NZ586939A - Cpmv rna-2 genome segment derived protein expression systems - Google Patents
Cpmv rna-2 genome segment derived protein expression systemsInfo
- Publication number
- NZ586939A NZ586939A NZ586939A NZ58693909A NZ586939A NZ 586939 A NZ586939 A NZ 586939A NZ 586939 A NZ586939 A NZ 586939A NZ 58693909 A NZ58693909 A NZ 58693909A NZ 586939 A NZ586939 A NZ 586939A
- Authority
- NZ
- New Zealand
- Prior art keywords
- rna
- expression system
- expression
- genome segment
- protein expression
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 241000723655 Cowpea mosaic virus Species 0.000 abstract 2
- 108700028146 Genetic Enhancer Elements Proteins 0.000 abstract 2
- 230000000977 initiatory effect Effects 0.000 abstract 2
- 108020005345 3' Untranslated Regions Proteins 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241000961587 Secoviridae Species 0.000 abstract 1
- 108091081024 Start codon Proteins 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 230000017074 necrotic cell death Effects 0.000 abstract 1
- 230000029812 viral genome replication Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0800272.7A GB0800272D0 (en) | 2008-01-08 | 2008-01-08 | Protein expression systems |
| PCT/GB2009/000060 WO2009087391A1 (en) | 2008-01-08 | 2009-01-08 | Protein expression systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ586939A true NZ586939A (en) | 2012-08-31 |
Family
ID=39111256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ586939A NZ586939A (en) | 2008-01-08 | 2009-01-08 | Cpmv rna-2 genome segment derived protein expression systems |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US8674084B2 (https=) |
| EP (1) | EP2240589B1 (https=) |
| JP (1) | JP5745857B2 (https=) |
| KR (1) | KR101602972B1 (https=) |
| CN (1) | CN101952446B (https=) |
| AU (1) | AU2009203608B2 (https=) |
| BR (1) | BRPI0906509A2 (https=) |
| CA (1) | CA2711895C (https=) |
| DK (1) | DK2240589T3 (https=) |
| ES (1) | ES2537198T3 (https=) |
| GB (1) | GB0800272D0 (https=) |
| IL (1) | IL206606A (https=) |
| MX (1) | MX2010007336A (https=) |
| NZ (1) | NZ586939A (https=) |
| PT (1) | PT2240589E (https=) |
| RU (1) | RU2539793C2 (https=) |
| WO (1) | WO2009087391A1 (https=) |
| ZA (1) | ZA201005245B (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| WO2009076778A1 (en) | 2007-11-27 | 2009-06-25 | Medicago Inc. | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| AU2009267769B2 (en) | 2008-07-08 | 2015-07-16 | Medicago Inc. | Soluble recombinant influenza antigens |
| HUE039100T2 (hu) | 2009-06-24 | 2018-12-28 | Medicago Inc | Hemagglutinint tartalmazó kimer influenzavírus-jellegû részecskék |
| GB201002434D0 (en) * | 2010-02-12 | 2010-03-31 | Plant Bioscience Ltd | Non-infectious RNA source |
| WO2012058762A1 (en) | 2010-11-04 | 2012-05-10 | Medicago Inc. | Plant expression system |
| PT2665818T (pt) | 2011-01-17 | 2017-07-05 | Philip Morris Products Sa | Expressão de proteínas em plantas |
| CA2824155A1 (en) | 2011-01-17 | 2012-07-26 | Philip Morris Products S.A. | Vectors for nucleic acid expression in plants |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| NZ622731A (en) | 2011-09-30 | 2016-04-29 | Medicago Inc | Increasing virus-like particle yield in plants |
| BR112014011345A2 (pt) * | 2011-11-11 | 2017-05-16 | Philip Morris Products Sa | partículas tipo vírus da influenza (vlps) compreendendo nicotiana tabacum produzida por hemaglutinina |
| JP2015528285A (ja) * | 2012-09-05 | 2015-09-28 | メディカゴ インコーポレイテッド | 植物におけるピコルナウイルス様粒子の産生 |
| KR101449155B1 (ko) * | 2012-12-06 | 2014-10-13 | 주식회사 바이오앱 | 식물체에서 목적 단백질의 번역 효율을 증진시키기 위한 염기서열 |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| ES2803508T3 (es) | 2013-03-28 | 2021-01-27 | Medicago Inc | Producción de partículas similares al virus de la gripe en plantas |
| RU2699982C2 (ru) * | 2014-01-10 | 2019-09-11 | Медикаго Инк. | Энхансерные элементы cpmv |
| US10563213B2 (en) | 2014-03-27 | 2020-02-18 | Medicago Inc. | Modified CPMV enhancer elements |
| RU2731295C2 (ru) | 2014-07-11 | 2020-09-01 | Медикаго Инк. | Модификация продуцирования белков в растениях |
| AU2016208999A1 (en) | 2015-01-23 | 2017-07-13 | Medicago Inc. | Rotavirus-like particle production in plants |
| JP2018524345A (ja) | 2015-07-02 | 2018-08-30 | メディカゴ インコーポレイテッド | ジャスモン酸経路アクチベーター |
| CN110506118A (zh) * | 2017-02-02 | 2019-11-26 | 杜克大学 | 用于控制基因表达的组合物和方法 |
| GB201721600D0 (en) | 2017-12-21 | 2018-02-07 | Plant Bioscience Ltd | Metabolic engineering |
| CN112400021A (zh) | 2018-03-14 | 2021-02-23 | 麦迪卡格公司 | 植物表达增强子 |
| GB201808617D0 (en) | 2018-05-25 | 2018-07-11 | Plant Bioscience Ltd | Scaffold modification |
| WO2020033416A1 (en) * | 2018-08-06 | 2020-02-13 | Northwestern University | Combined transcription and translation platform derived from plant chloroplasts |
| WO2020181354A1 (en) | 2019-03-14 | 2020-09-17 | Mitsubishi Tanabe Pharma Corporation | Endogenous plant expression enhancer |
| GB201908431D0 (en) | 2019-06-12 | 2019-07-24 | Plant Bioscience Ltd | Biosynthetic genes and polypeptides |
| CN114040979B (zh) * | 2019-06-21 | 2024-06-28 | 国立大学法人大阪大学 | 稳定地保持外源基因的人工重组rna病毒的制作方法 |
| GB201909104D0 (en) | 2019-06-25 | 2019-08-07 | Plant Bioscience Ltd | Transferase enzymes |
| CN110468129B (zh) * | 2019-08-08 | 2023-03-24 | 四川农业大学 | 一种基于cmv rna2的体外干扰黄瓜花叶病的制剂、其制备方法与应用 |
| CN111777670B (zh) * | 2020-06-19 | 2021-07-30 | 东北农业大学 | 一种pH调节自组装抗菌肽及制备方法和应用 |
| WO2022260849A1 (en) | 2021-06-09 | 2022-12-15 | Nant Holdings Ip, Llc | Methods and systems for producing a protein of interest in a plant |
| CN114181969B (zh) * | 2021-12-09 | 2024-05-28 | 苏州大学 | 一种制备包裹外源蛋白的多角体的方法 |
| GB202209501D0 (en) | 2022-06-29 | 2022-08-10 | Plant Bioscience Ltd | Biosynthetic enzymes |
| CN121195070A (zh) | 2023-04-03 | 2025-12-23 | 斯威夫特制药有限责任公司 | 用于在植物中高效异源基因表达的反式互补载体系统 |
| KR20250082120A (ko) * | 2023-11-29 | 2025-06-09 | 서강대학교산학협력단 | 검은눈콩 모자이크 바이러스의 바이러스 유사 입자의 제조방법 및 이의 활용 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19701141C1 (de) * | 1997-01-16 | 1998-04-09 | Hoechst Ag | Genkonstrukte für durch Proteasen aktivierbare Wirksubstanzen |
| AU7373801A (en) * | 2000-06-13 | 2001-12-24 | Univ Queensland | Expression modulating sequences |
| CA2651907C (en) * | 2006-05-22 | 2016-12-20 | Plant Bioscience Limited | Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| RU2699982C2 (ru) | 2014-01-10 | 2019-09-11 | Медикаго Инк. | Энхансерные элементы cpmv |
| US10563213B2 (en) | 2014-03-27 | 2020-02-18 | Medicago Inc. | Modified CPMV enhancer elements |
-
2008
- 2008-01-08 GB GBGB0800272.7A patent/GB0800272D0/en not_active Ceased
-
2009
- 2009-01-08 PT PT97006498T patent/PT2240589E/pt unknown
- 2009-01-08 EP EP09700649.8A patent/EP2240589B1/en active Active
- 2009-01-08 BR BRPI0906509A patent/BRPI0906509A2/pt not_active Application Discontinuation
- 2009-01-08 JP JP2010541103A patent/JP5745857B2/ja not_active Expired - Fee Related
- 2009-01-08 CN CN200980105869.XA patent/CN101952446B/zh not_active Expired - Fee Related
- 2009-01-08 CA CA2711895A patent/CA2711895C/en active Active
- 2009-01-08 MX MX2010007336A patent/MX2010007336A/es active IP Right Grant
- 2009-01-08 WO PCT/GB2009/000060 patent/WO2009087391A1/en not_active Ceased
- 2009-01-08 DK DK09700649T patent/DK2240589T3/en active
- 2009-01-08 KR KR1020107017609A patent/KR101602972B1/ko not_active Expired - Fee Related
- 2009-01-08 US US12/812,165 patent/US8674084B2/en active Active
- 2009-01-08 ES ES09700649.8T patent/ES2537198T3/es active Active
- 2009-01-08 RU RU2010133217/10A patent/RU2539793C2/ru not_active Application Discontinuation
- 2009-01-08 AU AU2009203608A patent/AU2009203608B2/en not_active Ceased
- 2009-01-08 NZ NZ586939A patent/NZ586939A/xx not_active IP Right Cessation
-
2010
- 2010-06-24 IL IL206606A patent/IL206606A/en active IP Right Grant
- 2010-07-22 ZA ZA2010/05245A patent/ZA201005245B/en unknown
-
2014
- 2014-02-04 US US14/172,301 patent/US20140250549A1/en not_active Abandoned
-
2017
- 2017-08-11 US US15/674,881 patent/US10822613B2/en not_active Expired - Fee Related
-
2020
- 2020-08-31 US US17/007,242 patent/US10947549B2/en active Active
- 2020-09-09 US US17/016,191 patent/US20210155947A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20140250549A1 (en) | 2014-09-04 |
| US20200392522A1 (en) | 2020-12-17 |
| KR101602972B1 (ko) | 2016-03-11 |
| EP2240589B1 (en) | 2015-03-04 |
| MX2010007336A (es) | 2010-08-16 |
| CA2711895C (en) | 2016-08-09 |
| EP2240589A1 (en) | 2010-10-20 |
| RU2010133217A (ru) | 2012-02-20 |
| IL206606A (en) | 2015-11-30 |
| ES2537198T3 (es) | 2015-06-03 |
| BRPI0906509A2 (pt) | 2015-12-01 |
| CN101952446B (zh) | 2014-06-11 |
| AU2009203608A1 (en) | 2009-07-16 |
| CN101952446A (zh) | 2011-01-19 |
| US8674084B2 (en) | 2014-03-18 |
| JP5745857B2 (ja) | 2015-07-08 |
| JP2011509081A (ja) | 2011-03-24 |
| DK2240589T3 (en) | 2015-05-04 |
| US10822613B2 (en) | 2020-11-03 |
| IL206606A0 (en) | 2010-12-30 |
| AU2009203608B2 (en) | 2014-03-27 |
| KR20100109950A (ko) | 2010-10-11 |
| CA2711895A1 (en) | 2009-07-16 |
| US20210155947A1 (en) | 2021-05-27 |
| US10947549B2 (en) | 2021-03-16 |
| PT2240589E (pt) | 2015-06-18 |
| US20180030462A1 (en) | 2018-02-01 |
| US20100287670A1 (en) | 2010-11-11 |
| ZA201005245B (en) | 2012-01-25 |
| RU2539793C2 (ru) | 2015-01-27 |
| WO2009087391A1 (en) | 2009-07-16 |
| GB0800272D0 (en) | 2008-02-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 08 JAN 2016 BY HENRY HUGHES Effective date: 20130205 |
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