZ594844A NZ 594844 A NZ594844 A NZ 594844A NZ 594844 A NZ594844 A NZ 594844A NZ 59484406 A NZ59484406 A NZ 59484406A NZ 594844 A NZ594844 A NZ 594844A
- Authority
- NZ
- New Zealand
- Prior art keywords
- glycine
- sequence
- replaced
- substituted
- residues
- Prior art date
Links
- 108010043958 Peptoids Proteins 0.000 title abstract 5
- 102000029797 Prion Human genes 0.000 title abstract 2
- 108091000054 Prion Proteins 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 6
- 150000001413 amino acids Chemical class 0.000 abstract 5
- 239000004471 Glycine Substances 0.000 abstract 3
- 108010049175 N-substituted Glycines Proteins 0.000 abstract 3
- 125000003630 glycyl group Chemical class [H]N([H])C([H])([H])C(*)=O 0.000 abstract 3
- FOUZISDNESEYLX-UHFFFAOYSA-N 2-(2-hydroxyethylazaniumyl)acetate Chemical compound OCCNCC(O)=O FOUZISDNESEYLX-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 125000005647 linker group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000001717 pathogenic effect Effects 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 108010000652 (S)-N-(1-phenylethyl)glycine Proteins 0.000 abstract 1
- RHLQNMMWMDYKFY-UHFFFAOYSA-N 2-(2-methoxyethylazaniumyl)acetate Chemical compound COCCNCC(O)=O RHLQNMMWMDYKFY-UHFFFAOYSA-N 0.000 abstract 1
- OGAULEBSQQMUKP-UHFFFAOYSA-N 2-(4-aminobutylamino)acetic acid Chemical compound NCCCCNCC(O)=O OGAULEBSQQMUKP-UHFFFAOYSA-N 0.000 abstract 1
- KGSVNOLLROCJQM-UHFFFAOYSA-N 2-(benzylamino)acetic acid Chemical compound OC(=O)CNCC1=CC=CC=C1 KGSVNOLLROCJQM-UHFFFAOYSA-N 0.000 abstract 1
- GYOOOIWLBRGIME-UHFFFAOYSA-N 2-[2-(4-methoxyphenyl)ethylazaniumyl]acetate Chemical compound COC1=CC=C(CCNCC(O)=O)C=C1 GYOOOIWLBRGIME-UHFFFAOYSA-N 0.000 abstract 1
- RFEBVEWGRABHPU-QMMMGPOBSA-N 2-[[(1s)-1-phenylethyl]azaniumyl]acetate Chemical group OC(=O)CN[C@@H](C)C1=CC=CC=C1 RFEBVEWGRABHPU-QMMMGPOBSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 125000000592 heterocycloalkyl group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71576105P | 2005-09-09 | 2005-09-09 | |
| US72668605P | 2005-10-14 | 2005-10-14 | |
| US75893406P | 2006-01-13 | 2006-01-13 | |
| PCT/US2006/035226 WO2007030804A1 (en) | 2005-09-09 | 2006-09-08 | Prion-specific peptoid reagents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ594844A true NZ594844A (en) | 2013-04-26 |
Family
ID=37651167
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ594844A NZ594844A (en) | 2005-09-09 | 2006-09-08 | Prion-specific peptoid reagents |
| NZ566020A NZ566020A (en) | 2005-09-09 | 2006-09-08 | Prion-specific peptoid reagents |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ566020A NZ566020A (en) | 2005-09-09 | 2006-09-08 | Prion-specific peptoid reagents |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7834144B2 (enExample) |
| EP (2) | EP2383281A3 (enExample) |
| JP (2) | JP5209477B2 (enExample) |
| KR (1) | KR20080048527A (enExample) |
| CN (1) | CN101356186A (enExample) |
| AU (1) | AU2006287299B2 (enExample) |
| BR (1) | BRPI0615618A2 (enExample) |
| CA (1) | CA2621767A1 (enExample) |
| DK (1) | DK1931695T3 (enExample) |
| ES (1) | ES2404940T3 (enExample) |
| IL (1) | IL189992A0 (enExample) |
| NZ (2) | NZ594844A (enExample) |
| WO (1) | WO2007030804A1 (enExample) |
| ZA (1) | ZA200802186B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060035242A1 (en) * | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
| WO2006076497A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Osplation of pathogenic prions |
| WO2006076683A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Isolation and detection of pathogenic prions |
| US7834144B2 (en) | 2005-09-09 | 2010-11-16 | Novartis Ag | Prion-specific peptoid reagents |
| FR2892820B1 (fr) * | 2005-11-03 | 2008-02-01 | Diagast Soc Par Actions Simpli | Procede magnetique d'immunodiagnostic pour la mise en evidence de complexe anticorps/antigene, en particulier de groupe sanguin |
| US9260476B2 (en) | 2007-02-23 | 2016-02-16 | The Research Foundation For The State University Of New York | RNA targeting compounds and methods for making and using same |
| US9150612B2 (en) * | 2007-02-23 | 2015-10-06 | The Research Foundation Of State University Of New York | RNA targeting compounds and methods for making and using same |
| CA2684798A1 (en) * | 2007-04-04 | 2008-10-16 | Novartis Ag | Prion elisa |
| WO2008124098A1 (en) * | 2007-04-04 | 2008-10-16 | Novartis Ag | Prion assay |
| CA2696417A1 (en) * | 2007-10-02 | 2009-04-09 | Csl Limited | Therapeutic antibody purification method and method of use |
| JP2011511077A (ja) * | 2008-02-08 | 2011-04-07 | ノースウエスタン ユニバーシティ | 選択的ポリ−n−置換グリシン抗生物質 |
| AU2009243060A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag. | Assay for pathogenic conformers |
| WO2010017412A1 (en) * | 2008-08-06 | 2010-02-11 | The Regents Of The University Of California | Novel biomimetic peptoid polymers |
| EP2401264A4 (en) * | 2009-02-24 | 2013-08-07 | Univ New York | PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR THEIR USE |
| AU2010256880B2 (en) | 2009-06-02 | 2015-01-22 | Opko Health, Inc. | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases |
| WO2011057029A1 (en) * | 2009-11-04 | 2011-05-12 | Novartis Ag | Positively charged species as binding reagents in the separation of protein aggregates from monomers |
| US8952127B2 (en) | 2010-06-04 | 2015-02-10 | The Regents Of The University Of California | Peptoids useful for catalyzing the mineralization of calcium carbonate |
| WO2013043669A1 (en) * | 2011-09-21 | 2013-03-28 | The Board Of Regents Of The University Of Texas System | Peptoid compositions for the treatment of alzheimer's disease and polyglutamine expansion disorder |
| WO2014025785A2 (en) * | 2012-08-06 | 2014-02-13 | Trustees Of Boston University | Prion protein ligands as therapeutic agents for neurodegenerative disorders |
| US9764953B2 (en) | 2013-03-20 | 2017-09-19 | The Regents Of The University Of California | Peptoids useful for the mineralization of apatite |
| WO2016145286A1 (en) * | 2015-03-11 | 2016-09-15 | Lumos Pharma, Inc. | Synthesis of cyclocreatine and analogs thereof |
| CA3001065A1 (en) | 2015-10-14 | 2017-04-20 | Xiaoxi WEI | Compositions and methods for reducing ice crystal formation |
| EP3426673B1 (en) * | 2016-03-09 | 2021-05-05 | Mike-Ann, LLC | Peptoid affinity ligands |
| JP7212373B2 (ja) * | 2017-04-12 | 2023-01-25 | エックス-サーマ インコーポレイテッド | 新規ペプトイドポリマーおよび使用方法 |
| JP7495934B2 (ja) | 2018-12-10 | 2024-06-05 | プロビビ インコーポレイテッド | 共役ジエンフェロモンおよび関連化合物の合成方法 |
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| US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
| JP3910569B2 (ja) | 2003-08-19 | 2007-04-25 | 独立行政法人科学技術振興機構 | アミロイドβ蛋白質のアミロイド線維化を増幅するための試薬 |
| WO2005060697A2 (en) * | 2003-12-19 | 2005-07-07 | Chiron Corporation | Cell transfecting formulations of small interfering rna, related compositions and methods of making and use |
| SE0400274D0 (sv) | 2004-02-09 | 2004-02-09 | Affibody Ab | New polypeptide |
| JP4773697B2 (ja) | 2004-06-30 | 2011-09-14 | ルネサスエレクトロニクス株式会社 | Soi基板およびその製造方法ならびに半導体装置 |
| DE102004043782A1 (de) | 2004-09-08 | 2006-03-09 | Heinrich-Heine-Universität Düsseldorf | Polypeptide und Verfahren zur spezifischen Bindung von Prionen |
| US20060057671A1 (en) | 2004-09-10 | 2006-03-16 | Orser Cindy S | Immobilized probes and methods of detecting conformationally altered prion proteins |
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| AU2005209592B2 (en) | 2004-09-30 | 2012-07-12 | Ortho-Clinical Diagnostics, Inc. | Peptides for discrimination of prions |
| JP5162250B2 (ja) | 2005-01-13 | 2013-03-13 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | プリオン特異的ペプチド試薬を使用するelisaアッセイ |
| WO2006076497A2 (en) | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Osplation of pathogenic prions |
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| GB0503434D0 (en) | 2005-02-18 | 2005-03-30 | Senexis Ltd | Amyloid-binding peptides, analogues and uses thereof |
| US7834144B2 (en) | 2005-09-09 | 2010-11-16 | Novartis Ag | Prion-specific peptoid reagents |
| WO2007145589A1 (en) | 2006-06-15 | 2007-12-21 | Per Arvidsson | Peptides that are capable of binding to amyloid-beta peptide. |
| CN101802609A (zh) | 2006-07-28 | 2010-08-11 | 阿德利夫股份有限公司 | 用于诊断和治疗的肽探针 |
| US9217036B2 (en) | 2007-04-26 | 2015-12-22 | Yale University | Prion protein as a receptor for amyloid-β oligomers |
-
2006
- 2006-09-08 US US11/518,091 patent/US7834144B2/en not_active Expired - Fee Related
- 2006-09-08 AU AU2006287299A patent/AU2006287299B2/en not_active Ceased
- 2006-09-08 DK DK06814415.3T patent/DK1931695T3/da active
- 2006-09-08 ES ES06814415T patent/ES2404940T3/es active Active
- 2006-09-08 BR BRPI0615618-5A patent/BRPI0615618A2/pt not_active IP Right Cessation
- 2006-09-08 EP EP20110171585 patent/EP2383281A3/en not_active Withdrawn
- 2006-09-08 NZ NZ594844A patent/NZ594844A/xx not_active IP Right Cessation
- 2006-09-08 WO PCT/US2006/035226 patent/WO2007030804A1/en not_active Ceased
- 2006-09-08 NZ NZ566020A patent/NZ566020A/xx not_active IP Right Cessation
- 2006-09-08 JP JP2008530008A patent/JP5209477B2/ja not_active Expired - Fee Related
- 2006-09-08 KR KR1020087008427A patent/KR20080048527A/ko not_active Abandoned
- 2006-09-08 CA CA002621767A patent/CA2621767A1/en not_active Abandoned
- 2006-09-08 EP EP06814415.3A patent/EP1931695B1/en not_active Not-in-force
- 2006-09-08 CN CNA2006800331296A patent/CN101356186A/zh active Pending
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2008
- 2008-03-06 IL IL189992A patent/IL189992A0/en unknown
- 2008-03-07 ZA ZA200802186A patent/ZA200802186B/xx unknown
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2010
- 2010-10-07 US US12/924,872 patent/US20120027677A1/en not_active Abandoned
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2012
- 2012-06-01 JP JP2012126346A patent/JP2012162571A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009507833A (ja) | 2009-02-26 |
| IL189992A0 (en) | 2008-08-07 |
| AU2006287299B2 (en) | 2012-08-23 |
| EP1931695A1 (en) | 2008-06-18 |
| ES2404940T3 (es) | 2013-05-29 |
| BRPI0615618A2 (pt) | 2011-05-24 |
| ZA200802186B (en) | 2008-12-31 |
| JP2012162571A (ja) | 2012-08-30 |
| EP1931695B1 (en) | 2013-04-10 |
| US20120027677A1 (en) | 2012-02-02 |
| KR20080048527A (ko) | 2008-06-02 |
| EP2383281A3 (en) | 2012-01-04 |
| AU2006287299A1 (en) | 2007-03-15 |
| DK1931695T3 (da) | 2013-07-01 |
| NZ566020A (en) | 2012-08-31 |
| CA2621767A1 (en) | 2007-03-15 |
| EP2383281A2 (en) | 2011-11-02 |
| US7834144B2 (en) | 2010-11-16 |
| CN101356186A (zh) | 2009-01-28 |
| US20070087972A1 (en) | 2007-04-19 |
| JP5209477B2 (ja) | 2013-06-12 |
| WO2007030804A1 (en) | 2007-03-15 |
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