NZ591142A - Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide - Google Patents
Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamideInfo
- Publication number
- NZ591142A NZ591142A NZ591142A NZ59114206A NZ591142A NZ 591142 A NZ591142 A NZ 591142A NZ 591142 A NZ591142 A NZ 591142A NZ 59114206 A NZ59114206 A NZ 59114206A NZ 591142 A NZ591142 A NZ 591142A
- Authority
- NZ
- New Zealand
- Prior art keywords
- methyl
- salts
- ylamino
- imidazol
- pyrimidin
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- HHZIURLSWUIHRB-UHFFFAOYSA-N nilotinib Chemical class C1=NC(C)=CN1C1=CC(NC(=O)C=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)=CC(C(F)(F)F)=C1 HHZIURLSWUIHRB-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- SRSXLGNVWSONIS-UHFFFAOYSA-M benzenesulfonate Chemical compound [O-]S(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-M 0.000 abstract 1
- 229940077388 benzenesulfonate Drugs 0.000 abstract 1
- 239000001177 diphosphate Substances 0.000 abstract 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 1
- 235000011180 diphosphates Nutrition 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 150000004712 monophosphates Chemical class 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical class CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70140605P | 2005-07-20 | 2005-07-20 | |
| US71621305P | 2005-09-12 | 2005-09-12 | |
| NZ564182A NZ564182A (en) | 2005-07-20 | 2006-07-18 | Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ591142A true NZ591142A (en) | 2012-09-28 |
Family
ID=37398525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ591142A NZ591142A (en) | 2005-07-20 | 2006-07-18 | Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide |
| NZ564182A NZ564182A (en) | 2005-07-20 | 2006-07-18 | Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ564182A NZ564182A (en) | 2005-07-20 | 2006-07-18 | Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide |
Country Status (34)
| Country | Link |
|---|---|
| US (4) | US8163904B2 (ru) |
| EP (2) | EP2186808B1 (ru) |
| JP (1) | JP5129132B2 (ru) |
| KR (3) | KR101755137B1 (ru) |
| CN (1) | CN102267981A (ru) |
| AR (1) | AR057467A1 (ru) |
| AT (1) | ATE514689T1 (ru) |
| AU (2) | AU2006276205C1 (ru) |
| BR (1) | BRPI0613605A2 (ru) |
| CA (2) | CA2615669C (ru) |
| CY (1) | CY1111772T1 (ru) |
| DK (1) | DK1910336T3 (ru) |
| EC (1) | ECSP088118A (ru) |
| ES (1) | ES2634291T3 (ru) |
| GT (1) | GT200600316A (ru) |
| HK (1) | HK1116778A1 (ru) |
| HR (1) | HRP20110639T1 (ru) |
| IL (1) | IL187787A (ru) |
| JO (1) | JO2757B1 (ru) |
| MA (1) | MA29686B1 (ru) |
| MX (1) | MX2008000892A (ru) |
| MY (1) | MY149889A (ru) |
| NO (1) | NO341313B1 (ru) |
| NZ (2) | NZ591142A (ru) |
| PE (1) | PE20070241A1 (ru) |
| PL (1) | PL1910336T3 (ru) |
| PT (1) | PT1910336E (ru) |
| RU (4) | RU2483065C2 (ru) |
| SG (1) | SG170772A1 (ru) |
| SI (1) | SI1910336T1 (ru) |
| TN (1) | TNSN08028A1 (ru) |
| TW (1) | TWI455934B (ru) |
| UY (1) | UY29683A1 (ru) |
| WO (1) | WO2007015871A1 (ru) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200600316A (es) * | 2005-07-20 | 2007-04-02 | Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida. | |
| GT200600315A (es) | 2005-07-20 | 2007-03-19 | Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida | |
| KR20090031855A (ko) * | 2006-04-07 | 2009-03-30 | 노파르티스 아게 | 백혈병의 치료를 위한, 피리미딜아미노벤즈아미드 화합물과조합된 ｃ-ｓｒｃ 억제제의 용도 |
| EP1923053A1 (en) | 2006-09-27 | 2008-05-21 | Novartis AG | Pharmaceutical compositions comprising nilotinib or its salt |
| US20100016590A1 (en) | 2008-07-17 | 2010-01-21 | Teva Pharmaceutical Industries Ltd. | Nilotinib intermediates and preparation thereof |
| KR101251726B1 (ko) | 2008-11-05 | 2013-04-05 | 테바 파마슈티컬 인더스트리즈 리미티드 | 닐로티닙 ＨＣｌ 결정형 |
| EP2186514B1 (en) * | 2008-11-14 | 2016-06-29 | Kinki University | Treatment of Malignant Peripheral Nerve Sheath Tumors |
| BRPI1013366A2 (pt) | 2009-03-06 | 2016-03-29 | Novartis Ag | uso de derivados de pirimidilaminobenzamida para o tratamento de distúrbios mediados pela quinase contendo zíper de leucina e quinase contendo motivo alfa estéril (zak). |
| TW201102068A (en) | 2009-06-02 | 2011-01-16 | Novartis Ag | Treatment of ophthalmologic disorders mediated by alpha-carbonic anhydrase isoforms |
| US20110053968A1 (en) | 2009-06-09 | 2011-03-03 | Auspex Pharmaceuticals, Inc. | Aminopyrimidine inhibitors of tyrosine kinase |
| WO2011033307A1 (en) | 2009-09-17 | 2011-03-24 | Generics [Uk] Limited | Nilotinib dihydrochloride salt |
| MX2012004709A (es) | 2009-10-23 | 2012-05-23 | Novartis Ag | Metodo para el tratamiento de transtornos proliferativos y otras condiciones patologicas mediadas por la actividad de cinasa de bcr-abl, c-kit, ddr1, ddr2 o pdgf-r. |
| JO3634B1 (ar) | 2009-11-17 | 2020-08-27 | Novartis Ag | طريقة لعلاج اضطرابات تكاثرية وحالات مرضية أخرى متوسطة بنشاط كيناز bcr-abl، c-kit، ddr1، ddr2، أو pdgf-r |
| IN2010KO00035A (ru) | 2010-01-15 | 2016-09-02 | ||
| JP2013525296A (ja) | 2010-04-16 | 2013-06-20 | ノバルティス アーゲー | 内分泌療法抵抗性乳癌の処置 |
| EP2382976A1 (en) | 2010-04-30 | 2011-11-02 | Hiroshima University | Use of pdgf-r inhibitors for the treatment of lymph node metastasis of gastric cancer |
| US8937082B2 (en) | 2010-06-21 | 2015-01-20 | Teva Pharmaceutical Industries Ltd. | Nilotinib salts and crystalline forms thereof |
| WO2012014127A1 (en) | 2010-07-30 | 2012-02-02 | Ranbaxy Laboratories Limited | 5-lipoxygenase inhibitors |
| CN102453024B (zh) * | 2010-10-27 | 2014-09-03 | 浙江九洲药业股份有限公司 | 一种尼罗替尼盐酸盐晶型及其制备方法 |
| US8703788B2 (en) * | 2010-11-26 | 2014-04-22 | Bandi Parthasaradhi Reddy | Polymorph of nilotinib hydrochloride |
| AR086913A1 (es) | 2011-06-14 | 2014-01-29 | Novartis Ag | 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]-amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluoro-metil)-fenil]-benzamida amorfa, forma de dosificacion que la contiene y metodo para prepararlas |
| CA2853095A1 (en) | 2011-10-28 | 2013-05-02 | Novartis Ag | Method of treating gastrointestinal stromal tumors |
| WO2013063003A1 (en) | 2011-10-28 | 2013-05-02 | Novartis Ag | Method of treating gastrointestinal stromal tumors |
| WO2013074432A1 (en) | 2011-11-14 | 2013-05-23 | Novartis Ag | Immediate release 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-n-[5-(4-methyl- 1h-imidazol-1-yl)-3-(trifluoromethyl)phenyl] benzamide formulation |
| IN2014DN10801A (ru) | 2012-07-11 | 2015-09-04 | Novartis Ag | |
| CA2888002A1 (en) | 2012-10-15 | 2014-04-24 | Apotex Inc. | Solid forms of nilotinib hydrochloride |
| CA2887540A1 (en) * | 2012-10-19 | 2014-04-24 | Basf Se | Multicomponent crystalline system comprising nilotinib and selected co-crystal formers |
| EP2792360A1 (en) | 2013-04-18 | 2014-10-22 | IP Gesellschaft für Management mbH | (1aR,12bS)-8-cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide for use in treating HCV |
| EP2989090A4 (en) | 2013-04-24 | 2017-01-18 | Dr. Reddy's Laboratories Ltd. | Polymorphic forms of nilotinib hydrochloride |
| RU2551359C9 (ru) * | 2013-11-28 | 2021-08-20 | Общество с ограниченной ответственностью "Мамонт Фарм" | Наноразмерная слабо закристаллизованная модификация 4-метил-N-[3-(4-метилимидазол-1-ил)-5-(трифторметил)фенил]-3-[(4-пиридин-3-илпиримидин-2-ил)амино]бензамида гидрохлорида моногидрата, способ ее получения и фармацевтическая композиция на ее основе |
| WO2015092624A1 (en) | 2013-12-16 | 2015-06-25 | Ranbaxy Laboratories Limited | Nilotinib mono-oxalate and its crystalline form |
| US9926296B2 (en) | 2014-08-08 | 2018-03-27 | Dr. Reddy's Laboratories Limited | Process for the preparation of polymorphic forms of nilotinib hydrochloride |
| US10138221B2 (en) * | 2014-08-11 | 2018-11-27 | Sun Pharmaceutical Industries Limited | Salts of nilotinib and polymorphs thereof |
| WO2016151304A1 (en) | 2015-03-20 | 2016-09-29 | Cipla Limited | Novel polymorphic form x of nilotinib dihydrochloride hydrate |
| EP3408264B1 (en) | 2016-01-26 | 2020-03-11 | Farma GRS, d.o.o. | Nilotinib dinitrate (v) and crystalline forms thereof |
| WO2017149550A1 (en) * | 2016-03-02 | 2017-09-08 | Msn Laboratories Private Limited | Amorphous form of 4-methyl-n-[3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzamide |
| EP3430004B1 (en) | 2016-03-14 | 2020-07-15 | Pliva Hrvatska D.O.O. | Solid state forms of nilotinib salts |
| EP3404025B1 (en) * | 2017-05-16 | 2019-12-04 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of pure nilotinib and its salt |
| CZ2017821A3 (cs) | 2017-12-20 | 2019-07-03 | Zentiva, K.S. | Léková forma obsahující krystalický nilotinib |
| CN116808044A (zh) | 2018-06-15 | 2023-09-29 | 汉达癌症医药责任有限公司 | 激酶抑制剂的盐类及其组合物 |
| WO2020095187A1 (en) * | 2018-11-05 | 2020-05-14 | Laurus Labs Limited | Crystalline form of nilotinib hydrochloride, process for its preparation and pharmaceutical composition containing the same |
| US10874671B2 (en) * | 2019-02-18 | 2020-12-29 | Slayback Pharma Llc | Pharmaceutical compositions of nilotinib |
| IL295007A (en) | 2020-01-31 | 2022-09-01 | Nanocopoeia Llc | Amorphous nilotinib microparticles and uses thereof |
| WO2021161347A1 (en) | 2020-02-15 | 2021-08-19 | Cipla Limited | Novel salts of nilotinib and polymorphic forms thereof |
| CA3181361A1 (en) | 2020-04-30 | 2021-11-04 | Nanocopoeia, Llc | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
| CN114133378B (zh) * | 2020-09-04 | 2023-08-15 | 成都苑东生物制药股份有限公司 | 一种盐酸尼洛替尼共晶及其制备方法 |
| EP4260848A1 (en) | 2022-04-11 | 2023-10-18 | Lotus Pharmaceutical Co., Ltd. | Pharmaceutical composition for solid dosage form containing nilotinib and process for its preparation |
| WO2024142002A1 (en) | 2022-12-29 | 2024-07-04 | Renata Pharmaceuticals (Ireland) Limited | Pharmaceutical suspension of nilotinib |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2081108C1 (ru) * | 1991-10-16 | 1997-06-10 | Циба-Гейги АГ | Аддитивные соли кислот с основанием и фармацевтическая композиция, обладающая противоопухолевой активностью |
| US5516775A (en) | 1992-08-31 | 1996-05-14 | Ciba-Geigy Corporation | Further use of pyrimidine derivatives |
| ATE208772T1 (de) | 1993-10-01 | 2001-11-15 | Novartis Erfind Verwalt Gmbh | Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung |
| CO4940418A1 (es) * | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| KR20020060998A (ko) * | 1999-12-14 | 2002-07-19 | 니뽄 신야쿠 가부시키가이샤 | 복소환 유도체 및 의약 |
| GB0215676D0 (en) | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| GB2398565A (en) * | 2003-02-18 | 2004-08-25 | Cipla Ltd | Imatinib preparation and salts |
| MY144177A (en) | 2004-02-04 | 2011-08-15 | Novartis Ag | Salt forms of 4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide. |
| SA06270147B1 (ar) * | 2005-06-09 | 2009-12-22 | نوفارتيس ايه جي | عملية لتخليق 5-(مثيل–1h–إيميدازول–1-يل )–3-(ثلاثي فلـورو مثيل)–بنزامـين |
| GT200600315A (es) | 2005-07-20 | 2007-03-19 | Formas cristalinas de 4-metilo-n-[3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo]-3-(4-pyridina-3-ilo-pirimidina-2-iloamino)-benzamida | |
| GT200600316A (es) * | 2005-07-20 | 2007-04-02 | Sales de 4-metilo-n-(3-(4-metilo-imidazol-1-ilo)-5-trifluorometilo-fenilo)-3-(4-piridina-3-ilo-pirimidina-2-iloamino)- benzamida. |
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2006
- 2006-07-14 GT GT200600316A patent/GT200600316A/es unknown
- 2006-07-18 AU AU2006276205A patent/AU2006276205C1/en active Active
- 2006-07-18 CN CN2011102503529A patent/CN102267981A/zh active Pending
- 2006-07-18 US US11/995,898 patent/US8163904B2/en active Active
- 2006-07-18 AT AT06787733T patent/ATE514689T1/de active
- 2006-07-18 SI SI200631100T patent/SI1910336T1/sl unknown
- 2006-07-18 NZ NZ591142A patent/NZ591142A/xx unknown
- 2006-07-18 MY MYPI20063405A patent/MY149889A/en unknown
- 2006-07-18 EP EP10150322.5A patent/EP2186808B1/en active Active
- 2006-07-18 AR ARP060103071A patent/AR057467A1/es unknown
- 2006-07-18 CA CA2615669A patent/CA2615669C/en active Active
- 2006-07-18 CA CA2823946A patent/CA2823946C/en active Active
- 2006-07-18 PL PL06787733T patent/PL1910336T3/pl unknown
- 2006-07-18 DK DK06787733.2T patent/DK1910336T3/da active
- 2006-07-18 KR KR1020157022022A patent/KR101755137B1/ko active IP Right Grant
- 2006-07-18 SG SG201102150-8A patent/SG170772A1/en unknown
- 2006-07-18 MX MX2008000892A patent/MX2008000892A/es active IP Right Grant
- 2006-07-18 WO PCT/US2006/027878 patent/WO2007015871A1/en active Application Filing
- 2006-07-18 JP JP2008522900A patent/JP5129132B2/ja active Active
- 2006-07-18 PT PT06787733T patent/PT1910336E/pt unknown
- 2006-07-18 RU RU2011120363/04A patent/RU2483065C2/ru active
- 2006-07-18 RU RU2008105827/04A patent/RU2434864C2/ru active
- 2006-07-18 RU RU2012143989/04A patent/RU2509767C1/ru active
- 2006-07-18 EP EP06787733A patent/EP1910336B1/en active Active
- 2006-07-18 KR KR1020147007695A patent/KR20140047737A/ko not_active Application Discontinuation
- 2006-07-18 NZ NZ564182A patent/NZ564182A/en unknown
- 2006-07-18 ES ES10150322.5T patent/ES2634291T3/es active Active
- 2006-07-18 BR BRPI0613605-2A patent/BRPI0613605A2/pt not_active Application Discontinuation
- 2006-07-18 KR KR1020087001461A patent/KR20080027855A/ko not_active Application Discontinuation
- 2006-07-19 TW TW095126416A patent/TWI455934B/zh active
- 2006-07-20 PE PE2006000874A patent/PE20070241A1/es active IP Right Grant
- 2006-07-20 UY UY29683A patent/UY29683A1/es not_active Application Discontinuation
- 2006-07-20 JO JO2006242A patent/JO2757B1/en active
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2007
- 2007-11-29 IL IL187787A patent/IL187787A/en active IP Right Grant
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2008
- 2008-01-09 MA MA30563A patent/MA29686B1/fr unknown
- 2008-01-18 TN TNP2008000028A patent/TNSN08028A1/en unknown
- 2008-01-18 EC EC2008008118A patent/ECSP088118A/es unknown
- 2008-02-20 NO NO20080897A patent/NO341313B1/no unknown
- 2008-07-08 HK HK08107504.6A patent/HK1116778A1/xx unknown
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2010
- 2010-11-12 AU AU2010241419A patent/AU2010241419C1/en active Active
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2011
- 2011-08-26 CY CY20111100813T patent/CY1111772T1/el unknown
- 2011-09-07 HR HR20110639T patent/HRP20110639T1/hr unknown
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2012
- 2012-03-13 US US13/419,132 patent/US8389537B2/en active Active
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2013
- 2013-01-15 RU RU2013101749/04A patent/RU2605551C2/ru active
- 2013-01-22 US US13/747,052 patent/US8580806B2/en active Active
- 2013-10-11 US US14/051,725 patent/US9163005B2/en active Active
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